• Journal of Ginseng Research
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• 제45권1호
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• pp.41-47
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• 2021

A wide range of studies have steadily pointed out the relation of oxidative stress to the primary and secondary causes of human disease and aging. As such, there have been multiple misconceptions about oxidative stress. Most of reactive oxygen species (ROS) generated from chronic diseases cause oxidative damage to cell membrane lipids and proteins. ROS production is increased by abnormal stimulation inside and outside in the body, and even though ROS are generated in cells in response to abnormal metabolic processes such as disease, it does not mean that they directly contribute to the pathogenesis of a disease. Therefore, the focus of treatment should not be on ROS production itself but on the prevention and treatment of diseases linked to ROS production, including types 1 and 2 diabetes, cancer, heart disease, schizophrenia, Parkinson's disease, and Alzheimer's disease. In this regard, Korean Red Ginseng (KRG) has been traditionally utilized to help prevent and treat diseases such as diabetes, cancer, inflammation, nervous system diseases, cardiovascular disease, and hyperlipidemia. Therefore, this review was intended to summarize in vivo animal and human clinical studies on the antioxidant activities of KRG and its components, ginsenosides.

• Tuberculosis and Respiratory Diseases
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• 제73권4호
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• pp.204-209
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• 2012

Background: We investigated whether chrysin affected MUC5AC mucin production and gene expression induced by phorbol ester (phorbol 12-myristate 13-acetate, PMA) or epidermal growth factor (EGF) from human airway epithelial cells. Methods: Confluent NCI-H292 cells were pretreated with varying concentrations of chrysin for 30 minutes, and were then stimulated with PMA and EGF for 24 hours, respectively. MUC5AC mucin gene expression and mucin protein production were measured by reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay. Results: Concentrations of $10{\mu}M$ and $100{\mu}M$ chrysin were found to inhibit the production of MUC5AC mucin protein induced by PMA; A concentration of $100{\mu}M$ chrysin also inhibited the production of MUC5AC mucin protein induced by EGF; $100{\mu}M$ chrysin inhibited the expression of MUC5AC mucin gene induced by PMA or EGF. The cytotoxicity of chrysin was checked by lactate dehydrogenase assay, and there was no cytotoxic effect observed for chrysin. Conclusion: These results suggest that chrysin can inhibit mucin gene expression and the production of mucin protein by directly acting on airway epithelial cells.

• 천문학논총
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• 제27권4호
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• pp.281-284
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• 2012

We utilize AKARI's slitless spectroscopic capability to detect the $3.3{\mu}m$ polycyclic aromatic hydrocarbons (PAHs) emission and measure star formation (SF) activity for various AKARI programs. First, we obtain $2{\sim}5{\mu}m$ spectra of 20 flux-limited galaxies with mixed SED classes in order to calibrate the $3.3{\mu}m$ PAH luminosity ($L_{PAH3.3}$) as a star formation rate (SFR) indicator. We find that $L_{PAH3.3}$ correlates with $L_{IR}$ as well as with the $6.2{\mu}m$ PAH luminosity ($L_{PAH6.2}$). The correlations does not depend on SED classes. We find that ULIRGs deviate from the correlation between PAH luminosities and $L_{IR}$, while they do not for the correlation between PAH luminosities. We suggest possible effects to cause this deviation. On the other hand, how AGN activity is linked to SB activity is one of the most intriguing questions. While it is suggested that AGN luminosity of quasars correlates with starburst (SB) luminosity, it is still unclear how AGN activity is connected to SF activity based on host galaxy properties. We are measuring SFRs for the LQSONG sample consisting of reverberation mapped AGNs and PG-QSOs. This is an extension of the ASCSG program by which we investigated the connection between SB and AGN activities for Seyferts type 1s at z ~ 0.36. While we found no strong correlation between $L_{PAH3.3}$ and AGN luminosity for these Seyferts 1s, $L_{PAH3.3}$ measured from the central part of galaxies correlates with AGN luminosity, implying that SB and AGN activities are directly connected in the nuclear region.

• 한국유체기계학회 논문집
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• 제10권2호
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• pp.41-45
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• 2007

The shutoff unit was designed to provide rapid insertion of neutron absorbing material into the reactor core to shutdown the reactor quickly and also to withdraw the absorber slowly to avoid a log-rate trip. Four shutoff units were installed on the HANARO reactor but the half-core test facility was equipped with one shutoff unit. The reactor trip or shutdown is accomplished by four shutoff units by insertion of the shutoff rods. The shutoff rod(SOR) is actuated by a directly linked hydraulic cylinder on the reactor chimney, which is pressurized by a hydraulic pump. The rod is released to drop by gravity, when triplicate solenoid valves are de-energized to vent the cylinder. The hydraulic pump, pipe and air supply system are provided to be similar with the HANARO reactor. The shutoff rod drops for 647mm stroke within 1.13 seconds to shut down the reactor and it is slowly inserted to the full down position, 700mm, with a damping. We have conducted the drop test of the shutoff rod in order to show the performance and the structural integrity of operating system of the shutoff unit. The present paper deals with the 647mm drop time and the withdrawal time according to variation of the pool water temperature, the water level and the core flow.

• Bulletin of the Korean Chemical Society
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• 제32권4호
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• pp.1298-1302
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• 2011

This study describes the development of an electrochemical array immunochip for the detection of IgG. Interdigitated immunochip platforms were fabricated by sputtering gold on a glass wafer by using MEMS process and then were coated with Eudragit S100, an enteric polymer, forming an insulating layer over the working area of immunochips. The breakdown of the polymer layer was exemplified by the catalytic action of urease which, in the presence of urea, caused an alkaline pH change. This subsequently caused an increase of the double layer capacitance of the underlying electrode. Used in conjunction with a competitive immunoassay format, this allowed the ratio of initial to final electrode capacitance to be directly linked with the concentration of analyte, i.e. IgG. Responses to IgG could be detected at IgG concentration as low as $250\;ngmL^{-1}$ and showed good linearity up to IgG concentration as high as $20\;{\mu}gmL^{-1}$.

• 농촌계획
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• 제14권4호
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• pp.11-19
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• 2008

The layer technique is to produce many memorable scenes by generating layers of new experiences on the existing ones as it is adding the cognitive layers on to the visually seen landscape. Its need is high for places whose landscape itself influences perception, value or expression and which determines the spatial and quality standards. The existing floor plan-based design methods have failed to be useful in generating complex visual experiences. In order to maximize the aesthetical landscape experiences in landscape planning, cognitive layers are needed which complement the input of adequate cognitive elements and the inter-element relationships. Here, layers are utilized to change the arrangement of the landscape elements and coordinate the cognitive flow so that the images could be connected and imagination could occur. A case in point is Anhyun Village in Gochang where physically distinctive layers are additionally set to make a visual experience enriching. The new landscape layers discover the fact that it provides diversity in experiencing the village landscape and forming the sense of beauty and that it is deeply immersed into the daily life of the village. Meanwhile, Guwau Village in Taebaek is an example showing the usefulness of various-layer setting in landscape planning in setting effective circulation planning. That is, the bottom line is the spacing-starting where and making it stay where for a few seconds, and the visual layers. It is also critical to encourage inducing circulation so that layers of the senses stimulating five senses could intervene. Lastly, Mulgeon-ri in Namhae is a case which directly made a parallel of the physical layers of the landscape composition and the cognitive layers of the landscape experience. Artificial landscape planning is mostly about manipulating of visual traits that people feel beautiful, but the layer technique is linked to how to make experiences enriching and renewed.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2009년도 제40회 하계학술대회
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• pp.1658_1659
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• 2009

PLS(Pohang Light Source) will begin the PLS-II project that has been funded by the KOREA Government in order to further upgrade the PLS which has operated since 1992. The control system of the PLS-II has distributed control architecture, with two layers of hierarchy; operator interface computer (OIC) layer and machine interface computer (MIC) layer. The OIC layer is based on SUN workstation with UNIX. A number of PC-based consoles allow to remotely operating the machine from the control room. PC-based consoles use the Linux or Windows operation system. Similar consoles in the experimental hall are used to control experiments. The MIC layer is directly interfaced to individual machine devices for low-level data acquisition and control. MIC layer is based on VMEbus standard with vxWorks real-time operating system. Executable application software modules are downloaded from host computers at the system start-up time. The MIC's and host computers are linked through Ethernet network. It should enable the use of hardware and software already developed for specific light source requirements. The core of the EPICS (Experimental Physics and Industrial Control System)[1] has been chosen as the basis for the control system software.

• Toxicological Research
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• 제17권
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• pp.227-236
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• 2001

The IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans has reviewed, summarized and evaluated 869 environmental agents and exposures as oj June 2000. This large collection includes all relevant published epidemiological data on cancer in exposed humans and results of bioassays for carcinogenicity in experimental animals. Since 1986. cancer data have been systematically supplemented by summaries of other toxicological data that are relevant to assessments of carcinogenic hazard. These include summaries qf genetic and related effects of chemicals. which have been prepared as Genetic Activity Profiles (GAP) by the U.S. EPA in collaboration with IARC. As the Mono-graphs have proved increasingly valuable and influential worldwide. they have evolved into an encyclopedia on environmental carcinogenic risks to humans. However. the Monographs have historically been prepared only as printed books with limited distribution. and the Monographs Programme has needed to adjust to expectations oj wider availability. Since 1998 the evaluations and summaries have been globally accessible by Internet from IARC (http://www.iarc.fr) and the GAP profiles by Internet from EPA (http://www.epa.gov/gapdb/). with the two web sites linked. Improved EPN/ARC GAP database and software. GAP2000. now link GAP profiles directly to the appropriate IARC web pages for summaries of evaluations of a given compound and its overall IARC classification. During the year 2000. by means of optical character recognition (OCR) technology the entire series of IARC Monographs is being converted to an electronic version. The first edition is now available commercially in CD-ROM format and will soon become available on-line at .

• 한국콘텐츠학회논문지
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• 제13권6호
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• pp.469-480
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• 2013

본 논문은 제주관광과 직 간접적적으로 연계되어 있는 관광패키지 가격 메커니즘의 의사결정에 관한 연구로 제주도 관광패키지 12개의 상품을 선정하여 전망이론에 기초한 심리적 회계원칙과 프레이밍 효과를 One Way ANOVA 검정방법으로 분석하고 있다. 분석 결과, 첫째, 관광패키지 리스트가격정보를 제시할 때 묶음가격으로 제시하는 마케팅 전략이 필요하다. 둘째, 할인가격 정보는 기본패키지와 옵션패키지의 개별할인 정보를 단위별로 세분하여 공개하는 것이 바람직하다. 셋째, 가격(가격할인)정보 제공에서 관광상품 구매경험이 풍부한 관광객들은 경험이 적은 고객들보다 가격정보에 민감한 것으로 나타나 "프레이밍 효과"와 "지식-조합이론"이 일치하는 결과가 도출되었다. 따라서 리스트가격정보는 묶음가격으로 제시하는 한편, 가격할인상품은 할인정보를 어떠한 프레임으로 제시하느냐가 중요하며, 현대인의 관광상품 구매 관점을 파악하는 것과 시간, 노력, 바용 등이 절약될 수 있는 여행서비스상품을 제공하여 심리적 회계원칙에 안정감을 주는 것이 필요한 것으로 분석되었다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2018년도 춘계학술대회
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• pp.341-343
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• 2018

농업은 여러 산업 중에서 가장 오랜 역사를 가지고 있으며, 인류의 발달에 직, 간접적으로 연관되어 있다. 그러나 최근 우리나라의 농업은 농촌인구의 감소 및 고령화, 자재비용 상승 및 한반도 기후 변화로 인해 농가 경영에 어려움이 있다. 이러한 문제점을 해결하기 위해 ICT를 이용한 스마트 농장이 대안으로 제시된다. 스마트 농장은 다양한 센서를 통하여 농장의 온도 관리 및 급수장치를 관리하나, 작물에 따른 섬세한 관리에 한계가 있다. 따라서, 본 논문에서는 기존 수분센서와 달리 토양의 깊이에 따라 수분 공급을 달리하여 식물의 생장에 최적화된 환경을 구현하였다.