• The Journal of Advanced Prosthodontics
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• v.1 no.1
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• pp.56-61
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• 2009

STATEMENT OF PROBLEM. The success of titanium implants is due to osseointegration or the direct contact of the implant surface and bone without a fibrous connective tissue interface. PURPOSE. The purpose of this study was to evaluate the osteoblast precursor response to titanium-10 tantalum-10 niobium(Ti-Ta-Nb) alloy and its sputtered coating. MATERIAL AND METHODS. Ti-Ta-Nb coatings were sputtered onto the Ti-Ta-Nb disks. Ti6-Al-4V alloy disks were used as controls. An osteoblast precursor cell line, were used to evaluate the cell responses to the 3 groups. Cell attachment was measured using coulter counter and the cell morphology during attachment period was observed using fluorescent microscopy. Cell culture was performed at 4, 8, 12 and 16 days. RESULTS. The sputtered Ti-Ta-Nb coatings consisted of dense nanoscale grains in the range of 30 to 100 nm with alpha-Ti crystal structure. The Ti-Ta-Nb disks and its sputtered nanoscale coatings exhibited greater hydrophilicity and rougher surfaces compared to the Ti-6Al-4V disks. The sputtered nanoscale Ti-Ta-Nb coatings exhibited significantly greater cell attachment compared to Ti-6Al-4V and Ti-Ta-Nb disks. Nanoscale Ti-Ta-Nb coatings exhibited significantly greater ALP specific activity and total protein production compared to the other 2 groups CONCLUSIONS. It was concluded that nanoscale Ti-Ta-Nb coatings enhance cell adhesion. In addition, Ti-Ta-Nb alloy and its nanoscale coatings enhanced osteoblast differentiation, but did not support osteoblast precursor proliferation compared to Ti-6Al-4V. These results indicate that the new developed Ti-Ta-Nb alloy and its nanoscale Ti-Ta-Nb coatings may be useful as an implant material.

• Biomaterials and Biomechanics in Bioengineering
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• v.3 no.1
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• pp.27-35
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• 2016

Anterior knee pain is a major problem among adolescents and young adults especially those who participates in sports. The most common pathogenesis of anterior knee pain can arise from compression and shear forces in the patellofemoral joint. It is also caused by impingement of infrapatellar fat pad. Fat pad impingement can occur when the fat pad becomes swollen and inflamed due to a direct blow or chronic irritation. As a result, the bottom tip (or inferior pole) of the patella can pinch the fat pad. One of the many causes of swollen fat pad can be secondary to anterior cruciate ligament (ACL) injury. The aim of this study was to compare the infrapatellar fat pad volume in patients with acute ACL injury and a group of age-, gender-, and activity- matched controls with intact ligament. Axial magnetic resonance (MR) images have been performed on 32 patients with torn ACL and 40 control patients. The volume of the fat pad was measured digitally from MR image by using a 3d Reconstruction software, ellipsoidal approximation, and a MATLAB code. The results were compared between patients with torn ACL and control group. Patients with a torn ACL had a significantly larger fat pad than the controls (P=0.01). There was no significant difference between the methods used to measure the infrapatellar fat pad volume (P=0.83-0.87). Thus, lesions of the infrapatellar fat pad is often associated with ACL injury.

• Journal of Korea Society of Industrial Information Systems
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• v.4 no.2
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• pp.62-72
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• 1999

We consider a Direct Input Output Manufacturing System(DIOMS) which has a munber of machine centers placed along a built-in Automated Storage/Retrieval System(AS/RS). The Storage/Retrieval(S/R) machine handles parts placed on pallets for the machine centers located at either one or both sides of the AS/RS. This paper deals with the operational aspect of DIOMS and determines the optimal operating policy by combining computer simulation and genetic algorithm. The operational problem includes: input sequencing control, dispatching rule of the S/R machine, machine center-based part type selection rule and storage assignment policy. For each operating policy, several different policies are considered based on the known research results. In this paper, using the computer simulation and genetic algorithm we suggest a method which gives the optimal configuration of operating policies within reasonable computation time.

• Journal of Pharmacopuncture
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• v.23 no.3
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• pp.165-172
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• 2020

Objectives: In the past few years, herbal medicines have gained popularity over synthetic drugs because of their natural source and minimal side effects which has led to a tremendous growth of phytopharmaceuticals usage. With the development of nanotechnology, it provides alternative approaches to overcome several limitations using nano-formulations. In spite of considerable quantity of antianemic preparations with different iron forms available, currently additives are used and represented in modern pharmaceutical market. Iron deficiency anemia is a major global public health problem which particularly affects pregnant women, children and elderly persons. The situation is complicated because of disadvantages and drug side effects from existing antianemic medicines. There is a great demand for the development of new antianemic preparations. Green synthesis of iron oxide nanoparticles, possess high potential in this field. Methods: Our study focuses on developing green synthesis of iron oxide nanoparticles (IONPs) of 10-50 nm with spherical shape where different dosages were used -1 mg/kg, 10 mg/kg and 100 mg/kg for exposure in Wistar albino female rats for 28 days. The toxicity was assessed using various parameters such as measurements of the rat body and organ mass, hematology, biochemical evaluation and histopathological examinations. Results: No significant differences were observed in body and organ weights. Hematological indices also indicated no significant differences whereas biochemical factors showed increase in levels of direct bilirubin and globulin of medium as well as high dose and SGPT levels were increased only in high dose. The major organs (heart, kidney and liver) showed histopathological alterations in 10 and 100 mg/kg whereas brain showed only in 100 mg/kg. Conclusion: The toxicity of IONPs was found to be more significant when the concentration was increased; however, low doses can be used for further investigation as an antianemic preparation.

• Transactions of the Korean hydrogen and new energy society
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• v.30 no.6
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• pp.567-577
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• 2019

Due to the depletion of fossil fuels and environmental pollution, demand for alternative energy is gradually increasing. Among the various methods, a method to convert biomass into alternative fuel has been proposed. The bio-fuel obtained from biomass through pyrolysis process is called pyrolysis oil (PO) or bio-oil. Because PO is difficult to use directly in conventional engines due to its poor fuel properties, various methods have been proposed to upgrade pyrolysis-oil. The simplest approach is to mix it with conventional fossil fuels. However, due to their different polarity of PO and fossil fuel, direct mixing is impossible. To resolve this problem, emulsification of two fuels with a proper surfactant was proposed, but it costs additional time and cost. Alternatively, the use of alcohol fuels as an organic solvent significantly improve the fuel properties such as fuel stability, calorific value and viscosity. In this study, blends of diesel, n-butanol, and coffee ground pyrolysis oil (CGPO) which is one of the promising PO, was applied to diesel generator. Combustion and emissions characteristics of blended fuels were investigated under the entire load range. Experimental results show that ignition delay is similar to that of diesel at high load. Although, hydrocarbon and carbon monoxide emissions are comparable to diesel, significant reduction of nitrogen oxides and particulate matter emissions were observed.

• Convergence Security Journal
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• v.13 no.4
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• pp.3-10
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• 2013

Cyber attacks are threats to national security. Today, cybersecurity threats have various types, the theft or spread of privacy and national secret, the realization of direct attacks to infrastructure and the hacktivism with political or social objectives. Furthermore, There are special situations in South Korea because of North Korea's threats. Thus, It is necessary to handle cybersecurity as a kind of national security problem. It is a time to identify problems of governance system in cybersecurity and to improve related Acts and subordinate statutes. There are several tasks for legal improvement for governance system in cybersecurity. They are improving legal bases for the roles of the relevant authorities in cybersecurity, consolidating national joint response to cyber accidents, establishing and vitalizing information sharing system, constructing foundation of cybersecurity through industry promotion and manpower development, and acquiring defensive tools by enhancement research an development. In order to address these challenges, it is necessary to pay much attention to enactment and to revision laws and to practice legislative procedure.

• KSBB Journal
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• v.16 no.2
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• pp.146-152
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• 2001

To avoid the intrinsic problem of aggregation associated with the traditional solution-phase refolding process, we propose a solid-phase refolding method integrated with expanded bed adsorption chromatography. The model protein used was a fusion protein of recombinant human growth hormone and a glutathione S transferase fragment. It was demonstrated that the EBA-mediated refolding technique could simultaneously remove cellular debris and directly renature the fusion protein inclusion bodies in the cell homogenate with much higher yields and less agregation. To demonstrate the applicability of the method, we successfully tested the three representative types of starting materials, i. e., rhGH monomer, washed inclusion bodies, and the E. coli homogenate. This direct and simplified refolding process could also reduce the number of renaturation steps required and allow refolding at a higher concentration, at approximately 2 mg fusion protein per ml of resin. To the best of our knowledge, it is the first approach that has combined the solid-phase refolding method with expanded bed chromatography.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.51 no.10
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• pp.485-491
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• 2002

Since Wertheimer and Leeper reported possible adverse health effects of magnetic field in 1979, worldwide researches on this issue have been conducted. More recently, the U.S. Congress instructed the NIEHS (National Institute of Environmental Health Sciences), NIH (National Institute of Health) and DOE (Department of Energy) to direct and manage EMF RAPID (Electric and Magnetic Fields Research and Public Information Dissemination) program aimed at providing scientific evidence to clarify the potential for health risks from exposure to extremely low frequency electric and magnetic fields(ELF-EMF). Although they concluded that the scientific evidence suggesting adverse health risks of ELF-EMF is weak, the exposure to ELF-EMF cannot be recognized as entirely safe. Therefore, the purpose of this article is to describe magnetic field 3-D calculation and to evluate eddy current of human body compare to international guide line recognized one of the basic problems. In open boundary problem, Magnetic field using FEM is not advantageous in the point of the division of area and the proposition of the fictitious boundary. Therefore, we induced the analytic equation of magnetic field calculations so but the finite line segment based on Biot-Savarts law Also, Eddy currents induced due to ELF-EMF magnetic field are computed. To calculate induced currents, impedance method is used in this paper, An example model of human head with resolution of 1.27cm is used. In this paper, We evaluate the magnetic field and eddy current of human head around 765 kV transmission lines compare to international guide line.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.17 no.3
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• pp.64-72
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• 2003

Comparing with transmission networks, the faults in distribution networks more often occurs because of the complicated structure and the adjacency to customers. Moreover the faults give direct damage to customers. So fault diagnosis and blackout restoration in distribution networks are very important elements to reduce the damage of customers and to maintain the stability. The restoration problem of distribution networks is subject to time. Minimizing the switching numbers in restoration process is the crucial element. In other words. the best restoration is to restore all blackout area through just one switching, if not the restoration has to be accomplished through several switching. This paper proposes the efficient restoration system in distribution networks to minimize the switching numbers. The proposed system uses the dynamic division method of hierarchical structure which consists of heuristic searching method and meta algorithm. The proposed system is applied to the sample networks, and the results showed a promising possibility.

• KIPS Transactions on Computer and Communication Systems
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• v.9 no.9
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• pp.189-196
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• 2020

Recently, GPU cloud computing technology applying GPU(Graphics Processing Unit) devices to virtual machines is widely used in the cloud environment. In a cloud environment, GPU devices assigned to virtual machines can perform operations faster than CPUs through massively parallel processing, which can provide many benefits when operating high-performance computing services in a variety of fields in a cloud environment. In a cloud environment, a GPU device can help improve the performance of a virtual machine, but the virtual machine scheduler, which is based on the CPU usage time of a virtual machine, does not take into account GPU device usage time, affecting the performance of other virtual machines. In this paper, we test and analyze the performance degradation of other virtual machines due to the virtual machine that performs GPGPU(General-Purpose computing on Graphics Processing Units) task in the direct path based GPU virtualization environment, which is often used when assigning GPUs to virtual machines in cloud environments. Then to solve this problem, we propose a GPGPU task management method for a virtual machine.