• 지질공학
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• 제16권2호
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• pp.135-143
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• 2006

강우에 의한 사면파괴의 초기단계 및 과정을 규명하기 위하여 실내 사면모델 시험결과를 분석하였다. 이 파괴 초기단계와 관련된 수리학적 상호관계를 파악하기 위해 인공강우 살포동안 사면모델 내 체적함수비 변화를 측정하는데 목적을 두었다. 사면파괴의 과정은 인공강우동안 사면 하단부의 유출면 발달에 의해 파괴를 발생시키는 요인으로 작용하였다. 따라서 국부적인 사면파괴를 예측하기 위해서는 강우에 의해 발생된 침투수의 침투특성에 대한 장기적인 계측이 매우 중요하다. 사면 내에서 강우에 의한 침윤선의 침투 및 지하수위 상승과 밀접한 연관성을 갖는 체적함수비 변화를 3가지의 침투변화(phase I, phase II, phase III로 나누어 사면파괴를 계측할 수 있는 수리학적 측면으로 접근하였다. 따라서 체적함수비가 급격히 증가하는 phase III 단계부터는 사면파괴 발생 가능성이 매우 증가함을 파악하였다. 그러므로 사면 내 체적함수비 변화를 연속적으로 계측함으로써 강우에 의한 사면파괴의 발생을 효율적이고 실질적으로 예측할 수 있을 것으로 판단된다.

• Smart Structures and Systems
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• 제26권5호
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• pp.605-617
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• 2020

In this study, the experimental tests for the direct tensile strength measurement of Ultra-High Performance Concrete (UHPC) were numerically modeled by using the discrete element method (circle type element) and Finite Element Method (FEM). The experimental tests used for the laboratory tensile strength measurement is the Compressive-to-Tensile Load Conversion (CTLC) device. In this paper, the failure process including the cracks initiation, propagation and coalescence studied and then the direct tensile strength of the UHPC specimens measured by the novel apparatus i.e., CTLC device. For this purpose, the UHPC member (each containing a central hole) prepared, and situated in the CTLC device which in turn placed in the universal testing machine. The direct tensile strength of the member is measured due to the direct tensile stress which is applied to this specimen by the CTLC device. This novel device transferring the applied compressive load to that of the tensile during the testing process. The UHPC beam specimen of size 150 × 60 × 190 mm and internal hole of 75 × 60 mm was used in this study. The rate of the applied compressive load to CTLC device through the universal testing machine was 0.02 MPa/s. The direct tensile strength of UHPC was found using a new formula based on the present analyses. The numerical simulation given in this study gives the tensile strength and failure behavior of the UHPC very close to those obtained experimentally by the CTLC device implemented in the universal testing machine. The percent variation between experimental results and numerical results was found as nearly 2%. PFC2D simulations of the direct tensile strength measuring specimen and ABAQUS simulation of the tested CTLC specimens both demonstrate the validity and capability of the proposed testing procedure for the direct tensile strength measurement of UHPC specimens.

• Journal of Microbiology
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• 제34권3호
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• pp.236-240
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• 1996

Rifampin is the most powerful drug for treating leprosy and tuberculosis today. It inhibits initiation and elongation of RNA transcription by binding to $\beta$-subunit of RNA polymerase, leading to kill mycobacteria. We isolated one variant strain of Mycobacterium leprae from 24 Korean leprosy patients who are less susceptible to rifampin or have suffered from relapse by polymerase chain reaction and single strand conformation polymorphism (PCR-SSCP) of the rpoB gene. Direct sequencing of the rpoB region of M. leprae variant revealed missense mutations which altered the amino acids sequenceof RpoB to Ser-464, Arg-465, Arg-467 and Ala-468. This is the first finding on rpoB gene mutation of M. leprae from Korean patients ; moreover the mutant type was found to be different from the previously reported cases in other countries.

• 한국작물학회지
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• 제44권1호
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• pp.44-48
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• 1999

Uptake, assimilation and translocation of nitrogen and dry matter assimilation and translocation in ten rice cultivars were observed in no-till direct-sown rice-vetch cropping system. There was a large degree of variation in N-uptake, grain yield, nitrogen translocation efficiency and dry matter assimilation and translocation in tested rice cultivars. Forty kg N/ha base, as compound fertilizer (21-17-21% of N-P-K) three weeks after sowing and 30 kg N/ha top-dressed at panicle initiation stage as in the form of (NH$_4$)$_2$$CO_2$ was applied. ‘Newbounet’, ‘Daesanbyeo’, and ‘Hwayeongbyeo’ showed higher translocation efficiency. The contribution of pre-heading dry matter assimilates to grain ranged from 33% to 99% of dry grain weight. Dry matter of ‘Calrose 76’ was lower than Newbounet but N content was higher in Calrose 76 than Newbonnet. By maturity, N content in vegetative parts declined considerably more than dry matter, vegetative and reproductive parts, N translocation efficiency, and N harvest index. Nitrogen translocation efficiency was greater in ‘Nonganbyeo’, Daesanbyeo, and Newbounet. Grain N concentration was positively correlated with N concentration or N content of the vegetative parts at heading in Nonganbyeo, ‘Dasanbyeo’, ‘Dongjinbyeo’, and Newbonnet. These results indicated that the greater amount of dry matter and N accumulated before heading stage, the higher translocation rates of dry matter to grain and the greater net losses at maturity.

• 한국유기농업학회지
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• 제7권2호
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• pp.153-161
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• 1999

No-till direct-sown rice-wheat relaying cropping system has major advantages such as labor and cost saving by eliminating tillage and preparation of seed bed and transplanting. In this system, rice sowing was done simultaneously wheat harvesting. A paddy field experiment was conducted to evaluate effects of no-till years on soil microbial changes and soil physico-chemical characteristics with rice growth and development. Chemical fertilizers and agricultrual chemicals was not applied in no-till system. As the year in no-till direct-sown system the air permeability was increased and after water submerging soluble nitrogen was released Aerobic microbial-n was highest in May and then decreased after water irrigation. The population of aerobic soil microorganisms were steeply decreased after water submerging Soil microorganisms was decreased with the increased the soil depth. A month was needed for the seedling establishment in a no-tillage rice-wheat cropping system. Increased cropping years improved leaf greenness and leaf area index(LAI). But stomatal conductance(Gc) was higher in conventional cultivation system than no-till system. Stomatal conductance at panicle initiation stage was increased higher in conventional condition of leaves but the difference between conventional and no-till system was increased at heading stage. In no-till 4 years condition rice grain yield was spikelet numbers per panicle.

• 정보처리학회논문지C
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• 제11C권3호
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• pp.371-378
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• 2004

IETF(Internet Engineering Task Force)에서 제안한 SIP(Session Initiation Protocol)는 텍스트 기반의 프로토콜로서 유연성과 뛰어난 확장성을 가지고 있어 다양한 응용 서비스에 적용할 수 있는 호 설정 프로토콜이다. 본 논문에서는 이러한 SIP를 기반으로 하여 사용자의 현재 상태에 관련된 정보를 알려주는 Presence 서비스 및 Presence 서비스에서의 Watcher 정보 서비스도 아울러 포함시킨 통합 인스턴트 메신저 시스템을 구현하였다. 이 시스템에서는 텍스트 기반의 인스턴트 메시지뿐만 아니라 음성 및 화상 통신도 가능하도록 하였다. 그리고 음성 및 화상통신의 경우 Presence 정보를 담는 PRESENCE TUPLE을 확장하여 Presence 서버가 통신에 필요한 각종 세션 정보를 저장하도록 함으로써 SIP INVITE 요청 메시지를 통한 다이얼로그의 생성 없이 직접 사용자간의 연결이 가능하도록 하는 새로운 방법을 제시하였다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제20권1호
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• pp.55-60
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• 2017

Intestinal hypoganglionosis is a rare innervation disorder that provides numerous nutritional, medical and surgical challenges. In this case report, we present a case of a newborn with intestinal hypoganglionosis leading to intestinal failure and intestinal failure-associated liver disease who responded to $Omegaven^{TM}$, a fat emulsion comprised of omega-3 fatty acids. $Omegaven^{TM}$ has been shown to be beneficial in the management of cholestatic liver injury. Clinical success with $Omegaven^{TM}$ was seen in this patient with a clear decrease in aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and complete resolution of cholestasis with a direct bilirubin of zero within two weeks of initiation of $Omegaven^{TM}$. No current guidelines for the diagnosis and management of hypoganglionosis are available. We recommend a multidisciplinary approach and the use of novel therapies such as fat emulsions composed of omega-3 fatty acids for improved patient outcomes. Appropriate compassionate use protocols should be obtained from the Food and Drug Administration prior to initiation of $Omegaven^{TM}$.

• 대한가정학회지
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• 제34권3호
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• pp.305-325
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• 1996

This study was designed to compare mothers' beliefs of literacy development and home literacy environment and to explore how the children interacted with their mother during literacy activities and how they used the strategies to develop knowledge of literacy. The qualitative data was collected from multiple sources of naturalistic information and analyzed through triangulation of diverse methods including participant observations in the home, parental during literacy events, written logs kept by the mothers, the children's writing products, three emergent assessment forms, and photographs. The three preschoolers and their mothers provided different literacy experiences to support their children's emerging conventional literacy development. Child 1's mother highly valued the rich home literacy environment and the child 1's initiative interactions during literacy events. Child 3's home literacy context was very similar to her Montessori classroom's phonic approach and writing skills. Child 2 was provided with an inappropriate literacy environment at home through direct instruction and an emphasis on correct writing. All of the children were interested and attended to story. Child 1 interacted with her mother in expanded cycles as child's initiation, mother's clarification, and child's evaluation, compared with the child 2's simple cycle and the child 3's classroom-like cycle as mother's initiation, child's response, and mother's evaluation. The children and their mothers employed a number of diverse strategies to understand knowledge of literacy. Importantly parent education needs to emphasize the importance of playful one to one mother-child interaction, a functional holistic literacy environment., and strategies for expanding child's knowledge with parent as mediator.

• Toxicological Research
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• 제13권1_2호
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• pp.23-27
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• 1997

This study was performed to examine the anti-cancer effect of Red Ginseng in the DENGalN-PH-induced hepatic tumor model system in rats. One hundred of male SPF Sprague-Dawley rats(6weeks old) were randomly divided into five groups. Rats in groups 1, 2, 3, and 4 were administered to diethylnitrosamine intraperitoneally 200 mg/kg body weight for the caner initiation. Rats in group 5 were given to saline as a control. On two weeks after cancer initiation, rats in groups 1 and 3 were fed on diet containing 0.01% of acethylaminofiuorene(AAF) which is strong cancer-promotor for 6 weeks, while rats in groups 2 and 4 were fed on water containing 0.05% of phenobarbital which is weak cancer.promotor for 6 weeks. Rats in groups 1 and 2 were treated with diet containing 3% of Red Ginseng for six weeks(from 9th week till 15th week after cancer initiation). Rats in all groups were necropsied time-sequencially at 8, 15, and 36 weeks. The hepatic lesions of rat treated with carcinogens expressed glutathione S-transferase placental form(GST-P) at 8 week. The GST-P positive foci of rats treated with AAF were larger than that of any other rats, while the GST-P positive foci of rats treated with AAF and red ginseng were significantly decreased. This anti-cancer effect of Red ginseng might be involved in the enhacement of natural killer cell activity. To know whether there is direct relationship between Red Ginseng and natural killer cell activity, the activity of natural killer cell was examined after treatment AAF, AAF+Red ginseng and Red ginseng only, respectively. Comparing with natural killer cell activity in AAF-treated group, natural killer cell activity was significantly activated in AAF+ Red ginseng-treated group. This indicated that Red ginseng might enhance natural killer activity after treatment carcinogen in rats. These results suggested that Red ginseng might have a cancer prevention ability by promoting natural killer cell activity during hepatocarclnogenesis.

• Journal of Microbiology and Biotechnology
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• 제20권8호
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• pp.1163-1178
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• 2010

Plasmids play important roles in horizontal gene transfer among Vibrionaceae, but surprisingly little is known about their replication and incompatibility systems. In this study, we successfully developed a bioinformatics-assisted strategy of experimental identification of seven Vibrio plasmid replicons. Comparative sequences analysis of the seven Vibrio plasmid replicons obtained in this study together with eight published Vibrionaceae plasmid sequences revealed replication-participating elements involved in the ColE1 mode of replication initiation and regulation. Like plasmid ColE1, these Vibrionaceae plasmids encode two RNA species (the primer RNA and the antisense RNA) for replication initiation and regulation, and as a result, the 15 Vibrionaceae plasmids were designated as ColE1-like Vibrionaceae (CLV) plasmids. Two subgroups were obtained for the 15 CLV plasmids, based on comparison of replicon organization and phylogenetic analysis of replication regions. Coexistence of CLV plasmids were demonstrated by direct sequencing analysis and Southern hybridization, strongly suggesting that the incompatibility of CLV plasmids is determined mainly by the RNA I species like the ColE1-like plasmids. Sequences resembling the conserved Xer recombination sites were also identified on the CLV plasmids, indicating that the CLV plasmids probably use the host site-specific recombination system for multimer resolution like that used by ColE1-like plasmids. All the results indicated that the 15 plasmids form a new ColE1-like group, providing a basis for the rapid characterization and classification of Vibrionaceae plasmids.