• Journal of Genetic Medicine
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• 제11권2호
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• pp.43-48
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• 2014

Chorionic villus sampling has gained importance as a tool for early cytogenetic diagnosis with a shift toward first trimester screening. First trimester screening using nuchal translucency and biomarkers is effective for screening. Chorionic villus sampling generally is performed at 10-12 weeks by either the transcervical or transabdominal approach. There are two methods of analysis; the direct method and the culture method. While the direct method may prevent maternal cell contamination, the culture method may be more representative of the true fetal karyotype. There is a concern for mosaicism which occurs in approximately 1% of cases, and mosaic results require genetic counseling and follow-up amniocentesis or fetal blood sampling. In terms of complications, procedure-related pregnancy loss rates may be the same as those for amniocentesis when undertaken in experienced centers. When the procedure is performed after 9 weeks gestation, the risk of limb reduction is not greater than the risk in the general population. At present, chorionic villus sampling is the gold standard method for early fetal karyotyping; however, we anticipate that improvements in noninvasive prenatal testing methods, such as cell free fetal DNA testing, will reduce the need for invasive procedures in the near future.

• 수산경영론집
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• 제42권1호
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• pp.71-83
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• 2011

An ecosystem-based fisheries management (EBFM) approach becomes more important as an alternative management method for a sustainable development of fisheries domestically and internationally. Many methods of applying a practical EBFM to fisheries management have been investigated, and considerable attention has been given to developing effective indicators of the present status of and changes in ecosystems and putting them to practical use. Among ecosystem indicators, developing socioeconomic indicators for EBFM is particularly important. This is because socioeconomic factors have direct effects on ecosystems, and ecosystems have direct effects on socioeconomic factors. Therefore, it is imperative that socioeconomic indicators are developed and evaluated in order to predict changes in ecosystems and to provide advice for effective fisheries management. This study is aimed to develop socioeconomic indicators which can be combined with biological and ecological indicators, in order to conduct the ecosystem-based fisheries assessment. In terms of socioeconomic indicators, five socioeconomic criteria were considered as important attributes of socioeconomic changes. These criteria include economical production, business conditions, income, market, and employment indicators. For evaluation of newly developed socioeconomic indicators, the Traffic Light System (TLS) method was used. In addition, on the basis of the application of developed indicators to the Korean large purse seine fishery, the socioeconomic conditions of the fishery and the usefulness of the indicators were evaluated and management implications were discussed.

• 대한기계학회논문집B
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• 제24권6호
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• pp.860-869
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• 2000

Numerical and experimental investigations are performed for the molecular transition and slip flows in pumping channels of a disk-type drag pump. The flow occurring in the pumping channel develops from the molecular transition to the slip flow traveling downstream. Two different numerical methods are used in this analysis: the first one is a continuum approach in solving the Navier-Stokes equations with slip boundary conditions, and the second one is a stochastic approach through the use of the direct simulation Monte Carlo method. In the experimental study, the inlet pressures are measured for various outlet pressures in the range of 0.1{\sim}4Torr. From the present study, the numerical results of predicting the performance, obtained by both methods, agree well with the experimental data for the range of Knudsen number $Kn{\leq}0.1$ (i.e., the slip flow regime). But the results from the second method only agree with the experimental data for Kn>0.1(i.e., the molecular transition regime)

• International Journal of Naval Architecture and Ocean Engineering
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• 제11권1호
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• pp.572-583
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• 2019

This paper aims to assess the applicability of the Runge Kutta Discontinuous Galerkin-Direct Ghost Fluid Method to the internal explosion inside a water-filled tube, which previously was studied by many researchers in separate works. Once the explosive charge located at the inner center of the water-filled tube explodes, the tube wall is subjected to an extremely high intensity fluid loading and deformed. The deformation causes a modification of the field of fluid flow in the region near the water-structure interface so that has substantial influence on the response of the structure. To connect the structure and the fluid, valid data exchanges along the interface are essential. Classical fluid structure interaction simulations usually employ a matched meshing scheme which discretizes the fluid and structure domains using a single mesh density. The computational cost of fluid structure interaction simulations is usually governed by the structure because the size of time step may be determined by the density of structure mesh. The finer mesh density, the better solution, but more expensive computational cost. To reduce such computational cost, a non-matched meshing scheme which allows for different mesh densities is employed. The coupled numerical approach of this paper has fewer difficulties in the implementation and computation, compared to gas dynamics based approach which requires complicated analytical manipulations. It can also be applied to wider compressible, inviscid fluid flow analyses often found in underwater explosion events.

• 한국강구조학회 논문집
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• 제25권5호
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• pp.487-495
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• 2013

국내 현실을 고려한 직접해석법 적용 방안의 제안을 위한 기초 연구로 국내의 강구조물 제작 및 설치시 적용되는 초기변형 허용값을 반영한 직접해석법 적용의 타당성을 해석적으로 평가하였다. 해석의 주요 변수로는 골조의 규모, 축력비, 축력분포, 가상하중 크기, 가상하중 가력 위치, 최소수평하중 개념 적용 여부 등을 적용하였다. 수치해석적 연구 결과 국내 초기변형 허용값인 L/700의 적용은 타당한 것으로 나타났으며, 이를 위한 방안으로 초기변형 허용값 L/700에 근거한 가상하중을 B2계수의 결과가 1.5 이하이고 수평하중이 존재하는 경우에라도 수평하중과 가상하중간에 최소수평하중 개념을 이용하여 층수평하중 형태로 가력하는 방법을 제안하였다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 하계학술대회 논문집 D
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• pp.2668-2670
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• 2004

This paper presents an advanced load control method in Direct Load Control(DLC) system. It is important to aggregate a various demand side resource which is surely controllable at the peak power time for a successful DLC system. Because the DLC system use simple On/Off control that may cause a harmful effect on a plant to reduce a peak power load, there are some restriction on deriving a voluntary participation of demand side resource. So it needs a new approach to direct load control method, and this paper describes an advanced load control method using control logic which is based on load properties. This method is easy to take account of a various characteristic of load, it can be use as a dynamic control logic which is good for adaptive control. The suggested control logic method is verified by modeling a control logic for a turbo refrigerator which affects on peak power in summer season.

• 전기학회논문지
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• 제56권4호
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• pp.795-798
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• 2007

In this paper, we propose an image reconstruction method utilizing an optimized adaptive interpolation kernel along with a 2D M-channel perfect reconstruction filter bank (M-ch PR-FB) structure. In particular, the proposed approach leads to construction of a sharper image than a direct conversion, still preserving high frequency components of the original image through the subband processing of the 2D M-ch PR-FB. Finally, the image quality of the proposed approach is demonstrated by comparing with those of the direct methods using conventional interpolation kernels.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• 제25권3호
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• pp.117-131
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• 2021

The problem of generalized thermoelasticity of two-temperature for finite piezoelectric rod will be modified by applying three different types of heating applications namely, thermal shock, ramp-type heating and harmonically vary heating. The solutions will be derived with direct approach by the application of Laplace transform and the Caputo-Fabrizio fractional order derivative. The inverse Laplace transforms are numerically evaluated with the help of a method formulated on Fourier series expansion. The results obtained for the conductive temperature, the dynamical temperature, the displacement, the stress and the strain distributions have represented graphically using MATLAB.

• 소음진동
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• 제10권2호
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• pp.319-324
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• 2000

This paper shows hot to model the submerged elastic structures and adequate analysis tools for modal behavior when using finite element and boundary element method. Four different cases are reviewed depending on the location of the water and air. First case is that structures are filled with air and water is located outside. Second case is opposite to case one. These cases are solved by direct approach using collocation procedure. Third case is that water is located both sides of structures. Last case is that air is located both sides. These cases are solved by indirect approach using variational procedure. As analysis tools harmonic frequency sweep analysis and eigenvalue iteration method are selected to obtain the natural frequencies of vibrating submerged structures depending on the cases. Results are compared with closed form solutions of submerged spherical shell.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1995년도 추계학술대회 논문집 학회본부
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• pp.195-198
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• 1995

Most of the theorems of nonlinear stability is based on the Lyapunov stability theory. The Lyapunov function method is the most well-known and provides precise and rigorous theoretical backgrounds. However, tile conventional approach to direct stability analysis has been performed without taking account of damping effects. For accurate stability analysis of nonlinear systems, it is required to consider the damping effects. This paper presents a new method to derive a group of Lyapunov functions to reflect the damping effects by considering the integral relationships of the system governing equations. This method tan be utilized as a powerful tool to determine the region of attraction.