• Journal of Korean Society of Coastal and Ocean Engineers
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• v.16 no.3
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• pp.121-129
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• 2004

The different types of coastal souctures have been constructed for the protection of coastal region from the incident waves. Among them. the permeable submerged breakwater has been widely used as a wave dissipater and sediment transport controller because of its excellent advantages in scenery effects, construction efficiency and environment aspects. This study numerically investigated the characteristics of wave energy variations and transmission coefficient at the rear of the permeable submerged breakwater installed in the irregular wave field. To analyze it's performance numerically, a two-dimensional numerical wave flume based on VOF method was used. A frequency spectral analysis showed that the spectral peak moved to the short-period in the one-row submerged breakwater, and the wave energy was distributed evenly for the whole period in the two-row submerged breakwater in the case of breaking on the submerged breakwater. The spectral peak was shown to be converged within the significant wave period at the rear of the permeable submerged breakwater in the case of non-breaking conditions. From the result of transmission coefficients analysis. it was confirmed that a considerable quantity of wave energy was transmitted to the rear of the permeable submerged breakwater in the case of non-breaking rather than breaking.

• Journal of Korean Tunnelling and Underground Space Association
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• v.20 no.2
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• pp.375-392
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• 2018

The shield TBM method is widely adopted for tunneling works in urban area because it has more beneficial ways to control settlement at ground surface than conventional mined tunneling. In the shield tunneling, backfill grouting at tail void is crucial because it is supposed not only to restraint ground deformation around tail void during excavation but also to compensate precedent ground settlement by pushing up the ground with highly pressurized grout. However, the tail void grouting has been found to be ineffective for settlement compensation particularly in sandy ground, which might be caused by complicate interaction between ground and tail void grouting. In this paper, the effects of tail void grouting on behavior of ground in shield TBM tunneling were investigated based on 3-dimensional finite element analyses. The results of numerical analyses indicated that backfill grouting actually reduces settlement by degrading settlement increasing rate in excavation, which means decrease of volume loss. Meanwhile, the grouting could not contribute to compensate the precedent settlement, because reduction of volume loss by grouting was found to be counterbalanced by volume change of ground.

• Journal of Korean Tunnelling and Underground Space Association
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• v.20 no.2
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• pp.527-539
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• 2018

The subway used by many passengers is required to maintain a safe and comfortable environment and PSD (Platform Screen Door) must be installed in the platform after reinforcing the standard in 2003. In the previous research, in case of subway fire to control it, it is necessary to design the optimal ventilation and smoke exhaust system according to equipment capacity of the smoke exhaust system. Therefore, in this study, based on the results of previous research, three-dimensional numerical analysis was performed for the CO gas and smoke flow by the subway ventilation system in case of platform fire. As a result of this study, it was found that in case of emergency, if only the upper-level smoke exhaust system is activated, the risk of evacuation is high due to CO gas (653.8 ppm) and smoke concentration ($768.4mg/m^3$). And when all the smoke exhaust systems are activated and only the fire side PSD is opened, CO gas (36.0 ppm) and smoke concentration ($26.2mg/m^3$) are detected and the propagation range of smoke flow was reduced. When all the smoke exhaust systems are activated and only the fire side PSD is closed, it was analyzed as the most effective ventilation mode in the evacuation environment due to the absence of smoke-recirculation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.12
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• pp.6986-6992
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• 2014

The generalized Voronoi graph (GVG) is a topological map of a constrained environment. This is defined in terms of workspace distance measurements using only sensor-provided information, with a robot having a maximum distance from obstacles, and is the optimum for exploration and obstacle avoidance. This is the safest path for the robot, and is very significant when studying the GVG edges of highly articulated robots. In previous work, the point-GVG edge and Rod-GVG were built with point robot and rod robot using sensor-based control. An attempt was made to use a higher degree of freedom robot to build GVG edges. This paper presents GVG-based a new local roadmap for the two-link robot in the constrained two-dimensional environment. This new local roadmap is called the two-identical-link generalized Voronoi graph (L2-GVG). This is used to explore an unknown planar workspace and build a local roadmap in an unknown configuration space $R^2{\times}T^2$ for a planar two-identical-link robot. The two-identical-link GVG also can be constructed using only sensor-provided information. These results show the more complex properties of two-link-GVG, which are very different from point-GVG and rod-GVG. Furthermore, this approach draws on the experience of other highly articulated robots.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2707-2711
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• 2014

Introduction: Smoking prevalence among the medical students is high in China. Therefore, understanding the smoking motivations of medical students is crucial for smoking control, but currently there are no scales questionnaires customized for probing the smoking motivations of medical students. This aim of study was to test and modify a questionnaire for investigating smoking motivations among medical students. Methods: A cross-sectional survey was conducted among 1,125 medical students at Xuzhou Medical College in China in 2012.The model fit and validity was assessed by confirmatory factor analysis (CFA) and the reliability was tested by single-item reliability, composite reliability, and item-total correlation. Results: The prevalence of smoking was 9.84 % among study population. In the modified scales, the global fit indices identified a CFI value of 0.96, TLI was 0.96, and the RMSEA was 0.063. CFA supported the two dimensional structure of the instrument. The average variance extracted ranged from 0.45 to 0.62. All single-item reliability scores were greater than 0.20, and the composite reliability ranged from 0.74 to 0.91. Conclusion: Modified scales could be the preliminary instrument used in evaluating the smoking motivations of medical students. However, it should be further assessed using other forms and methods of validity and reliability, additional motivations of smoking, and the survey of other medical colleges in China.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.5
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• pp.531-546
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• 2017

Activation of Toll-like receptor-4 (TLR-4) in articular chondrocytes increases the catabolic compartment and leads to matrix degradation during the development of osteoarthritis. In this study, we determined the proteomic and genomic alterations in human chondrocytes during lipopolysaccharide (LPS)-induced inflammation to elucidate the underlying mechanisms and consequences of TLR-4 activation. Human chondrocytes were cultured with LPS for 12, 24, and 36 h to induce TLR-4 activation. The TLR-4-induced inflammatory response was confirmed by real-time PCR analysis of increased interleukin-1 beta ($IL-1{\beta}$), interleukin-6 (IL-6), and tumor necrosis factor alpha ($TNF-{\alpha}$) expression levels. In TLR-4-activated chondrocytes, proteomic changes were determined by two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-mass spectroscopy analysis, and genomic changes were determined by microarray and gene ontology analyses. Proteomics analysis identified 26 proteins with significantly altered expression levels; these proteins were related to the cytoskeleton and oxidative stress responses. Gene ontology analysis indicated that LPS treatment altered specific functional pathways including 'chemotaxis', 'hematopoietic organ development', 'positive regulation of cell proliferation', and 'regulation of cytokine biosynthetic process'. Nine of the 26 identified proteins displayed the same increased expression patterns in both proteomics and genomics analyses. Western blot analysis confirmed the LPS-induced increases in expression levels of lamin A/C and annexins 4/5/6. In conclusion, this study identified the time-dependent genomic, proteomic, and functional pathway alterations that occur in chondrocytes during LPS-induced TLR-4 activation. These results provide valuable new insights into the underlying mechanisms that control the development and progression of osteoarthritis.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.1
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• pp.107-114
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• 2017

A turbocharger is an engine supercharger that is driven by exhaust gas. It improves the output and fuel efficiency by increasing the charging efficiency of the mixture gas, which is achieved by changing the rotatory power of the turbine connected to the exhaust passage. It is important to control the supercharging for this purpose. A nozzle slide joint is one of the core parts. Austenitic stainless steel is currently used as the material for this part, and its excellent mechanical properties include high heat resistance and corrosion resistance. However, because of its poor machinability, there are many difficulties in producing products with complicated shapes. Machining is used in the production of nozzle slide joints for high dimensional accuracy after metal powder injection molding. As design variables in this study, we investigated the sintering temperature, product stress, deformation rate, radius of curvature of the punch, and angle of the chamfer punch, which are related to the strain and shapes. The goal is to suggest a forming process using Nitronic 60 that does not require machining to manufacture a nozzle slide joint for a turbocharger. Accordingly, we determined the best process environment using finite-element analysis, the signal-noise ratio, and the Taguchi method for experiment design. The relative density and hydrostatic pressure of the final product were in accordance with the results of the finite element analysis. Therefore, we conclude that the Taguchi method can be applied to the design process of metal powder injection molding.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.11
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• pp.740-745
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• 2016

Cables are installed for tens of thousands of connections between various pieces of equipment to operate and control a commercial ship. The correct shortest-route data is necessary since these are complicated cable installations. Therefore, an overfill interval commonly exists in the shortest paths for cables as estimated by Dijkstra's algorithm, even if this algorithm is generally used. It is difficult for an electrical engineer to find the overfill interval in 3D cable models because the occupancy rate data exist in a data sheet unlinked to three-dimensional (3D) computer-aided design (CAD). The purpose of this study is to suggest a visualization method that displays the cable path and overfill interval in 3D CAD. This method also provides various color visualizations for different overfill ranges to easily determine the overfill interval. This method can reduce cable-installation man-hours from 7,000 to 5,600 thanks to a decreased re-installation rate, because the cable length calculation's accuracy is raised through fast and accurate reviews based on 3D cable visualization. As a result, material costs can also be reduced.

• Radiation Oncology Journal
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• v.32 no.3
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• pp.187-197
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• 2014

Purpose: We aimed to analyze the treatment outcome and long-term toxicity of 70 Gy hypofractionated intensity-modulated radiotherapy (IMRT) for localized prostate cancer using a customized rectal balloon. Materials and Methods: We reviewed medical records of 86 prostate cancer patients who received curative radiotherapy between January 2004 and December 2011 at our institution. Patients were designated as low (12.8%), intermediate (20.9%), or high risk (66.3%). Thirty patients received a total dose of 70 Gy in 28 fractions over 5 weeks via IMRT (the Hypo-IMRT group); 56 received 70.2 Gy in 39 fractions over 7 weeks via 3-dimensional conformal radiotherapy (the CF-3DRT group, which served as a reference for comparison). A customized rectal balloon was placed in Hypo-IMRT group throughout the entire radiotherapy course. Androgen deprivation therapy was administered to 47 patients (Hypo-IMRT group, 17; CF-3DRT group, 30). Late genitourinary (GU) and gastrointestinal (GI) toxicity were evaluated according to the Radiation Therapy Oncology Group criteria. Results: The median follow-up period was 74.4 months (range, 18.8 to 125.9 months). The 5-year actuarial biochemical relapse-free survival rates for low-, intermediate-, and high-risk patients were 100%, 100%, and 88.5%, respectively, for the Hypo-IMRT group and 80%, 77.8%, and 63.6%, respectively, for the CF-3DRT group (p < 0.046). No patient presented with acute or late GU toxicity ${\geq}$grade 3. Late grade 3 GI toxicity occurred in 2 patients (3.6%) in the CF-3DRT group and 1 patient (3.3%) in the Hypo-IMRT group. Conclusion: Hypo-IMRT with a customized rectal balloon resulted in excellent biochemical control rates with minimal toxicity in localized prostate cancer patients.

• Journal of Korea Water Resources Association
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• v.53 no.4
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• pp.313-322
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• 2020

There is always a risk of water disasters due to sudden storms in mountainous regions in Korea, which is more than 70% of the country's land. In this study, a radar-based risk prediction technique for sudden downpour is applied in the mountainous region and is evaluated for its applicability using Mt. Biseul rain radar. Eight local heavy rain events in mountain regions are selected and the information was calculated such as early detection of cumulonimbus convective cells, automatic detection of convective cells, and risk index of detected convective cells using the three-dimensional radar reflectivity, rainfall intensity, and doppler wind speed. As a result, it was possible to confirm the initial detection timing and location of convective cells that may develop as a localized heavy rain, and the magnitude and location of the risk determined according to whether or not vortices were generated. In particular, it was confirmed that the ground rain gauge network has limitations in detecting heavy rains that develop locally in a narrow area. Besides, it is possible to secure a time of at least 10 minutes to a maximum of 65 minutes until the maximum rainfall intensity occurs at the time of obtaining the risk information. Therefore, it would be useful as information to prevent flash flooding disaster and marooned accidents caused by heavy rain in the mountainous area using this technique.