• 생명과학회지
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• 제9권6호
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• pp.692-697
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• 1999

주정폐액과 같은 고 농도의 유기성 폐액의 효율적 처리에는 혐기적, 호기적인 생물학적인 처리와, 생물학적으로 난분해성 물질의 화학적 처리가 요구되었다. 난분해성 COD성분을 제거하기 위하여 Fenton처리 전에 가능한 많은 유기물의 제거가 요구되며, 이때 $FeCl_3$,alum,cationic polymer의 처리가 효과적이었다. 이 처리과정 중은 몰론 Fenton 처리과정 중에 생성되는 슬러지의 제거 효율에 따라 전체 폐수처리효율리 크게 영향을 받게되 슬러지의 효과적인 제거과정이 필요하였다, 이를 위해 기포의 직경이 80-120 um 정도되는 기존의 DAF방식에 비해 새로 도입한 PBF법에 의해 생성되는 직경 20-50um 의 미세포기는 슬러지의 부상을 촉진시켜 화학적 슬러지의 제거 효율이 훨씬 뛰어남을 알 수 있었다. 이에 따라 PBF법에 의한 슬러지의 제거는 기존의 DAF법에 비해 약품 사용량, 용수의 절감, 방류량의 감소 등으로 전체 운전비용을 약 30%정도 줄일 수 있었다.

• Nuclear Engineering and Technology
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• 제9권4호
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• pp.203-210
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• 1977

디메틸썰폭사이드를 표지보조제로 사용하여 방사면역측정용 $^{125}$/I 표지인슈린을 효과적으로 만들 수 있었다. 디메틸썰폭사이드 조금을 통상의 표지반응 혼합물에 첨가하여 반응시간을 조절하여 보았더니 표지반응속도는 약간 느렸으나 이렇게 하여 얻은 표지인슈린은 항체와의 결합능이 좋았으며 표준곡선을 점시했을 때 큰 구배를 보였다. 표지반응수율도 반응시간을 1분으로 늘림에 따라 약 30%로 늘어났다. 평균 항체결합능(B/F)의 증가는 일정항체 희석비율하에서 표지보조제없이 표지한 인슈린을 쓴 때가 1.5인데 반해 표지보조제를 쓴 경우는 2.5로서 약 70%의 향상을 보였다. 핵자기공명분광법으로 표지혼합물에 첨가한 디메틸썰폭사이드는 클로라민티에 의해 디메틸썰폰으로 산화된다는 것을 확인하였다. Stagg등의 결과와 대략 같은 이 실험결과를 디메틸썰폭사이드와 인슈린분자 중의 유황결합이 클로라민티에 의해 경쟁적 산화를 받는 것으로 보고 이를 토의하였다.

• Parasites, Hosts and Diseases
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• 제22권2호
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• pp.161-171
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• 1984

An epidemiological study on Metagenimus yokegawai infection was performed in Samcheok-Bun, Kangwon Province during the period from November 1983 to October 1984. Formalin-ether concentration technique and Stoll's dilution egg counting method were employed to figure out the prevalence and infection intensity of M. yrtkogawai infection. The results are summarized as follow: 1. The Prevalence of M. yokogawai infection was 13.3% among 1,172 examined; 18.0% (114 out of 632) in male and 7.8% (42 out of 540) in female. 2. The Prevalence rates were different by stream; 15.5% in Ohsip-chon (stream), 11.8% in Maeup-chon and 1.6% in Gagok-chon. 3. Along the basin of Oship-chon; 8.2% at the lower reaches in Samcheok-eup, 25.9% at the middle reaches in Miro-myon and 6.2% at the upper reaches in Dogeoe-eup, respectively. 4. By age group, the highest fate (18.3∼20.2%) was observed in 30∼49 years of age (male 24.1∼28.7%, female 11.2∼13.2%). 5. By social strata, the positive rate was 15.0% (120 out of 799) in general inhabitants and 9.7% (36 out of 373) in school children. 6. Intensity by EPG count in feces was 419 in average; the light infection (less than 400 EPG) was 70.4%, moderate infection (401∼1,000 EPG) 19.4% and heavy infection (more than 1,001 EPG) 10.25 respectively. 7. All the 67 sweetfish (length 10.3∼18.5cm) which were caught from Ohsip-stream were infected with metacercariae of M. yokogawai and the number of metacercariae detected were 382 per fish in average (323 in June and 382 in September). 8. Experiences of intake of raw fresh-water fish [Plecoglossus altivelis and Leuciscus (Tribolodon〕 were present in 50.3U (354 out of 704) of the inhabitants along Ohsip-stream according to questionnaire study. The results of this survey indicated that the middle reaches of Ohsip-stream in Miro-myon, Samcheok-gun is the endemic region for M. yokogawai infection.

• 대한소아치과학회지
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• 제11권1호
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• pp.75-89
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• 1984

A total of 141 strains of Streptococcus mutans were isolated from dental plaques of 153 subjects. Eighty-two children with caries-experience, 18 caries-free children and their mothers were participated. All isolates were examined for their serotypes by immunodiffusion method with 7 reference sera and their antibiotic susceptibilities to 7 antibiotics by agar dilution method using 7 kinds of antibiotics, and were compared their results by caries experience (DMFT ratio) and by intrafamilial levels. 1. Isolation rate of Streptococcus mutans were greater in samples of carious teeth than those of sound teeth, and in mothers than in children. 2. Multiple serotypes of Streptococcus mutans were occasionally found in a single samples. 3. Of the total 141 isolates (83 isolates from children, and 58 from their mothers), type c isolates were most prevalent (63.8%). Type d,e and f were found, comprizing 14.9%, 10.6% and 6.4% respectively. Serotype g, a and untypable strain were also found but far lower frequencies (2.8-0.7%), and type b was detected. 4. These results suggest that there are no significant correlation among the distribution of serotypes, antibiotic susceptibilities, caries experience and intrafamilial relationships. 5. Most of isolates were susceptible to chloramphenicol (100%), penicillin (95.7%), ampicillin (94.3%), and gentamicin (92.2%), but about one-third isolates were resistant to cephaloridine (27%), streptomycin (33.3%) and kanamycin (47.6%), resulting that 91 strains (64.5%) among 141 isolates were resistant to one or more drugs used. 6. Of the 91 resistant strains, 20 different resistant patterns were observed, and the most frequently encountered patterns were KM, SM and CE.

• Asian-Australasian Journal of Animal Sciences
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• 제23권10호
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• pp.1333-1339
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• 2010

The present study was conducted to determine plasma acetate, glucose and protein metabolism using dilution of isotopes [[1-$^{13}C$]Na acetate, [U-$^{13}C$]glucose and [1-$^{13}C$]leucine (Leu)] in sheep fed rice straw (Oriza japonica L.). Four sheep were assigned to either rice straw (RS-diet) or mixed hay (MH-diet) with a crossover design. Nitrogen (N) intake and N digestibility were lower (p = 0.002 and p = 0.02, respectively) for RS-diet than MH-diet, but N retention did not differ (p>0.10) between the diets. Concentrations of rumen acetate tended to be lower (p = 0.07), and propionate was higher (p = 0.02) for RS-diet than MH-diet. Concentrations of plasma lactate, non-esterified fatty acids, Leu and ${\alpha}$-ketoisocaproic acid did not differ (p>0.10) between the diets, but plasma glucose and urea concentrations were lower (p = 0.01 and p = 0.003, respectively) for RS-diet than MH-diet. Turnover rate of plasma acetate did not differ (p = 0.39) between the diets, and plasma glucose and Leu turnover rates were numerically lower (p = 0.15 and p = 0.14, respectively) for RS-diet than MH-diet. Whole body protein synthesis and degradation did not differ (p>0.10) between the diets. Thus it can be concluded that the intermediary metabolism of acetate, glucose and protein on rice straw is comparable to mixed hay in sheep.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4843-4846
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• 2013

Background: The infusion rate is considered to affect incidence and severity of infusion reactions (IRs) caused by protein formulations. Trastuzumab (TRS) is approved for 90-minute infusion as the initial dose followed by 30-minute infusion with 250 ml saline. In the study, we evaluated the safety of TRS intravenously administered over 30 minutes with 100 ml saline to reduce burden of patients, safety of infusion with 250 ml saline already being established. Materials and Methods: Women with HER2 positive breast cancer, ${\geq}18$ years and ${\geq}55%$ left ventricular ejection fraction (LVEF), were registered in the study. Patients received 8mg/kg of TRS 250 ml over 90 minutes followed by 6mg/kg of TRS 100ml over 30 minutes in a three-week cycle. Results: A total of 31 patients were recruited, 24 for adjuvant therapy and seven with metastases. The median age was 59 years (range 39 to 82). The total number of TRS doses ranged from 5 to 17 with the median of 15. Mild IR occurred in two patients at the first dose. However, no IR was observed after reducing to 100 ml saline. No decrease of LVEF, increase of serum brain natriuretic peptide or any other adverse events were reported. Conclusions: Intravenous infusion of TRS with 100 ml saline over 30 minutes in breast cancer patients can be considered safe based on results from the study. It can be given on an outpatient basis as with the currently recommended dilution in 250 ml saline.

• Asian-Australasian Journal of Animal Sciences
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• 제12권6호
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• pp.886-890
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• 1999

From previous studies, there is a strong possibility in buffaloes that the marked increase in blood volume (BV) under hot conditions contributes to heat transportation from the rectum to the skin. The present study was done to clarify changes with environmental temperature on water-shift between blood and extracellular fluid (ECF), heat distribution between the rectum and the skin, and blood flow rates (BFR) at the hind legs (reflecting the skin surface). Four buffaloes and four Friesian cows were successively exposed to three different temperatures of $20^{\circ}C$, $30^{\circ}C$ and $35^{\circ}C$. BV and ECF volume were measured with Evans' blue and sodium-thiocyanate dilution methods, respectively. Rectal and subcutaneous (as the skin) temperatures were measured by copper-constantan thermocouples. BFR were measured by a supersonic blood flow meter. With an increase in environmental temperature, skin temperature in buffaloes increased significantly than cows, but rectal temperature was not significantly different between two species. BV, especially plasma compartment, increased significantly in only buffaloes, while ECF volume did not change in both species. BFR increased significantly in buffaloes, but not in cows. From these results, the increased of BV may be caused by water flowing from ECF compartment. The water-shift may induce the increase of BFR and skin temperature. It is suggested in the present study that internal changes of blood compartment in buffaloes contribute to transfer of heat to the skin surface.

• KSBB Journal
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• 제19권3호
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• pp.236-240
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• 2004

Batch experiment에서 다양한 질소 농도에서 구해진 질소제거 속도와 비 생장속도 등의 데이터를 토대로 4.6일의 체류시간을 갖는 2단 처리 장치를 설계하였다. 그리고 continuous experiments에서는 3.5일의 체류시간을 갖는 2단의 처리 장치를 설계하였다. 두 가지 값에 차이는 있지만 실제 현장에서 폐수 처리 장치를 설계할 때 충분한 자료가 되리라고 판단한다. 따라서 위의 결과를 토대로 기존 시스템에 미세조류 시스템을 부가한다면 기존공정의 단점인 잉여질소 제거 장치로서 충분히 역할을 수행해 배출 기준치를 만족시키는 안전한 폐수처리장치가 되리라고 판단한다.

• 한국해안·해양공학회논문집
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• 제23권6호
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• pp.466-473
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• 2011

온배수의 수중 방류 시 강한 방류 모멘텀 플럭스와 부력 플럭스에 의해 수중제트 인근에는 부력제트가 지배적인 근역이 형성되며, 이러한 근역을 해석하는 도구로써 비정수압 RANS 방정식을 적용한 전산유체역학(CFD) 모델을 이용하여 근역에 대한 적용성을 검토해 보았다. 과거 연구된 바 있는 원형 부력제트 수리실험과 유사한 조건으로 모델을 구성하고 정류시의 수평 부력 제트 경우와 가로흐름시 수직 부력 제트 경우에 대해 수치 실험을 수행하였다. CFD 수치실험의 결과는 수리실험 및 해석해 모델(CorJET)의 결과와 무차원화한 중심 궤적 및 희석율에 대해 비교 검증하였는데, 실제 수리실험의 결과와 잘 일치하는 것으로 나타났다. CFD 모델은 현재 근역 해석해 모델과 광역 준3차원 해수유동 모델이 가지고 있는 한계를 모두 보완할 수 있어 수중방류 온배수 영향해석에 적합한 모델이며, 본 연구를 통해 근역해석의 적합성을 확인하였으므로 향후 계산효율이 확보된다면 수중방류 온배수의 이동 및 확산 해석 도구로써 널리 활용될 것으로 기대된다.

• Asian-Australasian Journal of Animal Sciences
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• 제19권12호
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• pp.1716-1721
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• 2006

The present study was conducted to observe the effect of osmolality of glycerolated TEST-yolk glycerol extenders on post-thawing sperm kinematics of ram spermatozoa of the native Malpura breed maintained in a semi-arid tropical environment. Good quality semen obtained from adult rams was pooled, split and diluted to 1,000 million spermatozoa per ml in complete TEST-yolk-glycerol extenders of 900, 1,200, 1,500 and 1,800 mOsm/kg osmolality. Diluted semen samples were loaded in 0.25 ml straws and cooled down to $-125^{\circ}C$ freezing temperature at the rate of $-25^{\circ}C$ per minute under controlled conditions before plunging into liquid nitrogen for storage. The thawing of straws was performed at $50^{\circ}C$ in a water bath for 10 seconds and sperm kinematics of the frozen-thawed spermatozoa were assessed by a computer-assisted sperm analysis technique. Osmolality of diluent had no significant effect on post-thawing % motility, % rapid, % medium and % slow moving frozen-thawed spermatozoa but significantly (p< 0.05) affected the % linearity and % straightness. The post-thawing % motility and % rapid motile spermatozoa were highest in samples extended in diluent of 1,500 mOsm/kg osmolality and lowest in 900 mOsm/kg. The curvilinear velocity of spermatozoa was significantly (p<0.05) higher for samples extended in 1,800 mOsm/kg, compared to those in 900 and 1,200 mOsm/kg, but the effect was not significantly different to those extended in diluent of 1,500 mOsm/kg osmolality. The study indicated that ram spermatozoa could tolerate a wide osmolality range for dilution in the complete TEST-yolk-glycerol extender for their cryosurvival. The highest recovery of motile spermatozoa following thawing was achieved in samples extended in the TEST-yolk-glycerol diluent of 1,500 mOsm/kg osmolality.