• The Journal of Engineering Geology
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• v.31 no.1
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• pp.55-66
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• 2021

Hydraulic-mechanical (H-M) coupled numerical modeling was used to evaluate the evolution of hydrogeological properties in response to the installation and expansion of a borehole. A domain with a discrete fracture network was adopted for discontinuum modeling to simulate changes in fracture apertures. Comparison with real hydraulic test data shows that the effects of principal stress direction and expansion of borehole diameter were reasonably simulated by H-M coupled numerical modeling. The modeling confirmed that aperture changes depended on the principal stress direction, with an increase in aperture size due to vertical displacement being the dominant effect. A concentration of shear dilation around the borehole had an additional, subsidiary, effect on the hydrogeological evolution. These results show that the permeability of fractured rock can be increased by changing the hydraulic properties of a fracture through stress redistribution caused by the installation and expansion of a borehole.

• Journal of the Korean GEO-environmental Society
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• v.12 no.11
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• pp.23-30
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• 2011

In this study, Terzaghi's formula was modified to solve problems considering the dilatancy effect of the soil for estimating the earth pressure acting on tunnel. It is performed for the comparison with Terzaghi's formula and modified Terzaghi's formula, tunnel model test result of Kobe University Rock Mechanics Laboratory. From comparison results of the earth pressure acting on tunnel, the earth pressure calculated by the Terzaghi's formula was estimated largest value. The earth pressure measured through the tunnel model test was least value. The difference between the earth pressure derived from Terzaghi's original formula and that derived from the modified formula was caused by the dilation effect, which was caused by the soil volume change. The difference between the earth pressure derived from the modified formula and the earth pressure measured through the tunnel model test, earth pressure results from the energy making failure surface. The results of FEM analysis were almost consistent with the results of mathematical analysis.

• Exercise Science
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• v.26 no.1
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• pp.61-68
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• 2017

PURPOSE: To examine the cumulative (7 days) effect of breaking up prolonged sitting on systemic endothelial function in sedentary men. METHODS: Thirty sedentary men ($33.93{\pm}5.72years$) participated in two randomized 7 days sitting trial (Sit group (control) vs. Breaks group). The protocol of Breaks group is as follows: 4-minute of moderate-intensity marching in place (walking) every 1 hour during business hour (total: 8 breaks/day). Assessment of brachial artery endothelial function using flow-mediated dilation (FMD) and arterial stiffness indices (augmentation index, arterial pressure and pulse wave velocity) were measured before and after 7 days treatment. RESULTS: Brachial artery FMD significantly increased after 7 days breaking up prolonged sitting treatment (Breaks groups, $9.65{\pm}2.61$ to $9.62{\pm}2.6%$) compared with 7 days prolonged sitting (Sit group, $8.37{\pm}3.41$ to $10.11{\pm}3.75%$) (interaction effect, p=.004). Arterial pressure (AP) significantly increased after treatment (Breaks group, $2.75{\pm}2.19$ to $2.38{\pm}1.63mmHg$, p=.002) in Sit group but there was no change (Sit group, $1.00{\pm}3.18$ to $2.50{\pm}9.23mmHg$) in Breaks groups (interaction effect, p=.008). CONCLUSIONS: These finding show that 7 days regular breaking up prolonged sitting improve in FMD, compared with prolonged sitting. Therefore, regular breaking up prolonged sitting may improve systemic endothelial function in sedentary men.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.34 no.6
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• pp.385-392
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• 2021

Interest in the seismic performance of nuclear facilities under strong earthquakes has increased because their nonlinear response is important. In this paper, we proposed appropriate parameters for the nonlinear finite element analysis of a concrete material model, for a reinforced concrete (RC) shear wall in nuclear facilities: maximum tensile strength, dilation angle, and damage parameter. The study of the effects of the important parameters, on the nonlinear behavior and shear failure mode of the RC shear wall having low aspect ratio, was conducted using ABAQUS finite element analysis program. Based on the study results the nonlinear response of a nuclear reactor containment building (RCB) subjected to a strong earthquake was evaluated using nonlinear time-history analysis.

• BMB Reports
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• v.55 no.4
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• pp.181-186
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• 2022

Ventriculomegaly induced by the abnormal accumulation of cerebrospinal fluid (CSF) leads to hydrocephalus, which is accompanied by neuroinflammation and mitochondrial oxidative stress. The mitochondrial stress activates mitochondrial unfolded protein response (UPRmt), which is essential for mitochondrial protein homeostasis. However, the association of inflammatory response and UPRmt in the pathogenesis of hydrocephalus is still unclear. To assess their relevance in the pathogenesis of hydrocephalus, we established a kaolin-induced hydrocephalus model in 8-week-old male C57BL/6J mice and evaluated it over time. We found that kaolin-injected mice showed prominent ventricular dilation, motor behavior defects at the 3-day, followed by the activation of microglia and UPRmt in the motor cortex at the 5-day. In addition, PARP-1/NF-κB signaling and apoptotic cell death appeared at the 5-day. Taken together, our findings demonstrate that activation of microglia and UPRmt occurs after hydrocephalic ventricular expansion and behavioral abnormalities which could be lead to apoptotic neuronal cell death, providing a new perspective on the pathogenic mechanism of hydrocephalus.

• Korean Journal of Clinical Laboratory Science
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• v.54 no.4
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• pp.307-315
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• 2022

Since attaining middle age, many patients suffer from the post-micturition dribble (PMD) syndrome but do not receive proper treatment. This is because the etiology and treatment mechanisms of PMD differ from conventional lower urinary tract symptoms. Several pathophysiologies have been proposed, but the mechanisms we observed are the weakening of the bulbocavernosus muscle and dilation of the urethra due to atrophy of the cavernosal tissue. This study investigates the mechanism of PMD by observing anatomical changes in the corpus cavernosum and urethra. SD male rats were categorized by age into the young rats group (8 weeks old) and the old rats group (24 months or more). The ratio area of the bulbous urethra and corpus cavernosum to the total penis was statistically significant between both groups (P<0.05). Significant differences were obtained between the two groups for restored smooth muscle contents and several other parameters related to PMD mechanisms (nNOS, α-SMA) (P<0.05). The changes in size and parameters of the urethra and corpus cavernosum in young and old rats were confirmed. The results from this study are expected to contribute to the study of PMD in the future.

• Journal of the Korean Geotechnical Society
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• v.25 no.4
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• pp.39-54
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• 2009

Large scale direct shear tests were carried out to analyze the shear behavior of crushed rocks at local representative quarries. Shear strength for each specimen was derived and the effects on shear behavior induced by the variation of factors such as particle size, water immersion, density, uniformity coefficient, and particle breakage were evaluated and quantitatively compared with previous studies. The opportunity was also taken to identify stress-dilatancy relation of crushed rocks following the energy-based theory and friction coefficients at critical state as well as peak friction angles and dilation angles were estimated. As a result of tests it was found that uniaxial compressive strength and particle breakage of the parent rocks have crucial effect on internal friction angles; in addition, dilatancy at the failure showed strong relationship as well.

• Journal of the Korean Geotechnical Society
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• v.22 no.10
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• pp.173-181
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• 2006

A Two Mobilized-Plane Model is proposed for monotonic and cyclic soil response including liquefaction. This model is based on two mobilized planes: a plane of maximum shear stress, which rotates, and a horizontal plane which is spatially fixed. By controlling two mobilized planes, the model can simulate the principal stress rotation effect associated with simple shear from different $K_0$ states. The proposed model gives a similar skeleton behaviour for soils having the same mean stress, regardless of $K_0$ conditions as observed in laboratory tests. The soil skeleton behaviour observed in cyclic drained simple shear tests, including compaction during unloading and dilation at large strain is captured in the model. Undrained monotonic and cyclic response is predicted by imposing the volumetric constraint of the water on the drained or skeleton behaviour. This constitutive model is incorporated into the dynamic coupled stress-flow finite difference program of FLAC (Fast Lagrangian Analysis of Continua). The model was first calibrated with drained simple shear tests on Fraser River sand, and verified by comparing predicted and measured undrained behaviour of Fraser River sand using the same input parameters.

• Journal of English Language & Literature
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• v.56 no.5
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• pp.797-821
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• 2010

This paper aims to explore how Millay's love sonnets rewrite the carpe diem tradition in the complicated ways. This paper redirects critical attention away from Millay's individual experience and inner self toward the scene of literary history, suggesting that there may be more historical consciousness in Millay's sentimental and feminine "gesture." Rewriting the carpe diem tradition, Millay's sonnets reveal an awareness of the dependence of the carpe diem poems' discursive logic on the woman's coyness, its inability to accomplish its triumph over woman or time (death) without her posited reluctance. Contrary to Andrew Marvel's "To His Coy Mistress," the speakers of Millay's sonnets could never be accused of the sexual coyness; they are outspoken in their defiance of both death and lovers whose possessiveness resembles death's embrace. Moreover, as Stacy Carson Hubbard points out, by converting female sexual experience from its status as a onetime closural event to repeatable one, hence an opportunity for the general and emotional irritability productive of narrative, Millay seizes for the woman the power of "dilation" in both its sexual and its verbal forms. Furthermore, this paper argues that the woman's sex no longer invites analogies to things secret and sealed, preserved or ruined in Millay's sonnets. The woman's promiscuity implies a rejection of monumentalizing love, as well as a refusal of the fixing inherent in the carpe diem's fearful invocation of the movement of time. Throughout the love sonnets, the speaker's sexualized body produces nothing but ephemera. For Millay, this body spends its powers in hopes of having them, and the force of this spending is a perpetual and willful forgetting, which makes possible the repetition of love's story. Ultimately, Milly disturbs our critical categories by rendering permeable boundaries between modern literature and dead form of classic literature, the female speaker and male speaker.

• Computers and Concrete
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• v.32 no.5
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• pp.465-474
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• 2023

The point load test (PLT) is a widely-used alternative method in the field to determine the uniaxial compressive strength due to its simple testing machine and procedure. The point load test index can estimate the uniaxial compressive strength through conversion factors based on the rock types. However, the mechanism correlating these two parameters and the influence of the mechanical properties on PLT results are still not well understood. This study proposed a theoretical model to understand the mechanism of PLT serving as an alternative to the UCS test based on laboratory observation and literature survey. This model found that the point load test is a self-confined compression test. There is a compressive ellipsoid near the loading axis, whose dilation forms a tensile ring that provides confinement on this ellipsoid. The peak load of a point load test is linearly positive correlated to the tensile strength and negatively correlated to the Poisson ratio. The model was then verified using numerical and experimental approaches. In numerical verification, the PLT discs were simulated using flat-joint BPM of PFC3D to model the force distribution, crack propagation and BPM properties' effect with calibrated micro-parameters from laboratory UCS test and point load test of Berea sandstones. It further verified the mechanism experimentally by conducting a uniaxial compressive test, Brazilian test, and point load test on four different rocks. The findings from this study can explain the mechanism and improve the understanding of point load in determining uniaxial compressive strength.