• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.1
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• pp.165-170
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• 2007

Pyungwi-san(PWS) have been using as a basic prescription of digestive disorder in Korean traditional medicine. This study was performed to examine the in vitro antioxidant activity of the extract using different antioxidant tests including by 1,1-diphenyl-2-picryl-hydrazil (DPPH) radical scavenging, superoxide anion radical scavenging, metal chelating hydrogen peroxide scavenging, lipid peroxydation protective effect and scavenging effect of nitric oxide and peroxynitrite. Herbal-acupuncture solution of PWS(PWS-HS) exhibited a concentration-dependent inhibition of DPPH radical adduct formation and it showed dose-dependent free radical scavenging activity onto superoxide anions. In addition, the result of metal chelating hydrogen peroxide scavenging and ammonium thiocyanate experiments showed that PWS-HS was an active scavenger of hydroxyl radicals. Furthermore, it was also found to be effective in scavenging nitric oxide and peroxynitrite, well-known cytotoxic species that can oxidize several cellular components such as proteins, lipids and DNA.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.4
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• pp.57-66
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• 2010

Purpose: To provide basic informations for guidelines of Ginseng usage during lactation. Method: Based on a regulation of scope and preparation of herbal prescriptions by Ministry of health and welfare of Korea, we selected the formulae for postpartum care and disease in 7 Korean Medical Classics. And we searched the number of formulae including Ginseng, dosage and indications of Ginseng in formulae in those books. Results: The range of Ginseng dosage during lactation from medical classics is 1.5-18.75g/day for medical purposes. Indications of Ginseng are lethargy, excessive bleeding, asthma, fever, cold, pain, dizziness, mental disorder, spasm, digestive problem, constipation, diarrhea, urinary incontinence, edema, breast engorgement, lack of breastmilk, breast ulcer, etc. But Ginseng had not been used in the case of stroke, epistaxis, beginning of mastitis, tumor of lower abdomen. Conclusions: Ginseng should be recommended less than 1.5g/d as a nutritional supplement. If breastfeeding woman wants to take Ginseng as a medication or as a tonic, she should consult with a official specialist about proper prescription and dosage instead of risky random medication.

• Herbal Formula Science
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• v.21 no.1
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• pp.1-15
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• 2013

Objectives : This article is a study on to which categories of modern diseases blood stasis patterns are assigned and the meaning of blood stasis interpreted with perspectives of Korean Medicine and modern medicine. Methods : We reviewed "Neijing", "Shanghanlun", "Yilingaicuo", "Xuezhenglun" and other books and modern clinical papers related with blood stasis. Results : 1. Blood stasis patterns are related with disorders of hemorrheology, hemodynamics, platelet function, microcirculation, microelements and endothelial damage. 2. From the types of syndrome differentiation, diverse diseases classified in type of qi deficiency with blood stasis and type of blood stasis due to qi stagnation are reported, which reflects qi and blood are closely connected. And many diseases are classified in type of kidney deficiency with blood stasis, which has something in common with chronic diseases can achieve effect from treatment considering blood stasis. 3. Diseases related with kidney involve menopausal disorder, mazoplasia, prostatitis, erectile dysfunction, chronic nephritis, renal calculus, osteoporosis and bursitis. Diseases related with heart involve coronary artery disease, arrhythmia and cerebral thrombosis. Diseases related with spleen involve gastritis, colonitis and digestive organ ulcer. Diseases related with liver involve hepatitis, hyperthyroidism and stroke. Diseases related with lung involve neurodermatitis, bronchitis and paranasal sinusitis. Conclusions : Blood stasis pattern which is one of the areas to draw medicine's attention has broad clinical application.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3605-3616
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• 2015

Cancer is basically a class of disorder marked by uncontrolled proliferation of cells which have the potential to interfere with different systems of body like digestive, central nervous and circulatory systems by releasing hormones. Tumors that reside only in a specified location and show restricted growth are commonly characterized as benign tumors. When tumor cells grow and effectively spread to other body parts and potentially invade and damage healthy tissues they show various degrees of malignancy. Cancer may be caused by different factors like gene mutations, carcinogens and some medical factors that harm the immune system of the body. Symptoms of cancer are relatively varied and classified according to location, progression pattern and size of tumors as well. Different diagnostic tests are used for evaluation that depends on the type of cancer. Cancer management and chemo protocols also depend on the progression and site where it develops. Cancers like breast, lung, liver, colorectal, prostate, head and neck carcinoma are most commonly diagnosed in Pakistan. This review briefly describes the three most common cancers prevailing in Pakistan and their management evaluation.

• Korean Journal of Pharmacognosy
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• v.21 no.4
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• pp.300-306
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• 1990

Chichul-Tang, a combined preparation of crude drug, which was composed of Atractylodis Rhizoma alba and Ponciri Fructus, has been used widely for digestive disorder. Each herb extract of Atractylodis Rhizoma and Ponciri Fructus, the mixture of both herb extracts were examined for the effects on isolated smooth muscle, intestinal propulsion, anti-cathartic action and gastric secretion. The results were summarized as follows: Chichul-Tang showed the inhibitory effects of the convulsion of smooth muscle. Anti-cathartic effect was shown and gastric secretion was inhibited.

• Journal of Society of Preventive Korean Medicine
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• v.17 no.1
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• pp.51-63
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• 2013

Objectives : This study aimed to investigate the current situation of Internet health counseling in Korean Medicine by analyzing the contents and pattern of the questions and answers in NAVER Jisik-iN. Methods : 1,121 questions answered by Korean Medicine doctors in NAVER Jisik-iN from January 2012 to June 2012 were extracted and analyzed. The contents and pattern of the questions and answers were classified. Then statistical analysis was performed and the research findings were compared with other studies. Results : Korean Medicine (KM) accounted for 1.73 percent of health counseling in NAVER Jisik-iN. Analyzing the questions and answers of KM counseling, questions about symptoms and answers providing medical knowledge were most common. The most frequently asked symptom was digestive disorder. Applying to Suchman's "Stage of Illness and Medical Care" model, 'the symptom-experience' stage took the first place. Conclusions : KM counseling in NAVER Jisik-iN has served as guidance for potential Korean Medicine consumers by providing medical knowledge about symptoms. For more effective guidance there should be a systematic Internet counseling system offering reliable information by KM doctors to meet the needs of medical consumers.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.1
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• pp.252-255
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• 2008

Phlegm-retention disease, which is called dameum(痰飮), is a kind of a pathologic secretion products, accumulated excessive water in a special part of a body. Urticaria is a common dermatopathy, coming under “eun-jin(隱疹)” in Korean herbal medicine. Headache and vertigo is a very common diseases in life. There are so many causes which induce uticaria, headache and vertigo. We experienced 31-year old woman case suffering from chronic urticaria, headache, vertigo with digestive disorder, nausea. We diagnosed those symptoms as dameum(痰飮). So we administered Jeongjeongamiyijintang-gamibang(正傳加味二陳湯加味方) to the urticaria, and Banhabaekchulcheonma-tang (半夏白朮天麻湯) to the headache, vertigo. They are both famous herbal medicines for treating dameum-related symptoms, because both of them contains Yijin-tang(二陳湯) which is the main Herbal medicine for dameum(痰飮). We suggest that dameun-related urticaria, headache, vertigo can be treated by preceding medicines.

• YAKHAK HOEJI
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• v.37 no.2
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• pp.172-181
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• 1993

The purpose of this study was to evaluate the clinical efficacy and safety of NRM which was newly developed as a combination product containing antacids, digestive enzyme and herbal drugs, and OTA powder, called OHTA'S ISAN on the morret, for the treatment of various symptoms in upper gastrointestinal diseases. 63 patients were recruited, 36 as a treated group with NRM and 27 as a controlled one with OTA. Patients were randomly allocated to receive either NRM or OTA t.i.d. for treatment of upper G-1 symptoms and undergone endoscopic, symptomatic and clinical laboratory assessments before and after 2 weeks. The results were as follows; 1. The general improvement rates of subjective symptoms in upper G-1 diseases were observed in 100%(32/32) for NRM and in 92%(23/25) for OTA. 2. The overall effective rates in terms of the symptoms and endoscopic findings were 88.9%(32/36) for NRM and 85.2%(23/27) ,or OTA respectively. 3. In NRM group, no significant side effects by NRM were observed except a mild and transient vomiting in one patient, but in OTA group treatment was discontinued due to nousea in one patient, However, there were no clinically significant changes detected in the laboratory parameters. According to the result of this trial, it is cocluded that NRM was safe and effective and (but not statistically significant) was superior to OTA in the treatment of gastrointestinal diseases caused by gastritis, gastric and duodenal ulcer, functional gastrointestinal disorder, non-ulcer dyspepsia etc.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.26 no.2
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• pp.88-97
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• 2013

Objectives : 본 연구를 통해 정신과적, 소화기성으로 유발된 히스테리성 구를 반하백출천마탕과 자음건비탕으로 치료한 1례를 보고하려 한다. Methods : 오심, 불면, 이명, 소화불량, 초조, 두통, 매핵기를 주소로 하는 23세 여성 환자를 대상으로 약 4개월 동안 침구, 반하백출천마탕과 자음건비탕으로 치료하였다. Results & Conclusions : 4개월 동안의 치료 후, 히스테리성 구와 다른 증상들이 소실되었다. 이 논문에서는, 소화기계 장애와 정신 질환 치료를 위해 오랫동안 사용되어온 반하백출천마탕과 자음건비탕을 히스테리성 구 치료에 이용하였다. 결론적으로, 본 연구는 히스테리성 구와 소화기계 장애가 밀접한 관련이 있음과 히스테리성 구에 대한 한의학적 치료의 중요성을 제시하였다.

• Korean journal of aerospace and environmental medicine
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• v.30 no.1
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• pp.34-39
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• 2020

The medical fitness of pilots is part of the civil aviation safety scenery. This study aimed to analyze the health problems occurring among Korean commercial pilots. Three data sources were used to identify the health problems: 7,574 aviation medical examination data, 5,400 sick leaves and 39 cases of a decrease in medical fitness during flight duty period and layover of Korean commercial pilots who have been working for K airline from Jan. 1, 2016 to Dec. 31, 2018. This study was retrospectively analyzed using SPSS 22 statistical program. Waiver of medical certificates was an average 11.9% of total issuance for 3 years, with a denial of 0.1%. The leading cause of denial of medical certificates was predominantly of cardiovascular cause (55.6%). Mild respiratory and digestive disease accounted for 82% of total sick prevalence and 68% of total sick days. The psychiatric and cardiovascular disease were ranked high according to the number of days lost per case. The most common cause of decrease in medical fitness during flight duty period was acute abdominal pain (36.4%) and musculoskeletal disorder (40%) when staying abroad. Aeromedical emphasis on minimizing cardiovascular risk remains appropriate. Major pilot health problems identified in this study should be considered in establishing pilot health promotion programs for aviation safety.