• Archives of Plastic Surgery
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• 제41권6호
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• pp.759-767
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• 2014

Background Infection caused by nontuberculous mycobacteria (NTM) has been increasing. Awareness of this infection is crucial yet problematic. Delayed management may lead to destructive results. We empirically treated a series of patients with clinical suspicion of NTM infection prior to the identification of the pathogen. Methods A total of 12 patients who developed surgical site infections between January 2011 and February 2014 were reviewed. Patients with a skin and subcutaneous infection resistant to standard management over two weeks, and previous history of aesthetic procedures within three months were regarded as highly suspected of having an NTM infection. A variety of diagnostic modalities were examined simultaneously, along with starting empirical treatment including a combination of clarithromycin and moxifloxacin, and surgical debridement. Results All wounds healed completely within 4 weeks. The mean follow-up duration was 7.2 months, and none of the patients developed relapse. Specific NTM pathogens were identified in six patients. Eight patients showed caseating granuloma implying an NTM infection. One patient showed an uncommon Stenotrophomonas infection, which was successfully treated. Three patients had no evidence of a pathogen despite repeated microbial tests. Complications such as scarring, pigmentation, and disfigurement were common in all the patients. Conclusions NTM should be considered in the differential diagnosis of an unusual skin and soft-tissue infection. We propose an empirical regimen of clarithromycin and moxifloxacin as an efficient treatment option for an NTM infection.

• 한국잡초학회지
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• 제4권1호
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• pp.96-106
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• 1984

Changes in weed floras and development of plant resistance to herbicides seemed to be closely related with increased and repeated use of herbicides. Herbicide use increased from 5% of the total consumption of pesticide in 1950 to 45% in 1976 in world basis. About 200 herbicides have been introduced to agriculture so as to control about 206 weed species which have been recorded important to human beings. In Korea, there was about 351 times in increased use of herbicides from 1966 to 1982. Interspecific selection by herbicide is mainly responsible for changes in weed floras and resulted in varying tolerance or susceptibility to herbicides, together with the changes of agricultural practices. The present trend toward continuous cereal cultivation throughout world will lead to type of changes in weed floras favorable to therophyte which can survive under unfavorable conditions as seeds rather than the types of geophyte which can survive unfavorable seasons as buds placed below soil surface. However, geophyte such as Sagitaria pygmaea, and Scirpus jurtcoides, and Cyperus rotundus and Cynodon dactylon in temperate warm climate become severe paddy weeds, presumably because of the removal of annual weeds by herbicides. Since differential tolerance to 2,4-D was firstly reported in Agrostis stolofera, about 30 species of weeds in 18 genera are presently known to have developed resistance to triazine herbicides. Resistance of weed biotypes to triazine herbicide is not mainly due to limited absorption and translocation or to the difference in metabolism, but is the result of biochemical changes at the site of metabolic activity, such as a loss of herbicide affinity for triazine binding site in the photosystem II complex of the chloroplast membrane. Genetical study showed that plastid resistance to triazine was wholly inherited through cytoplasmic DNA in the case of Brassica campestris. Plant tissue culture method can be utilized as an alternate mean of herbicide screening and development of resistance variants to herbicides as suggested by Chaleff and Parsons. In this purpose, one should be certain that the primary target process is operational in cell culture. Further, there are a variety of obstacles in doing this type of research, particularly development of resistance source and it's regeneration because cultured cells and whole plants represent different developmental state.

• 한국산학기술학회논문지
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• 제14권5호
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• pp.2550-2558
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• 2013

주사슬에 oligo(oxy ethylene) 팬던트를 갖는 poly(o-hydroxyamides)(PHAs) 공중합체를 저온에서 용액 중축합 반응에 의해서 합성하였다. 이들 공중합 전구체들의 특성은 1H-NMR, FT-IR, DSC, TGA, UTM 그리고 LOI 등을 이용하여 조사하였다. $35^{\circ}C$의 DMAc 또는 DMAc/LiCl 용액하에서 측정된 PHAs의 고유점성도는 0.74~1.42 dL/g의 범위를 보였다. 전구체들의 용해도는 oligo(oxy ethylene) 단위의 증가와 함께 증가하였으나, polybenzexazoles(PBOs)는 다양한 용매에도 거의 용해되지 않았다. 공중합 전구체들의 분해온도는 질소분위기하에서 $408{\sim}664^{\circ}C$의 범위를 보였고, $900^{\circ}C$에서 char 수득률은 13~59%의 값을 보였다. 공중합 전구체들의 기계적 성질과 난연특성은 oligo(oxy ethylene) 단위가 증가함에 따라 감소하였다.

• 한국조경학회지
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• 제34권6호
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• pp.54-65
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• 2007

There is little research on the exterior spaces or gardens of single detached urban dwellings in Korea because apartments are the general housing type of most inhabitants. However there is an increasing demand for idyllic houses in the urban fringe and for environmentally friendly dwellings or healthy houses that is represented in urban residents gardening activities. The purpose of this research is to analyze residents' preferences and problems in gardening and management of single detached urban dwellings, and to evaluate the possibility of gardens as biotopes. It also addresses the issue of providing public amenities in the urban landscape. One hundred thirty-six dwellings were selected in residential areas of the city of Gwangju. The layout and plant composition, residents' evaluation and understanding of their own gardens, and maintenance and management were investigated. The results indicated that residents associate gardening with mental health and recognized a lack of space as one environmental restriction. Watering was seen as a primary difficulty for maintaining gardens. This research suggests that providing space for gardening could be a tool for participatory community making. When considering the important aspects of gardening, residents responded that gardens offer naturalness, scenic beauty, and practicality and also felt that gardens provide a buffer from environmental pollution and relief from mental duress. Results from the factor analysis using 15 semantic differential variables showed that 'spatial openness', 'natural variety' and 'familiarity' were representative factors. Although a garden is mainly considered as a space for the appreciation of nature with plant material, our results suggest that meaning and environmental symbolism are important elements.

• 한국콘텐츠학회논문지
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• 제13권6호
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• pp.246-259
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• 2013

본 연구는 60세 이상 노인들을 대상으로 노인들의 생활만족도에 미치는 결정요인들의 차별적 영향을 탐구하는데 그 목적이 있으며, 이를 위해서 노인 생활만족도 결정요인으로 다양한 건강, 경제, 여가활동, 사회적 지지 및 심리 요인 관련 변수들을 포괄적으로 검토하였다. 본 연구를 위해 서울 소재 10개 노인종합복지관, 노인대학 및 노인문화센터의 여가활동 프로그램에 참여하고 있는 60세 이상 노인 347명을 대상으로 자료를 수집하였다. 자료수집방법으로는 구조화된 설문지를 사용하였으며, 가설검증을 위한 주된 자료분석방법으로는 구조방정식모형분석기법을 사용하였다. 연구결과 건강요인인 주관적 건강상태, 경제적 요인인 주관적 경제수준, 여가활동요인인 생산적 여가활동과 소비적 여가활동, 사회적지지 요인인 배우자 지지와 자녀지지 그리고 심리적 요인인 자아존중감과 외향성이 노인의 생활만족도에 유의미한 영향을 미치는 것으로 나타났다. 본 연구결과가 갖는 이론적 실천적 함의를 논의하고 향후 연구방향을 제시하였다.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 1993년도 Proceedings of International Conference for Agricultural Machinery and Process Engineering
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• pp.443-452
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• 1993

Direct freezing tests of soybean seed by liquid nitrogen were carried out at various moisture contents and the following important conclusions were drawn from the results of temperature measurements of soybean seed and photographs of bubbles generated on its surface : 1) Assuming that the temperature gradient in a soybean seed is negligible because of its small seed size and the freezing ratio is followed the Heiss's formula, and a differential equation based on the heat energy balance was introduced . The equation was easily solved by the Runge-Kutta-Gill method and the predicted values of the temperature were in good agreement with the observed data. 2) The photographs of bubble generation during freezing showed the boiling mode was nucleate, and then the most suitable formula on the nucleate boiling heat transfer was introduced from many formulate proposed up to now by fitting the calculated values based on the formula to the observed data. The formula used for the predict on of the seed temperature was as follows: $\frac{{\partial}T_s}{\partial\theta}\;=\;-\frac{{\alpha}(T_s\;-\;T_L)^{3.3}}{W(C_s\;-\;\frac{{\delta}m(CT_s\;+\;{\sigma})}{T_s^2})}$ where C = difference of the specific heat between pure ice and water m=moisture content of soybean seed $T_s$ = seed temperature $T_L$ = Temperature of liquid nitrogen W = mass of soybean seed $\alpha$ = proportional constant $\delta$ = constant depends on variety or the type of seed $\theta$ = time $\sigma$ = latent heat of melting of pure ice This study will give important information in the hydro-freezing technique by liquid nitrogen, available as a new technique of processing agricultural products in the near future.

• Structural Engineering and Mechanics
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• 제49권4호
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• pp.427-448
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• 2014

At present, the time of easy oil and gas is over. Now, the largest part of fossil fuels is concentrated in the deepest levels of tectonic structures and in the sea shelves. One of the most cumbersome operations of their extraction is the bore-hole drilling. In connection with austere tectonic and climate conditions, their drivage every so often is associated with great and diversified technological difficulties causing emergencies on frequent occasions. As a rule, they are linked with drill string accidents. A key role in prediction of these situations should play methods of theoretical modelling. For this reason, there is a growing need for development and implementation of new numerical methods for computer simulation of critical and post-critical behavior of drill strings (DSs). In this paper, the processes of non-linear deforming of a DS in cylindrical cavity of a deep bore-hole are considered. On the basis of the theory of curvilinear flexible rods, non-linear constitutive differential equations are deduced. The effects of the longitudinal non-uniform preloading, action of torque and interaction between the DS and the bore-hole surface are taken into account. Owing to the use of curvilinear coordinates in the constraining cylindrical surface and a specially chosen concomitant reference frame, it became possible to separate the desired variables and to reduce the total order of the equation system. To solve it, the method of continuation the solution by parameter and the transfer matrix technique are applied. As a result of the completed numerical analysis, the critical states of the DS loading in the cylindrical channels of inclined bore-holes are found. It is shown that the modes of the post-critical deforming of the DS are associated with its irregular spiral curving prevailing in the zone of bottom-hole-assembly. The possibility of invariant state generation during post-critical deforming is established, condition of its bifurcation is formulated. It is shown that infinite variety of loads can correspond to one geometrical configuration of the DS. They differ each from other by contact force functions.

• 한국콘텐츠학회논문지
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• 제20권7호
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• pp.212-222
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• 2020

본 연구의 목적은 전 세계 산업수학의 흐름을 주도하는 미국산업응용수학 학회에서 출판하는 논문들의 연구현황 및 동향을 거시적으로 파악하는 데 있다. 이를 위해 2016년부터 2019년까지 6,255편의 논문 제목 및 초록을 수집하였으며, LDA 기법을 활용한 토픽모델링과 시계열회귀모형 분석을 수행하였다. 분석 결과 첫째, 산업수학 분야는 해석학을 중심으로 기하학, 대수학, 위상수학, 이산수학, 확률 및 통계 등 다양한 분야에서 연구가 진행되었다. 둘째, 시간이 흐름에 따라 상승하는 연구 주제는 수리유체역학, 그래프이론, 확률미분방정식이었으며, 하강하는 연구 주제는 계산이론과 고전기하로 나타났다. 연구 결과는 산업수학 분야의 지적 구조에 대한 전체적인 흐름 및 변화에 대한 이해를 바탕으로 연구자들에게는 향후 연구 방향에 대해서, 그리고 교육 현장에는 시대 변화를 반영한 산업수학 교육과정을 수립하는데 시사점을 제공할 것이다.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
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• pp.741-762
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• 2003

Ginsenosides, the major active ingredients of ginseng, show a variety of biomedical efficacies such as anti-aging, anti oxidation and anti-inflammatory activities. To understand the effects of compound K (20-O-D-glucopyranosyl-20 (S)-protopanaxadiol), one of the major metabolite of ginsenosides on the skin, we assessed the expression level of ∼ 100 transcripts in compound K-treated HaCaT cells using cDNA microarray analysis. Compound K treatment induced differential expression of 21 genes, which have been reported to be involved in the organization of ECM structure as well as defense responses in human skin cells. One of the most interesting findings is 2-fold increase in hyaluronan synthase2 (HAS2) gene expression by compound K. We found that change in expression of HAS2 gene represents a specific response of HaCaT cells to compound K because hyaluronan synthase 1, 3 was not changed by treatment with compound K. We also demonstrated that the compound K effectively induced hyaluronan synthesis in human skin cells and hairless mouse skin. The human clinical study indicates that topical application of compound K-containing oil-in-water emulsion showed improvement of xerosis, wrinkle and fine lines in the aged skin. We concluded that compound K has anti-aging effects by the induction of HAS2 gene expression and following hyaluronan synthase.

• 한국자기학회지
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• 제3권3호
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• pp.229-233
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• 1993

광자기 디스크의 제조시 기록막내부의 산소함량에 따른 기록 및 자기적 특성의 변화를 연구하였다. 기록막내의 산소함량 변화는 반응성 스퍼터링에 의해 조절하였으며 스퍼터링 전과정 동안 산소의 거동을 in-situ 잔류가스분석기로 조사하였다. 산소함량의 증가에 따라 보자력은 감 소하였으나 수직이방성 및 수직 각형비등은 변화하지 않았다. 대부분의 첨가된 산소는 스퍼터링 과정중 소모되어 Tb원자와 안정한 산화물을 형성하여 자기적 조성의 변화를 초래하였지만 임계기 록크기와 임계외부자계크기에만 약간의 변화를 가져왔을 뿐 디스크의 기록신호잡음비에는 별로 영향을 미치지 않았다. 또한 디스크의 신뢰도면에서도 크게 감소하지 않았다.