• Title/Summary/Keyword: Differential variety

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Malignant Solitary Fibrous Tumor of Tandem Lesions in the Skull and Spine

  • Son, Seong;Lee, Sang-Gu;Jeong, Dong-Hae;Yoo, Chan Jong
    • Journal of Korean Neurosurgical Society
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    • v.54 no.3
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    • pp.246-249
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    • 2013
  • A solitary fibrous tumor (SFT) is a rare neoplasm originated from the pleura, but they can occur in a variety of extrathoracic regions. Although many cases of primary SFT have been reported, there are extremely rare repots to date of a malignant SFT in the spine or skull. A 54-year-woman visited our hospital due to low back pain and both leg radiating pain. Several imaging studies including magnetic resonance imaging and computed tomography revealed expansive enhanced lesions in the occipital bone, T8, S1-2, and ilium, with neural tissue compression. We performed surgical resection of the tumor in each site, and postoperative radiosurgery and chemotherapy were performed. However, after six months, tumors were recurred and metastasized in multiple regions including whole spine and lung. The authors report here the first case of patient with malignant SFT of tandem lesions in the various bony structures, including skull, thoracic spine, and sacral spine, with a rapid recurrence and metastasis. Although malignant SFT is extremely rare, it should be considered in the differential diagnosis and carful follow-up is needed.

Proteomic Analysis in ob/ob Mice Before and After Hypoglycemic Polysaccharide Treatments

  • Kim, Sang-Woo;Hwang, Hye-Jin;Baek, Yu-Mi;Hwang, Hee-Sun;Yun, Jong-Won
    • Journal of Microbiology and Biotechnology
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    • v.19 no.10
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    • pp.1109-1121
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    • 2009
  • In an attempt to discover novel biomarker proteins in type 2 diabetes prognosis, we investigated the influence of hypoglycemic extracellular polysaccharides (EPS) obtained from the macrofungus Tremella fuciformis on the differential levels of plasma proteins in ob/ob mice using two-dimensional gel electrophoresis (2-DE). The 2-DE analysis demonstrated that 92 spots from about 900 visualized spots were differentially regulated, of which 40 spots were identified as principal diabetes-associated proteins. By comparing control with EPS-fed mice, we found that at least six proteins were significantly altered in ob/ob mice, including Apo A-I, IV, C-III, E, retinol-binding protein 4, and transferrin, and their levels were interestingly normalized after EPS treatment. Western blot analysis revealed that the altered levels of the two regulatory molecules highlighted in diabetes and obesity (e.g., resistin and adiponectin) were also normalized in response to EPS. The Mouse Diabetes PCR Array profiles showed that the expression of 84 genes related to the onset, development, and progression of diabetes were significantly downregulated in liver, adipocyte, and muscle of ob/ob mice. EPS might act as a potent regulator of gene expression for a wide variety of genes in ob/ob mice, particularly in obesity, insulin resistance, and complications from diabetes mellitus.

Differential induction of allergy responses by low molecular weight wheat proteins from six wheat cultivars

  • Cho, Miju;Lee, Hyeri;Hwang, Min Hee;Cheong, Young-Keun;Kang, Chon-Sik;Lee, Nam Taek;Chung, Namhyun
    • Journal of Applied Biological Chemistry
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    • v.60 no.1
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    • pp.55-59
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    • 2017
  • Although wheat is a common staple food in the world, some people suffer from a variety of wheat allergies. For example, wheat-dependent exercise-induced anaphylaxis is induced in the gastrointestinal tract by wheat proteins. Relatively high molecular weight proteins that are salt-insoluble induce many wheat allergies. In the present study, we investigated the induction of an allergy response using crude wheat proteins, which are relatively low molecular weight, salt-soluble proteins. The crude antigen used in this study was extracted using phosphate buffered saline. When the antigen extracts from various wheat cultivars were orally administered, differentiable degrees of allergy responses were observed as measured by serum IgE and histamine secretion compared to the control. Serum IgE levels increased following administration of three of the wheat extracts. This evidence suggests that a combination of salt-soluble wheat proteins could be antigens for the induction of various allergy responses.

A Study on Preference of University Students for Interior Design Characteristics of Living Room - Focused on Color, Image and Style in Interior Design of Living Room - (대학생이 선호하는 거실의 실내 디자인 특성에 관한 연구 - 거실의 실내 색채, 이미지, 스타일을 중심으로 -)

  • Jung, Yoon-Hye;Shin, Hwa-Kyoung
    • Korean Institute of Interior Design Journal
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    • v.17 no.6
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    • pp.207-215
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    • 2008
  • Modern people come to have high standard and variety need for the oneself expression these days. This phenomenon also, appears in the house space clearly. There are design characteristics in an element expressing a lifestyle and personality in the house space and a living room is the space that is important at time to do a design characteristics plan. Therefore, this study is going to analyze the design characteristics of the apartment house which is a representative house type these days. Concretely, there are design characteristics that a color, an Image, a style. This study used questionary survey from June 10, 2008 to July 9. The color analyzed a color and tone through a color palette of PCIS and the living room image used SD(semantic differential method) method by a concrete analysis method. The result of the analysis were as follows; 1) Various colors and tone were prefer in a house future than the house where lived in. 2) It was done prefer to 'comfort' image for the future living room image in the future but 'provocative' image and 'splendid' were not done a choice 3) A 'modern style' was done prefer to of with a house living room style in the future.

Improving CMD Areal Density Analysis: Algorithms and Strategies

  • Wilson, R.E.
    • Journal of Astronomy and Space Sciences
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    • v.31 no.2
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    • pp.121-130
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    • 2014
  • Essential ideas, successes, and difficulties of Areal Density Analysis (ADA) for color-magnitude diagrams (CMD's) of resolved stellar populations are examined, with explanation of various algorithms and strategies for optimal performance. A CMD-generation program computes theoretical datasets with simulated observational error and a solution program inverts the problem by the method of Differential Corrections (DC) so as to compute parameter values from observed magnitudes and colors, with standard error estimates and correlation coefficients. ADA promises not only impersonal results, but also significant saving of labor, especially where a given dataset is analyzed with several evolution models. Observational errors and multiple star systems, along with various single star characteristics and phenomena, are modeled directly via the Functional Statistics Algorithm (FSA). Unlike Monte Carlo, FSA is not dependent on a random number generator. Discussions include difficulties and overall requirements, such as need for fast evolutionary computation and realization of goals within machine memory limits. Degradation of results due to influence of pixelization on derivatives, Initial Mass Function (IMF) quantization, IMF steepness, low Areal Densities ($\mathcal{A}$), and large variation in $\mathcal{A}$ are reduced or eliminated through a variety of schemes that are explained sufficiently for general application. The Levenberg-Marquardt and MMS algorithms for improvement of solution convergence are contained within the DC program. An example of convergence, which typically is very good, is shown in tabular form. A number of theoretical and practical solution issues are discussed, as are prospects for further development.

Pituitary Apoplexy Presenting as Isolated Third Cranial Nerve Palsy with Ptosis : Two Case Reports

  • Cho, Won-Jin;Joo, Sung-Pil;Kim, Tae-Sun;Seo, Bo-Ra
    • Journal of Korean Neurosurgical Society
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    • v.45 no.2
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    • pp.118-121
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    • 2009
  • Pituitary apoplexy is a clinical syndrome caused by an acute ischemic or hemorrhagic vascular accident involving a pituitary adenoma or an adjacent pituitary gland. Pituitary apoplexy may be associated with a variety of neurological and endocrinological signs and symptoms. However, isolated third cranial nerve palsy with ptosis as the presenting sign of pituitary apoplexy is very rare. We describe two cases of pituitary apoplexy presenting as sudden-onset unilateral ptosis and diplopia. In one case, brain magnetic resonance imaging (MRI) revealed a mass in the pituitary fossa with signs of hemorrhage, upward displacement of the optic chiasm, erosion of the sellar floor and invasion of the right cavernous sinus. In the other case, MRI showed a large area of insufficient enhancement in the anterior pituitary consistent with pituitary infarction or Sheehan's syndrome. We performed neurosurgical decompression via a transsphenoidal approach. Both patients showed an uneventful recovery. Both cases of isolated third cranial nerve palsy with ptosis completely resolved during the early postoperative period. We suggest that pituitary apoplexy should be included in the differential diagnosis of patients presenting with isolated third cranial nerve palsy with ptosis and that prompt neurosurgical decompression should be considered for the preservation of third cranial nerve function.

Suspected Case of Exocrine Pancreatic Insufficiency in a Bengal Tiger (Panthera tigris tigris)

  • Rhim, Haerin;Han, Jae-Ik
    • Journal of Veterinary Clinics
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    • v.35 no.5
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    • pp.240-242
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    • 2018
  • A 1-year-old, female Bengal tiger (Panthera tigris tigris) presented signs of weight loss and dark browncolored diarrhea. On fecal examination, numerous intact and broken red blood cells were found, but both parasites and inflammatory signs were absent. No significant findings were seen in serum biochemistry profiles, including electrolytes, with negative feline pancreatic lipase immunoreactivity (fPLI). Diagnostic kits using feces or peripheral blood were negative for feline parvovirus, feline coronavirus, feline immunodeficiency virus, and feline leukemia virus. Based on the result of feline trypsin-like immunoreactivity (fTLI) concentration ($4.6{\mu}g/L$), the tiger was provisionally diagnosed to have exocrine pancreatic insufficiency (EPI). After this diagnosis, pancreatic enzymes were prescribed. The feces of the tiger returned to normal form and her weight was increasing. EPI is uncommon and not described extensively in Felidae, including domestic cats. Feline EPI is associated with a variety of non-specific signs and it should be considered in the differential diagnosis of cases presenting with weight loss, diarrhea, and other gastrointestinal signs. In this case, the patient was strongly suspected to have EPI based on the very low fTLI concentration, though the concentration of fTLI in tigers has not yet been determined. This is the first report to present a suspected EPI case in Bengal tigers.

Structural and thermal characteristics of photocrosslinked silk fibroin - PEG hydrogel

  • Jo, You-Young;Lee, Kwang-Gill;Bragg, John C.;Lin, Chien-Chi;Kweon, HaeYong
    • International Journal of Industrial Entomology and Biomaterials
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    • v.32 no.1
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    • pp.35-40
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    • 2016
  • Hydrogels are crosslinked hydrophilic matrices for a variety of biomedical applications. Silk fibroin (SF), one of typical natural biomaterials, has been explored as base material for hydrogel. Photocrosslinked SF hydrogel containing poly(ethylene glycol) (PEG) was formulated through visible light initiated thiol-acrylate photopolymerization. The morphological, structural and thermal properties of SF - PEG hydrogel was investigated through scanning electron microscopy, X-ray diffractometry, thermogravimetry, and differential scanning calorimetry. The morphology of SF hydrogel showed dot and uneven surface with network cross-section. X-ray diffraction curves showed that the specific diffraction peaks of PEG were not changed by the intensity of the peaks were affected by sonication. Thermo-degradation behavior of SF - PEG hydrogel sonicated was significantly affected and became complex pattern compared to unsonicated ones. However, the melting endothermic temperature of SF - PEG hydrogel was not changed but the crystalline enthalpy was decreased by gelation and sonication.

The Effects of Paternal and Maternal Control on Self-Esteem in School-Age Boys and Girls : The Mediating Role of Autonomy (부와 모의 통제가 남녀 아동의 자아존중감에 미치는 영향 : 자율성의 매개적 역할)

  • Lee, Mi-Jung;Doh, Hyun-Sim;Chee, Yeon-Kyung
    • Korean Journal of Child Studies
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    • v.32 no.5
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    • pp.67-84
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    • 2011
  • This study examined the effects of parental control and children's autonomy on self-esteem, using a sample of 415 school-age children (208 boys and 207 girls) recruited in Seoul. Ordinary Least Square regressions revealed a variety of gender-based differences in the associations among these three variables. Boys with high maternal behavioral control had high levels of self-esteem, whereas girls under low paternal psychological and high behavioral control reported high levels of self-esteem. Boys with high maternal behavioral control and girls with high paternal behavioral control also reported high levels of autonomy. Autonomy was found to exert a positive impact on self-esteem for both boy and girls. Autonomy played a mediating role in the relationships between maternal behavioral control and self-esteem for boys, and between paternal behavioral control and self-esteem for girls. These findings highlight the differential influences of psychological control and behavioral control on autonomy and self-esteem, as well as the relative impact of the opposite sex parent on the development of autonomy and self-esteem in late childhood.

Experimental Study on Tip Clearance Effects for Performance Characteristics of Ducted Fan

  • Raza, Iliyas;Choi, Hyun-Min;Cho, Jin-Soo
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2009.11a
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    • pp.395-398
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    • 2009
  • Currently, a new generation of ducted fan UAVs (Unmanned Aerial Vehicles) is under development for a wide range of inspection, investigation and combat missions as well as for a variety of civil roles like traffic monitoring, meteorological studies, hazard mitigation etc. The current study presents extensive results obtained experimentally in order to investigate the tip clearance effects on performance characteristics of a ducted fan for small UAV systems. Three ducted fans having different tip clearance gap and with same rotor size were examined under three different yawed conditions of calibrated slanted hot-wire probe. Three dimensional velocity flow fields were measured from hub to tip at outlet of the ducted fan. The analysis of data were done by PLEAT (Phase locked Ensemble Averaging Technique) and three non-linear differential equations were solved simultaneously by using Newton -Rhapson numerical method. Flow field characteristics such as tip vortex and secondary flow were confirmed through axial, radial and tangential velocity contour plots. At the same time, the effects of tip clearance on axial thrust and input power were also investigated by using wind tunnel measurement system. For enhancing the performance of ducted fan, tip clearance level should be as small as possible.

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