• International Journal of Industrial Entomology and Biomaterials
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• v.23 no.2
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• pp.231-238
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• 2011

Attacin is an insect antibacterial protein that plays an important role in immune response to injury and infection. In this report, we have isolated and characterized of cDNA encoding for the attacin from the immunized larvae of swallowtail butterfly, $Papilio$ $xuthus$. A full length cDNA of $P.$ $xuthus$ attacin was obtained by employing annealing control primer (ACP)-based differential display PCR and 5' RACE. The complete $P.$ $xuthus$ attacin cDNA was comprised of 949 bp encoding a 250 amino acid precursor. It contains a putative 18 amino acid signal peptide sequence, a 42 amino acid propeptide sequence, and a 190 amino acid mature protein with a theoretical molecular mass of 19904.01 and a pI of 9.13. The putative mature protein of $P.$ $xuthus$ attacin showed 48-52% and 24-30% identity in amino acid sequences with that of lepidopteran and dipteran insects, respectively. Semiquantitive RT-PCR results revealed that the transcript of $P.$ $xuthus$ attacin gene was up-regulated at significant levels after injection with bacterial lipopolysaccharide (LPS). We sub-cloned cDNA fragment encoding mature $P.$ $xuthus$ attacin into the expression vector, highly expressed in $E.$ $coli$ BL21 cells, and its antibacterial activity was analyzed. Recombinant $P.$ $xuthus$ attacin evidenced considerably antibacterial activity against Gram-negative bacteria, $E.$ $coli$ ML 35 and $Klebsiella$ $pneumonia$.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.41 no.3
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• pp.45-54
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• 2004

Microwave characteristics of ridge type CPW traveling-wave(TW) electroabsorption modulator and photodetector are affected by the thickness of intrinsic layer, width of guiding layer, and the separation of signal and ground electrodes. These factors are determined effective index of microwave and characteristic impedance due to changing of capacitance(C) and inductance(L) of device. However, conventional equivalent circuit of TW-structure is approximated to microstrip and CPW transmission line by distribution of electric and magnetic fields, respectively. In this paper, we analyzed microwave characteristics of TW-structure and found more accurate value of C and L by using finite difference time domain (FDTD) method. These values are adopted circuit element of equivalent circuit. Microwave characteristics obtained by the FDTD and equivalent circuit model show good agreement.

• Mycobiology
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• v.43 no.4
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• pp.450-457
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• 2015

Medicinal mushrooms have been used worldwide to treat cancer and modulate the immune system. Over the last several years, there has been increasing interest in isolating bioactive compounds from medicinal mushrooms and evaluating their health beneficial effects. Fomes fomentarius is used in traditional oriental medicine and is known to possess antioxidant, antiinflammatory, antidiabetic, and antitumor effects. In the present study, we isolated fomentariol from Fomes fomentarius and investigated its anti-inflammatory effect in murine macrophages (RAW264.7 cells) stimulated with lipopolysaccharides. Fomentariol inhibited the production of nitric oxide and intracellular reactive oxygen species triggered by lipopolysaccharides. Interestingly, fomentariol differentially regulated cytokine production triggered by lipopolysaccharides. Fomentariol effectively suppressed the production of interleukin-$1{\beta}$ and interleukin-6 but not tumor necrosis factor-${\alpha}$. The inhibitory effect of fomentariol against nitric oxide, interleukin-$1{\beta}$, and interleukin-6 production was possibly mediated by downregulation of the extracellular signal-regulated kinase signaling pathway. Taken together, our results suggest that fomentariol differentially modulated inflammatory responses triggered by lipopolysaccharides in macrophages and is one of the bioactive compounds that mediate the physiological effects of Fomes fomentarius.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.11 no.4
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• pp.287-295
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• 1986

In this paper, a SBC(sub-band-coding) is proposed to code a speech signal for a digital mobile radio and a robustness of speech quality of the SBC over the Rayleigh fading channel is investigated via a computer simulation. First the Rayleigh fading channel and 16-ary DPSK receiver models are presentes and verified its validitties by comparing with theoretical values. Three different measures: SNR, LPC distance measure and subjective listening test, were used to evaluate the effects due to the Rayleigh fading channel errors. From the results of computer simulation at BER=$10_{-3}$, $10_{-2}$, 5$ imes$$10_{-2}$, it was found that the speech remained quite intelligible at BER=$10_{-2}$and the link is still usuable even at BER=5$ imes$$10_{-2}$ Thus it was concluded that the SBC can be applicable to the digital mobile radio on the Rayleigh fading channel error in the range of $10_{-4}$~$10_{-2}$ without emplowing any error correction codes.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.17 no.9
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• pp.939-950
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• 1992

The performance of common spreading code scheme employing multiple-capture receiver is compared to that of transmitter-oriented (T/O) code division multiple access (CDMA) scheme in view of the possibility of collision-free transmissions and the effect of secondary multiple-access interference. For performance comparisons, secondary multiple-access interference is characterized for the common code scheme and the T/O CDMA scheme that assures perfectly collision-free transmissions. Throughput performance is then evaluated for these two schemes with direct-sequence spread-spectrum/differential-phase-shift-keying (DS-SS/DPSK) data modulation and forward-error-control coding (BCH codes) in the presence of an additive white Gaussian noise (AWGN). It is shown that when the number of radios is relatively large, the maximum normalized throughput is greater for the common code scheme than for the T/O CDMA scheme at a moderate signal-to-noise ration(SNR).

• The Journal of Korean Institute of Communications and Information Sciences
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• v.17 no.10
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• pp.1147-1156
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• 1992

In this paper, in order to apply the $\pi/4$ shift QPSK to TCM, we propose the $\pi/8$ shift 8PSK modulation technique and the trellis-coded $\pi/8$ shift 8PSK performing signal set expansion and partition by phase difference. In addition, the Viterbi decoder with branch metrics of the squared Euclidean distance of the first phase difference as well as the Lth phase different is introduced in order to improve the bit error rate(BER) performance in differential detection of the trellis-coded $\pi/8$ shift 8PSK. The proposed Viterbi decoder is conceptually the same as the sliding multiple detection by using the branch metric with first and Lth order phase difference. We investigate the performance of the uncoded $\pi/4$ shift QPSK and the trellis-coded $\pi/8$ shift 8PSK with or without the Lth phase difference metric in an additive white Gaussian noise (AWGN) using the Monte Carlo simulation. The study shows that the $\pi/4$ shift QPSK with the Trellis-code i.e. the trellis-coded $\pi/8$ shift 8PSK is an attractive scheme for power and bandlimited systems and especially, the Viterbi decoder with first and Lth phase difference metrics improves BER performance. Also, the nest proposed algorithm can be used in the TC $\pi/8$ shift 8PSK as well as TCMDPSK.

• Environmental Mutagens and Carcinogens
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• v.25 no.1
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• pp.40-46
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• 2005

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) displays high toxicity in animals and has been implicated in human carcinogenesis. Although the mechanism of carcinogenesis by TCDD is unclear, it is considered to be a non-genotoxic compound and tumor promoter. In our experiment, we investigated the effects of TCDD on gene expression in mouse skin carcinogenesis. We used cDNA microarray to detect the differential gene expression in tumors induced in hairless mouse skin by MNNG plus TCDD protocol. We found that erb-2, c-ets2 and p27$^{kip1}$ were significantly up-regulated, but TNFR2, AKT-l, integrin $\beta$l, maspin, IGF-l, c-raf-l, Rb were significantly down-regulated, in tumor region, respectively. We also found that the expression of 53 genes involved in cen cycle, signal transduction, apoptosis, adhesion molecule, angiogenesis, and invasion, were changed two fold more, in tumor surrounding region. These data suggest that TCDD alters the expression of a large array of genes involved in apoptosis, cytokine production and angiogenesis in mouse skin carcinogenesis.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.5
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• pp.1047-1054
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• 2012

Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice, and its risk increases with age. Conventionally, the way of detecting AF was the time·frequency domain analysis of RR variability. However, the detection of ECG signal is difficult because of the low amplitude of the P wave and the corruption by the noise. Also, the time·frequency domain analysis of RR variability has disadvantage to get the details of irregular RR interval rhythm. In this study, we describe an atrial fibrillation pattern analysis based on symbolization and information entropy. We transformed RR interval data into symbolic sequence through differential partition, analyzed RR interval pattern, quantified the complexity through Shannon entropy and detected atrial fibrillation. The detection algorithm was tested using the threshold between 10ms and 100ms on two databases, namely the MIT-BIH Atrial Fibrillation Database.

• KIPS Transactions on Computer and Communication Systems
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• v.2 no.2
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• pp.83-92
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• 2013

RSA-CRT is a widely used algorithm that provides high performance implementation of the RSA-signature algorithm. Many previous studies on each operation step have been published to verify the physical leakages of RSA-CRT when used in smart devices. This paper proposes SAED (subtraction algorithm analysis on equidistant data), which extracts sensitive information using the event information of the subtraction operation in a reduction algorithm. SAED is an attack method that uses algorithm-dependent power signal changes. An adversary can extract a key using differential power analysis (DPA) of the subtraction operation. This paper indicates the theoretical rationality of SAED, and shows that its results are better than those of other methods. According to our experiments, only 256 power traces are sufficient to acquire one block of data. We verify that this method is more efficient than those proposed in previously published studies.

• Journal of Biosystems Engineering
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• v.41 no.4
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• pp.319-327
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• 2016

Purpose: Automated guidance systems (AGSs) for mobile farm machinery have several advantages over manual operation in the crop production industry. Many researchers and companies have tried to develop such a system. However, it is not easy to evaluate the performance of an AGS because there is no established device used to evaluate it that complies with the ISO 12188 standard. The objective of this study was to develop a tracking sensor system using five laser distance measurement sensors. Methods: One sensor-for long-range distance measurement-was used to measure travel distance and velocity. The other four sensors-for mid-range distance measurement-were used to measure lateral deviation. Stationary, manual driving, and A-B line tests were conducted, and the results were compared with the real-time kinematic differential global positioning system (RTK-DGPS) signal used by the AGS. Results: For the stationary test, the average error of the tracking sensor system was 1.99 mm, and the average error of the RTK-DGPS was 15.19 mm. For the two types of driving tests, the data trends were similar. A comparison of the changes in lateral deviation showed that the data stability of the developed tracking system was better. Conclusions: Although the tracking system was not capable of measuring long travel distances under strong sunlight illumination because of the long-range sensor's limitations, this dilemma could be overcome using a higher-performance sensor.