• Asian-Australasian Journal of Animal Sciences
• /
• 제15권6호
• /
• pp.828-833
• /
• 2002

Thirty mature pregnant ewes of the Phan Rang breed with an initial live weight of 30 to 45 kg were used to compare the effects of three different diets in late pregnancy on ewe and lamb performance. All diets contained 20% of whole sugar cane, 16% rice bran, 26% cassava root and 6% molasses urea block. The remaining 32% of dry matter consisted of Jackfruit (JF diet), 16% each of Jackfruit and Cassava foliage (JF+CS diet) or Jackfruit and Flemingia foliage (JF+FM diet). The diets were fed at 3.5% of actual BW of the individual animal. The foliages were offered at 120% of the amount decided in the diets of the requirements. The JF+CS diet resulted in significantly higher feed intake than the JF diet, and also a higher feed intake than the JF+FM diet, but this difference was not significant. The ewe weight changes during the last 8 weeks of pregnancy, or from start to 24 h after lambing, were significantly different. The highest weight gain was obtained from the ewes fed the JF+CS diet. Diets had no effect on weight changes of ewes during 3 weeks after lambing but a significant effect on the litter birth weight, with the JF+CS diet giving the highest litter birth weight. There was, however, no effect on the litter weight at 21 days or litter growth rate from birth to 21 days due to the experimental diets.

• Nutrition Research and Practice
• /
• 제11권4호
• /
• pp.281-289
• /
• 2017

BACKGROUND/OBJECTIVE: The incidence of colorectal cancer (CRC) has been attributed to higher intake of fat and protein. However, reports on the relationship between protein intake and CRC are inconsistent, possibly due to the complexity of diet composition. In this study, we addressed a question whether alteration of protein intake is independently associated with colonic inflammation and colon carcinogenesis. MATERIALS/METHODS: Balb/c mice were randomly divided into 4 experimental groups: 20% protein (control, 20P, 20% casein/kg diet), 10% protein (10P, 10% casein/kg diet), 30% protein (30P, 30% casein/kg diet), and 50% protein (50P, 50% casein/kg diet) diet groups and were subjected to azoxymethane-dextran sodium sulfate induced colon carcinogenesis. RESULTS: As the protein content of the diet increased, clinical signs of colitis including loss of body weight, rectal bleeding, change in stool consistency, and shortening of the colon were worsened. This was associated with a significant decrease in the survival rate of the mice, an increase in proinflammatory protein expression in the colon, and an increase in mucosal cell proliferation. Further, colon tumor multiplicity was dramatically increased in the 30P (318%) and 50P (438%) groups compared with the control (20P) group. CONCLUSIONS: These results suggest that a high protein diet stimulates colon tumor formation by increasing colonic inflammation and proliferation.

• 대한한방내과학회지
• /
• 제31권4호
• /
• pp.813-828
• /
• 2010

Objective : Yegangji-tang (YJT) is noted in China as effective medicine for hyperlipidemia. This experiment was performed to determine the effects of Yegangji-tang (銳降脂湯: YJT) on antioxidant activity and hyperlipidemia induced by hypercholesterolemic diet in mice. Methods : We observed three experimental groups: normal, control, and treatment. Rats were provided a normal diet in the normal group, and the other groups were provided a hypercholesterolemic diet to induce hyperlipidemia. After 2 weeks, YJT was treated to the treatment group. We observed the change of body and liver weight, change of serum total cholesterol, LDL cholesterol, HDL cholesterol and triglycerides, lipid peroxidation and antioxidant activity of liver tissue, cholesterol gene revelation control efficiency, and histologic change of liver and abdominal aorta. Results : Total cholesterol, LDL cholesterol and triglycerides decreased significantly with YJT, whereas HDL cholesterol increased significantly. Lipid peroxidation decreased and antioxidant activity of the liver increased significantly. Gene revelation of ACAT and HMG-CoA reductase in hepatic tissue decreased significantly with YJT. We also found that tissue defects of the liver and abdominal aorta were controlled by YJT on histologic study. Conclusion : These results suggest that YJT might be effective in treatment and prevention of hyperlipidemia.

• 한방비만학회지
• /
• 제2권1호
• /
• pp.73-82
• /
• 2002

Objectives: The purpose of this study is to investigate the effect of the aerobic exercise and weight training combined with VLCD(very low calorie diet) and chegameuyiin-tang(體減薏苡仁湯) on the change of the body composition during 15 days of hospitalization treatment. Methods: Twenty four female obese patients were observed. Exercise regimen was composed with aerobic exercise and weight training program, and the intensity of aerobic exercise were 50% HRmax(maximal heart rate) twice time a day and weight training were 50% 1RM(one repetition maximum) a day. All subjects diet regimen was VLCD of 600kcal/day. Results & Conclusions. 1. There was no significant difference between the aerobic exercise and the weight training groups in the change of body weight, fat mass, and percent body fat, waist-hip ratio, body mass index and resting metabolic rate. 2. In the comparison of the change rate of FFM(fat free mass), weight training group preserved FFM better than aerobic-exercise-only-group with no statistical significance.

• Journal of Nutrition and Health
• /
• 제28권5호
• /
• pp.442-450
• /
• 1995

This study determined plasma glucose, free fatty acid(ffa), epinephrine, norepinephrine, creatine the phosphokinase(CPK), calcium (Ca), magnesium(Mg) and hydroxyproline, Ca and Mg in the heart muscle. Thirty six male Sprague Dawley rats average weighing 110g divided into two diet group : normal Mg group(0.05% Mg), Marginal Mg group(0.005% Mg). After the rats were on experimental diets for 2 weeks, rats for each group were randomly assigned to stress and no stress group and 30 minutes IMMB stress was administered to stress group every day for two weeks. The following were found : 1) Rats fed normal magnesium diet showed decreased plasma glucose and non signficant change in norepinephrine and CPK with IMMB stress, while magnesium deficient rats showed elevated plasma glucose, norepinephrine and CPK with stress. 2) Myocardial hydroxyproline and plasma epinephrine were not significantly different among groups. 3) In the rats fed adequate magnesium, stress increased plasma magnesium while rats on marginal magnesium diet did not show significant change with stress. 4) Plasma and myocardial calcium were increased in rats fed marginal Mg diet, but did not show any significant difference with stress.

• Journal of Nutrition and Health
• /
• 제14권4호
• /
• pp.151-161
• /
• 1981

The objective of this study was to compare the electrolytes contents in skeletal muscles of two different groups of rats, one for control fed 20% casein diet, and the other experimental group recovered from 7% casein diet as protein restriction feeding for two weeks at the beginning of this experiment. Two different comparison criteria were used in this study, one for comparison between animals at the same age groups and the other between groups weighing same body weight as the control groups. Food consumption of animals for experimental and control groups were ad libitum. Following measurement and samples were collected: body weight, five different muscles-anterior tibialis (A.T.) extensor digitorium longus (E.D.L.) soleus, plantaris, gastrocnemius-for electrolytes and protein analysis. The experimental groups showed lower body weight than that of control group. Same trend was showen in protein content in five different muscles. Magnesium and potassium content in four muscles except gastrocnemius showed lower and sodium higher in experimental groups than those in control group at fourteenth day, after recovery from protein restriction, electrolytes content change showed differently in four muscles. Magnesium and potassium contents were increased as protein content in diet. Sodium content decreased as one week intake of recovery diet started, thereafter it was rather slowly increased. Phosphorus content in gastrocnemius at the second week in experimental group was slightly lower than that of control group, and it recovered rapider while at the same body weight group it was higher in experimental group.

• 대한한의학회지
• /
• 제30권1호
• /
• pp.17-25
• /
• 2009

Objectives: This study was on the pharmaceutical components in purified ginseng total saponin (GTS), coisis semen (CS), the combination of these drugs, and the major component of coicis coixol for the prevention and treatment of obesity. Methods: In this study, to evaluate the effect on the suppression of obesity, high fat diet-induced obese rats were treating with the drugs, the effects on the balance of energy and diet activity were examined, and the change of weight, the change of the intake of diet, body fat rate, etc. were assessed. Results: The results demonstrate that in high fat diet-induced obese white rats, the combination treatment of ginseng total saponin and coicis was effective in suppression of weight gain, reduction of intake of food, and reduction of body fat. Conclusions: The results suggest that a combination treatment with major components of red ginseng total saponin and coicis may be used therapeutically for the suppression and treatment of obesity.

• 한국식품영양학회지
• /
• 제9권2호
• /
• pp.189-200
• /
• 1996

The purpose of this study was to find the effect of honey on the sugar metabolism In Sprague-Dawley rats. All experimental rats were fed ad libitum, for seven weeks, 68% saccharide diet anti 10% or 20% honey from acacia, sumac and miscellaneous flower honey, respectively, and sucrose. The amount of glucose in whole blood was increased in all groups fed with honey except the group fed with 10% sumac honey solution. The amount of fructosamine in serum of rat taken diet with honey solution was increased in comparison with normal group, control group, sucrose group. The amount of fructosamine in serum of rat taken diet with honey solution was high in order of sumac honey > miscellaneous flower honey > acacia honey. The amount of lactate and pyruvate in whole blood of rat taken diet with sucrose group or honey group were decreased in comparison with the normal group and control group. The amount of $\beta$-hydroxybutyrate in serum of rat taken diet with sucrose or honey was increased in comparison with the normal group, control group.

• Journal of Nutrition and Health
• /
• 제21권5호
• /
• pp.324-332
• /
• 1988

Effects of a change in dietary Ca content and an alteration in dietary lipid type on lipid metabolism have been investigated in male Sprague-Dawley rats. The results obtained were summarized as follows ; 1) There was no comparable changes in food consumption and body weight gain among all 9 groups. 2) Serum total lipids and cholesterol were lowest when high Ca-corn all diet was fed, and highest when low Ca-butter diet was fed. 3) The contents of total lipids and cholesterol per g liver and total liver showed no consistent tendency with the dietary treatment. 4) Addition of Ca to the diet caused the significant increase in the dry fecal matter and fecal Ca. And fecal total lipids and fecal cholesterol were much greater if the high-Ca diet was fed than if control and low-Ca diet were fed. It is concluded that Ca and polyunsaturated acids have tendency of hypocholesterolemic effect.

• Journal of Nutrition and Health
• /
• 제30권2호
• /
• pp.155-169
• /
• 1997

This study investigated the effect of weight control by using the commercial appetite suppressant ((-)-hydroxycitric acid(HCA) formula) and nutrition education on 72 obese women over a period of 8 weeks. During the study it conducted nutritional education for women to control their weight, thus analyzed their changes in anthropometric variables. All obese women were randomized in a double-blind method to consume either HCA(HCA group : experimental group) or placebo(placebo group : control group). Two groups were also divided randomly into 2 groups combined with commercial formula diet in 1 meal a day(HD group and PD group : HCA + gormula diet and placebo + formula diet) or not(HO group and conducted with 4 groups(HD, HO, PD, and PO group). All subjects were assigned to consume 800-1500kcal/d balanced diet which is 500kcal less than their usual energy requirement. To evaluate the effect of the weight control program, weight, percent of body fat, waist and hip circumferences, and 5 skinfold thickness were measured up to 5 times in all obese women. The mean weight of the subjects at the onset of the study was 76.5$\pm$10.6kg. The mean body mass index(BMI) wa 30.1$\pm$3.8 and it was in the upper 5 percentile of mean BMI of Korean women. At the end of the program, mean weight loss was 3.5kg after 2 weeks(p<0.001), and 5.8kg after 4 weeks(p<0.001). The waist, hip ratio(WHR) and skinfold thickness measurements of biceps, triceps, subscapular, suprailiac and abdominum showed significant reduction over the entire study period(p<0.05). These outcome were evaluated by effect of nutritional education and counselling. The reduction of % of body fat was significantly different among the 4 groups. Women who administrated HCA demonstrated more change in weight, BMI than the placebo group. There was also significant reduction in body composition (% of body fat, WHR, and skinfold thickness) than the other groups. The HD group which was administrated HCA combined with formula diet was more decreased than other groups. It showed that this program using commercial HCA and formula diet induced not only a change in weight but also a change in body composition. The outcome of this study suggests that HCA has a more effctive change on weight control which is carried out with nutritional education and counselling.