• 한국응용과학기술학회지
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• 제13권2호
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• pp.21-28
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• 1996

Diazotization of STA synthesized by the indirect diazotization method. The effect of catalyst and agitation (rpm) about STA and H-acid reaction were examined and the optimum conditions were investigated experimentally. The yields and characteristics of $1^{.st}$ coupling and diazotization synthesis were identified by HPLC and FT-IR analysis. $1^{.st}$ condensation of CNC and mPDSA were synthesized at $5^{\circ}C$ and pH=6.5. The conditions of alkaly coupling of H-acid were synthesized at $5^{\circ}C$ and pH=8. The condensation of products was identified by U. V. analysis. From this results, It was obtained to reactive dyestuffs of bi-functional reactivity with high fastness and high adsorption.

• 대한화학회지
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• 제56권6호
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• pp.716-719
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• 2012

Diazo coupling reactions of aromatic amines with 2-naphthol in a green, efficient and easy procedure is described. Ferric hydrogensulfate catalyses this reaction in water at room temperature and short reaction time with high yields. The antibacterial activities of the synthesized compounds against four pathogenic bacteria are also investigated.

• 한국응용과학기술학회지
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• 제21권3호
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• pp.246-251
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• 2004

Diazotization of three aminopyridine such as 3-amino-2-chloropyridine, 5-amino-2-chloropyridine, and 3-aminopyridine were investigated. Preparation of pyridinediazonium tetrafluoroborates were carried out employing two different methods. Diazotization of aminopyridines with a chlorine substituent in the pyridine ring were conducted in acidic aqueous solution with sodium nitrite in 70% and 74% yields respectively. 3-Pyridinediazonium tetrafluoroborate without any ring subsituent was unstable in an aquous solution and the diazotiation of 3-aminopyridine was proceded in an anhydrous methylene chloride-etherial $BF_3$ solution with tert-butyl nitrite in 40% yield.

• 한국응용과학기술학회지
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• 제12권2호
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• pp.115-120
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• 1995

Diazotization of 2-Amino-5-nitrophenol was Synthesized by the direct diazotization method. The diazonium salts are usually stabilized in the from of double salts. The double salts of zinc chloride are the Commonest, and the double salt method is Specially applicable to the yield-up of coupling. The azo dye(2-naphthol-1-(2'-diazo-5'-nitrophenol)) is Converted into a chromium Complex by heating($100^{\circ}C$) with chromic formate, and DMF. The removal of inorganic salts from dyestuffs was performed in DMF solvent. This effect was more pronounced. From these results, It was obtained to liquid dyestuffs of metal complex with High fastness and high adsorption.

• Bulletin of the Korean Chemical Society
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• 제23권4호
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• pp.567-570
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• 2002

Diazotization of 3-amino-2-ethoxycarbonylthieno[2,3-b]quinoxaline 1 gave the diazonium salt 2 which was reacted with SO2 and N-methylaniline to give sulfamoylquinoxaline derivatives 3-5. Imidazothienoquinoxaline 8 was obtained from the reaction of carboxylic acid hydrazide 6 with nitrous acid and followed by boilling the carboazide 7 in dry xylene. Also, compound 6 react with CH(OEt)3 to give aminopyrimidine 9 which was reacted with arylidene malonodinitrile, furfural and/or dimethoxy-tetrahydrofuran to afford compounds 10, 11 and/or 12 respectively. Refluxing of 6 with CS2 gave oxadiazolylthienoquinoxaline 13, reaction of 13 with hyrazine hydrate, CH(OEt)3, nitrous acid, CS2 and a-halocompounds to give 14-19.

• 대한화학회지
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• 제60권6호
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• pp.457-461
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• 2016

• 대한화학회지
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• 제45권5호
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• pp.448-453
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• 2001

피라졸로아진은 농업이나 의약품에서 매우 유용한 화합물등이다. 본 논문에서는 몇 가지 새로운 피라졸로아진의 합성을 보고하고자 한다. 표제 화합물인 3-아미노-1H-피라졸-4-카복실산 에틸을 다이아조화한 후 활성화된 메틸렌 화합물들과 반응시키고 고리화하여 피라졸로[5,1-c][1,2,4]트라이아진 유도체들을 합성하였다. 또한 표제 화합물을 $\alpha$-치환된 신남나이트릴과 반응시켜 피라졸로[1,5-a]피리미딘 유도체들을 합성하였다. 새로 합성된 화합물들의 구조는 화학적 방법과 분광학적 방법을 사용하여 확립하였다.

• 대한화학회지
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• 제54권4호
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• pp.429-436
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• 2010

Guanine (1)으로부터 생물활성이 있는 halogenopurines계 화합물을 합성하였다. Guanine을 acetic anhydride와 반응시켜서 2,9-diacetylguanine (2-1)을 합성하여 얻어진 화합물을 $POCl_3$와 반응시켜서 화합물 3a를 합성하고, 다음 단계에서 2-amino-6-halogenopurines (3b-d)를 합성하였다. 2-Halogenopurines (2-2a-d, 4-2a-d, 5a-d)을 2-amino-6-substituted purines (1, 3a, 4-1)로부터 효율적으로 합성한 후에, 새로운 화합물인 2-2a, 2-2c, 2-2d, 4-2c, 4-2d, 5b, 5c 및 5d를 합성하였다. 합성한 화합물의 구조를 원소분석, $^1H$ NMR, mass spectral data로 확인하였으며, 합성한 화합물에 대한 항균 활성을 시험하였다.

• Fibers and Polymers
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• 제2권3호
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• pp.153-158
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• 2001

Nine disperse dyes have been synthesized by diazotization of 2-amino-4-(p-nitrophenyl)-5-nitrothiazole and coupled to substituted N-alkylanilines. Spectral properties in the IR and visible range of the dyes obtained were investigated. The dyeing performance of these dyes was assessed on nylon and polyester fibers. These dyes were found to give reddish brown to bluish violet shades on dyeing with very good depth, brightness and levelness on nylon and polyester fibers. The dyed fibers showed fairly good light fastness, very good to excellent fastness to wash, rubbing, perspiration and excellent fastness to sublimation. The dyebath exhaustion and fixation on the fiber were found to be very good.

• 대한화학회지
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• 제55권6호
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• pp.988-993
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• 2011

Cyclodehydration of 6-amino-5-cyano pyrimidine derivative (2) afforded pyrimidoisoindole derivatives (3). Compound (3) reacted with carbethoxymethylene derivative to give pyridopyrimidine derivatives (5a,b). Compound (3) was also reacted with formamide to give the corresponding pyrimidopyrimdine derivatives (6) that condensed with benzaldehyde to give Schiff's base (7). Refluxing of compound (3) with triethyl orthoformate afforded compound (8) that cyclized with ammonium hydroxide giving the same compound (6). Compound (8) cyclized with hydrazine hydrate giving compound (9) which also cyclized with triethyl orthoformate affording compound (10). Diazotization of compound (3) led to the formation of triazinopyrimidine derivative (11). Cyclization of compound (11) upon treatment with hydrazine hydrate afforded compound (12). Compound (15) was prepared from reaction of compound (3) and ethylenediamine in presence of carbon disulfide. The behaviour of compound (15) toward benzoyl chloride, triethyl orthoformate, nitrous acid and/or carbon disulfide was also described. All proposed structures were supported by elemental analyses, spectroscopic data and some of the new products showed antimicrobial activity.