• Title/Summary/Keyword: Diagnostic tests

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The Use of Confidence Interval of Measures of Diagnostic Accuracy (진단검사 정확도 평가지표의 신뢰구간)

  • Oh, Tae-Ho;Pak, Son-Il
    • Journal of Veterinary Clinics
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    • v.32 no.4
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    • pp.319-323
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    • 2015
  • The performance of diagnostic test accuracy is usually summarized by a variety of statistics such as sensitivity, specificity, predictive value, likelihood ratio, and kappa. These indices are most commonly presented when evaluations of competing diagnostic tests are reported, and it is of utmost importance to compare the accuracies of diagnostic tests to decide on the best available test for certain medical disorder. However, it is important to emphasize that specific point values of these indices are merely estimates. If parameter estimates are reported without a measure of uncertainty (precision), knowledgeable readers cannot know the range within which the true values of the indices are likely to lie. Therefore, when evaluations of diagnostic accuracy are reported the precision of estimates should be stated in parallel. To reflect the precision of any estimate of a diagnostic performance characteristic or of the difference between performance characteristics, the computation of confidential interval (CI), an indicator of precision, is widely used in medical literatures in that CIs are more informative to interpret test results than the simple point estimates. The majority of peer-reviewed journals usually require CIs to be specified for descriptive estimates, whereas domestic veterinary journals seem less vigilant on this issues. This paper describes how to calculate the indices and associated CIs using practical examples when assessing diagnostic test performance.

Diagnostic Hierarchy of Tic Disorders in Real-World Clinical Practice

  • Yeeji Sung;Soon-Beom Hong
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.34 no.4
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    • pp.236-241
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    • 2023
  • Objectives: According to the 10th revision of the International Classification of Diseases, the main categories of tic disorders (F95.0, F95.1, and F95.2) follow a diagnostic hierarchy based on the duration and diversity of tic symptoms. The present study investigated the use of this diagnostic hierarchy in real-world clinical practice. Methods: Based on the National Health Insurance Service-National Health Information Database, the diagnosis of transient tic disorder (F95.0) made after a diagnosis of chronic motor or vocal tic disorder (F95.1) or Tourette's syndrome (F95.2) and diagnosis of chronic motor or vocal tic disorder (F95.1) made after a diagnosis of Tourette's syndrome (F95.2) were referred to as type A errors. The diagnosis of transient tic disorder (F95.0) repeated after a period of >12 months was referred to as type B error. Demographic and clinical differences according to the diagnostic error types were analyzed using analysis of variance, Student's t-tests, and chi-squared tests. Results: Most participants (96.5%) were without errors in the diagnosis of tic disorders. Higher proportions of males (p=0.005) and antipsychotic prescriptions (p<0.001) were observed in patients with type A or B diagnostic errors. A higher proportion of health insurance holders was observed among those with type A errors (p=0.027). Conclusion: Errors were absent in majority of the tic diagnoses in real-world clinical practice in terms of the diagnostic hierarchy.

A Study on the Diagnostic Tests of the Internet Addiction Syndrome (인터넷 중독증 진단도구에 관한 연구)

  • Park, Ji-Whan
    • Journal of Korean Physical Therapy Science
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    • v.8 no.1
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    • pp.759-770
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    • 2001
  • The purpose of this study is through a analysis between old diagnostic tests of the Internet Addiction Syndrome to make a new test model for the physical disturbance problems for the addiction persons. Suggestion treatment for the Internet Addiction Syndrome are follows: 1. Try to decide in advance how much time you will spend on the Net time a day. 2. Decide how much you want the Internet to be a part of each area of your life and then allocate time accordingly. 3. You may decide that you want to keep the Internet at work, and shut the door on it when you leave for home. 4. To physical exercise regularly. 5. Take frequent breaks. 6. Seek out friends and acquaintances who couldn't care less about the Internet. 7. Interact with people in a non-wired world. 8. Consult a Dr. if you can't solved.

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Characteristics of Accelerated Aging in Generator Stator Windings (발전기 고정자 권선의 가속열화 특성)

  • Kim, Hee-Dong;Kong, Tae-Sik;Ju, Young-Ho
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.06a
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    • pp.279-280
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    • 2008
  • Accelerated aging tests were conducted under laboratory conditions on two generator stator bars. Electrical stress is applied in No. 1 model stator bar. Electrical and thermal stresses are applied in No. 2 model stator bar. As aging times increased from 0 to 4780h, diagnostic tests were performed on No. 1 and No. 2 model stator bars. Diagnostic tests included AC current, dissipation factor(tan$\delta$) and partial discharge magnitude. The ${\Delta}tan{\delta}$ and $\Deta$I of No. 1 and No. 2 model stator bars increased with increased in aging time.

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Diagnostic Value of Immunoglobulin G Anti-Deamidated Gliadin Peptide Antibody for Diagnosis of Pediatric Celiac Disease: A Study from Shiraz, Iran

  • Anbardar, Mohammad Hossein;Haghighi, Fatemeh Golbon;Honar, Naser;Zahmatkeshan, Mozhgan
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.25 no.4
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    • pp.312-320
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    • 2022
  • Purpose: Screening serologic tests are important tools for the diagnosis of celiac disease (CD). Immunoglobulin (Ig)G anti-deamidated gliadin peptide (anti-DGP) is a relatively new autoantibody thought to have good diagnostic accuracy, comparable to that of anti-tissue transglutaminase (anti-tTG) antibody. Methods: Pediatric patients (n=86) with a clinical suspicion of CD were included. Duodenal biopsy, anti-tTG, and IgG anti-DGP antibody tests were performed. The patients were divided into CD and control groups based on the pathological evaluation of duodenal biopsies. The diagnostic accuracy of serological tests was determined. Results: IgA anti-tTG and IgG anti-DGP antibodies were positive in 86.3% and 95.4% of patients, respectively. The sensitivity, specificity, and diagnostic accuracy of the IgA anti-tTG test were 86.3%, 50.0%, and 68.6%, respectively, and those of the IgG anti-DGP test were 95.4%, 85.7%, and 90.7%, respectively. The area under the receiver operating characteristic (ROC) curve was 0.84 (95% confidence interval [CI], 0.74-0.91) for IgA anti-tTG test and 0.93 (95% CI, 0.86-0.97) for IgG anti-DGP test. The comparison of IgA anti-tTG and IgG anti-DGP ROC curves showed a higher sensitivity and specificity of the IgG anti-DGP test. Conclusion: IgG anti-DGP is a reliable serological test for CD diagnosis in children. High tTG and DGP titers in the serum are suggestive of severe duodenal atrophy. The combined use of IgA anti-tTG and IgG anti-DGP tests for the initial screening of CD can improve diagnostic sensitivity.

Evaluation of Insulation Diagnostic Test Reliability for Stator Winding of High Voltage Induction Motor (고압유도전동기 절연특성시험의 신뢰도 평가)

  • Lee, Kwang-Ho;Kim, Hyun-Il;Kwak, Hee-Jin;Oh, Bong-Keun
    • Proceedings of the KIEE Conference
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    • 2004.07c
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    • pp.1838-1841
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    • 2004
  • This test was performed to assess the correlation between insulation diagnostic tests and breakdown voltage strength of the stator winding of 6.6kV class induction motor in insulation deterioration condition which have been in service for 5 years after being installed in 1998. The insulation diagnostic tests include resistance, polarization index(P.I), dissipation factor(${\triangle}tan{\delta}$), maximum partial discharges(Qmax) and AC breakdown test. we evaluated the correlation between insulation diagnostic test and AC breakdown test for stator winding of high voltage induction motor.

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Multi-facet Analysis on Validity of Sasang Type Diagnostic Test (사상체질 진단검사 타당성 분석에 대한 연구)

  • Lee, Soo-Jin;Kim, Myoung-Geun;Chae, Han
    • The Journal of Korean Medicine
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    • v.29 no.1
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    • pp.7-14
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    • 2008
  • Purpose : The purpose of study was to develop generalized validity evaluation methods and terms for Sasang type diagnostic tests. Methods : A generalized statistical evaluation model for Sasang typology was suggested and generalized validity evaluation indices were proposed with this model. Results : The usefulness of validity evaluations, such as sensitivity and specificity values, were confirmed by the systematic review of the data from previously reported studies. Conclusion :Major obstacles in the multi-facet analysis and systematic review for Sasang type diagnostic tests were discussed with this test validity study.

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Evaluation of Insulation Diagnostic Test Reliability for Stator Winding of High Voltage Induction Motor (고압유도전동기 절연특성시험의 신뢰도 평가)

  • Lee, Kwang-Ho;Kim, Hyun-Il;Kwak, Hee-Jin;Oh, Bong-Keun
    • Proceedings of the KIEE Conference
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    • 2004.11d
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    • pp.46-49
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    • 2004
  • This test was performed to assess the correlation between insulation diagnostic tests and breakdown voltage strength of the stator winding of 6.6kV class induction motor in insulation deterioration condition which have been in service for 5 years after being installed in 1998. The insulation diagnostic tests include resistance, polarization index(P.I), dissipation factor(${\Delta}tan{\delta}$). maximum partial discharges(Qmax) and AC breakdown test. we evaluated the correlation between insulation diagnostic test and AC breakdown test for stator winding of high voltage induction motor.

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Assessment of Insulation Deterioration in Stator Windings of High Voltage Motor (고압전동기 고정자 권선의 절연열화 평가)

  • Kim, Hee-Dong;Kong, Tae-Sik
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.61 no.5
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    • pp.711-716
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    • 2012
  • To assess the insulation deterioration of stator windings, diagnostic and AC breakdown tests were performed on the eleven high voltage (HV) motors rated at 6kV. After completing the diagnostic tests, the AC overvoltage test was performed by gradually increasing the voltage applied to the stator windings until electrical insulation failure occurred, to obtain the breakdown voltage. Stator winding of motors 1, 3, and 8 failed at above rated voltage at 14 kV, 13.8kV, and 16.4kV, respectively. The breakdown voltage of three motors was higher than expected for good quality windings in 6kV motors. Based on deterioration evaluation criteria, the stator winding insulation of eleven HV motors are confirmed to be in good condition. The turning point of the current, $P_{i2}$, in the AC current vs. voltage characteristics occurred between 5kV and 6kV, and the breakdown voltage was low between 13.8kV and 16.4kV. There was a strong correlation between the breakdown voltage and various electrical characteristics in diagnostic tests including Pi2.

Comparative analysis of serological tests and fecal detection in the diagnosis of Mycobacterium avium subspecies paratuberculosis infection

  • Park, Hong-Tae;Ha, Seungmin;Park, Hyun-Eui;Shim, Soojin;Hur, Tai Young;Yoo, Han Sang
    • Korean Journal of Veterinary Research
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    • v.60 no.3
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    • pp.117-122
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    • 2020
  • Johne's disease (JD) caused by Mycobacterium avium subspecies paratuberculosis (MAP) is a chronic, wasting infectious disease in ruminants that causes enormous economic losses to the dairy and beef cattle industries. The most effective way to eradicate JD is to detect infected individuals as early as possible and remove them from the herd. However, it is difficult to detect infected individuals early with the currently using diagnostic methods. Two serological diagnostic kits commercially used worldwide and a fecal detection test were compared using 298 serum samples and feces of cattle in this study to present an efficient diagnostic method. Although there was a high correlation between the 2 serological diagnostic kits (R2 = 0.7473), kit A showed a higher serological positive rate. However, the correlation between fecal tests and serological diagnosis was very low. MAP was also detected in fecal tests in many serologically negative individuals. In the periodical diagnosis of JD, MAP was detected in the feces of only cows with the higher antibody titer to MAP. These results suggest that for effective eradication of JD, early detection of infected individuals by fecal tests together with the serological tests currently in use and by removal of infected individuals are needed.