• 제목/요약/키워드: Diagnostic tests

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Autonomic dysfunction in patients with orthostatic dizziness

  • Hyung Lee;Hyun Ah Kim
    • Annals of Clinical Neurophysiology
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    • v.25 no.1
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    • pp.27-31
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    • 2023
  • Orthostatic dizziness is feeling dizzy or lightheaded when standing up. Hemodynamic orthostatic dizziness can be caused by autonomic dysfunction such as orthostatic hypotension or postural tachycardia syndrome. The interpretation of the autonomic function test results in patients with orthostatic dizziness is crucial for diagnosing and managing the underlying condition. The head-up tilt and Valsalva tests are especially important for evaluating adrenergic function in patients with hemodynamic orthostatic dizziness. However, it is important to note that autonomic function tests do not cover the entire diagnostic process, since their findings need to be considered along with the detailed history and physical examination results of the patient because various differential diagnoses exist for orthostatic dizziness. Ensuring appropriate treatment by interpreting the autonomic function test results can help to determine the improvement of and prevents falls from orthostatic dizziness.

Ebstein anomaly, right-to-left atrial septal defect, and cor triatriatum dexter in a cat: a case report

  • Soolyi Park;Wonseok Oh;Daye Lee;Seunggon Lee
    • Korean Journal of Veterinary Research
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    • v.64 no.1
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    • pp.5.1-5.6
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    • 2024
  • A 6-month-old male Ragdoll cat presented with exercise intolerance. On physical examination, there was a grade 2/6 systolic murmur at the right apex. Diagnostic tests, including SpO2 measurement, blood tests, radiography, echocardiography, contrast echocardiography, and electrocardiography, were performed. Severe right atrial dilation, tricuspid valve leaflets and orifice displacement, right ventricular atrialization, septal leaflet adherence, anterior leaflet tethering, and right atrioventricular junction dilation were noted on echocardiography, alongside a right-to-left atrial septal defect. Cor triatriatum dexter and left ventricular aneurysm were observed. We diagnosed this case as having Ebstein anomaly with rare congenital heart deformities; which is rare in cats.

Clinical Significance and Interpretation of Allergen-Specific IgE Testing in Regard to Food Allergy (식품 알레르기에서 특이 IgE 검사의 유용성 및 해석)

  • Hyun Jung Jin
    • The Korean Journal of Medicine
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    • v.99 no.3
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    • pp.145-148
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    • 2024
  • Food allergy is an adverse reaction that occurs after ingesting food and is caused by an aberrant immune response. Taking a detailed medical history is the most important part of diagnosing food allergies. When an immunoglobulin E (IgE)-mediated food allergy is suspected, food-specific IgE testing can confirm the diagnosis. Allergen skin-prick tests or serum tests for specific IgE should be considered as the first line of testing, and depending on the offending food, a further prick-to-prick test with fresh food or a component-resolved diagnostic test may be helpful. Interpretation of the results should be based on the patient's medical history.

Comparison between indirect immunofluorescent antibody (IFA) test and enzyme-linked immunosorbent assay (ELISA) for the detection of antibody to porcine reproductive and respiratory syndrome virus(PRRSV) (돼지 생식기호흡기증후군 바이러스항체 검색에 있어 간접형광항체법(IFA) 과 효소면역법(ELISA)의 진단효율 비교)

  • Park, Choi-kyu;Lyoo, Young-soo;Lee, Chang-hee;Jung, Jong-wook
    • Korean Journal of Veterinary Research
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    • v.38 no.2
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    • pp.314-318
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    • 1998
  • An establishment of effective control measures to PRRSV infection in swine industry depends on a sensitive and specific diagnosis to detect either viral antigen and/or antibodies to PRRSV. Several diagnostic methods are available to detect antibodies against PRRSV, including IPMA, IFA and ELISA tests have been successfully developed. Sensitivity of the indirect immunofluorescent assay in MA-104 cells using Korean field isolate PL96-1 was superior to that of VR-2332 and field isolate PL96-2. Sensitivity and specificity of the IFA test with PL96-1 were comparable to those of commercial ELISA test kit but ELISA test was more sensitive for the detection of declining antibodies to PRRSV in finishing pigs. In this study we concluded that IFA and ELISA test could be utilized to detect antibodies to PRRSV and the results generated from these two tests were comparable and there were no significant difference between these two tests.

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Girder Distribution Model for Existing Short and Medium Span Steel Girder Bridges (단·중경간 강형교 거더의 횡분배 모델)

  • Eom, Jun-Sik;Nowak, Andrzej S.;Lho, Byeong-Cheol
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.7 no.2
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    • pp.219-229
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    • 2003
  • The objective of this work is to verify the Code specified girder distribution factors for short and medium span bridges. To accomplish this objective, field tests were carried out on seventeen simply supported highway bridges. This paper presents the procedure and results of field tests that were performed to verify girder distribution factors. Finite Element analyses previously performed at the University of Michigan indicated that in most cases currently used girder distribution factors specified in AASHTO Codes are too conservative. However, these studies also showed that for short spans and short girder spacings, the girder distribution factors can be too permissive. Therefore, this paper focused on experimental evaluation of girder distribution factors for short and medium span steel girder bridges. The results were compared with the distribution factors specified by AASHTO Standard (2000) and AASHTO LRFD Code (1998). It has been found that the measured girder distribution factors are lower than AASHTO values in most cases, and sometimes the code specified values are overly conservative. The research work involved formulation of the testing procedure, selection of structure, installation of equipment, measurements, and interpretation of the results.

Updates on the Diagnosis of Helicobacter pylori Infection in Children: What Are the Differences between Adults and Children?

  • Yang, Hye Ran
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.19 no.2
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    • pp.96-103
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    • 2016
  • Helicobacter pylori infection is acquired mainly during childhood and causes various diseases such as gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue (MALT) lymphoma, and iron deficiency anemia. Although H. pylori infection in children differs from adults in many ways, this is often overlooked in clinical practice. Unlike adults, nodular gastritis may be a pathognomonic endoscopic finding of childhood H. pylori infection. Histopathological findings of gastric tissues are also different in children due to predominance of lymphocytes and plasma cells and the formation of gastric MALT. Although endoscopy is recommended for the initial diagnosis of H. pylori infection, several non-invasive diagnostic tests such as the urea breath test (UBT) and the H. pylori stool antigen test (HpSA) are available and well validated even in children. According to recent data, both the $^{13}C$-UBT and HpSA using enzyme-linked immunosorbent assay are reliable non-invasive tests to determine H. pylori status after eradication therapy, although children younger than 6 years are known to have high false positives. When invasive or noninvasive tests are applied to children to detect H. pylori infection, it should be noted that there are differences between children and adults in diagnosing H. pylori infection.

A Study for Identifying Language Impairment in Preschooler (학령전기 아동언어장애 진단을 위한 조사연구)

  • Sehr, Kyoung-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.1
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    • pp.194-198
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    • 2013
  • A total of 193 children between three and six years of age were given tests by using the PRES, REVT, KOSECT, and APAC. A specificity between referred and non-referred cases was not high. In the current study, the sensitivity of formal tests was insufficient. But combining of parental report with formal language tests could provide good criteria for identifying language impairment. The CCC-2 may provide an effective means to identify language difficulties using a standardized approach.

The Usefulness of Blink Reflex in the Evaluation of Early Stage of Bell's Palsy (발병초기 벨마비 환자의 진단에서 순목 반사(blink reflex)의 유용성)

  • Seok, Jung Im;Lee, Dong Kuck;Kim, Chang-Hyeong
    • Annals of Clinical Neurophysiology
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    • v.14 no.1
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    • pp.25-28
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    • 2012
  • Background: Bell's palsy is the most common disease of cranial nerve. While most electrodiagnostic tests can detect the abnormality of facial nerve several days later in Bell's palsy, blink reflex usually reveals the abnormality earlier than other tests. Therefore, we investigated the diagnostic usefulness of blink reflex in the early stage of Bell's palsy. Methods: We performed a prospective investigation in patients with facial palsy. We enrolled patients with Bell's palsy who were evaluated within 7 days of symptom onset and excluded patients with secondary causes of facial palsy. We analyzed the findings of blink reflex according to age, sex, evaluation time, and severity of facial palsy. Results: Of 320 consecutive patients with facial palsy, a total of 204 patients were enrolled. Blink reflex was normal for 10 patients and abnormal for 194 patients. The time interval between the symptom onset and the evaluation time was not associated with the result of blink reflex, but House-Brackmann grade was significantly related to the result of blink reflex (P<0.001). Patients with mild Bell's palsy often showed normal blink reflex. Conclusions: Our study shows that blink reflex is useful diagnostic test regardless of evaluation timing in the early stage of Bell's palsy, although it could be normal in patients with mild Bell's palsy.

CARIES DIAGNOSIS BY DIAGNODENT'S LASER FLUORESCENCE DETECTION IN VITRO (레이저형광측정을 통한 Diagnodent의 우식진단에 관한 생체외 연구)

  • Kim, Seong-Hyeong;Lee, Kwang-Hee;Kim, Dae-Eop;Park, Jong-Seok
    • Journal of the korean academy of Pediatric Dentistry
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    • v.27 no.1
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    • pp.24-31
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    • 2000
  • The purpose of study was to compare the laser fluorescence detection by Diagnodent(KaVo, Germany), visual inspection using dental explorers, and conventional dental radiography as diagnostic tests for dental caries. One hundred and three human premolars and molars which had no caries or fissure caries were tested by the three methods. Diagnodent scores increased as the scores of the other two tests increased(P<0.01) There were significant relationships between visual inspection scores and Diagnodent scores(Pearson 0.676, Spearman 0.694) and between radiography scores and Diagnodent scores(Pearson 0.623, Spearman 0.658) (P<0.01, all). Diagnodent test proved to have high sensitivity and low specificity and more studies are necessary to present the diagnostic criteria for progressive caries stages.

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Diagnostic Significance of Cold Agglutinin and Antimycoplasma Antibody for Mycoplasma pneumoniae Infection (항Mycoplasma 항체와 한냉응집소에 의한 Mycoplasma pneumoniae의 진단학적 의의)

  • Kim, Chung-Sook;Lee, Chae-Hoon;Jeon, Chang-Ho;Bae, Eun-Kyung;Hong, Seak-Il
    • Journal of Yeungnam Medical Science
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    • v.4 no.1
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    • pp.97-103
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    • 1987
  • A Study to evaluate the diagnostic significance of M. pneumoniae infection by measurements of cold agglutinin and antimycoplasma antibody titers is performed with 191 pediatric patients who have visited Yeungnam University Hospital during the period through January to July, 1987. Forty eight of 191 cases made follow up tests feasible. The results obtained are as follows : 1. It is necessary to perform routine combined measurements of cold agglutinin and antimycoplasma antibody titers for the all pediatric pneumoniae caser since a large proportion of pneumonia in children is caused by M. pneumoniae. 2. For the diagnosis of M. pneumoniae infection, measurements of cold agglutinin titers alone seems to be les significant than to check both cold agglutinin and antimycoplasma antibody titers. 3. The measurement of antimycoplasma antibody titer appeared to be more specific than cold agglutinin test in the diagnosis of M. pneumoniae infection. 4. The present study urges the necessity of follow up study of cold agglutinin and antimycoplasma antibody titers for those who initially presented with normal titers in both tests, but are clinically suspected for M. pneumoniae infection.

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