• Title/Summary/Keyword: Diagnostic Prediction

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The Difference of Predictor of Bone Mineral Density in Pre and Postmenopausal Women (폐경에 따른 골밀도 예측인자의 차이)

  • Kim, Mi-Young;Kim, Hwa-Sun
    • Journal of radiological science and technology
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    • v.34 no.3
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    • pp.195-201
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    • 2011
  • We studied the relationship between prediction parameters and bone mineral density for pre-and-post menopausal women. We measured BMI%Fat by BIA, blood pressure and lipid profiles for 483 adult women who are in NPO state. SBP, TC, TG, LDL have significant statistical value in the postmenopause women group and postmenopause woman. The value of postmenopause women of these parameters are lower than premenopause woman. BMD has the most strongest relationship with LBM. The BMD and LDL level of postmenopause women have statistically negative relationship. The results show that for the premenopause cases, weight, BF, and HDL level were the major factors which affect the BMD. For postmenopause cases, however, weight, age, and LDL level turned out to be the most significant factors.

A cognitive model for forecasting progress of multiple disorders with time relationship

  • Kim, Soung-Hie;Park, Wonseek;Chae, In-Ho
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 1996.04a
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    • pp.505-510
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    • 1996
  • Many diseases cause other diseases with strength of influences and time intervals. Prognostic and therapeutic assessments are the important part of clinical medicine as well as diagnostic assessments. In cases where a patient already has manufestations of multiple disorders (complications), progress forecasting and therapy decision by physicians without support tools are very dificult: physicians often say that "Once complications set in, the patient may die". Treating complications are difficult tasks for physicians, because they have to consider all of the complexities, possibilities and interactions between the diseases. The prediction of multiple disorders has many bundles that arise from such time-dependent interrelationships between diseases and nonlinear progress. This paper proposes a model based on time-dependent influences, which appropriately describes the progress of mulitple disorders, and gives some modificaitons for applying this model to medical domains: time-dependent influence matrix manifestation vector, therapy efficacy matrix, S-shaped curve approximation, definitions of which are provided. This research proposes an algorithm for forecasting the state of each disease on the time horizon and for evaluation of therapy alternatives with not toy example, but real patient history of multiple disorders.disorders.

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Studies on the Pregnancy Diagnosis from Monoclonal Antigen of Progesterone (Progesterone Monoclonal Antigen에 의한 임신진단에 관한 연구)

  • ;Ono Hitoshi
    • Korean Journal of Animal Reproduction
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    • v.11 no.2
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    • pp.132-138
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    • 1987
  • This study was carried out to evaluate the ability of clinical application of pregnancy diagnosis based upon the determinatin of progesterone in milk, utilizing a chymosin inhibitor labelled with progesterone and monoclonal antibody to progesterone, and its compared with progesterone concentrations in the milk were assayed by radioimmunoassay. 1. The progesterone concentration of the pregnant cows (2.07$\pm$0.54ng/ml) were significantly higher than those of non-pregnant cows (1.04$\pm$0.19 ng/ml), and thereafter began to increase and maintained high levels. 2. During 20 to 22 days after artificial insemination, the accuracy of pregnancy diagnosis from monoclonal antigen of progesterone were 92.9% for non-pregnant cows, and 88.5% for pregnant cows. 3. During 20 to 22 days after artificial inseminatin, the accuracy of pregnancy diagnosis from milk progesterone concentrations were 92.9% for non-pregnant cows(<3.4ng/ml), and 92.3% for pregnant cows( 4.0ng/ml). The average overall accuracy of pregnancy prediction for pregnant and non-pregnant cows were 92.6%. 4. Accordingly, the pregnancy diagnosis from monoclonal antigen of progesterone is thought to be recommendable because this early diagnostic means are simple with accurate result.

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The Study on tree growth in XLPE using PD patterns (부분방전 패턴을 이용한 가교폴리에틸렌에서의 트리성장에 관한 연구)

  • Kang, Dae-Yong;Wu, Guangning;Shin, Chang-Myon;Park, Myoung-Seop;Cho, Kyu-Bock;HwangBo, Seung;Park, Dae-Hee
    • Proceedings of the KIEE Conference
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    • 1998.11c
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    • pp.941-943
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    • 1998
  • Exploitation of equipment with cross linked polyethylene (XLPE) insulation requires its condition monitoring and diagnostic. Traditionally diagnostics of insulation is carried out by means of partial discharge detection. Many researchers have developed a lot of methods to identify the defect by the PD form. However, such identification of a defect, for example, void, inclusion or treeing, does not say about its danger from a point of view of full insulation gap breakdown and insulation construction failure. The information about the form and size of formed upon high voltage treeing is necessary for prediction of the remained resource of XLPE insulation. For this purpose we carry out experimental research for determination of the dependencies between PD characteristics in XLPE upon time and three dimension PD patterns of corresponding treeing. The investigations were carried out by means of electrical measurement of PD current and simultaneous optical recording of treeing image. Test results show that the PD patterns can be applied for detecting tree growth well.

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Aberrant Methylation of RASSF1A gene Contribute to the Risk of Renal Cell Carcinoma: a Meta-Analysis

  • Yu, Gan-Shen;Lai, Cai-Yong;Xu, Yin;Bu, Chen-Feng;Su, Ze-Xuan
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.11
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    • pp.4665-4669
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    • 2015
  • The aim of this study was to assess the diagnostic value of RASSF1A methylation in renal cell carcinoma. Systematically search were performed using the Pubmed, ProQest and Web of Science for all articles on the association between RASSF1A methylation and renal cell carcinoma before 15 April 2015. After the filtration, 13 studies involving 677 cases and 497 controls met our criteria. Our meta-analysis suggested that hypermethylation of RASSF1A gene was associated with the increased risk of RCC(OR:4.14, 95%CI:1.06-16.1). Stratified analyses showed a similar risk in qualitative detection method(OR:28.4, 95%CI:10.2-79.6), body fluid sample(OR:12.8, 95%CI:5.35-30.8), and American(OR:10.5, 95%CI:1.97-55.9). Our result identified that RASSF1A methylation had a strong potential in prediction the risk of Renal cell carcinoma.

A Study on Sensor Module and Diagnosis of Automobile Wheel Bearing Failure Prediction (차량용 휠 베어링의 결함 예측을 위한 센서 모듈 및 진단 연구)

  • Hwang, Jae-Yong;Seol, Ye-In
    • Journal of the Korea Convergence Society
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    • v.11 no.11
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    • pp.47-53
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    • 2020
  • There is a need for a system that provides early warning of presence and type of failure of automobile wheel bearings through the application of predictive fault analysis technologies. In this paper, we presented a sensor module mounted on a wheel bearing and a diagnostic system that collects, stores and analyzes vehicle acceleration information and vibration information from the sensor module. The developed sensor module and predictive analysis system was tested and evaluated thorough excitation test equipment and real automotive vehicle to prove the effectiveness.

Clinical Application of $^{18}F-FDG$ PET in Cervix Cancer (자궁경부암에서 $^{18}F-FDG$ PET의 임상 이용)

  • Oh, So-Won;Kim, Seok-Ki
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.sup1
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    • pp.101-109
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    • 2008
  • Cervix cancer is one of common gynecological cancers in the world, and staged with FIGO or TNM system. However, these clinical staging systems lack information about lymph node or distant metastases, thus imaging modalities are considered to make an appropriate therapeutic plan and enhance overall survival rate. In this context, FDG PET is recommended to pre-treatment stating and prognosis prediction, for it could noninvasively evaluate the status of lymph nodes, especially abdominal paraaortic nodes which are closely related with prognosis. Moreover, the degree of FDG uptake is correlated with prognosis. Although there is no consistent method for surveillance of cervix cancer, FDG PET seems a very important tool in detecting tumor recurrence because it is much more advantageous than conventional imaging modalities such as MRI for discerning recurrent tumor from fibrosis caused by radiation or surgery. Furthermore, FDG PET could be used to evaluate treatment response. On the other hand, recently introduced PET/CT is expected to play an ancillary role to FIGO staging by adding anatomical information, and enhance diagnostic performance of PET by decreasing false positive findings.

Interferon Induced Transmembrane Protein-1 Gene Expression is a Biomarker for Early Detection of Invasive Potential of Oral Squamous Cell Carcinomas

  • Ramanathan, Arvind
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.2297-2299
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    • 2016
  • Background: Early detection of malignant transformation with expression biomarkers has significant potential to improve the survival rate of patients as such biomarkers enable prediction of progression and assess sensitivity to chemotherapy. The expression of interferon inducible transmembrane protein 1 (IFITM1) has been associated with early invasion events in several carcinomas, including head and neck cancers, and hence has been proposed as a novel candidate biomarker. As the incidence of oral squamous cell carcinoma (OSCC) is highest in the Indian population, we sought to investigate: 1) the expression pattern of IFITM1 in OSCC tissue samples obtained from Indian patients of Dravidian origin; and 2) the possibility of using IFITM1 expression as a potential biomarker. Materials and Methods: Total RNA extracted from thirty eight OSCC biopsy samples was subjected to semi-quantitative RT-PCR with IFITM1 and GAPDH specific primers. Results: Of the thirty eight OSCC samples that were analyzed, IFITM1 overexpression was identified in fifteen (39%). Seven expressed a low level, while the remainder expressed high level of IFITM1. Conclusions: The overexpression of IFITM1 in OSCC samples indicates that IFITM1 may be explored for the possibility of use as a high confidence diagnostic biomarker in oral cancers. To the best of our knowledge, this is the first time that IFITM1 overexpression is being reported in Indian OSCC samples.

A Study on Trouble Management and Necessity for Preventive Check in PACS

  • Son, Gi-Gyeong;Sung, Dong-Wook;Shin, Jin-Ho;Jeong, Jae-Ho;Kang, Hee-Doo
    • Korean Journal of Digital Imaging in Medicine
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    • v.8 no.1
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    • pp.39-43
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    • 2006
  • PACS has been run at the Kyung Hee University Medical Center since 2001, and the installation and operation of PACS have contributed to automation and quantification of center's medical environment. In order to classify tile annual number of trouble cases processed by PACS, the authorshave made a classification code system which enabled detailed statistical processes for each section. Such process method has not only shown the management efficiency to trouble management of PACS, but also raised the interests in frequently occurring troubles, and enabled the prediction of troubles that may occur hereafter. Predictable troubles lead to preventive check, and this has direct effects on medical treatment and the hospital administration. The authors intend to arouse the necessity of preventive check of PACS by analyzing trouble management processes for the last 1 year.

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Towards developing a diagnostic regimen for the treatment follow-up of Trypanosoma brucei gambiense

  • Mbati, Peter-A.;Hirumi, Kazuko;Inoue, Noboru;Situakibanza, Nanituma-H.;Hirumi, Hiroyuki
    • Parasites, Hosts and Diseases
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    • v.37 no.4
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    • pp.289-292
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    • 1999
  • BALB/c mice infected with a high virulent strain of Trypanosoma brucei gambiense IL3707 were treated intraperitoneally (ip) with either Melarsoprol (Mel-B) or PSG(+) buffer as controls. The mice were subsequently monitored regularly for parasites by direct microscopic examination of their tail blood or buffy coat and by polymerase chain reaction (PCR). Mel-B was found to be an effective drug for treatment against T.b. gambiense because at the end of the first treatment schedule, all treated mice were negative for parasites even by PCR, while all the control animals were positive. Three of the five Mel-B treated mice, while parasitologically negative, were PCR positive between 53 and 80 days post infection (DPI), indicating that they still harbored an infection. All treated mice were subsequently negative for parasites even by PCR at 88 DPI. A combination of conventional microscopic examination and PCR offers a good prediction of cure following treatment of trypanosomosis.

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