• 제목/요약/키워드: Diagnostic Evaluation

검색결과 1,587건 처리시간 0.027초

구강 악안면 영역의 암종 진단에 있어서 $[^{18}F]$-Fluorodeoxyglucose를 이용한 양전자방출 단층촬영의 임상적 연구 (CLINICAL STUDY OF POSITRON EMISSION TOMOGRAPHY WITH $[^{18}F]$-FLUORODEOXYGLUCOSE IN MAXILLOFACIAL TUMOR DIAGNOSIS)

  • 김재환;김경욱;김용각
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제26권5호
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    • pp.462-469
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    • 2000
  • Positron Emission Tomography(PET) is a new diagnostic method that can create functional images of the distribution of positron emitting radionuclides, which when administered intravenously in the body, makes possible anatomical and functional analysis by quantity of biochemical and physiological process. After genetic and biochemical changes in initial stage, malignant tumor undergoes functional changes before undergoing anatomical changes. So, early diagnosis of malignant tumors by functional analysis with PET can be achieved, replacing traditional anatomical analysis, such as computed tomography(CT) and magnetic resonance image(MRI), etc. Similarly, PET can identify malignant tumor without confusion with scar and fibrosis in follow up check. In the Korea Cancer Center Hospital(KCCH) from October 1997 to September 1999, clinical study was performed in 79 cases that underwent 89 times PET evaluation with [18F]-Fluorodeoxyglucose for diagnosis of oral and maxillofacial tumors, and the data was analysed by Bayesian $2{\times}2$ Classification Table. The results were as follows : Evaluation for initial diagnosis with FDG-PET (P<0.005) 1. Agreement rate or accuracy rate is 88.9%. 2. Sensitivity is 95.2%, and specificity 66.7%. 3. Positive predictive rate is 90.9%, and negative predictive rate 80.0%. 4. In consideration of tumor stage, diagnostic rate in less than stage II was 90% and in greater than stage III 100%. 5. In consideration of tumor size, diagnostic rate in less than T2 was 92.3% and in greater than T3 100%. After primary treatment, evaluation for follow up check with FDG-PET (P < 0.001) 1. Agreement rate or accuracy rate is 85.4%. 2. Sensitivity is 87.5%, and specificity 82.4%. 3. Positive predictive rate is 87.5%, and negative predictive rate 82.4%. 4. In 24 recurred cases, 6 had distant metastasis, and 5 of them were diagnosed with FDG-PET, resulting in diagnostic rate of FDG-PET of 83.3%. From the above results, Positron Emission Tomography with [18F]- Fluorodeoxyglucose appears to be more sensitive and accurate for detecting the presence of oral and maxillofacial tumors, and has various clinical applications such as early diagnosis of tumor in initial and follow up check and detection of distant metastasis.

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설갑상선(舌甲狀腺)의 1례(例) (A Case of Lingual Thyroid)

  • 이경자
    • 대한핵의학회지
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    • 제3권1호
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    • pp.101-105
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    • 1969
  • A case of lingual thyroid in 10 years old girl is presented with the use of radioactive iodine ($^{113}I$) and the scintigram for the diagnostic evaluation. A brief review of literature on the incidence, etiology and-development, symptomatology, diagnosis, and treatment of the lingual thyroid was done.

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Comprehensive review of membranoproliferative glomerulonephritis: spotlighting the latest advances in revised classification and treatment

  • Jeong Yeon Kim
    • Childhood Kidney Diseases
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    • 제27권2호
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    • pp.64-69
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    • 2023
  • Membranoproliferative glomerulonephritis (MPGN) is a complex group of renal diseases characterized by a specific pattern of glomerular injury that includes thickening of the capillary wall and mesangial expansion, leading to a heterogeneous group of conditions. This review article offers a comprehensive overview of MPGN, its new classification, pathophysiology, diagnostic evaluation, and management options.

Applying the ACR Preliminary Diagnostic Criteria in the Diagnosis and Assessment of Fibromyalgia

  • Kim, So-Mi;Lee, Sang-Heon;Kim, Hae-Rim
    • The Korean Journal of Pain
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    • 제25권3호
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    • pp.173-182
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    • 2012
  • Background: Fibromyalgia (FM) is characterized by chronic widespread pain with a low pain threshold. The aim of this study was to compare two criteria for the diagnosis and assessment of FM and to analyze the correlation and agreement between the 1990 and 2010 American College of Rheumatology (ACR) preliminary diagnostic criteria for FM. Methods: We studied 98 patients who had already been diagnosed as having FM using the 1990 criteria or 2010 preliminary criteria. Tender point examination, FM impact questionnaire (FIQ) and pain visual analog scale (VAS) were obtained. According to the preliminary criteria, FM was quantified as WPI (widespread pain index) and the SS scale (symptom severity) and the two criteria were compared. Results: Among 98 patients, 78.6% of the patients were diagnosed with the 1990 ACR criteria and 93.9% of the patients were diagnosed with the ACR preliminary diagnostic criteria, and there was also significant agreement between the two criteria (P < 0.01). There was a correlation with the WPI and the tender point, with the SS and the FIQ, and with the sum of the WPI and SS and the FIQ. Conclusions: The ACR preliminary diagnostic criteria for FM were in agreement with the 1990 ACR criteria during the disease course. The preliminary criteria were the more sensitive method than the 1990 criteria. In addition, the 2010 criteria might have advantages since it is easy to assess the physical and psychological symptoms and can be quantified. Therefore, the ACR preliminary diagnostic criteria for FM could be used more conveniently for clinical diagnosis and follow up evaluation after starting management of FM.

갑상선 촉지 종괴에서 시행한 세침흡인세포검사법, 동결절편검사법 및 초음파검사법의 진단적 유용성 (Diagnostic Efficacy of Fine Needle Aspiration Cytology, Frozen section Biopsy and Ultrasonography for a Palpable Thyroid Mass)

  • 이병길;정성후
    • 대한두경부종양학회지
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    • 제18권2호
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    • pp.168-172
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    • 2002
  • Objectives: This study was done to determine the diagnostic efficacy of fine needle aspiration cytology (FNA), frozen section biopsy (FSx) and ultrasonography in a palpable thyroid mass. Materials and Methods: During the period from July 1999 to March 2002, the medical records of 98 patients who underwent a thyroidectomy for thyroid mass, at the Department of Surgery, Chonbuk National University Hospital, were reviewed retrospectively. Ninety eight cases were classified according to whether the FNA cytological diagnosis inadequate, benign, suspicious, or malignant and the FSx diagnosis benign or malignant and the ultrasonographic examination was benign, suspicious, or malignant. The diagnostic correlations of ultrasonography, FNA cytology, frozen section, and both FNA cytology and frozen section with definite histologic diagnosis were evaluated. Results: According to the FNA cytological interpretation, 76 cases were diagnosed as benign, 6 cases suspicious, 13 cases malignant, and 3 cases inadequate. The sensitivity and specificity for FNA were 86.3% and 95.9% and for FSx 95.5% and 100% respectively. The diagnostic accuracy of FNA and FSx were 93.5% and 98.9% respectively. Based on a definite histologic diagnosis, the ultrasonographic examination had a sensitivity and a specificity of 77.2% and 78.9%. Conclusion: The results confirm that FNA cytology is a reliable and useful tool in the initial evaluation of a palpable thyroid mass compared to the ultrasonographic examination. Intraoperative FSx is a valuable diagnostic procedure to confirm the cytological diagnosis with undetermined or unsatisfactory cytological diagnosis.

절연파괴시험법을 이용한 3.3[kV] 유도전동기의 절연물 열화특성 분석 (Analysis of Aging Insulation Characteristics of 3.3[kV] Class Induction Motor with AC Breakdown Test)

  • 이주;김현일;김윤현;손영규
    • 조명전기설비학회논문지
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    • 제21권10호
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    • pp.141-149
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    • 2007
  • 본 논문은 유도전동기 고정자권선의 절연물에 대하여 비파괴 및 파괴시험을 실시하여 절연물의 비파괴특성과 내전압강도와의 상호관계를 비교, 평가, 분석함으로써, 향후 전동기의 절연상태 평가시 수명 및 절연진단의 신뢰성을 도모하고자 제안하였다. 본 논문에서는 비파괴시험과 파괴시험과의 상관관계를 평가하기위하여 비파괴시험으로 절연저항시험, 성극지수시험, 유전정접시험, 부분방전시험을 실시하였으며, 파괴시험은 60[kV] AC 내전압를 이용하여 실시하였다. 또한 장기간 사용된 전동기 권선의 절연물에 대한 연구결과로부터 기존 선진국의 진단방법 및 판정기준이 국내에서 제작된 전동기에 대한 절연특성 평가 및 분석에도 타당함을 증명하였으며, 향후 본 논문에서 제시한 자료들은 유사조건의 산업현장에서 운용중인 유도전동기의 수명 및 상태 평가를 위한 기초자료로 유용하게 사용될 수 있으리라 기대된다.

기능성 소화불량 환자에서 설태후박 및 흉늑각 측정의 진단적 가치 (Diagnostic Values of Tongue Coating Thickness and Sterno-costal Angle in Functional Dyspepsia)

  • 손지영;김진성
    • 대한한방내과학회지
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    • 제35권2호
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    • pp.157-174
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    • 2014
  • Objectives : The aims of this study were to evaluate the diagnostic values of tongue coating thickness and sterno-costal angle as the quantitative diagnostic indicators in functional dyspepsia. Methods : We surveyed 60 functional dyspepsia patients recruited by the clinical trial, 'Clinical Trial for Evaluation on Availability of tongue diagnosis system (CTS-1000) : a Pilot study'. The patients were classified into three groups according to Rome III criteria for functional dyspepsia, and categorized into five groups according to Instrument of pattern identification for functional dyspepsia. Nepean dyspepsia index-Korean version (NDI-K) score, tongue coating thickness (percentage of tongue coating by tongue diagnosis system (CTS-1000), and weight of tongue coating by microbalance), sterno-costal angle, duration of illness and body mass index (BMI) were investigated. Results : Among the 5 types by instrument of pattern identification for functional dyspepsia, a significant difference of percentage of tongue coating was found. Percentage of tongue coating and weight of tongue coating showed significant correlation with total NDI-K score. Sterno-costal angle showed strong positive correlation with BMI and also showed significant difference between the non-overweight (BMI<23, n=32) and overweight ($BMI{\geq}23$, n=28) groups. Conclusions : Tongue coating thickness showed its potential as a new quantitative diagnostic indicator of functional dyspepsia. Further studies on the sterno-costal angle are anticipated to evaluate its potential as a new quantitative diagnostic indicator.

초·중학생 대상 웹기반 진단평가관리시스템 사용성 개선을 위한 휴리스틱스 개발 및 검증 (Development and validation of heuristics for usability improvements on web-based diagnostic assessment management system for primary-middle schoolers)

  • 차현진;황윤자
    • 정보교육학회논문지
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    • 제21권6호
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    • pp.675-690
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    • 2017
  • 4차 산업혁명 시대를 맞이하여 증거기반의 교육정책을 위해, 전국단위의 진단평가 데이터를 수집하기 위한 시스템을 구축 활용하고 있다. 본 연구는 이러한 전국 단위 초 중생이 활용하고 있는 진단평가관리시스템의 사용성 개선을 도울 수 있는 휴리스틱스 개발을 목적으로 하였다. 이를 위해 Nielsen의 기본 휴리스틱스를 비롯하여 교육적 목적에 종속적으로 개발된 휴리스틱스에 대한 선행연구를 기반으로 유사시스템인 진단 보정학습시스템의 사용성 문제를 분석함으로써 휴리스틱스 초안을 개발하였다. 이는 델파이 방법을 통해 15명의 전문가에 의해 2회의 타당화 과정을 수행함으로써 수정 보완되었고 최종안이 도출되었다. 본 연구는 교육 맥락에서 사용성 평가도구를 제공함으로써 전국단위의 관계자(교사 등)와 학생들이 활용하는 시스템의 사용성 개선을 위한 기반을 마련하였다는데 의의가 있다.