• Title/Summary/Keyword: Diagnosis of COVID-19

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False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases

  • Dasheng Li;Dawei Wang;Jianping Dong;Nana Wang;He Huang;Haiwang Xu;Chen Xia
    • Korean Journal of Radiology
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    • v.21 no.4
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    • pp.505-508
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    • 2020
  • The epidemic of 2019 novel coronavirus, later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still gradually spreading worldwide. The nucleic acid test or genetic sequencing serves as the gold standard method for confirmation of infection, yet several recent studies have reported false-negative results of real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). Here, we report two representative false-negative cases and discuss the supplementary role of clinical data with rRT-PCR, including laboratory examination results and computed tomography features. Coinfection with SARS-COV-2 and other viruses has been discussed as well.

Analysis of the Status of Artificial Medical Intelligence Technology Based on Big Data

  • KIM, Kyung-A;CHUNG, Myung-Ae
    • Korean Journal of Artificial Intelligence
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    • v.10 no.2
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    • pp.13-18
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    • 2022
  • The role of artificial medical intelligence through medical big data has been focused on data-based medical device business and medical service technology development in the field of diagnostic examination of the patient's current condition, clinical decision support, and patient monitoring and management. Recently, with the 4th Industrial Revolution, the medical field changed the medical treatment paradigm from the method of treatment based on the knowledge and experience of doctors in the past to the form of receiving the help of high-precision medical intelligence based on medical data. In addition, due to the spread of non-face-to-face treatment due to the COVID-19 pandemic, it is expected that the era of telemedicine, in which patients will be treated by doctors at home rather than hospitals, will soon come. It can be said that artificial medical intelligence plays a big role at the center of this paradigm shift in prevention-centered treatment rather than treatment. Based on big data, this paper analyzes the current status of artificial intelligence technology for chronic disease patients, market trends, and domestic and foreign company trends to predict the expected effect and future development direction of artificial intelligence technology for chronic disease patients. In addition, it is intended to present the necessity of developing digital therapeutics that can provide various medical services to chronically ill patients and serve as medical support to clinicians.

Investigation on the situation of violence against medical staffs occurring in Korean medicine clinics (한방 의료기관 내 의료인 대상 폭력 피해에 대한 실태 조사)

  • Kyungsook Han;Donghyun Nam
    • Journal of Society of Preventive Korean Medicine
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    • v.27 no.3
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    • pp.69-81
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    • 2023
  • Objectives : The purpose of this survey is to investigate the current status of violence that occurred in Korean medicine clinics targeting medical staff. Methods : First, questionnaires were developed to investigate the actual situation of violence against medical personnel occurring within Korean medicine clinics. The questions consist of five items on the characteristics of the respondent, ten items on identifying the actual state of violence against Korean medical workers, two items on relevance to COVID-19, two items on related legal issues, and three items on policies. The survey was conducted online from 16 November 2021 to 30 November 2021. Results : Total 519 Korean medical doctors responded to the questionnaire, and 314 (60.50%) responded that they had experienced violence demage while working. While the female staffs experience significantly more violence (𝜒2=18.398, p <0.001) and sexual violence (𝜒2=74.855, p <0.001) than the males, the males tend to be more exposed to physical assault than the female (𝜒2=3.900, p = 0.048). Conclusion : Through this study, we identified the situation of violence against medical staffs in Korean medicine clinics, and concluded that it should be necessary to establish strategies for the prevention and management of violence in a social and institutional way.

Role of biomarkers in antimicrobial stewardship: physicians' perspectives

  • Hyeri Seok;Dae Won Park
    • The Korean journal of internal medicine
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    • v.39 no.3
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    • pp.413-429
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    • 2024
  • Biomarkers are playing an increasingly important role in antimicrobial stewardship. Their applications have included use in algorithms that evaluate suspected bacterial infections or provide guidance on when to start or stop antibiotic therapy, or when therapy should be repeated over a short period (6-12 h). Diseases in which biomarkers are used as complementary tools to determine the initiation of antibiotics include sepsis, lower respiratory tract infection (LRTI), COVID-19, acute heart failure, infectious endocarditis, acute coronary syndrome, and acute pancreatitis. In addition, cut-off values of biomarkers have been used to inform the decision to discontinue antibiotics for diseases such as sepsis, LRTI, and febrile neutropenia. The biomarkers used in antimicrobial stewardship include procalcitonin (PCT), C-reactive protein (CRP), presepsin, and interleukin (IL)-1β/IL-8. The cut-off values vary depending on the disease and study, with a range of 0.25-1.0 ng/mL for PCT and 8-50 mg/L for CRP. Biomarkers can complement clinical diagnosis, but further studies of microbiological biomarkers are needed to ensure appropriate antibiotic selection.

A Brief Review of Research and Development, Market Trends for Ultra-Small and High-Sensitivity Nano Biosensors (초소형 고감도 나노 바이오 센서의 연구개발 및 시장 동향)

  • Hyeong Gi Park;Jun-Won Kook;Kwon-Young Choi;Jae-Hyun Lee
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.36 no.6
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    • pp.556-562
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    • 2023
  • This paper presents the development and market trends of nano biosensors. These biosensors must possess high sensitivity and selectivity to effectively detect diseases. Presently, many research groups are focusing on the field-effect transistor aspect of nano biosensors, which can identify diseases such as Down syndrome, bladder cancer, breast cancer, and numerous other cancers, utilizing graphene and transition metal dichalcogenide materials. In the case of in-vitro diagnostics, the use of nano biosensors has been rapidly growing since the onset of the COVID-19 pandemic. This paper also discusses market trends and the outlook for both national and international enterprises engaged in the nano biosensor field. Nano biosensors are expected to play a beneficial and significant role soon, contributing to the early diagnosis of diseases and subsequently improving patient outcomes.

The Influence of Individual's Health Beliefs on the Intention to Use Mobile Healthcare Apps: Focusing on the Moderating Role of mHealth Literacy (개인의 건강신념이 모바일 헬스케어 앱 이용의도에 미치는 영향: m헬스 리터러시의 조절효과를 중심으로)

  • Jin-Seob Wang;Jaemin Song;Sung-Byung Yang;Sang-Hyeak Yoon
    • Journal of Information Technology Services
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    • v.22 no.1
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    • pp.95-114
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    • 2023
  • Smart healthcare, combining ICT (Information and Communications Technologies) and medical technologies, has been rapidly emerging. Accordingly, its market has also increased as interest in disease prevention, management, and diagnosis grows due to the COVID-19 pandemic. In particular, using mobile devices to support medical activities, mobile healthcare has been attracting attention as a leading service in the smart healthcare market. However, the intention to use mobile healthcare apps may vary depending on individual beliefs and attitudes. Many studies on the intention to use mobile healthcare apps have used the TAM (Technology Acceptance Model), but there is a lack of studies that have been verified from the perspective of users' health beliefs. This study aims to identify the factors that affect the intention to use mobile healthcare apps based on the HBM (Health Belief Model). Furthermore, it investigates how this influencing mechanism fluctuates based on the user's mHealth literacy, the ability to find and understand health information through mobile. This study contributes to the empirical examination of the intention to use mobile healthcare apps through the HBM. It also offers insights for app providers and public health officials to increase the use of mobile healthcare apps.

Proposed ICT-based New Normal Smart Care System Model to Close Health Gap for Older the Elderly

  • YOO, Chae-Hyun;SHIN, Seung-Jung
    • International journal of advanced smart convergence
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    • v.10 no.2
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    • pp.37-44
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    • 2021
  • At the time of entering the super-aged society, the health problem of the elderly is becoming more prominent due to the rapid digital era caused by COVID-19, but the gap between welfare budgets and welfare benefits according to regional characteristics is still not narrowed and there is a significant difference in emergency medical access. In response, this study proposes an ICT-based New Normal Smart Care System (NNSCS) to bridge the gap I n health and medical problems. This is an integrated system model that links the elderly themselves to health care, self-diagnosis, disease prediction and prevention, and emergency medical services. The purpose is to apply location-based technology and motion recognition technology under smartphones and smartwatches (wearable) environments to detect health care and risks, predict and diagnose diseases using health and medical big data, and minimize treatment latency. Through the New Normal Smart Care System (NNSCS), which links health care, prevention, and rapid emergency treatment with easy and simple access to health care for the elderly, it aims to minimize health gaps and solve health problems for the elderly.

Trends in Diagnostic Technology for Respiratory Infectious Disease (호흡기 감염병 진단 기술 동향)

  • J.W. Park;H.-S. Seo;C. Huh;S.J. Park
    • Electronics and Telecommunications Trends
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    • v.39 no.4
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    • pp.54-62
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    • 2024
  • The emergence and resurgence of novel respiratory infectious diseases since the turn of the millennium, including SARS, H1N1 flu, MERS, and COVID-19, have posed a significant global health threat. Efforts to combat these threats have involved various approaches, however, continued research and development are crucial to prepare for the possibility of emerging viruses and viral variants. Direct detection methods for viral pathogens include molecular diagnostic techniques and immunodiagnostic methods, while indirect diagnostic methods involve detecting changes in the condition of infected patients through imaging diagnostics, gas analysis, and biosignal measurement. Molecular diagnostic techniques, utilizing advanced technologies such as gene editing, are being developed to enable faster detection than traditional PCR methods, and research is underway to improve the efficiency of diagnostic devices. Diagnostic technologies for infectious diseases continue to evolve, and several key trends are expected to emerge in the future. Automation will facilitate widespread adoption of rapid and accurate diagnostics, portable diagnostic devices will enable immediate on-site diagnosis by healthcare professionals, and advancements in AI-based deep learning diagnostic models will enhance diagnostic accuracy.

Analysis on Awareness of Make-up and Image-Making of the Health Teachers in Gwangju Metropolitan City by In-depth Interview (심층면접법을 이용한 광주지역 보건 교사의 이미지 메이킹에 관한 인식 분석)

  • Seohyun, Oh
    • Fashion & Textile Research Journal
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    • v.24 no.6
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    • pp.782-788
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    • 2022
  • Our research participants were composed of health teachers exhausted by the COVID-19 pandemic. This study analyzed the attitudes towards image-making through utilizing the job training at Gwangju Metropolitan Office of Education on August 2022, where our study was able to obtain and analyze 30 elementary, middle, and high school health teachers who participated. Image making is defined as playing a role in increasing self-esteem through outward appearances such as facial expressions and posture, personal color, makeup, tone, hairstyling, and fashion and impacting individuals inwardly to increase self-confidence. Therefore, there is a positive impact in providing an image-making program that considers the occupational characteristics of a health teacher. It had the effect of stress relief and aided in building a healthier self-image among the participants. The results our study showed the following results. First, all participants had various concerns regarding their appearance and deemed that image-making was necessary, yet they needed to be more informed regarding the specific methods of doing so. Secondly, participants were mainly focused on purchasing makeup products for image making. Although participants showed interest in a personal color diagnosis, there needed to be more support in approaching the subject as the diagnosis was necessary from an expert. Third, participants stated that image-making should occur for their middle-aged selves when experienced in the field. Participants believed that they would be more concerned with how others viewed them after gaining expertise. Hence, this study found that the occupational characteristics of health teachers greatly benefitted from image-making programs oriented to their careers and would also show an increase in job satisfaction.

Development and Application of Assessment Items for the Diagnosis of Difficulties in Learning Elementary Mathematics (초등학교 수학 학습 어려움 진단을 위한 평가 문항 개발 및 적용 연구)

  • Kim, Hee-jeong;Cho, Hyungmi;Ko, Eun-Sung;Lee, Donghwan;Cho, Jinwoo;Choi, Jisun;Han, Chaereen;Hwang, Jihyun
    • Journal of the Korean School Mathematics Society
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    • v.25 no.3
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    • pp.261-278
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    • 2022
  • The purpose of this study is to develop an assessment to diagnose difficulties in learning mathematics and misconstructions that elementary students have. With thorough theoretical background and analysis of mathematics curriculum documents, we established learning trajectories for the following content areas in grades 3 to 6: number and operation, regularity, data and chance, geometry, and measurement. Then, the research team created the assessment items targeting a specific stage in the learning trajectories and including item options to identify possible misconceptions. Based on the unified validity theory, we reported the detailed procedure of the assessment development and the evidence for the content, substance, and structural validity of the assessment. We collected the data of 675 elementary students. Rasch measurement modeling was applied, and Cronbach's alpha was estimated. We considered how to report students' assessment results to teachers appropriately and immediately, which suggested important implications for supporting teaching and learning mathematics in elementary schools. We also suggested how to use the assessment developed in this study in online and distance learning environments due to the COVID-19 pandemic.