• Archives of Pharmacal Research
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• 제27권7호
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• pp.734-737
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• 2004

5,8-Epidioxycholest-6-en-3-ol (1), cholesterol (2), glycerol 1-palmitate (3) and glycerol 1,3-dioleate-2-stearate (4) were isolated from the methanol extract of the sea urchin Diadema setosum, which was collected from the Halong sea, Vietnam. Chemical structures were established based on extensive 1D, 2D-NMR, FAB-MS, EI-MS spectroscopic data and GC-MS analysis. The NMR spectral data of compound 1 were reassigned by using HMQC and HMBC. Compound 1 was found to have strong cytotoxic effect against various cancer cell lines, such as KB ($IC_{50}$, 2.0 $\mu\textrm{g}$/mL), FL($IC_{50}$, 3.93 $\mu\textrm{g}$/mL), and Hep-2 ($IC_{50}$, 2.4 $\mu\textrm{g}$/mL) by in vitro assay.

• Animal Systematics, Evolution and Diversity
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• 제16권2호
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• pp.219-226
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• 2000

제주도 모슬포 해안의 수심 약 20 m 지점에서 채집된 성게류를 동정 분류한 결과, 왕관성게목의 가시왕관성게 (Diadema setosum)와 성게목의 주발성게 (Toxopneustes pileolus)가 한국 미기록종으로 밝혀져 보고한다. 왕관성게목 (Diadematoida)은 우리나라에서 처음으로 보고된다. 이로써 제주도 해역에 분포하는 성게류는 12종이 된다.