• 제목/요약/키워드: DiD

검색결과 627건 처리시간 0.027초

다중 ON-OFF 소스에 대한 ISDN AO/DI 기능의 성능분석 (Performance Analysis of ISDN AO/DI Scheme with Multiople ON-OFF sources)

    • 한국통신학회논문지
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    • 제24권10B호
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    • pp.1861-1866
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    • 1999
  • ISDN은 사용자에게 mB+1D의 channel을 제공한다. AO/DI기능은 D-channel을 통하여 저속의 지속적인 연결을 제공하며 고속의 통신이 필요한 경우에는 B-channel을 통하여 고속의 대역폭을 제공한다. 본 논문에서는 ISDN 환경에서의 다중 ON-OFF 소스에 대한 AO/DI기능의 성능분석을 수행한다. 다중 ON-OFF 소스가 하나의 mB+1D ISDN 링크를 통하여 연결되어 있는 상황을 가정한다. AO/DI 기능이 구현안된 경우 요구되는 대역폭은 모든 소스의 피크 대역폭의 합으로 주어지나 AO/DI 기능이 구현된 경우에는 실제로 사용되어지는 대역폭에 근접하게 대역폭이 할당된다.

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The Reaction of Superoxide with Carbohydrate Sulphonates

  • Shin, Young-Sook;Nam Shin, Jeong E.
    • Bulletin of the Korean Chemical Society
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    • 제14권2호
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    • pp.188-191
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    • 1993
  • The reaction between methyl 2,3-di-O-benzyl-4,6-di-O-mesyl-${\alpha}$-D-glucopyranoside (1b) and potassium superoxide resulted in hydrolysis, and gave methyl 2,3-di-O-benzyl-${\alpha}$-D-glucopyranoside (1) as a sole product. When the reaction was performed with a vicinal dimesylate, methyl 4,6-O-benzylidene-2,3-di-O-mesyl-${\alpha}$-D-altropyranoside (4b), again the hydrolysis product, methyl 4,6-O-benzylidene-${\alpha}$-D-altropyranoside (4) was obtained. However, the reaction of potassium superoxide with another vicinal dimesylate, methyl 4,6-O-benzylidene-2,3-di-O-mesyl-${\alpha}$-D-glucopyranoside (3b), nucleophilic displacement took place to afford methyl 4,6-O-benzylidene-${\alpha}$-D-altropyranoside (4). Apparently different results from two trans vicinal dimesylates, 3b and 4b are explained by the transient formation of epoxides, methyl 2,3-anhydro-4,6-O-benzylidene-${\alpha}$-D-allopyranoside (8) and methyl 2,3-anhydro-4,6-O-benzylidene-${\alpha}$-D-mannopyranoside (9) by $KO_2$. The reaction between the allo epoxide 8 and $KO_2$ gave altro 4. The manno epoxide 9 also afforded altro 4 as the major product. Facile epoxide formation by the reaction of a vicinal dimesylate and superoxide was also observed with 3-O-benzyl-1,2-O-isopropylidene-5,6-di-O-mesyl-${\alpha}$-D-glucofuranose: 5,6-anhydro-3-O-benzyl-1,2-O-isopropylidene-${\beta}$-L-idofuranose was obtained.

Near-infrared (NIR) 영상기법을 이용한 생체 내 수지상세포의 이동 (In vivo Dendritic Cell Migration Tracking Using Near-infrared (NIR) Imaging)

  • 이준호;정남철;이은계;임대석
    • KSBB Journal
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    • 제27권5호
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    • pp.295-300
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    • 2012
  • Matured dendritic cells (DCs) begin migration with their release from the bone marrow (BM) into the blood and subsequent traffic into peripheral lymphoid and non-lymphoid tissues. Throughout this long movement, migrating DCs must apply specialized skills to reach their target destination. Non-invasive in vivo cell-tracking techniques are necessary to advance immune cell-based therapies. In this study, we used a DiD cell-tracking solution for in vivo dendritic cell tracking in naive mice. We tracked DiD (non-invasive fluorescence dye)-labeled mature dendritic cells using the Near Infrared (NIR) imaging system in normal mice. We examined the immunophenotype of DiD-labeled cells compared with non-labelled mature DCs, and obtained time-serial images of NIR-DC trafficking after mouse footpad injection. In conclusion, we confirmed that DiD-labeled DCs migrated into the popliteal lymph node 24 h after the footpad injection. Here, these data suggested that the cell tracking system with the stable fluorescence dye DiD was useful as a cell tracking tool to advance dendritic cell-based immunotherapy.

Isolation and Identification of Chondroitin Sulfates from the Mud Snail

  • Lee, Kyung-Bok;Kim, Jong-Sig;Kwak, Sang-Tae;Sim, Won-Bo;Kwak, Jong-Hwan;Kim, Yeong-Shik
    • Archives of Pharmacal Research
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    • 제21권5호
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    • pp.555-558
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    • 1998
  • chondroitin sulfates were isolated from the mud snail. For the quantitative analysis of enzymatic digestion products of isolated chondroitin sulfates, strong anion exchange-high performance liquid chromatography (SAX-HPLC) was performed. by the action of chondroitinase ABC, three unsaturated disaccharides$ 2-acetamide-2-deoxy-3-O-({\beta}-D-gluco-4-enepyranosyluronic acid)-D-galactose $$({\Delta}Di-OS), $2-acetamide-2-deoxy-3-O-({\beta}-D-gluco-4-enepyranosyluronic acid)-6-O-sulfo-D-galactose ({\Delta}Di-6S) and 2-acetamide-2-deoxy-3-O-({\beta}-D-gluco-4-enepyranosyluronic acid)-4-O-sulfo-D-galactose ({\Delta}Di-4S)$ were produced from the mud snail chondroitin sulfates. The analysis showed that relative proportion of ${\Delta}Di-OS/{\Delta}Di-6S/{\Delta}Di-4S$ was 58.7/3.1/38.2. The immunomodulating activity of chondroitin sulfate was examined by cell proliferation assay and these results suggest that it might be a immunosuppressant.

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주체와 타자의 존재방식과 재현 양상 -이탈리아 이주문학을 중심으로- (Il riassunto Aspetto di ricomparsa e maniera d'essere di gli altri e il soggetto -sulla letteratura italiana della migrazione-)

  • 김희정
    • 이탈리아어문학
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    • 제32호
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    • pp.23-48
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    • 2011
  • Se siamo d'accordo la definizione di Deleuze e Guattari che la letteratura minore è la letteratura che costruisce una minoranza dentro la lingua maggiore, le scritture italofoniche sono la traduzione in pratica di un concetto della letteratura minore che fornisce modelli sostitutivi di espressione. Questa minoranza di bilingue, o più precisamente, multilingue autori e pratiche, acquisisce uno spazio dentro della cultura e la lingua italiana, che di conseguenza sono entrambi deterritorializzati. Lo stanziamento di italiano come lingua in cui sono scritti i testi italofonici richiede una pratica influenza linguistica e culturale. Questa ibridazione linguistica e letteraria riverbera la pluralità sociale presente nella moderna Italia, dove oltre un milione di immigrati provenienti da tutto il mondo vivono oggi. Questo collegamento tra il letterario e il sociale si diffonde il senso di deterritorializzazione linguistica per definire personificazioni di 'otherness', sia per i corpi degli immigrati stessi sia per la politica. I testi italofonici rapresentano contemporaneamente l'individuo e il collettivo, cioè, l'esperienza individuale e la vita delle comunità di immigrati.

두충으로부터 분리한 Iignan glycoside 의 ACE 활성 억제 (ACE Inhibitory Lignan Glycosides Isolated from Eucommia ulmoides Oliver)

  • 주옥수;남상해
    • 생명과학회지
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    • 제19권6호
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    • pp.698-704
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    • 2009
  • 두충 (Eucommia ulmoides Oliver)으로부터 항고혈압 활성을 가진 유효물질을 분리하였으며, 두충의 잎, 껍질 및 줄기를 건조한 것과, 건조한 후 붉은 것에 대하여 ACE (angiotensin converting enzyme) 저해활성을 실험하였다. 두충으로부터 분리 한 유효물질은 pinoresinol-4,4'-di-O-${\beta}$-D-glucoside (PG)와 dehydrodiconiferyl alcohol 4,${\gamma}$'-di-O-${\beta}$-D-glucoside (DAG)였으며, 이들은 각각 껍질과 잎에 많이 함유되 어 있었다. 즉 pinoresinol-4,4'-di-O-${\beta}$-D-glucoside (PG)는 자연 건조한 껍질에 135.12 mg%, 붉은 껍질에 163.94 mg%로 가장 많이 함유되어 있었으며, dehydrodiconiferyl alcohol 4,${\gamma}$'-di-O-${\beta}$-D-glucoside (DAG)는 자연 건조한 잎에 117.43 mg%, 붉은 잎에 133.93 mg%로 비교적 많이 함유되어 있었다. ACE 억제활성은 볶은 잎, 말린 껍질 및 볶은 껍질을 10 mg/ml씩 처리하였을 때, 각각 77.49, 75.52 및 75.36%의 억제효과를 나타내었으며, 두충으로부터 분리한 화합물인 pinoresinol-4,4'-di-O-${\beta}$ -D-glucoside (PG)와 dehydrodiconiferyl alcohol 4,${\gamma}$'-di-O-${\beta}$-D-glucoside (DAC)를 1${\sim}$10 mg/ml 처리하였을 때에 는 67.1${\sim}$85.25% 의 억제활성을 나타내었으며, $IC_{50}$값은 각각 0.6${\pm}$0.2, 0.5${\pm}$0.2 mg/ml 였다. 이것은 PG와 DAG가 두충에서 분리한 천연물임을 감안하면 매우 높은 활성을 가지고 있다고 할 수 있다.

정맥용 면역글로불린 투여로 호전된 항-$Di^a$ 항체에 의한 신생아 용혈성 질환 1예 (A Case of Hemolytic Disease of a Newborn by an Anti-$Di^a$ Antibody Treated with Intravenous Immunoglobulin)

  • 이창언;박수진;김원덕
    • Journal of Yeungnam Medical Science
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    • 제30권1호
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    • pp.21-24
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    • 2013
  • Hemolytic disease in a newborn that causes early jaundice is common. It is often due to the Rh (D) and ABO incompatibility, but rarely due to unexpected antibodies. Among these unexpected antibodies, the anti-$Di^a$Dia antibody rarely occurs. The anti-$Di^a$ antibody was observed in the serum and red-cell eluate of an infant, and in the serum of his mother. The frequency of the appearance of the $Di^a$ antigen in the Korean population is estimated to be 6.4-14.5%. This paper reports a case of hemolytic disease in a newborn associated with the anti-$Di^a$ antibody. A full-term male infant was transferred to the authors' hospital due to hyperbilirubinemia the day after his birth. The laboratory data indicated a hemoglobin value of 11.6 g/dL, a reticulocyte count of 10.6%, a total bilirubin count of 14.4 mg/dL, a direct bilirubin count of 0.6 mg/dL, and a positive result in the direct Coombs' test. Due to the identification of an irregular antibody from the maternal serum, an anti-$Di^a$ antibody was detected, which was also found in the eluate made from the infant's blood. The infant had been treated with phototherapy and intravenous immunoglobulin since the second day after his birth and was discharged due to an improved condition without exchange transfusion. Therefore, in cases of iso-immune hemolytic disease in a newborn within 24 hours from birth who had a negative result in an antibody screening test, the conduct of an anti-$Di^a$ antibody identification test is recommended due to the suspicion of an anti-$Di^a$ antigen, followed by early administration of intravenous immunoglobulin.

Effects of four dim vs high intensity red color light regimens on growth performance and welfare of broilers

  • Senaratna, D.;Samarakone, T.S.;Gunawardena, W.W.D.A.
    • Asian-Australasian Journal of Animal Sciences
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    • 제31권1호
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    • pp.149-156
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    • 2018
  • Objective: Broilers show clear preference towards red color light (RL). However setting of an optimum light intensity is difficult since dim intensities that favor growth reduce welfare. This experiment was conducted to test the most effective RL intensity regimen (Dim [5 lux; DI] vs high [320 lux; HI]) in combination applied at different growth stages that favors for both performance and welfare. Methods: Complete randomize design was adopted with 6 replicates. Treatments were; T1 = early DI (8-21 d)+latter HI (22-35 d); T2 = early DI (8-28 d)+latter HI (29-35 d), T3 = early HI (8-21 d)+latter DI (22-35 d), T4 = early HI (8-28 d)+latter DI (29-35 d) and T5 = control (white light; WT) (8-35 d) at medium intensity (20 lux). Body weight (BW), weight gain (WG), water/feed intake and ratio, feed conversion ratios (FCR) were assessed. Common behaviours (15) were recorded by scan sampling method. Lameness, foot pad dermatitis, breast blisters, hock burning damage were assessed as welfare parameters. Fear reactions were tested using Tonic Immobility Test. Ocular and carcass evaluations were done. Meat and tibiae were analyzed for fat and bone ash respectively. Results: On 35 d, the highest BW ($2,155.72{\pm}176g$), WG ($1,967.78{\pm}174g$) were recorded by T2 compared to WT ($BW_{WT}=1,878.22{\pm}155$, $WG_{WT}=1,691.83{\pm}160$). But, application of RL, either DI, or HI during early/latter stage had no significant effect on FCR. Under HI, birds showed much higher active behaviours. DI encourages eating. Though LI changed from DI to HI, same trend could be seen even under HI. The highest leg strength ($218.5{\pm}120s$) was recorded by T2. The lowest leg strength ($64.58{\pm}33s$) and the highest ocular weight ($2.48{\pm}1g$) were recorded by T1. Significantly (p<0.05) the highest skin weight ($162.17{\pm}6g$) but the lowest fat% in meat ($13.03%{\pm}5%$) was recorded by T2. Conclusion: Early exposure to DI-RL up to 28 days followed by exposure to HI-RL is the most favorable lighting regimen for optimizing production, better welfare of broilers and improving health benefits of meat.

ASYMPTOTIC FOR THE NUMBER OF STAR OPERATIONS ON ONE-DIMENSIONAL NOETHERIAN DOMAINS

  • Spirito, Dario
    • 대한수학회지
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    • 제58권5호
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    • pp.1239-1260
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    • 2021
  • We study the set of star operations on local Noetherian domains D of dimension 1 such that the conductor (D : T) (where T is the integral closure of D) is equal to the maximal ideal of D. We reduce this problem to the study of a class of closure operations (more precisely, multiplicative operations) in a finite extension k ⊆ B, where k is a field, and then we study how the cardinality of this set of closures vary as the size of k varies while the structure of B remains fixed.