• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.8 no.2
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• pp.256-265
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• 1997

Objectives：The purpose of this study was to investigate the characteristics and differences of brain function in pervasive developmental disorder and developmental language disorder. Method：The subjects were composed of 14 cases of pervasive developmental disorder and 13 cases developmental language disorder. They were investigated by technitium-99m-EDC SPECT. All SPECT were visually assessed by two nuclear medicine specialists, and then quantified by region of interest including temporal, parietal cortex, thalamus, basal ganglia and cerebellum. Result：In both groups, cerebral blood flow was decreased in the temporal, parietal cortex, basal ganglia, thalamus, cerebellum by visual assessment. There was no significant difference between the 2 groups by quantitative and qualitative assessment. Conclusion：These results suggest that pervasive developmental disorder and developmental language disorder are caused by defects in the interneural connection and that both disorders are spectrum disorders.