• 한국발생생물학회지:발생과생식
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• 제21권3호
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• pp.297-305
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• 2017

An experiment was conducted to investigate the annual reproductive cycle of a Korean endemic species, Acheilognathus majusculus, from Jeokseong-myeon located in Seomjin River. The reproductive cycle is examined histologically regarding water temperature and day length of the habitat, the gonadosomatic index (GSI), the female ovipositor length index (OLI), monthly variation in egg diameter distribution, and developmental characteristics of female and male gonads. The maximum GSI was found in $19.21{\pm}2.32$ and $6.90{\pm}0.53$ for female and male respectively when water temperature ($14^{\circ}C$) and day length (11.1hr) began to rise. On the other hand, the minimum level was reached during August ($1.87{\pm}0.67$ for female and $0.88{\pm}0.50$ for male). No samples represent with measurable ovipositor between September and November, while the longest ovipositor length index was in April ($79.68{\pm}4.69%$). We compared and calculated the stages of testis and ovary development process in order to determine the germ cell development characteristics and the reproductive cycle. According to the result, we classified the female Acheilognathus majusculus reproductive cycle into four stages: Ripe (April) and spawning phase (May to June), degenerative phase (July), growing phase (August to December), and mature phase (January to March). The annual reproductive cycle of male Acheilognathus majusculus was categorized into five stages viz. Ripe and spawning phase (May to June), degenerative phase (July to August), resting phase (September to November), growing phase (December to February), and mature phase (March to April).

• 환경영향평가
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• 제15권6호
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• pp.385-394
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• 2006

Land resources should be managed not only for human utilizations but also for environmental preservation. Based on that, environmental capacity should be estimated in both environmental and developmental ways. This study was performed for developing an estimation model for relative environmental capacity, considering both Development Tolerance Index(DTI), which shows environmental and ecological conservation value and is based on national environmental assessment indicators of the Korea Ministry of Environment, and Development Attractiveness Index(DAI), which shows topographical characteristics and geographical accessibility. The relative environmental capacity in this study can be helpful to coping with the conflict in planning and managing the use of land resources. The relative environmental capacity in this study, however, did not include either environmental or ecological sensitivity of land resources. This limitation should be solved through further research.

• 한국수정란이식학회지
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• 제9권3호
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• pp.269-277
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• 1994

The objective of this study was to develop an effective in vitro production system capable of obtaining more porcine embryos from immature oocytes These experiments were conducted to examine the effect of sperm factor on the IVF and IVD, and the effect of coculture with somatic cells on the IVD of embryos. Although the concentration of epididymal sperm for IVF did not affect on cleavage rate, but 5 x 105 sperm/mi showed the highest cleavage rate(48.7%) and the developmental potential of IVF oocytes from this concentration was also greatly higher (P$^{\circ}C$-stored sperm for l2hrs and the cleavage rate from fresh sperm was significantly higher (P<0.05) than that from frozen sperm, but the developmental potential after IVF was slightly high from the frozen sperm. The cleavage rate of IVF oocytes cocultured with oviductal epithelial cells and cumulus cells was 76.3% and 72.9%, respectively. There was no difference between two coculture systems but this rate was significantly higher(P<0.05) than that of medium alone(42.0%).

• 한국발생생물학회지:발생과생식
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• 제15권3호
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• pp.257-263
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• 2011

Gonadal development and reproductive cycle of Aplysia kurodai inhabiting the coastal waters of Jeju Island, Korea were investigated based on monthly changes of gonadosomatic index, gametogenesis, and developmental phases of ovotestis. A. kurodai was simultaneous hermaphrodite; the ovotestis generally embedded in the posterior dorsal surface of the brownish digestive gland. The ovotestis is composed of a large number of follicles, and both oocytes and sperm are produced in the same follicles. In the sampling periods, the adult A. kurodai population have characteristic of seasonal pattern present during only 10 months. The reproductive cycle can be grouped into the following successive stages in the ovary: inactive (December to February), active (December to April), mature and spawning (April to September). The gonadal development of A. kurodai coincided with rising temperature, and spawning occurred from April to September, when the temperature was high. The histological observations of the ovotestis suggested that this species have a single spawning season that extend over six months.

• International Journal of Contents
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• 제15권2호
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• pp.44-52
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• 2019

This paper uses Delphi Method and statistics provided by the State Administration of Market Regulation of China, attempts to develop the scale index of language service industry in China. Coupled with practical investigation and theoretical framework of SCP paradigm, a deep analysis on market behavior, market structure, and market performance of the industry have been explored. First, the study indicates that the scale index of Chinese language services industry has experienced an upward trend from 10.481million RMB in 2008 to 351.403 million RMB in 2017. Second, majority of language services enterprises are situated in Chinese coastal provinces and there are variations in demand for language services. Third, the standardization of language services are minimal while most of the talents involve a single discipline background. Fourth, most enterprises utilize language tools while there is lack of technological innovation for utilization of language resources and enhancement of service quality. The author mainly suggests four strategies which include: cultivating multilingual services, strengthening the development of industrial informatization and technical innovation, and optimizing the industrial talents structure while also adjusting for industrial distribution and regional coordination, which propose the meaningful implications for the development of language service industry in China.

• 한국발생생물학회지:발생과생식
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• 제23권4호
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• pp.323-331
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• 2019

In this study, an experiment was conducted to investigate the annual reproductive cycle of a Korean flat bittering, Acheilognathus rhombeus, from Ogok-myeon located in Seomjin River. The reproductive cycle was examined histologically regarding water temperature and day length of the habitat, the gonadosomatic index (GSI), and developmental characteristics of female and male gonads. The maximum GSI was found to be 3.50±0.53 and 1.36±0.14 for females and males, respectively, when the water temperature and day light was 16.9℃ and 11.3 hours, respectively in October 2018. On the other hand, the minimum GSI was found to be 0.16±0.09 and 0.69±0.15 for males and females in December 2018 and February 2019, respectively. The ovipositor of females appeared from August to November 2018. We compared and calculated the stages of germ cell developmental characteristics in the testis and ovaries to determine the reproductive cycle. According to the result, we classified the female A. rhombeus reproductive cycle into four phases, which are ripe and spawning phase (October), degenerative phase (November to December), growing phase (January to March) and mature phase (April to September). The annual reproductive cycle of male A. rhombeus was categorized into four phases: mature phase (June to October), degenerative phase (November to March), resting phase (April) and growing phase (May). The Korean flat bittering is an autumn-spawner as the main spawning season in October. In male, testicular spermatogonia appeared all year-round, and the ripe and releasing phase, which is characteristics of the spawning season in other fish, did not appear.

• Toxicological Research
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• 제23권4호
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• pp.391-403
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• 2007

The study was conducted to assess the repeated dose and reproduction and developmental toxicities of acetanilide, an intermediate for drug production, as a part of OECD Screening Information Data Set (SIDS) program. The test agent was administered by gavage at dose levels of 0, 22, 67, 200 and 600 mg/kg to Sprague-Dawley rats (12/group/sex) during pre-mating and mating period for males(up to 30 days) and females and pregnancy and early lactation period for females (up to 39-50 days). At 22 mg/kg, decreases in HGB, HCT (males) and MCHC (females), hyperplasia of spleen red pulp, hyperplasia of femur bone marrow (both sexes) were observed. At 67 mg/kg, salivation (males), reduced food consumption (both sexes), decreases in RBC, HGB, HCT and MCHC (males), increases in MCV (males) and spleen weight (males), hyperplasia of spleen red pulp and femur bone marrow (both sexes) were observed. At 200 mg/kg, decreases in locomotor activity and salivation (both sexes), reduced food consumption (both sexes), decreases in RBC, HGB, HCT and increases in MCV, MCH, BUN, T-BIL (males), enlargement of spleen (both sexes), increased weight of spleen (males), hyperplasia of spleen red pulp and femur bone marrow and extramedullary hematopoiesis of liver (both sexes), atrophy of thymus and corpus luteum hyperplasia of ovary (females) were observed. At 600 mg/kg, decreases in locomotor activity, cyanosis (both sexes), reddish tear, and salivation (males), mortality (4 out of 12 females), decreased body weight (females), reduced food consumption (both sexes), decreases in RBC, HGB, HCT and MCHC and increases in WBC, MCV, MCH, reticulocyte, neutrophil, lymphocyte, monocyte, AST, ALT, BUN, T-BIL, ALB, Ca and A/G ratio (males), enlargement of spleen, increased weights of spleen (both sexes), liver (males), kidney and ovary, decreased weights of thymus (females), hyperplasia of spleen red pulp, hyperplasia of femur bone marrow and extramedullary hematopoiesis of liver (both sexes), and atrophy of thymus and corpus luteum hyperplasia of ovary (females) were observed. Regarding the reproduction and development toxicities, there were no treatment-related changes in precoital time, mating index, fertility index and pregnancy index at all doses tested. At 22 and 67 mg/kg, there were no adverse effects on all the parameters observed. At 200 mg/ kg, decreased body weight of pups (day 4 p.p.) were observed. At 600 mg/kg, decreased body weight of pups (day 0 and 4 p.p.) and viability index (day 4 p.p.), increased incidence of newborns dead or with abnormal clinical signs were observed. The results suggest that the NOAELs for general toxicity are < 22 mg/kg, LOAELs are 22 mg/kg and the NOAELs for reproductive toxicity are 67 mg/kg.

• 대한간호학회지
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• 제52권4호
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• pp.407-420
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• 2022

Purpose: This structural model study was constructed and verified a hypothetical model to examine the effects of parenting stress, social resources, family resources, and positive coping on resilience among mothers of children with developmental disabilities. Methods: Data were collected using self-report structured questionnaires, from October 19 to October 30, 2018, with 214 mothers caring for children with developmental disabilities under the age of 20 years. Results: In the fitness test results of the hypothesis model, with the fit index 𝛘² (p) = 69.27 (< .001), and the normed fit indices (𝛘² = 1.87, GFI = .94, CFI = .97, NFI = .93, and TLI = .95, RMSEA = .06, SRMR = .06), this study satisfies the good fitness in standards. There are seven statistically significant paths among the 10 paths set in the hypothetical model. The explanatory power of parenting stress and social resources, which affects the family resources was 41.4%, the explanatory power of parenting stress, social resources, and family resources affecting the positive coping was 58.9%, and the explanatory power of parenting stress, social resources, family resources, and positive coping affecting resilience was 55.5%. Conclusion: Positive coping, family resources, and social resources of mothers of children with developmental disabilities directly affect their resilience, and parenting stress indirectly affects it. Therefore, to improve the resilience of mothers of children with developmental disabilities, it is necessary to develop a systematic nursing intervention that considers parenting stress, social resources, family resources, and positive coping.

• 대한물리의학회지
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• 제11권2호
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• pp.103-114
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• 2016

PURPOSE: The purpose of this study was first to develop a Korean version of pediatric functional muscle testing for children with a motor developmental disorder who have a communication problem and who are aged below five years, and also to verify the content validity. METHODS: First, the preliminary study was conducted to verify the reliability of pediatric functional muscle testing, developed by Venita in Korea. Based on the results of the study, the primary evaluation items were selected and modified. Second, the first test of content validity was conducted through a panel discussion, and a second investigation of content validity was carried out by utilizing the Item Content Validity Index (I-CVI). In this study, we selected only 0.78 or more items from I-CVI. RESULTS: Based on the results of the preliminary study, 19 primary evaluation items were selected. Based on the results of the first and second content validity tests, 15 tertiary evaluation items for the Korean version of pediatric functional muscle testing were determined. CONCLUSION: This study developed a new Korean version of pediatric functional muscle testing and suggested that it will be a useful tool to measure muscle strength for Korean children with a motor developmental disorder and a communication problem, aged below five years.

• 한국발생생물학회:학술대회논문집
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• 한국발생생물학회 2001년도 후기 제12차 학술대회 논문집
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• pp.42-44
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• 2001

연중 밀어 (Rhinogobiw brumeu)의 생식소 성숙을 조사하였다. 난소 및 정소의 성숙은 체장 60 mm 이상의 개체에서 뚜렷하였다. 난소는 원추형이며 정소는 쐐기모양으로 복강의 등쪽에 위치한다. 연중 성성숙지수 (gonadosomatic index)의 변화는 암컷 0.19 - 14.28 수컷 0.15-13.34로 산란시기는 5월 하순부터 6월 초순의 하계번식 어류로 사료된다. 성숙기에서 산란기에 이르는 동안 난소내 난자의 성숙정도는 불균질하며 전체 밀어 군집내에서 7월 하순까지도 성성숙지수 (GSI)가 비교적 높게 유지되는 것으로 보아 1차 산란 이후에도 소규모의 산란이 하계에 걸쳐 진행되는 것으로 사료된다. 생식소의 발달은 동계에 시작되어 난소내 난자는 춘계와 하계에 걸쳐 성장이 일어나 지름 0.5 mm의 성숙난자를 형성한다. 이 시기의 정소는 성숙한 정자가 세정관내를 가득 채우고 있다. 정자의 길이는 45 um 이며 두부의 직경은 5 um이며 미토콘드리아를 갖는 중편이 두부 기저부에 함입된 형태이며 첨체를 갖지 않는다.