• Journal of Korean Physical Therapy Science
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• v.3 no.4
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• pp.147-152
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• 1996

Therapeuticre rehabilitation of young children has often included the use of walker as mobility aids. Traditional walkers have four vertical legs, a horizontal bar in front of child, and horizontal bars on either side which also serve as hand grip. Child pushes it. It is called 'anterior walker'. 'Posterior walker' have been introduced which the child pull along behind himself during ambulation. The purpose of this investigation was to compare specific gait characteristics of children with developmental disability, while they ambulated with anterior and posterior walker. Using the posterior walker, specific gait characteristics improve than using anterior walker.

• Development and Reproduction
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• v.16 no.3
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• pp.169-175
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• 2012

Angelman syndrome (AS) is a neurodevelopmental disorder characterized by intellectual disability and autism. The genetic cause is the absence of UBE3A, an E3 ubiquitin ligase, from the maternal chromosome which can arise from multiple origins. Recently discovered targets of Ube3a are important for activity dependent changes in synaptic transmission and spine morphology. Plasticity studies in an AS mouse model is important for basic plasticity research with regard to understanding protein homeostasis as well as the search for therapeutic targets for the patients. The progress on synaptic plasticity from this unique disorder is reviewed.

• Journal of Interdisciplinary Genomics
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• v.5 no.2
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• pp.24-28
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• 2023

Chromosomal microarray (CMA) is primarily recommended for detecting clinically significant copy number variants (CNVs) in the genetic diagnosis of developmental delay, intellectual disability, autism, and congenital malformations. Prenatal CMA is recommended when a fetus has major congenital malformations. The main principles of CMA can be divided into array comparative genomic hybridization and single-nucleotide polymorphism arrays. In the current CMA platforms, these two principles are combined, and detection of genetic abnormalities including CNVs and absence of heterozygosity is facilitated. In this review, I described practical assessment of CMA testing regarding to laboratory management of CMA, interpretation of CNVs, and special considerations for comprehensive genetic counseling.

• The Journal of the Korea Contents Association
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• v.16 no.10
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• pp.492-502
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• 2016

This study examined the effects of parenting stress on the quality of life in parents of children with disability, and moderating effects of welfare service perception in the process. This study conducted a survey to 327 parents who rear such children in Chungnam, Chungbuk and Daejeon provinces. This study utilized SPSS 18.0 for analysis, and the main results of this study were as follows. First, the level of parenting stress is shown higher level in parents who rear the children with developmental disabilities. The level of welfare service perception and quality of life is shown higher level in parents who rear the children with physical disabilities. Second, common influential factors of life quality were parenting stress, welfare service perception, sex of parents, disability degree and residential area. For parents who rear the children with developmental disabilities, education level of parents and for parents who rear the children with physical disabilities, age of Children show to be influential. Third, welfare service perception is shown to be statistically significant so that moderating effects is found in the relationship between the parenting stress and quality of life. Based on such empirical analysis results, this study suggested concrete and comprehensive working strategies to improve quality of life in parents of children with disabilities.

• Journal of Genetic Medicine
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• v.12 no.1
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• pp.12-18
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• 2015

Malformations of cortical development (MCD) cover a broad spectrum of developmental disorders which cause the various clinical manifestations including epilepsy, developmental delay, and intellectual disability. MCD have been clinically classified based on the disruption of developmental processes such as proliferation, migration, and organization. Molecular genetic studies of MCD have improved our understanding of these disorders at a molecular level beyond the clinical classification. These recent advances are resulted from the development of massive parallel sequencing technology, also known as next-generation sequencing (NGS), which has allowed researchers to uncover novel molecular genetic pathways associated with inherited or de novo mutations. Although an increasing number of disease-related genes or genetic variations have been identified, genotype-phenotype correlation is hampered when the biological or pathological functions of identified genetic variations are not fully understood. To elucidate the causality of genetic variations, in vivo disease models that reflect these variations are required. In the current review, we review the use of NGS technology to identify genes involved in MCD, and discuss how the functions of these identified genes can be validated through in vivo disease modeling.

• Journal of Family Resource Management and Policy Review
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• v.18 no.2
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• pp.103-119
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• 2014

This study focuses on the relationship between time management behavior and parenting stress of mothers with developmentally disabled children. The participants of this study were 162 mothers whose children have developmental disabilities and attend pre-school and social welfare centers for early education. This study investigates the time management behaviors of the participants, and whether these behaviors have an effect on their time management satisfaction and parenting stress. The findings were as follows: 1) The time management behaviors of the participants were lower than average, scoring 2.87 out of 5. The order of dimensional scores from highest to lowest were sequencing, planning, recording habits, evaluating, and setting goals. 2) Time management satisfaction and parenting stress for the participants exhibited a negative correlation. 3) Adaptation behaviors of the children and time management behaviors of the mothers were factors that had significant effects on the mothers' parenting stress. These results showed the importance of time management for mothers with developmentally disabled children.

• Journal of Digital Convergence
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• v.12 no.10
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• pp.485-491
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• 2014

The aim of this study is to suggest development guidelines of educational smart application for the students with development disability based on Universal Design for Learning(UDL). The basic guideline set were organized by analyzing UDL studies on different media. The totally 35 preliminary guidelines which consist of 14 items of contents presentation, 12 items of education strategy and 9 items of education engagement were settled through review of smart contents expert developer and professors in special education. Based on the preliminary guideline, a survey was conducted to determine effective guidelines among end users which consist of the teachers who educate students with disability, parents with disabled children and professors in special education major. 3 categories and 20 guidelines are presented by analyzing survey result through excluding items whose importance factor were lower than average of importance.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.11
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• pp.7501-7507
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• 2015

This study analyzed the rate of unmet dental care service for the disabled who were judged to require the dentistry due to oral health-related problems and those reasons, and also examined the oral health status according to the unmet dentistry. 375 subjects, who were 19 years or older and completed oral health examination and a survey, among 444 responded positive of disability registration after participation in National Health and Nutrition Examination Survey(NHANES), were analyzed. Disability type was classified into 6 kinds(physical disability, brain lesions, sensory defect, developmental disability, mental disorder, endocrine disorder). Participants had 128 of their dental care needs unmet when it was required. 'Financial burden' was the main reason, with the subject of 49.2%, followed by 'lower on the priority scale' were 18.0%. The high frequency and progression permanent teeth caries experiencs and periodontal status of their dental disease were confirmed. In availability aspect of dentistry resources, it is required for using dentistry service smoothly through providing sufficient proper dental care service comparing with the number of the disabled.

• The Journal of Information Systems
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• v.31 no.3
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• pp.47-65
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• 2022

Purpose With the recent development of Big Data and Artificial Intelligence technology, self-driving technology has developed into three stages (partial self-driving) or four stages (conditional self-driving), it is expected to bring a new paradigm to transportation in the city. Although many researchers are researching related technologies, there is no research on self-driving for disabled persons. In this study, the basic research was conducted based on the assumption that the shared self-driving car used by the disabled person is similar to the special transportation currently driving. Design In this study, data analysis and machine learning techniques were utilized to analyze the mobility patterns of disabled persons by type and to search for leading factors affecting the traffic volume of special transportation. Findings The study found that external physical disorders and developmental disorders often visit general welfare centers, internal organ disorders often visit general hospitals, and the elderly and mental disorders have various destinations. In addition, machine learning analysis showed that the main transportation routes for the disabled person use arterial roads and auxiliary arterial roads and that the ratio of building usage-related variables affecting the use of special transportation for a disabled person is high. In addition, the distance to the subway and bus stops was also mentioned as a meaningful variable. Based on these analysis results, it is expected that the necessary infrastructure for shared self-driving cars for disability person traffic will be used as meaningful research data in the future.

• Korean Journal of Forensic Psychology
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• v.12 no.3
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• pp.323-341
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• 2021

This study examined public perceptions of the reasons underlying sentence reduction for defendants convicted of sex crimes against persons with intellectual disability. An online survey was conducted among 522 adults in South Korea. Respondent endorsement of 20 reasons underlying sentence reduction, which were embedded within the respective rulings, and the perceived appropriateness of statutory sentence for the crimes committed were assessed. The results showed that most respondents endorsed the sentence; moreover, those who disagreed underscored the need for more severe punishment. Almost all the respondents perceived the following reasons and explanations unfavorably: impulsiveness caused by sexual arousal or alcohol consumption; an accidental occurrence; and personal characteristics such as defendant age, health condition, socioeconomic status, developmental history, and family background. However, there was a relative agreement in that the damage caused by the incident was relatively minor, or the defendant's reflection and attitude to recover the damage were used as reasons for the reduction. Differences in respondent perceptions of the reasons underlying sentence reduction as a function of gender and educational background were relatively small. However, younger respondents held harsher attitudes toward sentence reduction. The present findings underscore the need to be mindful of victims' statements and the characteristics of persons with intellectual disability while sentencing.