• Title/Summary/Keyword: Development factor

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Targeting of Large-molecule Radiopharmaceuticals across the Blood-brain Barrier Using Endogenous Transport Systems

  • Lee, Hwa-Jeong
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.94-95
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    • 2002

  • Drug targeting to the central nervous system (CNS) is the limiting factor in CNS drug development because most of drug do not cross the brain capillary endothelial wall, which forms the blood-brain barrier (BBB) in vivo. One strategy for drug targeting to the brain is to use endogenous BBB transport systems. (omitted)

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Development of New NMDA Receptor Agonists/Antagonists

  • Park, No-Sang
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.72-74
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    • 2003

  • Excitatory amino acid (EAA) receptor, particularly NMDA receptor, are now known to be one of major transmitter receptors involved in synaptic excitation. Excessive release of EAA neurotransmitter, glutamate, is an important causative factor in the neurodegenerative processes and can cause neuronal damage and cell death. This excitotoxicity has been shown to be $Ca^{++}$ dependent. (omitted)

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CRT competitive strategies towards flat panel displays

  • Sluyterman, A.A.S.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2003.07a
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    • pp.137-141
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    • 2003

  • CRTs can survive in the long run for TV applications, because of their realistic reproduction of live images. CRT technology development has to be directed towards form factor, but also attention has to be paid to the form design of sets. The CRT is the only technology allowing a doubly curved screen surface.

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