• Title/Summary/Keyword: Development factor

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Regulation of Preimplantation Development of Mouse Embryos by Insulin and Tumor Necrosis Factor alpha

  • Gye, Myung-Chan;Han, Hyun-Joo
    • Proceedings of the Korean Society of Developmental Biology Conference
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    • 2001.08a
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    • pp.45-47
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    • 2001
  • 생쥐 착상전 초기배아에서 insulin과 tumor necrosis factor $\alpha$ (TNF$\alpha$)에 의한 배아의 형태 발생, 세포증식, apoptosis 및 MAPK활성의 변화를 조사하였다. Insulin에 의해 형태발생 및 포배당 세포수가 증가되었으며 TNF $\alpha$ 처리시 유의하게 감소하였다. TNT$\alpha$ 전처리시 insulin에 의한 발생 및 세포수 증가 촉진효과가 상쇄되었으며 TNF$\alpha$는 배아내 caspase-3의 활성을 증가시켰다. Insulin은 단시간내에 포배에서 mitogen activated protein kinase (MAPK or Erk1/2)의 활성을 증가시켰다. TNF$\alpha$는 포배내 MAPK의 활성을 감소시켰다. Insulin 처리 전 TNF $\alpha$를 전처리한 경우 insulin에 의한 MAPK 활성의 증가가 상쇄되었다. 배발생을 촉진하는 인슐린 신호전달 과정은 MAPK cascade를 경유하며 TNF $\alpha$를 경유한 신호전달과 Crosstalk이 존재하는 것으로 사료된다.

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Intuition and metacognition in Mathematical Problem Solving Process (수학 문제해결 과정에서의 직관과 메타인지)

  • 이대현;이봉주
    • Journal of Educational Research in Mathematics
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    • v.12 no.2
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    • pp.265-274
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    • 2002
  • The purpose of the paper is to provide the importance of matacognition as a factor to correct the errors generated by the intuition. For this, first of all, we examine not only the role of metacognition in mathematics education but also the errors generated by the intuition in the mathematical problem solving process. Next, we research the possibility of using metacognition as a factor to correct the errors in the mathematical problem solving process via both the related theories about the metacognition and an example. In particular, we are able to acknowledge the importance of the role of metacognition throughout the example in the process of the problem solving It is not difficult to conclude from the study that emphasis on problem solving will enhance the development of problem solving ability via not only the activity of metacognition but also intuitive thinking. For this, it is essential to provide an environment that the students can experience intuitive thinking and metacognitive activity in mathematics education .

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Suppression of the Development of Delayed-Type Hypersnsitivity to Sheep Erythrocytes by Serum from BCG-Infected Mice (BCG 감염(感染)마우스 혈청(血淸)에 의(依)한 지연성(遲延性) 과민반응(過敏反應) 억제(抑制))

  • Lee, Hern-Ku;Kim, Tae-Gon;Ha, Tai-You
    • The Journal of the Korean Society for Microbiology
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    • v.18 no.1
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    • pp.87-90
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    • 1983
  • The immunosuppressive effect of serum from mice heavily infected with BCG(BCG-serum) was evaluated. The delayed-type hypersensitivity reaction to sheep erythrocytes was depressed when BCG-serum was administered both systemically and locally at the same time of challenge. This study shows that serum of animal infected with mycobacteria contains a factor responsible for immunosuppression and factor may be important in understanding the mechanisms of allergy in mycobacteria] infections.

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Research on the Development of Sensing Data and Water Unit Factor Application of Urban Water Demand (센싱데이터와 원단위 산정을 활용한 도시용수 사용량 산정기법에 관한 연구)

  • Kim, Dong-Moon;Kim, Seong-Hoon;Lee, Si-Hyoung;Kim, Eui-Myoung;Park, Jae-Kook
    • Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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    • 2010.04a
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    • pp.347-348
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    • 2010
  • The purpose of this study lies in presenting a methodology to estimate the amount of water to be used in the future by grasping the state of water use in real time based on a statistical analysis using water unit factor application of urban water demand of existing housing, education facilities, and industrial water as well as sensing data by water type. The results of the study would provide in real time the state of water use per water type and the amount of water to be consumed in the future in order to provide basic data for decision-making when planning and managing water facilities based on GIS at times water lacks.

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Development of Chassis Dynamometer Test Modes to Derive the Emission Factors for Light Duty Vehicles (소형자동차 배출계수 산출용 차대동력계 시험모드의 개발)

  • 이영재;김강출;표영덕;선우명호;엄명도
    • Transactions of the Korean Society of Automotive Engineers
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    • v.10 no.6
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    • pp.117-124
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    • 2002
  • For the correct estimation of air pollutant emission from automobiles which is the largest contributor of metropolitan area air pollution, the total pollutant emission from automobiles should be estimated accurately. Nationwide emissions from automobiles, such as CO, HC and NOx, are calculated by using emission factor and total VMT(vehicle miles traveled). The emission factors were derived from the emissions data on chassis dynamometer with test modes which represent the real driving patterns. In the present study, test modes to derive the emission factors for light duty vehicles are developed by using the real driving pattern data for the urban, suburban and express way.

A Study on the Key Performance Factors of Passenger Airbag and Injury Risk Prediction Technique Development (동승석 에어백 핵심 성능 인자 및 상해위험도 예측 기법 개발에 대한 연구)

  • Park, Dongkyou
    • Transactions of the Korean Society of Automotive Engineers
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    • v.21 no.5
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    • pp.130-135
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    • 2013
  • Until now, passenger airbag design is based on the referred car design and many repetitive crash tests have been done to meet the crash performance. In this paper, it was suggested a new design process of passenger airbag. First, key performance factors were determined by analyzing the injury risk effectiveness of each performance factor. And it was made a relationship between injury risk and performance factor by using the response surface model. By using this one, it can be predicted the injury risk of head and neck. Predicted injury risk of optimal design was obtained through this injury risk prediction model and it was verified by FE analysis result within 18% error of head and 9% error of neck. It was shown that a target crash performance can be met by controlling the key performance factors only.

A Study of Fast Contingency Analysis Algorithm (신속한 상정사고해석 알고리즘에 관한 연구)

  • Moon, Young-Hyun
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.34 no.11
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    • pp.421-429
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    • 1985
  • With the rapid increase of contingency cases due to complication of power system, the reduction of computation time in contingency analysis has become more significant than ever before. This paper deals with the development of a fast contingency analysis algorithm by using a matrix decomposition method. The proposed matrix decomposition method of contingency analysis yields an accurate solution by using the original triangular factor table. An outstanding feature of this method is of no need of factor table modification for network changes due to contingency outages. The proposed method is also applicable to multiple contingency analysis withremarkable reduction of computation time. The algorithm has been tested for a number of single and multiple contigencies in 17-bus and 50-bus systems. The numerical results show its applicability to practical power systems.

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A Study On the Single Phase SRM Driver of High Power Factor Connection (단상 SRM의 고역률 구동회로에 관한 연구)

  • Hong, Jeng-Pyo;Lee, Sang-Hun;Park, Sung-Jun;Ahn, Jin-Woo;Kwon, Soon-Jae;Hong, Soon-Ill;Kim, Cheul-U
    • Proceedings of the KIEE Conference
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    • 2001.04a
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    • pp.345-348
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    • 2001
  • In this paper, the development of input power factor and harmonic distortion of line current were showed in the proposed single-stage SRM inverter. It is verified from the experiments that the proposed encoder and logic controller can be a powerful candidate for the practical low cost SRM drive.

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A Study on Calamity Index Evaluation Based on FRAT - Construction Safety - (FRAT을 이용한 재해평가지수 연구 - 건설업을 중심으로 -)

  • Park, Tae-Hyun
    • Journal of the Korea Safety Management & Science
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    • v.9 no.6
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    • pp.31-38
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    • 2007
  • The construction industry by its nature retains higher level of danger where the smallest of error may lead to a major catastrophe endangering many workers and public safety as well as provoke social criticism. With the aid of quantitative statistical data on safety-related calamity analyzed till this day, this paper handled in depth the analysis of diseases other than the accidents, and selected new variable indexes that influence the indirect sections of calamity that are mostly concealed and incorporated them in a new model. For the factor selection of new calamity evaluation model, FRAT(Frequency, Recency, Amount, Type of merchandise/service)technique of customer-related management in marketing was applied, and as for the significance of each factor in the weight selection of variables. Consequently, considering the graveness of the FRAT itself through safety management experts, the related researches must be expanded.

A Study on the Development of Analytic Hierarchy Process Plant Evaluation System for Safety Management (안전관리를 위한 AHP 설비 평가시스템 개발에 관한 연구)

  • Yun, Yeo-Kwon;Cho, Young-Wook;Yang, Kwang-Mo
    • Journal of the Korea Safety Management & Science
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    • v.14 no.3
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    • pp.127-134
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    • 2012
  • Plant safety management that is enforcing introducing more than 95% in domestic manufacturing industry is using total plant efficiency by the evaluation index, and as a result, can see a lot of examples that plant productivity, economy and safety is increased. The efficient safety estimation for a business should analyze an accident data by considering every possible and potential factor. This study's purpose centers plant safety management activities that is management system for plant production and safety efficiency's maximization, plant evaluation system that plant safety management activities factor(reliability, maitainability, safety, service quality) that is enforcing in manufacturing industry can develop evaluation model that can evaluate qualitative activities by quantitative activities in process that maximize plant safety management wishes to do design.