• Proceedings of the Korean Society of Developmental Biology Conference
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• 2003.10a
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• pp.114-114
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• 2003

Epidermal growth factor (EGF) induces well-documented mitogenic and differentiating effects on murine and bovine preimplantation embryos. However, the effects of EGF on apoptosis and implantation-related gene expression in bovine embryos developing in vitro have not been evaluated. The objective of this study was to determine the effects of exogenous EGF in the presence and absence of BSA on the preimplantation development of bovine embryos. In addition, we measured cell number, apoptosis, and expression of apoptosis and implantation-related genes of the blastocysts that developed in these culture conditions. In vitro produced bovine embryos were randomly cultured in the same medium containing 0 or 10 ng/ml EGF in the presence and absence of 0.8% BSA. More 2-cell embryos developed into blastocysts at day 7 when BSA was present than when BSA was absent. The addition of 10 ng/$m\ell$ EGF into the medium did not significantly increase the developmental rate and the cell numbers per blastocyst. However, addition of EGF in the presence of 0.8% BSA significantly reduced the degree of apoptosis in the blastocysts (P<0.01). To investigate whether EGF modulates mRNA expression of apoptosis-related genes, mRNA was prepared from single blastocysts and each preparation was subjected to RT-PCR for Bcl-2 and Bax transcripts. EGF did not alter the relative abundance of Bax gene expression in the presence of BSA, but increase Bcl-2 (P<0.01) The relative abundance of Interferon tau expression was increased by EGF treatment in the presence of BSA. These results suggest that EGF and BSA synergistically enhance Bcl-2 and interferone tau gene expression, which may result in a net increase in viability in bovine embryos.

• Proceedings of the Korean Society of Developmental Biology Conference
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• 2003.10a
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• pp.99-99
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• 2003

Epidermal growth factor (EGF) induces well-documented mitegenic and differentiating effects on murine and bovine preimplantation embryos. However, the effects of EGF on apoptosis and implantation-related gene expression in bovine embryos developing in vitro have not been evaluated. The objective of this study was to determine the effects of exogenous EGF in the presence and absence of BSA on the preimplantation development of bovine embryos. In addition, we measured cell number, apoptosis, and expression of apoptosis and implantation-related genes of the blastocysts that developed in these culture conditions. In vitro produced bovine embryos were randomly cultured in the same medium containing 0 or 10 ng/$m\ell$ EGF in the presence and absence of 0.8% BSA. More 2-cell embryos developed into blastocysts at day 7 when BSA was present than when BSA was absent. The addition of 10 ng/$m\ell$ EGF into the medium did not significantly increase the developmental rate and the cell numbers per blastocyst. However, addition of EGF in the presence of 0.8% BSA significantly reduced the degree of apoptosis in the blastocysts (P< 0.01). To investigate whether EGF modulates mRNA expression of apoptosis-related genes, mRNA was prepared from single blastocysts and each preparation was subjected to RT-PCR for Bcl-2 and Bax transcripts. EGF did not alter the relative abundance of Bax gene expression in the presence of BSA, but increase Bcl-2 (P < 0.01). The relative abundance of Interferon tau expression was increased by EGF treatment in the presence of BSA. These results suggest that EGF and BSA synergistically enhance Bcl-2 and interferone tau gene expression, which may result in a net increase in viability in bovine embryos.

• Journal of Korean Academy of Nursing
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• v.26 no.2
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• pp.345-358
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• 1996

All human health behavior is deeply rooted one's beliefs or value system usually encompassed within the culture in which they live. The Taegyo, based on Oriental folk medicine, is defined as the behavior and self care of pregnant women administered for herself and her fetus(unborn child). Taegyo is believed to be desirable, effective, and healthy behavior by most of Korean pregnant women. It is essential in our contemporary culture, to ascertain what the components of Taegyo are and to integrate them into current, western nursing care, particularly in the area of prenatal care. 910 Korean women were the subjects of this study, who were in a gestation period of pregnancy between 10 weeks to three months postpartum. The subjects were selected by clustered smpling from 10 representative cities in Korea. Data was collected from February 10 to March 30 1995 by a constructed Questionnaire which consisted of 95 items. The questionnaire was developed through three steps such as content analysis, calculation of content validity index, and pretest. Data was analyzed by descriptive statistics and rotated matrix factor analysis with pc-SAS. The mean age of the subjects was 28.9 years : 36.5％ of them were employed and the mean income per month was about 2000 dollars. The component of Taegyo was clustered into five factors such as fetus psychological stability(equity), fetus personality development, maternal-fetal interaction, fetus intellectual development and physical health promotion. The variance of each factor were 23.7％, 8.3％, 4. 7％, 4.1％, and 3.3％ respectively in that order. The Eigen value of each factor was 13.03, 4.57, 2.60, 2.23, and l.83 respectively. It was found that the Taegyo is an unique and holistic self care behavior of Korean pregnant women. Therefore it has been concluded that this study has broadened the understandability of the implications the Taegyo. It is suggested that further studies on the effects of the Taegyo are needed to provide a scientific basis for professional maternity nursing.

• Journal of Aquaculture
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• v.1 no.1
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• pp.53-66
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• 1988

Histological study was conducted to determine the initial treatment time and treatment period of hormone for sex reversal in accordance with gonadal development and sexual differentiation in Oreochromis niloticus. The effects of various concentrations and various treatment periods of 17$\alpha$-methyltestosterone (MT) on sex reversal, growth, and condition factor were also evaluated. Paired primodial gonads were formed 9 days after hatching, when germ cells began their gradual multiplication and development into gonial ones. Sex differentiation of gonads either into ovaries or testes became histologically discernible about 20 days after hatching with formation of ovarian cavity and efferent duct. All feed treated with MT at 15 ppm for 10 days or more produced populations of males $95\%$ or above. All male populations were produced at 15 ppm MT for 40 days, and 30 ppm for 30 and 40 days. Growth of hormone-treated-fish was faster than that of untreated ones and the condition factor of hormone-treated-fish was greater than that of untreated ones 77 days after hatching.

• Journal of Fashion Business
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• v.21 no.4
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• pp.73-89
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• 2017

This research aimed to identify the characteristics of outdoor apparel market for new seniors. To achieve this goal, influence of new seniors' lifestyle and apparel purchase criteria of design preferences of outdoor apparel products were investigated. An online-survey was conducted targeting fifties who have bought outdoor apparel within one year. The collected data were carried out for factor analysis, independent sample T-test, and regression analysis by using SPSS 22.0. Results showed that new seniors' lifestyles were composed of appearance-orientation, well-being diet, well-being exercise, self-development, and challenge-orientation. Purchase criteria of outdoor apparels were factored out as practical, aesthetic, and social. Appearance -orientation and self-development affect aesthetic and social factors. Well-being diet influences all factors of purchase criteria. Challenge -orientation has effect only on social factor. Women favored round-and V-neckline more than men did as well as preferred half and 3/4 long for sleeve. Customers who value practical purchase criteria preferred half-sleeve, zipper, and button-closure designs. In contrast, customers who have aesthetic purchase criteria like round/V-neckline and cap sleeve. Social factor affected high neckline and vivid-tone color preference significantly. As outdoor design for new senior it is critical to introduce differentiation of outdoor brand with various designs combining functionalities of outdoor activities and style looking young and dandy, which is highlighted as trendy and casual, over current outdoor apparels' unified design.

• The Journal of the Korea Contents Association
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• v.12 no.3
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• pp.161-170
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• 2012

Based on the qualitative analysis, 4 factors of dance giftedness were operationally defined and test items were initially developed accordingly. The preliminary test data obtained from 206 dancers was analyzed, using item analysis and a series of reliability analyses. In order to dancer the construct validity, four exploratory factor analyses were conducted for 54 items, resulting in 20 items of 4 factors; physique, dance attitude Expressiveness and creativity, movement ability. A confirmatory factor analysis conducted for 292 dancers to test the goodness-of-fit of 4 factor model revealed a satisfactory level of $x^2$, Q, root mean square residual(RMR), goodness of fit index(GFI), Tucker-Lewis index(TLI), comparative fit index(CFI), root mean square error of approximation(RMSEA). The concurrent and cross validity indices proved the validity of 20 items of 4 factors.

• The Journal of the Korea Contents Association
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• v.17 no.8
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• pp.435-453
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• 2017

The purpose of this study was to develop the Empathy Rating Scale by a third party and examine the validity of the scale. Based on the results of the pilot study, the study 1 focused on developing Empathy Rating Scale by a third party. From the exploratory factor analysis on a total of 15 preliminary items, three fators had been derived: 'Beginning of empathy', 'Process of empathy', 'Result of empathy'. The study 2 identified its validity by confirmatory factor analysis, correlation analysis, and discriminant analysis. Those three factors indicated the reasonable fit index by confirmatory factor addition, this scale identified a significant positive relation with authenticity, emotional clarity, and intimacy. On the other hand, it indicated a negative relation with anxiety attachment and rejection attachment. Therefore, the results indicated that this scale on a total of 11 item has a reliable convergent validity. Finally, implication and limitation of this study were discussed in relation with future studies.

• Journal of Periodontal and Implant Science
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• v.50 no.5
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• pp.303-312
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• 2020

Purpose: The purpose of this study was to evaluate severe periodontitis with tooth loss as a modifiable risk factor for Alzheimer dementia (AD), vascular dementia (VaD), and mixed dementia (MD) using the National Health Insurance Service-National Health Screening Retrospective Cohort database with long-term follow-up over 14 years. Methods: Multivariate Cox hazards regression analysis was applied to a longitudinal retrospective database, which was updated in 2018, to evaluate the association between severe periodontitis with few remaining teeth and dementia after adjusting for potential risk factors, including sociodemographic factors and comorbid diseases. Results: Among 514,866 individuals in South Korea, 237,940 (46.2%) participants satisfying the inclusion criteria were selected. A total of 10,115 age- and sex-matched participants with severe periodontitis and 10,115 periodontally healthy participants were randomly selected and evenly assigned. The results showed that the risks of AD (hazard ratio [HR], 1.08), VaD (HR, 1.24), and MD (HR, 1.16) were significantly higher in patients with severe periodontitis with 1-9 remaining teeth after adjustment for sociodemographic factors, anthropomorphic measurements, lifestyle factors, and comorbidities. Conclusions: Severe periodontitis with few remaining teeth (1-9) may be considered a modifiable risk factor for the development of AD, VaD, and MD in Korean adults.

• Journal of Korean Public Health Nursing
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• v.16 no.2
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• pp.378-387
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• 2002

This study was conducted to investigate the degree of PSI (self-evaluative awareness of problem solving ability) in PMHNP (psychiatric mental health nurse practitioners) and to identified the factors predicting problem solving ability of them, in order to provide basic data for the development of the specific education programs to improve problem solving ability. Data was collected from 355 subjects who have the certificates of PMHNP working in hospitals and public centers. Chun Seok Kyun's instruments (1993) based on the Heppner and Petersen's Problem Solving Inventory (1982) was used to determine PMHNPs' PSI. The results were as follows; 1. The average score of PSI of PMHNP was $2.81\pm0.23$. Of the three factors. there marked the lowest score in the factor 3. personal control $(2.56\pm0.43)$, and the highest score was in the factor 1. problem-solving confidence $(2.95\pm0.34)$. 2. The differences in PSI were significant for degree of education and career in psychiatric settings (p=0.000l, p=0.0187). 3. Job satisfaction was the highest factor predicting PSI of PMHNP$(17.9\%)$. When degree of education, career in psychiatric setting and marital status were added, the total predictors explained $24.3\%$. As a result, it is necessary to conduct further research in relation to the problem-solving process, the development of education program. skill acquisition and measurement of problem solving in nursing practice.

• KDI Journal of Economic Policy
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• v.32 no.4
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• pp.75-114
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• 2010

This paper examines empirically whether information and communication technology(ICT) has improved total factor productivity at industry level in Korea, considering time lag between ICT capital accumulation and improvement of productivity. To evaluate if ICT is pervasive enough to raise productivity, ICT capital stock of Korea is compared with those of advanced economies. From the perspective of aggregate economy, the ICT capital in Korea has increased fast since the mid-1990s and became comparable with advanced economies. However it is mostly attributed to rapid growth of ICT-producing industries. In other industries, ICT capital are still less accumulated than advanced economies. Growth accounting results exhibit that the productivity has risen faster since 2000 in industries using ICT intensively, but looking into specific industries, it is not likely for ICT to be the main factor of productivity improvement except in business service industry. Regression results provide some evidence that ICT is useful in raising productivity only after considerable amount of time allowed. To fully exploit the positive effect of ICT on productivity, it may be necessary for the Korean economy to create institutional environment facilitating complementary innovations as well as ICT captial accumulation.