• 제목/요약/키워드: Development delay

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DENTAL TREATMENT IN A PATIENT WITH ANGELMAN SYNDROME DUE TO UNIPARENTAL DISOMY (편친 이염색체성 엔젤만 증후군(Angelman syndrome) 환자의 치과치료)

  • Park, Sung-Hee;Shin, Teo-Jeon;Hyun, Hong-Keun;Kim, Young-Jae;Kim, Jung-Wook;Lee, Sang-Hoon;Kim, Chong-Chul;Jang, Ki-Taeg
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.12 no.1
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    • pp.11-15
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    • 2016
  • Angelman syndrome is characterized by a partial deficit of paired autosomal chromosome 15, which contains a subunit of the GABA (Gamma-Amino Butyric Acid) receptor. The main clinical characteristics of this syndrome are delayed neuropsychological development, intellectual disability, and speech impairment. The syndrome has oral manifestations such as diastemas, tongue thrusting, sucking swallowing disorder, and excessive chewing behavior. A 3-year-6-month old girl with Angelman syndrome was scheduled for dental treatment. She had multiple caries, but she was poorly cooperative for treatment due to developmental delay and movement disorder, so general anesthesia was considered. The patient with Angelman syndrome was successfully treated under general anesthesia. There were no postoperative complications related to anesthesia and dental treatment. When treating children with this syndrome, the dentist needs to manage their uncooperative behavior and medical problem.

Development of CPLD Technology Mapping Algorithm for Sequential Circuit Improved Run-Time Under Time Constraint (시간제약 조건하에서 순차 회로를 위한 수행시간을 개선한 CPLD 기술 매핑 알고리즘 개발)

  • Yun, Chung-Mo;Kim, Hui-Seok
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.37 no.4
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    • pp.80-89
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    • 2000
  • In this paper, we propose a new CPLD technology mapping algorithm for sequential circuit under time constraints. The algorithm detects feedbacks of sequential circuit, separate each feedback variables into immediate input variable, and represent combinational part into DAG. Also, among the nodes of the DAG, the nodes that the number of outdegree is more than or equal to 2 is not separated, but replicated from the DAG, and reconstructed to fanout-free-tree. To use this construction method is for reason that area is less consumed than the TEMPLA algorithm to implement circuits, and process time is improved rather than TMCPLD within given time constraint. Using time constraint and delay of device the number of partitionable multi-level is defined, the number of OR terms that the initial costs of each nodes is set to and total costs that the$^1$costs is set to after merging nodes is calculated, and the nodes that the number of OR terms of CLBs that construct CPLD is excessed is partitioned and is reconstructed as subgraphs. The nodes in the partitioned subgraphs is merged through collapsing, and the collapsed equations is performed by bin packing so that it fit to the number of OR terms in the CLBs of a given device. In the results of experiments to MCNC circuits for logic synthesis benchmark, we can shows that proposed technology mapping algorithm reduces the number of CLBs by 15.58% rather than the TEMPLA, and reduces process time rather than the TMCPLD.

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Throughput Performance analysis of AMC based on New SNR Estimation Algorithm using Preamble (프리앰블을 이용한 새로운 SNR 추정 알고리즘 기반의 AMC 기법의 전송률 성능 분석)

  • Seo, Chang-Woo;Portugal, Sherlie;Hwang, In-Tae
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.48 no.4
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    • pp.6-14
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    • 2011
  • The fast growing of the number of users requires the development of reliable communication systems able to provide higher data rates. In order to meet those requirements, techniques such as Multiple Input Multiple Out (MIMO) and Orthogonal Frequency Division multiplexing (OFDM) have been developed in the recent years. In order to combine the benefits of both techniques, the research activity is currently focused on MIMO-OFDM systems. In addition, for a fast wireless channel environment, the data rate and reliability can be optimized by setting the modulation and coding adaptively according to the channel conditions; and using sub-carrier frequency, and power allocation techniques. Depending on how accurate the feedback-based system obtain the channel state information (CSI) and feed it back to the transmitter without delay, the overall system performance would be poor or optimal. In this paper, we propose a Signal to Noise Ratio (SNR) estimation algorithm where the preamble is known for both sides of the transciever. Through simulations made over several channel environments, we prove that our proposed SNR estimation algorithm is more accurate compared with the traditional SNR estimation. Also, We applied AMC on several channel environments using the parameters of IEEE 802.11n, and compared the Throughput performance when using each of the different SNR Estimation Algorithms. The results obtained in the simulation confirm that the proposed algorithm produces the highest Throughput performance.

An Adaptive Temporal Suppression for Reducing Network Traffic in Wireless Sensor Networks (무선 센서 네트워크에서 통신량 감소를 위한 적응적 데이터 제한 기법)

  • Min, Joonki;Kwon, Youngmi
    • Journal of the Institute of Electronics and Information Engineers
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    • v.49 no.10
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    • pp.60-68
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    • 2012
  • Current wireless sensor networks are considered to support more complex operations ranging from military to health care which require energy-efficient and timely transmission of large amounts of data. In this paper, we propose an adaptive temporal suppression algorithm which exploits a temporal correlation among sensor readings. The proposed scheme can significantly reduce the number of transmitted sensor readings by sensor node, and consequently decrease the energy consumption and delay. Instead of transmitting all sensor readings from sensor node to sink node, the proposed scheme is to selectively transmit some elements of sensor readings using the adaptive temporal suppression, and the sink node is able to reconstruct the original data without deteriorating data quality by linear interpolation. In our proposed scheme, sensing data stream at sensor node is divided into many small sensing windows and the transmission ratio in each window is decided by the window complexity. It is defined as the number of a fluctuation point which has greater absolute gradient than threshold value. We have been able to achieve up about 90% communication reduction while maintaining a minimal distortion ratio 6.5% in 3 samples among 4 ones.

Development of Intelligent Multiple Camera System for High-Speed Impact Experiment (고속충돌 시험용 지능형 다중 카메라 시스템 개발)

  • Chung, Dong Teak;Park, Chi Young;Jin, Doo Han;Kim, Tae Yeon;Lee, Joo Yeon;Rhee, Ihnseok
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.37 no.9
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    • pp.1093-1098
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    • 2013
  • A single-crystal sapphire is used as a transparent bulletproof window material; however, few studies have investigated the dynamic behavior and fracture properties under high-speed impact. High-speed and high-resolution sequential images are required to study the interaction of the bullet with the brittle ceramic materials. In this study, a device is developed to capture the sequence of high-speed impact/penetration phenomena. This system consists of a speed measurement device, a microprocessor-based camera controller, and multiple CCD cameras. By using a linear array sensor, the speed-measuring device can measure a small (diameter: up to 1 2 mm) and fast (speed: up to Mach 3) bullet. Once a bullet is launched, it passes through the speed measurement device where its time and speed is recorded, and then, the camera controller computes the exact time of arrival to the target during flight. Then, it sends the trigger signal to the cameras and flashes with a specific delay to capture the impact images sequentially. It is almost impossible to capture high-speed images without the estimation of the time of arrival. We were able to capture high-speed images using the new system with precise accuracy.

Development of penetration rate model and optimum operational conditions of shield TBM for electricity transmission tunnels (터널식 전력구를 위한 순굴진율 모델 개발 및 이를 활용한 쉴드TBM 최적운전 조건 제안)

  • Kim, Jeong-Ju;Ryu, Hui-Hwan;Kim, Gyeong-Yeol;Hong, Seong-Yeon;Jeong, Ju-Hwan;Bae, Du-San
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.22 no.6
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    • pp.623-641
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    • 2020
  • About 5 km length of tunnels were constructed by mechanized tunnelling method using closed type shield TBM. In order to avoid construction delay problems for ensuring timely electricity transmission, it is necessary to increase the prediction accuracy of the excavation process involving machines according to rock mass types. This is important to corroborate the project duration and optimum operation for various considerations involved in the machine. So, full-scale tunnelling tests were performed for developing the advance rate model to be appropriately used for 3.6 m diameter shield TBM. About 100 test cases were established and performed using various operational parameters such as thrust force and rotational speed of cuttterhead in representative uniaxial compressive strengths. Accordingly, relationships between normal force and penetration depth and, between UCS and torque were suggested which consider UCS and thrust force conditions according to weathered, soft, hard rocks. Capacity analysis of cutterhead was performed and optimum operational conditions were also suggested based on the developed model. Based on this study, it can be expected that the project construction duration can be reduced and users can benefit from the provision of earlier service.

A Risk Factor Detour Multi-Path Routing Scheme in Wireless Multimedia Sensor Networks (무선 멀티미디어 센서 네트워크 환경에서 위험요소 우회 다중 경로 라우팅 기법)

  • Hwang, Donggyo;Son, In-Goog;Park, Junho;Seong, Dong-Ook;Yoo, Jaesoo
    • The Journal of the Korea Contents Association
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    • v.13 no.1
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    • pp.30-39
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    • 2013
  • In recent years, with the development of devices to collect multimedia data such as small CMOS camera sensor and micro phone, studies on wireless multimedia sensor network technologies and their applications that extend the existing wireless sensor network technologies have been actively done. In such applications, various basic schemes such as the processing, storage, and transmission of multimedia data are required. Especially, a security for real world environments is essential. In this paper, in order to defend the sniffing attack in various hacking techniques, we propose a multipath routing scheme for physically avoiding the data transmission path from the risk factors. Our proposed scheme establishes the DEFCON of the sensor nodes that are geographically close to risk factors and the priorities according to the importance of the data. Our proposed scheme performs risk factor detour multipath routing through a safe path considering the DEFCON and data priority. Our experimental results show that although our proposed scheme takes the transmission delay time by about 5% over the existing scheme, it reduces the eavesdropping rate that can attack and intercept data by the risk factor by about 18%.

Effect the I-T curve and electrical characteristic of fuse elements by plated tin thickness (주석 도금 두께에 따른 퓨즈 가용체의 I-T 커브 및 전기적 특성의 영향)

  • Jin, Sang-Jun;Kim, Eun-Min;Youn, Jae-Seo;Lee, Ye-Ji;Noh, Seong-Yeo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.6
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    • pp.80-87
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    • 2018
  • In recent years, due to the spread of various renewable energy power sources and the pursuit of high efficiency and low-power consumption, not only trends in the electric power industry but also the consumption, control methods, and characteristics are diversified. However, in this diversified electric power industry, the fuse (which is the core part responsible for safety) has not developed significantly in classical operation mode, and thus, fires continue to occur. In this paper, the effects of low melting-point metal plating and high melting-point metal plating on operating characteristics and IT curve movement of the fuse are investigated in a cartridge fuse, which is a classic fuse manufacturing method. The effects of plating on the thickness of the fuse are investigated, and various operating characteristics of the fuse are implemented. In addition, it is suggested that the plating of the low melting-point metal moves the rated current line of the fuse to a low rating, and moves operating characteristics to characteristics of delay operation. It is possible to design various operating characteristics using this characteristic.

Development of a self-leveling system for the bucket of an agricultural front-end loader using an electro hydraulic proportional valve and a tilt sensor (전자유압 비례밸브와 경사센서를 이용한 농용 프론트 로더 버켓 능동수평유지 시스템 개발)

  • Lee, Chang Joo;Ha, Jong Woo;Choi, Deok Su;Kim, Hak Jin
    • Journal of Drive and Control
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    • v.12 no.4
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    • pp.60-70
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    • 2015
  • A front-end loader (FEL) mounted on an agricultural tractor is one of the most commonly used implements for farm work. However, when the tractor carries material using the bucket attached to the FEL on a sloping ground, the materials can spill or roll back over the operator due to the tilted body, thereby requiring the bucket surface to remain level at a constant value regardless of varying slopes. In this study, an active system for controlling the angle of the FEL bucket on a tractor based on the real-time measurement of ground slopes was developed to enable the bucket to constantly remain level. A FEL simulator operated based on an electro hydraulic proportional valve (EHPV) was constructed in the laboratory to develop a proportional-integral-derivative (PID) controller forming a virtual electronic control unit (ECU) on the computer, which could automatically adjust the bucket angles depending on varying input angles while sending SAE-J1939 associated messages via CAN BUS to the EHPV. The different parameter values for the PID controller due to the gravity effect of the bucket were determined using a manual PID tuning method while assuming that the tractor travels on either an ascending slope or a descending slope. The developed PID control-based self-leveling system showed a mean of steady-state errors of within $1^{\circ}$ and a mean of delayed times of ~ 0.8s when the step input of $+20^{\circ}$ was given, implying that the developed system and control algorithm would be effective in maintaining the bucket angle at a certain value. Future studies include the improvement of the control algorithm to reduce such a time delay as well as the application of the developed algorithm to the FEL mounted on a tractor tested at a testing ground.

Mechanistic Analysis of Taxol-induced Multidrug Resistance in an Ovarian Cancer Cell Line

  • Wang, Ning-Ning;Zhao, Li-Jun;Wu, Li-Nan;He, Ming-Feng;Qu, Jun-Wei;Zhao, Yi-Bing;Zhao, Wan-Zhou;Li, Jie-Shou;Wang, Jin-Hua
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.9
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    • pp.4983-4988
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    • 2013
  • Objectives: To establish a taxol-resistant cell line of human ovarian carcinoma (A2780/Taxol) and investigate its biological features. Methods: The drug-resistant cell line (A2780/Taxol) was established by continuous stepwise selection with increasing concentrations of Taxol. Cell morphology was assessed by microscopy and growth curves were generated with in vitro and in vivo tumor xenograft models. With rhodamine123 (Rh123) assays, cell cycle distribution and the apoptotic rate were analyzed by flow cytometry (FCM). Drug resistance-related and signal associated proteins, including P-gp, MRPs, caveolin-1, PKC-${\alpha}$, Akt, ERK1/2, were detected by Western blotting. Results: A2780/Taxol cells were established with stable resistance to taxol. The drug resistance index (RI) was 430.7. Cross-resistance to other drugs was also shown, but there was no significant change to radioresistance. Compared with parental cells, A2780/Taxol cells were significantly heteromorphous, with a significant delay in population doubling time and reduced uptake of Rh123 (p<0.01). In vivo, tumor take by A2780 cells was 80%, and tumor volume increased gradually. In contrast, with A2780/Taxol cells in xenograft models there was no tumor development. FCM analysis revealed that A2780/Taxol cells had a higher percentage of G0/G1 and lower S phase, but no changes of G2 phase and the apoptosis rate. Expression of P-gp, MRP1, MRP2, BCRP, LRP, caveolin-1, PKC-${\alpha}$, Phospho-ERK1/2 and Phospho-JNK protein was significantly up-regulated, while Akt and p38 MARK protein expression was not changed in A2780/Taxol cells. Conclusion: The A2780/Taxol cell line is an ideal model to investigate the mechanism of muti-drug resistance related to overexpression of drug-resistance associated proteins and activation of the PKC-${\alpha}/ERK$ (JNK) signaling pathway.