• Journal of Korea Trade
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• v.25 no.5
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• pp.58-73
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• 2021

Purpose - In the context of economic globalization and the continuous development of international trade, as countries around the sea peninsula, port construction is particularly important. Based on the research on the influencing factors of port logistics development based on the allocation analysis, QCA (Qualitative Comparative Analysis) provides the basis for the planning and policy of port logistics development and has important theoretical value and practical significance for improving the level of port logistics management, reducing logistics operating costs and increasing economic benefits. In the tide of global integration for the development of port logistics, promote the growth of foreign trade economy of the city. It is also of great significance to the development and progress of commerce and trade. Design/methodology - Based on the relevant data samples of various ports in South Korea, this paper uses fsQCA (fuzzy set Qualitative Comparative Analysis) to integrate and analyze the influence mechanism of port logistics development and extracts five influencing factors of port logistics development, including the port's scale and infrastructure in the hard environment, port-neighboring enterprises in the soft environment, hinterland economy and government support. Findings - The five factors are unable to separately constitute the necessary and sufficient conditions of port logistics development, only a combined model can influence lake port logistics development. The scale and infrastructure of the port itself and port-neighboring ring enterprises are the main core conditions, which work together on the port, affect the throughput capacity of the port, and promote the development of port logistics. When the port-neighboring enterprises are not complete and the scale is low, the growth of port throughput will be restrained and the development of port logistics will be affected, whether the hinterland economic benefits are general, the development of port-neighboring enterprises is insufficient, or the government supports are limited. Originality/value - Through the research on the development of port logistics in South Korea from the perspective of configuration, this paper finds the configuration influence of hard environment and soft environment on the development of port logistics, which has important theoretical and practical significance for better promoting the development of port logistics in South Korea.

• Journal of Animal Reproduction and Biotechnology
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• v.36 no.1
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• pp.35-44
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• 2021

A pregnancy diagnosis is an important standard for control of livestock's reproduction in paricular dairy cattle. High reproductive performance in dairy animals is a essential condition to realize of high life-time production. Pregnancy diagnosis is crucial to shortening the calving interval by enabling the farmer to identify open animals so as to treat or re-breed them at the earliest opportunity. MicroRNAs are short RNA molecules which are critically involved in regulating gene expression during both health and disease. This study is sought to establish the feasible of circulating miRNAs as biomarkers of early pregnancy in cattle. We applied Illumina small-RNA sequencing to profile miRNAs in plasma samples collected from 12 non-pregnant cows ("open" cows: samples were collected before insemination (non-pregnant state) and after pregnancy check at the indicated time points) on weeks 0, 4, 8, 12 and 16. Using small RNA sequencing we identified a total of 115 miRNAs that were differentially expressed weeks 16 relative to non-pregnancy ("open" cows). Weeks 8, 12 and 16 of pregnancy commonly showed a distinct increase in circulating levels of miR-221 and miR-320a. Through genome-wide analyses we have successfully profiled plasma miRNA populations associated with pregnancy in cattle. Their application in the field of reproductive biology has opened up opportunities for research communities to look for pregnancy biomarker molecules in dairy cattle.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2003.10a
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• pp.128-129
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• 2003

• Proceedings of the Korean Nuclear Society Conference
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• 2005.10a
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• pp.316-317
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• 2005

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2017.10a
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• pp.95-96
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• 2017

• Proceedings of the Korean Society of Crop Science Conference
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• 2020.06a
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• pp.135-135
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• 2020

• Molecules and Cells
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• v.26 no.5
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• pp.443-453
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• 2008

The Bric-a-brac, Tramtrack, Broad-complex (BTB) domain is a protein-protein interaction domain that is found in many zinc finger transcription factors. BTB containing proteins play important roles in a variety of cellular functions including regulation of transcription, regulation of the cytoskeleton, protein ubiquitination, angiogenesis, and apoptosis. Here, we report the cloning and characterization of a novel human gene, KLHL31, from a human embryonic heart cDNA library. The cDNA of KLHL31 is 5743 bp long, encoding a protein product of 634 amino acids containing a BTB domain. The protein is highly conserved across different species. Western blot analysis indicates that the KLHL31 protein is abundantly expressed in both embryonic skeletal and heart tissue. In COS-7 cells, KLHL31 proteins are localized to both the nucleus and the cytoplasm. In primary cultures of nascent mouse cardiomyocytes, the majority of endogenous KLHL31 proteins are localized to the cytoplasm. KLHL31 acts as a transcription repressor when fused to GAL4 DNA-binding domain and deletion analysis indicates that the BTB domain is the main region responsible for this repression. Overexpression of KLHL31 in COS-7 cells inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE). KLHL31 also significantly reduces JNK activation leading to decreased phosphorylation and protein levels of the JNK target c-Jun in both COS-7 and Hela cells. These results suggest that KLHL31 protein may act as a new transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions.

• Atmosphere
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• v.32 no.2
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• pp.87-101
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• 2022

In this paper, the performance improvement for the new KMA's Climate Prediction System (GloSea6), which has been built and tested in 2021, is presented by assessing the bias distribution of basic variables from 24 years of GloSea6 hindcasts. Along with the upgrade from GloSea5 to GloSea6, the performance of GloSea6 can be regarded as notable in many respects: improvements in (i) negative bias of geopotential height over the tropical and mid-latitude troposphere and over polar stratosphere in boreal summer; (ii) cold bias of tropospheric temperature; (iii) underestimation of mid-latitude jets; (iv) dry bias in the lower troposphere; (v) cold tongue bias in the equatorial SST and the warm bias of Southern Ocean, suggesting the potential of improvements to the major climate variability in GloSea6. The warm surface temperature in the northern hemisphere continent in summer is eliminated by using CDF-matched soil-moisture initials. However, the cold bias in high latitude snow-covered area in winter still needs to be improved in the future. The intensification of the westerly winds of the summer Asian monsoon and the weakening of the northwest Pacific high, which are considered to be major errors in the GloSea system, had not been significantly improved. However, both the use of increased number of ensembles and the initial conditions at the closest initial dates reveals possibility to improve these biases. It is also noted that the effect of ensemble expansion mainly contributes to the improvement of annual variability over high latitudes and polar regions.

• Journal of Agricultural Extension & Community Development
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• v.11 no.2
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• pp.321-341
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• 2004

The purpose of this study was to examine leadership theory to develop leadership of rural leaders. Specific objectives of the study were 1) to examine the general development and trends of leadership theory. 2) to examine recent trends of leadership theory, 3) to examine leadership development of rural Korea. To pursue this purpose literature review was carried out. Based on the results of this study, the following were suggested. 1) Developing leadership of rural leaders was one of the essential factors for rural development. 2) There were differences in leadership according to situation and times. 3) New leadership will be required for future development of rural Korea.

• International Journal of Knowledge Content Development & Technology
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• v.1 no.2
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• pp.43-51
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• 2011

Recently, increasing demand for teacher professional development and significant advances in information and communication technologies has led to a proliferation of online professional development. In spite of online professional development's popularity and advantages, research indicates that there is a concern of considerably high dropout rates of online learners. Therefore, to reduce the dropout rates of the learners, this paper is designed to help teachers identify professional development opportunities that are tailored to their needs as well as successfully complete these learning experiences. To achieve the purpose of the study, the paper explores the considerations for evaluating the characteristics of online learners and online professional development. Using these evaluations, this paper provides practical strategies for helping elementary and secondary education teachers successfully complete online professional development without dropping out an online course.