• Title/Summary/Keyword: Detection platform

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Epigenetic Regulation of Human Riboflavin Transporter 2(hRFT2) in Cervical Cancers from Uighur Women

  • Ma, Jun-Qi;Kurban, Shajidai;Zhao, Jun-Da;Li, Qiao-Zhi;Hasimu, Ayshamgul
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.6
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    • pp.2485-2489
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    • 2014
  • In the present study, we studied the hypermethylation of the human riboflavin transporter 2 (hRFT2) gene and regulation of protein expression in biopsies from resected tissues from Uighur cervical squamous cell carcinoma (CSCC) patients and their neighboring normal tissues. hRFT2 gene promoter region methylation sequences were mapped in cervical cancer cell line SiHa by bisulfite-sequencing PCR and quantitative detection of methylated DNA from 30 pairs of Uighur's CSCCs and adjacent normal tissues by MassARRAY (Sequenom, San Diego, CA, USA) and hRFT2 protein expression was analyzed by immunohistochemistry. In SiHa, we identified 2 CG sites methylated from all of 12CpG sites of the hRFT2 gene. Analysis of the data from quantitative analysis of single CpG site methylation by Sequenom MassARRAY platform showed that the methylation level between two CpG sites (CpG 2 and CpG 3) from CpG 1~12 showed significant differences between CSCC and neighboring normal tissues. However, the methylation level of whole target CpG fragments demonstrated no significant variation between CSCC ($0.476{\pm}0.020$) and neighboring normal tissues ($0.401{\pm}0.019$, p>0.05). There was a tendency for translocation the hRFT2 proteins from cytoplasm/membrane to nucleus in CSCC with increase in methylation of CpG 2 and CpG 3 in hRFT2gene promoter regions, which may relate to the genesis of CSCC. Our results suggested that epigenetic modifications are responsible for aberrant expression of the hRFT2 gene, and may help to understand mechanisms of cervical carcinogenesis.

Addressing Mobile Agent Security through Agent Collaboration

  • Jean, Evens;Jiao, Yu;Hurson, Ali-R.
    • Journal of Information Processing Systems
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    • v.3 no.2
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    • pp.43-53
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    • 2007
  • The use of agent paradigm in today's applications is hampered by the security concerns of agents and hosts alike. The agents require the presence of a secure and trusted execution environment; while hosts aim at preventing the execution of potentially malicious code. In general, hosts support the migration of agents through the provision of an agent server and managing the activities of arriving agents on the host. Numerous studies have been conducted to address the security concerns present in the mobile agent paradigm with a strong focus on the theoretical aspect of the problem. Various proposals in Intrusion Detection Systems aim at securing hosts in traditional client-server execution environments. The use of such proposals to address the security of agent hosts is not desirable since migrating agents typically execute on hosts as a separate thread of the agent server process. Agent servers are open to the execution of virtually any migrating agent; thus the intent or tasks of such agents cannot be known a priori. It is also conceivable that migrating agents may wish to hide their intentions from agent servers. In light of these observations, this work attempts to bridge the gap from theory to practice by analyzing the security mechanisms available in Aglet. We lay the foundation for implementation of application specific protocols dotted with access control, secured communication and ability to detect tampering of agent data. As agents exists in a distributed environment, our proposal also introduces a novel security framework to address the security concerns of hosts through collaboration and pattern matching even in the presence of differing views of the system. The introduced framework has been implemented on the Aglet platform and evaluated in terms of accuracy, false positive, and false negative rates along with its performance strain on the system.

Compact AUV platform system designed for the experiment of underwater multi-agent development

  • Watanabe, Keisuke
    • 제어로봇시스템학회:학술대회논문집
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    • 2005.06a
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    • pp.2036-2041
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    • 2005
  • The underwater multi-agent technology has many potential for the various activities related to ocean development/conservation in the near future. For example, in such fields as water pollution investigation, aquaculture control, or coral reef research, we feel a growing need for a system that realizes underwater continuous monitoring in the wide rang e. In this case, the target monitoring area will be sliced planar hierarchically toward the depth as monitoring layers, and many AUVs arranged on each layer track the given trajectory and gather various environmental information continuously, with communicating each other in the layer or with other layers. To realize those systems we need to develop AUV multi-agent technologies. So we are now building basic systems for basin experiment for the development of AUV multi-agent behavior. We must experience many situations and problems to be solved for the development of its elemental technologies by using real systems as well as our computer simulations. In this paper we introduce our concept of the experiment in the near future and the hardware/software design of our two types of handy AUVs and ultrasound ranging/communication system for that experiment. One AUV is designed using a 17inches-diameter glass sphere with DOS/V and RT-Linux based subsystems, which is intended to use not only in the basin but also in the calm real sea. The other AUV is designed for the basin experiment using a 7inches-diameter acrylic sphere with low-cost embedded system with SH-2 based subsystems. The basin experiment to verify the basic AUV facilities and ultrasound ranging for position detection was carried out.

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Omni-directional Vision SLAM using a Motion Estimation Method based on Fisheye Image (어안 이미지 기반의 움직임 추정 기법을 이용한 전방향 영상 SLAM)

  • Choi, Yun Won;Choi, Jeong Won;Dai, Yanyan;Lee, Suk Gyu
    • Journal of Institute of Control, Robotics and Systems
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    • v.20 no.8
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    • pp.868-874
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    • 2014
  • This paper proposes a novel mapping algorithm in Omni-directional Vision SLAM based on an obstacle's feature extraction using Lucas-Kanade Optical Flow motion detection and images obtained through fish-eye lenses mounted on robots. Omni-directional image sensors have distortion problems because they use a fish-eye lens or mirror, but it is possible in real time image processing for mobile robots because it measured all information around the robot at one time. In previous Omni-Directional Vision SLAM research, feature points in corrected fisheye images were used but the proposed algorithm corrected only the feature point of the obstacle. We obtained faster processing than previous systems through this process. The core of the proposed algorithm may be summarized as follows: First, we capture instantaneous $360^{\circ}$ panoramic images around a robot through fish-eye lenses which are mounted in the bottom direction. Second, we remove the feature points of the floor surface using a histogram filter, and label the candidates of the obstacle extracted. Third, we estimate the location of obstacles based on motion vectors using LKOF. Finally, it estimates the robot position using an Extended Kalman Filter based on the obstacle position obtained by LKOF and creates a map. We will confirm the reliability of the mapping algorithm using motion estimation based on fisheye images through the comparison between maps obtained using the proposed algorithm and real maps.

Development of an Intelligent Software Programmable Logic Controller for IEC1131-3 International Standard Languages (IEC1131-3 표준언어 처리를 위한 지능적 소프트웨어 PLC 개발)

  • Cho, Young-Im
    • Journal of the Korean Institute of Intelligent Systems
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    • v.14 no.2
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    • pp.207-215
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    • 2004
  • The PLC programming by IEC1131-3 is hard to handle to ordinary users as well as professionals. Also it has not a generality, so that it couldn't be debugging some logic errors easily. In order to be adapted for such environment, In this paper, I have developed the ISPLC(Intelligent Agent System based Software Programmable Logic Controller). In ISPLC system, LD programmed by a user is converted to the C code which can be used in a commercial editor such as Visual C++. The detection of logical errors in C code is more effective than PLC programming itself. ISPLC provides the GUI-based interface in web environment and an easy programming platform to such beginners as well as professionals. The study of code conversion of LD to IL as well as IL to C is firstly tried in the world as well as KOREA. To show the effectiveness of the developed system, I applied it to a practical case, a real time traffic control system. ISPLC is minimized the error debugging and programming time owing to be supported by windows application programs.

Home Security System Based on IoT (IoT 기반 홈 보안 시스템)

  • Kim, Kang-Chul;Wang, Ding-Hua;Han, Seok-Bung
    • The Journal of the Korea institute of electronic communication sciences
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    • v.12 no.1
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    • pp.147-154
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    • 2017
  • This paper aims to build a home security system based on IoT to monitor a home on a mobile phone. The system consists of data gathering sensors, camera, gateway and Xively platform. The Raspberry Pi collects data from the three sensors and sends the data to Xively, and sends the video stream of home to a client in a smart phone through a internet. The servers are composed of Xively, socket server in Raspberry Pi and E-mail server in Google. The proposed system transmits e-mail, text message, and video stream when there are motion, fire, and gas leakage, and can control the gas valve through Raspberry Pi. The experimental results show that a user gets 'emergency E-mail' and text message and watches the video stream of the home through WIFI or LTE on a smart phone.

Design and Implementation of M2M-based Smart Factory Management Systems that controls with Smart Phone (스마트폰과 연동되는 M2M 기반 스마트 팩토리 관리시스템의 설계 및 구현)

  • Park, Byoung-Seob
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.4
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    • pp.189-196
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    • 2011
  • The main issues of the researches are monitoring environment such as weather or temperature variation and natural accident, and sensor gateways which have mobile device, applications for mobile health care. In this paper, we propose the SFMS(Smart Factory Management System) that can effectively monitor and manage a green smart factory area based on M2M service and smart phone with android OS platform. The proposed system is performed based on the TinyOS-based IEEE 802.15.4 protocol stack. To validate system functionality, we built sensor network environments where were equipped with four application sensors such as Temp/Hum, PIR, door, and camera sensor. We also built and tested the SFMS system to provide a novel model for event detection systems with smart phone.

Nondestructive sensing technologies for food safety

  • Kim, M.S.;Chao, K.;Chan, D.E.;Jun, W.;Lee, K.;Kang, S.;Yang, C.C.;Lefcourt, A.M.
    • 한국환경농학회:학술대회논문집
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    • 2009.07a
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    • pp.119-126
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    • 2009
  • In recent years, research at the Environmental Microbial and Food Safety Laboratory (EMFSL), Agricultural Research Service (ARS) has focused on the development of novel image-based sensing technologies to address agro-food safety concerns, and transformation of these novel technologies into practical instrumentation for industrial implementations. The line-scan-based hyperspectral imaging techniques have often served as a research tool to develop rapid multispectral methods based on only a few spectral bands for rapid online applications. We developed a newer line-scan hyperspectral imaging platform for high-speed inspection on high-throughput processing lines, capable of simultaneous multiple inspection algorithms for different agro-food safety problems such as poultry carcass inspection for wholesomeness and apple inspection for fecal contamination and defect detection. In addition, portable imaging devices were developed for in situ identification of contamination sites and for use by agrofood producer and processor operations for cleaning and sanitation inspection of food processing surfaces. The aim of this presentation is to illustrate recent advances in the above agro.food safety sensing technologies.

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A bio-sensor SoC Platform Using Carbon Nanotube Sensor Arrays (CNT 배열을 이용한 bio-sensor SoC 설계)

  • Chung, In-Young
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.45 no.12
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    • pp.8-14
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    • 2008
  • A fully CMOS-integrated carbon nanotube (CNT) sensor array is proposed. After the sensor chip is fabricated in commercial CMOS process, the CNTs network is formed on the top of the fabricated sensor chip through the room-temperature post-CMOS processes. When the resistance of the CNT is changed by the chemical reaction, the read-out circuit in the chip measures the charging time of the $R_{CNT}$-Capacitor. finally the information of measured frequency is converted to a digital code. The CMOS sensor chip was fabricated by standard 0.18um technology and the size of the $8{\times}8$ sensor array is $2mm{\times}2mn$. We have carried out an experiment detecting the biochemical material, glutamate, using this sensor chip. From the experiment the CMOS sensor chip shows the feasibility of sensor for the simultaneous detection of the various target materials.

Web contents deformation detection method by BHO (BHO 이용한 웹 컨텐츠 변조 탐지 방법)

  • Mo, Jeong-Hoon;Chung, Man-Hyun;Cho, Jae-Ik;Moon, Jong-Sub
    • Journal of Advanced Navigation Technology
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    • v.15 no.4
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    • pp.655-663
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    • 2011
  • Recently, with improvement of internet service technology, web service has been affecting the environment for computing user. Not only current events, economics, game, entertainment, but also personal financial system is processed by web pages through internet. When data transmission is implemented on the internet, webpage acquire text form code and transform them to DOM information, and then shows processed display to user by web browser. However, those information are not only easily accessed by diversified route, but also easily deformed by intentional purpose. Furthermore, it is also possible to acquire logon information of users and certification information by detouring security mechanism. Therefore, this dissertation propose the method to verify integrity of web contents by using BHO which is one of the Add-On program based on MS Internet Explorer platform which is one of major web browser program designed by MicroSoft to detect any action of webpage deformation.