• 건축역사연구
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• 제11권3호
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• pp.105-120
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• 2002

Eight drawings of Sukcheon-je-a-do are the architectural drawings of the government offices. These were drawn in the representation of Sabang-jeondo-myobeob. Sabang-jeondo-myobeob is one of Korean traditional drawing type, that is constructed with turned-over elevations drawn on the site plan. The analytic observation viewed in the iconographical diagrams of eight drawings led me following conclusions. First, the most typical expression of Sabang-jeondo-myobeob can be summarized as the combination of three elevations toward the inside and one elevation toward the outside. The former is expression of territoriality, and the latter is expression of the facade. Second, in Sabang-jeondo-myobeob both elevations of crosswise direction and of lengthwise direction are described at the viewpoint of eye level. And they center around the courtyards with intent to describe the relation between buildings and the outdoor space. Third, the facade of pavilions, disposed on the crosswise direction in Sabang-jeondo-myobeob, are described with the both viewpoint of down-view and up-view. It is the expression peculiar to Korean traditional drawings, that describes the depth and richness on the facade of traditional wooden architecture. Fourth, some pavilions and landscapes are described in Pyonghaeng-saseon-dobeob, that is familiar drawing type in the Korean traditional paintings. From this expression we can deduce that the traditional architectural drawings such as Sukcheon-je-a-do were constructed by the traditional landscape painters.

• 복식
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• 제52권7호
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• pp.13-25
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• 2002

The purpose of this study is to develope a creative expression technique in fashion illustration through analyzing applied techniques of the elements related to creative expressions in fashion illustrations. They were investigated in view of line, form, texture, color, space and the results were summarized as follows. In the creative expression using line in the fashion illustration. emotional effects of line created by specific character of mediums and duplicated lines have been applied to visualize movements of the objects. In shape, the transformed figure by destructing. covering or eliminating a part of the figure or the dress has been adapted. In texture. the invented texture reconstructed from actual texture has been applied, collage technique. computer graphic being used to give various images of texture. The creative expressions using color have been achieved by the shading. and spreading effects and the symbolic meaning of color for creating a spatiality in a picture plane and to give emotional effects and visual concentricity. In space, the color perspective together with detailed description. the combination of various points of view and liner perspective have been used to create depth and illusional space in pictorial plane.

• 한국의상디자인학회지
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• 제17권2호
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• pp.93-109
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• 2015

Advent of diverse media and advancement in digital technology significantly affected our perception of time and space. By utilizing digital media actively, fashion illustration has come to go beyond the limitation on conventional perspective expression. This study aims to examine the phenomenon of deconstruction of perspective in fashion illustration, and to analyze a variety of space expressions and effects of visual expression in fashion illustration. By way of literature research for the study, theoretical data are reviewed about basic concepts of conventional perspective and the characteristics and aesthetic concept of perspective deconstruction expression in visual art. By way of an empirical study, fashion illustrations that represent the deconstruction of perspective are classified and analyzed characteristics and image effects of such expressions. Deconstruction of perspective in fashion illustration find in expression of spaces by means of multi-space, multi-layer space, reverse perspective, perspective through the exaggeration, multi-perspective space, and panoramic visual condition. Fashion illustration expresses visual confusion or fantasy rather than creating realistic spaces that have utilized reasonable perspective. Fashion illustration is moving toward a trait with disharmony and an in-depth visionary space by overlapping or mixing spaces differing from each other, and by means of such peculiar and unrealistic expressions, unfamiliar images are created.

• Journal of Gastric Cancer
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• 제5권1호
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• pp.34-39
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• 2005

목적: KLF6는 모든 조직에서 발현되고 있는 zinc finger를 가진 종양억제유전자로 인체 여러 암에서 불활성화되어 있다. 연구자들은 KLF6 단백의 발현 변화가 위암의 발생에 관여하는 지를 알아보고자 하였다. 대상 및 방법: 85예의 파라핀 포매된 위암조직에서 암세포들으 각각 3군데에서 펀치하여 새로운 파라핀 블록으로 옮겨 위암의 tissue microarray를 제작하였다. Tissue microarray 절편에서 KLF6 단백에 대한 항체로 면역화학염색을 실시한 후 발현 양상을 병리 지표들인 조직학적 소견, 침습 정도, 림프절 전이 및 복막파종 등과의 연관성을 조사하였다. 결과: KLF6 단백은 위점막의 표면과 소와 상피세포에서 주로 발현되고 있었고 85예 중 28예($28.9\%$)에서 발현 소실이 관찰되었다. 흥미롭게도 KLF6 단백의 발현 소실은 림프절 전이와 통계적으로 연관성이 있었으나 조직학적 소견, 침습 정도와 복막파종과는 연관성이 없었다. 결론: 이러한 소견들은 KLF6 단백의 발현 소실이 위장관 상피세포의 비정상적인 성장과 분화를 유도하고 위암의 발생 및 진행에 관여한다는 것을 의미한다.

• Journal of Gastric Cancer
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• 제6권1호
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• pp.25-30
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• 2006

목적: EphB2 수용체는 티로신 키나제 수용체 군에 속하면서 Wnt 신호 전달계의 대상 유전자로 세포의 성장 및 이동을 조절함으로써 종양의 발생과 진행을 억제한다. 연구자들은 한국인 위암에서 EphB2 단백의 발현 변화가 위암의 발생 및 진행에 관여하는지와 위암의 병리 지표들과의 연관성을 알아보고자 하였다. 대상 및 방법: 83예의 파라핀 포매된 위암조직에서 암세포들을 각각 3군데에서 펀치하여 새로운 파라핀 블록으로 옳겨 위암의 고집적 tissue microarray를 제작하였다. Tissue microarray 절편에서 EphB2 단백에 대한 항체로 면역조직화 학염색을 실시한 후 그 발현 양상을 병리 지표들인 조직학적 분류, 침습 정도, 림프절 전이 및 복막 파종과의 연관성을 조사하였다. 결과: EphB2 단백은 정상 위 점막 상피세포의 세포막과 세포질에서 발현되고 있었고 조사된 83예의 위암 중 30예 (36.1%)에서 발현이 소실되었다. 흥미롭게도 EphB2 단백의 발현 소실은 위암의 림프절 전이와 통계적으로 연관성이 있었으나 조직학적 분류, 침습 정도 및 복막 파종과는 연관성이 없었다. 결론: 이러한 소견들은 EphB2 수용체 단백의 발현 소실이 위암의 발생 및 진행에 있어 중요한 과정 중의 하나임을 의미한다.

• 한국HCI학회:학술대회논문집
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• 한국HCI학회 2009년도 학술대회
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• pp.1301-1308
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• 2009

In this paper, we conducted cross-cultural studies on digital images, which is an important element of the user interface. We brought in the schema theory to explain the cross-cultural difference in expressing and perceiving digital images. Participant-ethnography, in-depth interview, and card sorting were conducted to explore how expression and perception of image are influenced by schemas. Our results of qualitative studies indicate that there are differences in schemas between cultures depending on the topic of expression and perception. With these results, we suggest globalization and localization strategies of website.

• International Journal of Contents
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• 제8권4호
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• pp.78-87
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• 2012

In this paper, we conducted cross-cultural studies on digital images, which is an important element of the user interface. We brought in the schema theory to explain the cross-cultural difference in expressing and perceiving digital images. Participant-ethnography, in-depth interview, and card sorting were conducted to explore how expression and perception of images are influenced by schemas. Our results of qualitative studies indicate that there are differences in schemas between cultures depending on the topic of expression and perception. With these results, we suggest globalization and localization strategies for websites.

• 한국군사과학기술학회지
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• 제14권4호
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• pp.710-718
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• 2011

Edema factor(EF) is a portion of anthrax toxin which produces edema when combined with protective antigen. This paper describes about technique for cloning, expression, purification and activity test of EF. Using the E. coli expression system, we could make recombinant EF protein although it's origin is Bacillus anthracis. And also we could culture massively and purify highly pure protein. Finally we confirm a enzyme activity of purified EF to increase intracellular cAMP level. Through establishing this technique, it can be possible to research about EF in depth and apply to expression and purification of many other protein in biology.

• Asian-Australasian Journal of Animal Sciences
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• 제30권2호
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• pp.275-283
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• 2017

Objective: An experiment was conducted to investigate the environment of the deep litter system and provided theoretical basis for production. Methods: The bedding samples were obtained from a pig breeding farm and series measurements associated with gases concentrations and the bacterial diversity as well as the quantity of Escherichia coli, Lactobacilli, Methanogens were performed in this paper. Results: The concentrations of $CO_2$, $CH_4$, and $NH_3$ in the deep litter system increased with the increasing of depth while the $N_2O$ concentrations increased fiercely from the 0 cm to the -10 cm depth but then decreased beneath the -10 cm depth. Meanwhile, the Shannon index, the dominance index as well as the evenness index at the -20 cm layer was significantly different from the other layers (p<0.05). On the other hand, the quantity of Escherichia coli reached the highest value at the surface beddings and there was a significant drop at the -20 cm layer with the increasing depth. The Lactobacilli numbers increased with the depth from 0 cm to -15 cm and then decreased significantly under the -20 cm depth. The expression of Methanogens reached its largest value at the depth of -35 cm. Conclusion: The upper layers (0 cm to -5 cm) of this system were aerobic, the middle layers (-10 cm to -20 cm) were micro-aerobic, while that the bottom layers (below -20 cm depth) were anaerobic. In addition, from a standpoint of increasing the nitrification pathway and inhibiting the denitrification pathway, it should be advised that the deep litter system should be kept aerobic.

• Asian Pacific Journal of Cancer Prevention
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• 제16권3호
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• pp.1073-1076
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• 2015

Background: To explore the relationship between CXCR4, CD133 co-expression and clinicopathological features as well as prognosis of patients with phase II~III colon cancer. Materials and Methods: Forty-nine paraffin-embedded samples of tumor tissue and epithelial tissue adjacent to cancer were collected from patients with colon cancer undergoing radical surgery in Baotou Cancer Hospital from January, 2010 to June, 2011. CXCR4 and CD133 expression was detected using immunohistochemistry and its relationship with clinicopathological features and the 3-year survival rate was analyzed. Results: In the tumor tissue and colonic epithelial tissue adjacent to cancer, the positive expression rates of CXCR4 were respectively 61.2% (30/49) and 8.16% (4/49), while those of CD133 being 36.7% (18/49) and 6.12% (3/49). CXCR4 and CD133 expression in tumor tissue was not related to patient age, gender, primary focal sites, tumor size, TNM staging, histological type, tumor infiltration depth and presence or absence of lymphatic metastasis, but CXCR4 and CD133 co-expression was associated with TNM staging and lymphatic metastasis. The 3-year survival rate of patients with CXCR4 and CD133 co-expression was 27.3% (3/11), and that of the remainderwas 76.3% (29/38), the difference being significant ($X^2=7.0206$, p=0.0081). Conclusions: CXCR4 and CD133 co-expression may be a risk factor for poor prognosis of patients with stage II~III colon cancer.