• Korean Journal of Acupuncture
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• v.38 no.2
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• pp.75-99
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• 2021

Objectives : The purpose of this study is to analyze animal behavioral changes and related neurobiological mechanisms in recent studies using animal models with pain and depression. Methods : We conducted database search in Pubmed, NDSL, and EMBASE up to January 2021. Included studies were classified as depression-like behavior observed in pain model, pain-like behavior observed in depression model, and pain and depression comorbidity model. The results of pain- and depression-like behaviors, the changes of neurobiological mechanisms, and the treatment methods such as drugs, natural substance-derived chemicals, or acupuncture were analyzed. Results : We included 124 studies (81 studies in depression-like behavior observed in pain model, 19 studies in pain-like behavior observed in depression model, and 24 studies in pain and depression comorbidity model). Pain and depression comorbidity animal models were induced using various methods by drugs or surgery. Von frey test, a method for evaluating mechanical allodynia was the most commonly used for measuring pain-like behavior and the forced swimming test was the most commonly used for measuring depression-likes behavior. The changes of neurobiological factors, such as decrease of 5-hydroxytryptamine and increase of oxidative stress and pro-inflammation cytokines were generally changed in the frontal cortex, hippocampus, thalamus, and spinal cord in all types of models. For treating pain and depression-like behaviors, various types of drugs such as antidepressant, tranquilizer, analgesic, and natural substance-derived chemicals were used. Acupuncture treatment was used in 4 studies. Conclusions : In the future, more diverse studies on the combined model of pain and depression need to be conducted. In addition, it is necessary to establish a mechanistic basis for the development of various treatments by identifying the common mechanisms of pain and depression.

• Korean Journal of Biological Psychiatry
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• v.12 no.2
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• pp.89-97
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• 2005

Depression is a frequently developed psychiatric symptom after stroke. Poststroke depression(PSD) causes not only psychological distress related to depression but also other disturbances in many areas such as cognitive function, activities of daily living and quality of life. Therefore, a comprehensive understanding of accurate detection and appropriate treatment of depression is mandatory in patients with stroke. This review focused on the current knowledge of PSD.

• Journal of Korean Academy of Nursing
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• v.31 no.3
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• pp.391-400
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• 2001

Purpose: The purpose of this study was to examine depression in order to identify and improve health care policies promoting health among Korean women. Method: There were 329 participants, all older than 18 years old, and staying in Kyungki-Do, city. The data was collected from July to September 1999. The instrument used for this study was the CES-D (Center for Epidemiologic Studies Depression Scale) to evaluate depression. The collected data was analyzed with frequency, percentage, t-test, ANOVA, $\chi$2-test and Multiple logistic Analysis. Result: The result of this study are as follows: 1. Among the participants, 90.6% had normal to mild depression and 9.4% had severe depression. 2. For general characteristics, there were significant difference in the degree of depression according to age(P=0.0001), and marital status(P=0.0001). As for health related characteristics, the depression scores were affected by health perception(P= 0.0001), menopause(P=0.0005), stress (P= 0.0001) and sexual activity(P=0.0001). 3. There was a significant relationship between marital status and stress. Conclusion: This study suggests that a replicate study is needed. The results are also is useful in developing various nursing intervention programs.

• Journal of the Korean Society of Physical Medicine
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• v.3 no.4
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• pp.285-292
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• 2008

Purpose : To estimate the prevalence of and identity the associates of cognitive function and depression among people over 70 years of age, and to examine the relationship between cognitive impairment and depression, Methods : The elderly in Pusan area were studied on the Korea version Mini Mental Scale Examination instrument(MMSE-K), Short form of Geriatic Depression Scale(SGDS). Results : The prevalence of cognitive impairment($MMSE{\leq}24$) was 64.4% and that of depression($GDS{\geq}8$) was 40.7% Lower education, no religion and no work experience were associated with cognitive impairment. Depression in demented group was 68.2%, in suspect dementia group was 43.7% and in non-demented group was 9.5%. Conclusion : The prevalence of cognitive impairment and depression in elderly was high and depression was in association with cognitive impairment.

• Journal of the Korean Society of Physical Medicine
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• v.5 no.4
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• pp.623-632
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• 2010

Purpose : The purpose of this study was to identify the effect of recovery of disability on post-stroke depression in stroke patients. Methods : Fifty patients with stroke were participated in this study. The stroke impact scale(SIS) was used to assess the recovery of disability according to stroke and short form of geriatric depression scale(SGDS) was used to assess the poststroke depression(PSD). Results : The suspicious for depression were exhibited in 38%(n=19) and patients with depression were 58% (n=26) of 50 patients with stroke. In correlation between recovery of disability and depression, emotion and recovery of stroke negatively correlated with depression(p<.05). Conclusion : These results demonstrates that patients with stroke need to manage and treat emotion for the prevention and management of PSD.

• Korean Journal of Adult Nursing
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• v.23 no.4
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• pp.397-402
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• 2011

Purpose: This study was designed to explore the relationship of depression with stress, anxiety and mindfulness in nursing students in 2010. Methods: A cross-sectional design was used and data was collected through structured questionnaires. Depression, stress, anxiety, and mindfulness were measured by using the Depression, Anxiety and Stress Scale (DASS) and the Mindfulness Attention Awareness Scale (MAAS). The data were analyzed using t-test, one-way ANOVA, Pearson correlation coefficient, and stepwise multiple regression. Results: A total of 131 nursing students participated in this study. Depression was positively associated with stress (r=.81, p<.001) and anxiety (r=.76, p<.001), and negatively associated with mindfulness (r=-.73, p<.001). Multiple regression analyses showed that in different type of residence, anxiety and mindfulness were statistically significant predictors of depression with explanatory power of 67%. Conclusion: When nurse instructors manage depression among nursing students, the strategies need to address stress, anxiety, and mindfulness. This study may help nursing students to better manage their depression.

• The Journal of Korean Obstetrics and Gynecology
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• v.28 no.2
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• pp.76-90
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• 2015

Objectives : This study were invesitigated papers published in international journals to assess the effect of Korean Medicine treatments for menopausal depression. Through this review, we aimed to research more effective ways of menopausal depression treatment. Methods : The database of this review was created through searching PubMed from Jan, 2005 to Feb, 2015 : using terms of ‘menopausal depression’ and ‘post menopausal depression’ with ‘acupuncture’, ‘alternative medicine’, ‘CAM’ and ‘herbal medicine’. Results : 119 studies were analyzed but some of them were excluded due to lack of relevance or noncomformity of subjects. Finally, 16 studies were included in this review. Conclusions : In 16 studies, the acupuncture and herb decoction had significant interventions to improve menopausal depression. Therefore Acupuncture and herbal medicine may be effective treatment method of menopausal depression.

• Korean Journal of Childcare and Education
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• v.14 no.5
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• pp.101-115
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• 2018

Objective: The goals of this research were (1)to examine the relationship among parental conflict, mothers' depression and preschoolers' sleep problems, and (2) to examine the mediating effects of mothers' depression between marital conflict and preschoolers' sleep problems. Methods: The participants were 1,639 mothers with preschoolers taken from the 5th year Korean Children Panel. Date were analyzed using descriptive statistics, partial correlation analysis, and multiple regression analysis. Results: The results were as follows: First, preschoolers' sleep problems were positively related to marital conflicts. Second, preschoolers' sleep problems were positively related to mothers' depression. Third, marital conflict was positively related to mothers' depression. Lastly, mothers' depression fully mediated the relationship between marital conflict and preschoolers' sleep problems. That is, marital conflict had an effect on preschoolers' sleep problem, only through mothers' depression. Conclusion/Implications: Based on the results, intervention programs should be developed to prevent preschoolers' sleep problems such as marital relationship improvement programs and mothers' depression improvement programs.

• Korean Journal of Acupuncture
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• v.33 no.2
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• pp.84-88
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• 2016

Objectives : To assess and compare the effectiveness of acupuncture treatment of depression in epilepsy children and adolescent's parents. Methods : 20 cases of depression in epilepsy children and adolescent's parents were investigated in Southern TCM Centre, Southern University College, Malaysia. Subjects were randomly divided into two groups; Acupuncture treatment group and Herbal medication treatment group. Family relationships questionnaires and Hamilton Depression Rating Scale were used before, after 4 weeks and 8 weeks treatments in order to investigate the effectiveness of treatment. Results : After 4 weeks Acupuncture treatment group showed significant reduction in the Hamilton Depression Rating Scale. On the other hand, after 8 weeks both groups showed significant reduction in Hamilton Depression Rating Scale. Conclusions : The result suggests that the effectiveness of Acupuncture treatment is comparable with treat of Herbal medication treatment to reduce parent's Hamilton Depression Rating Scale.

• Journal of Yeungnam Medical Science
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• v.35 no.1
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• pp.27-35
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• 2018

Diabetes and depression are serious chronic conditions. As a result of their increasing prevalence, diabetes and depression, together with population growth and aging, are public health issues. The rate of depression in adults with either type 1 diabetes or type 2 diabetes is high relative to the general population. The coexistence of diabetes and depression has attracted much interest. Although it is unclear whether diabetes and depression are causally linked, most studies have shown that the association between diabetes and depression might be bidirectional. Currently, emotional well-being is becoming an increasingly important aspect of diabetes care and self-management. Psychiatric disorders and diabetic distress among people with diabetes may increase the risk of diabetes complication and mortality. Thus, assessment and appropriate management of depression in people with diabetes should be considered to achieve psychological well-being and optimize medical outcomes.