• 제목/요약/키워드: Dependence Assessment

검색결과 127건 처리시간 0.031초

Cigarette Smoking and Pancreatic Cancer Risk: A Revisit with an Assessment of the Nicotine Dependence Phenotype

  • Nakao, Makoto;Hosono, Satoyo;Ito, Hidemi;Oze, Isao;Watanabe, Miki;Mizuno, Nobumasa;Yatabe, Yasushi;Yamao, Kenji;Niimi, Akio;Tajima, Kazuo;Tanaka, Hideo;Matsuo, Keitaro
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권7호
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    • pp.4409-4413
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    • 2013
  • Background: Cigarette smoking is a well-established risk factor of pancreatic cancer (PC). Although an association between nicotine dependence phenotype, namely time to first cigarette (TTFC) after waking, and the risk of several smoking-related cancers has been reported, an association between TTFC and PC risk has not been reported. We assessed the impact of smoking behavior, particularly TTFC, on PC risk in a Japanese population. Materials and Methods: We conducted a case-control study using 341 PC and 1,705 non-cancer patients who visited Aichi Cancer Center in Nagoya, Japan. Exposure to risk factors, including smoking behavior, was assessed from the results of a self-administered questionnaire. The impact of smoking on PC risk was assessed with multivariate logistic regression analysis adjusted for potential confounders to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Results: Cigarettes per day (CPD) and/or smoking duration were significantly associated with PC risk, consistent with previous studies. For TTFC and PC risk, we found only a suggestive association: compared with a TTFC of more than 60 minutes, ORs were 1.15 (95%CI, 0.65-2.04) for a TTFC of 30-60 minutes and 1.35 (95%CI, 0.85-2.15) for that of 0-30 minutes (p trend=0.139). After adjustment for CPD or smoking duration, no association was observed between TTFC and PC. Conclusions: In this study, we found no statistically significant association between TTFC and PC risk. Further studies concerning TTFC and PC risk are warranted.

한중 FTA체결에 따른 정부의 MRA 활용 방안에 관한 연구 -TBT 및 적합성평가를 중심으로- (A Study on the utilization plan of Mutual Recognition Agreement for Korea-China FTA: Focused on TBT and Conformity Assessment)

  • 전병호;강병구
    • 통상정보연구
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    • 제17권3호
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    • pp.177-201
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    • 2015
  • 한국은 경제성장에 있어 무역 의존도가 매우 높은 나라로, 특히 중국에 대한 의존도가 높다. 비관세 장벽 중 무역상 기술 장벽(TBT)의 중요도가 크게 증가하고 있는데, 한국과 중국 양국간 교역에서 기술장벽이 미치는 영향이 크기 때문에 무역상 기술장벽의 제거는 FTA 체결에 있어서 한국 정부가 관심을 가지고 있는 쟁점 사항 중 하나이다. 상호인정협정(MRA)이 그러한 기술 장벽을 해소할 수 있는 효과적인 수단으로 주목받고 있는데, 기존의 연구들은 MRA가 수입 장벽을 완화시켜 주고 국제 시장에서 많은 기업들이 직면하고 있는 문제점들을 해결해 줄 수 있을 것이라 밝히고 있다. 이에 본 연구에서는 2015년 가서명된 한중 FTA 체결에 있어서 MRA의 활용 방안을 모색해 보고자 하였는데, 교역량과 양국간 규제의 차이를 고려한 적합한 MRA 활용 방안을 제시하였다. MRA 관련한 기존의 연구들은 MRA의 필요성과 그 효과에 대한 분석에 그치고 있는데 반해, 본 연구는 한국과의 교역량이 큰 중국이라는 특정 국가를 대상으로 구체적인 MRA 활용 방안을 모색하였다는데 그 의의가 있다.

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병원입원환자의 서비스. 영양관리. 식단 만족 요인집단에 따른 만족도 분석 (The Assessment of Patient Satisfaction in Accordance with Hospital Patients Food Service Cluster Groups)

  • 장은재;김혜진;홍완수
    • 대한지역사회영양학회지
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    • 제5권1호
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    • pp.83-91
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    • 2000
  • The aims of this study are to evaluate the quality of hospital food services and the evaluate the quality in selected hospitals trough the use of the questionnaires. A survey of 30 hospital food and nutrition service department was undertaken and detailed information was collected from each, including, surveys of 1, 016 patient. Statistical data analysis was completed using the SAS/win 6.11 package for descriptive analysis, t-test X$^2$-test ANOVA principal component analysis , and cluster analysis and cluster analysis. In the case of patient satisfaction with hospital food and food services, overall satisfaction scores of male and female were 3.54 and 3.45 showing higher levels than the average score(3.00) The aspect of the food and food service which received the lowest ratings by patients was 'meal rounding while dining'. After conduction of factor analysis of variables affecting the patients meal satisfaction 3 groups including the 'menu satisfaction factor', 'service satisfaction factor ' and 'nutrition management satisfaction factor ' were selected. 3 clusters were categorized by the 'service cluster' 'nutrition management cluster', 'men cluster', and 'menu nutrition service cluster' after conducting a cluster analysis with influencing variables affecting patients meal satisfaction. The overview results of patient satisfaction by cluster were : in the case of the service group, such factors as taste, portion size, dealing with complaints while dining meal rounding while dining should be managed with caution In case of the nutrition management group, such factors as taste, portion size, temperature of the food intake, and dependence on hospital food should be managed with care, In the case of the menu groups, such factors as punctuality of meal times, contaminated substances in meals and serving mistakes, cleanliness of dishes, kindness of the server meal rounding while dining should by particularly managed with importance.

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담수역 징거미 새우(Macrobrachium koreana)의 음향 반사 강도 특성 (Acoustic target strength measurements on immobile riverine shrimp, oriental river prawn(Macrobrachium koreana), in freshwater)

  • 황보규;신현옥;조성호;이대재;강돈혁
    • 수산해양기술연구
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    • 제44권1호
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    • pp.37-45
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    • 2008
  • Assessment and management of fisheries abundance in fresh water like a river or a lake is very important to maintain fisheries itself as well as tourist industry even if their scale is not much large. The species for catch in fresh water are mainly a mandarin fish, a carp, an eel, and others. Because oriental river prawn is a main prey of these species and the change in its abundance is directly related to their abundance change in fresh water, information on the abundance and distribution of the species are necessary. Hydroacoustic survey is known to one of the efficient method among several methodology. Information on acoustic target strength is key parameter to estimate abundance for acoustic survey. In this study, measurements on oriental river prawn, Macrobrachium koreana, were conducted for two high frequencies(200kHz and 420kHz) with tilt angle using automatic rotating system. The results of acoustic target strength obtained from the experiment were compared with those of acoustic scattering model, Distorted Wave Born Approximation(DWBA) model. For 200kHz, the result of acoustic target strength experiments was expressed in terms of the averaged target strength dependence on the body langth(BL, cm) as a following relationship; < $TS_{200kHz}$ > = 45.9log(BL) - 107.4. These results provide basic information for studying acoustic target strength and conducting acoustic survey of oriental river prawn.

Exploring Concurrent Validity and Item Level Analysis for Two Korean Versions of Health-Related Quality of Life Instrument: EQ-5D vs. WHOQOL-BREF

  • Choi, Bongsam
    • 한국전문물리치료학회지
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    • 제27권4호
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    • pp.233-240
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    • 2020
  • Background: Cross-culturally adapted questionnaires may not be comparable to their original version. Objects: To examine concurrent validity of two health-related quality of life (HRQOL) instruments for the Korean versions of EuroQOL-5 Dimension (EQ-5D) and the abbreviated version of the World Health Organization Quality of Life (WHOQOL-BREF) instrument. Methods: A total of 139 cancer survivors from two rehabilitation institutes was recruited. All participants were registered for palliative rehabilitation care. Both instruments were concurrently administered by health care providers following the second bout of the rehabilitation cares. Rasch partial credit model and Spearman's correlation analysis were used to investigate: 1) dimensionality, 2) hierarchical item difficulty, and 3) concurrent validity using correlations between two instruments. Results: For the WHOQOL-BREF, all items except negative feeling, pain, dependence of medical aid, were found to be acceptable, while all items of EQ-5D were acceptable. There was an evidence of negative correlations between EQ-5D and 4 domains of WHOQOL-BREF. Two correlations were strong (EQ-5D vs. physical health domain, ρ = -0.610, 95% CI = -0.716 to -0.475) and moderate (EQ-5D vs. psychosocial domain, ρ = -0.402, 95% CI = -0.546 to -0.236). Other two correlations were weak (EQ-5D vs. social relationship and environmental domains, ρ = -0.242, 95% CI = -0.401 to -0.075 and ρ = -0.364, 95% CI = -0.514 to -0.207, respectively). Item difficulty calibrations of the two measurements were ranged from -0.84 to 0.86 for the EQ-5D and -1.07 to 1.06 for the WHOQOL-BREF. Conclusion: The study provides some supports for the concurrent validity of the two Korean versions of HRQOL instrument, with evidences of weak to strong correlations between the EQ-5D and four domains of the WHOQOL-BREF applied to various cancer survivors. Additionally, the cancer survivors appeared to have more of a tendency to view the EQ-5D items as being slightly more challenging than the WHOQOL-BREF items.

Temporal Epidemiological Assessment of Colorectal Cancer Incidence and Mortality in East Kazakhstan, 2004-2013

  • Zhabagin, Kuantkan;Igissinov, Nurbek;Manambayeva, Zukhra;Adylkhanov, Tasbolat;Sandybayev, Marat;Nurgazin, Murat;Massadykov, Adilzhan;Tanatarov, Sayat;Aldyngurov, Daniyar;Urazalina, Nailya;Abiltayeva, Aizhan;Baissalbayeva, Ainoor;Zhabagina, Almagul;Sabitova, Dinara;Zhumykbayeva, Nurgul;Kenbayeva, Dinara;Rakhimbekov, Alexander
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권15호
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    • pp.6413-6416
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    • 2015
  • Colorectal cancer incidence and mortality in Kazakhstan are relatively high but exact statistics have hitherto been lacking and trends over time are unclear. The present study was therefore undertaken to retrospectively assess data for East Kazakhstan, accessed from the central registration office, for the period 2004-2013. Approximate age standardized data for incidence and mortality were generated and compared across age groups, gender and year. It was determined that during the studied period 3,417 new cases of colorectal cancer were registered and 2,259 died of this pathology. Average cancer cancer incidence and mortality over the ten years were $24.1/10^5$ and $15.9/10^5$ respectively, and the overall ratio of mortality/incidence (M/I) was 0.69:1 (range 0.58-0.73). Both incidence and mortality tended to remain constant in both males and females. The male to female ratios also did not significantly vary over time but a trend for improvement of the mortality to incidence ratio was observed, especially for rectum. Whether this might be related to screening remains unclear. These preliminary data indicate that whereas colorectal cancer continues to be important, change in environmental factors are not having a great impact on incidence in East Kazakhstan.

Spatial and Temporal Epidemiological Assessment of Breast Cancer Incidence and Mortality in Kazakhstan, 1999-2013

  • Beysebayev, Eldar;Bilyalova, Zarina;Kozhakeeva, Lyazzat;Baissalbayeva, Ainur;Abiltayeva, Aizhan
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권15호
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    • pp.6795-6798
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    • 2015
  • Breast cancer incidence and mortality in Kazakhstan are considered to be increasing but exact statistics have hitherto been lacking. The present study was therefore undertaken to retrospectively assess data for the whole country, accessed from the central registration office, for the period 1999-2013. Age standardized data for incidence and mortality were generated and compared across age groups. It was determined that during the studied period 45,891 new cases of breast cancer were registered and 20,122 women died of this pathology. Average breast cancer incidence and mortality were $37.9{\pm}1.10/10^5$ and $16.7{\pm}0.20/10^5$ respectively, and the overall ratio of mortality/incidence (M/I) was 0.44. Incidence tended to increase (T = + 2.3%), and mortality to decrease (T of =-0.3%). Peaks of incidence and mortality were noted in those aged 60-74 years and 75-84, respectively. Particularly high incidences were established in large cities of Kazakhstan, Astana ($46.8{\pm}1.80/10^5$) and Almaty ($49.7{\pm}1.30/10^5$), and high mortality was observed in the Pavlodar region ($17.9{\pm}0.60/10^5$) and Almaty city ($20.1{\pm}0.40/10^5$). Considerable variation in the mortality/incidence ratio was noted, suggesting the need for more stress on access to screening and clinical care in some regions of the country.

초음파 특성을 이용한 경년열화 평가 (Aging Degradation Assessment of Materials by Ultrasonic Characterization)

  • 박은수;박익근;김덕희;안형근
    • 비파괴검사학회지
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    • 제22권2호
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    • pp.149-154
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    • 2002
  • 실제 사용 온도 보다 높은 $630^{\circ}C$에서 열처리 시간을 변수로 하여 최대 1000 시간 동안 등온 열처리를 통해 2.25Cr-1Mo 강의 경년열화재를 제작하고 열화에 따른 미세조직과 기계적 특성 변화에 대한 초음파 비파괴평가 법으로 표면 특성평가에 우수한 표면 SH파를 적용하였다. 열화에 따른 초음파의 감쇠와 전파시간 및 웨이블렛을 이용한 음속과 감쇠계수의 주파수 의존성평가를 수행한 결과 열화가 진행됨에 따라서 탄화물은 점차 조대화되고 경도는 감소하였다. 감쇠계수는 열화시간이 증가함에 따라서 증가하였고 전파시간 역시 열화의 초기단계에 급격히 증가했다. 초음파의 감쇠와 경도와는 좋은 상관관계를 나타내어 감쇠계수는 경년열화 평가에 중요한 파라미터임을 알 수 있었다.

에너지기술 R&D 프로그램 선정을 위한 퍼지 다기준의사결정 프레임워크 수립 (Establishment of a Fuzzy Multi-criteria Decision Making Method Framework for Selecting R&D Programs of Energy Technologies)

  • 이성곤;;김종욱
    • 한국수소및신에너지학회논문집
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    • 제20권1호
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    • pp.22-30
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    • 2009
  • Energy environment has been changing rapidly such as the fluctuation of oil prices and the effect on UNFCCC. Oil price change affects Korea's economy heavily due to her poor natural resources and large dependence of consumed energy resources. Korea takes the 4th place of importing the crude oil and 9th place in $CO_2$ emissions with the 1st place of $CO_2$ emissions increasing rate. Considering the current statue of Korea including oil price change and UNFCCC, Korea will be expected to be the Annex I nation due to Korean energy environments and the quantity of $CO_2$ emission. Energy technology development is a crucial key to cope with Korea's national energy security and environments. In this study, we establish the framework, which allocates the relative weights of assessment criteria and sub-criteria, for assessing and selecting R&D programs of energy technologies strategically. We integrated fuzzy theory and analytic hierarchy process (AHP) approach since the fuzzy AHP approach reflects the vagueness of human thoughts and perception effectively as making pairwise comparisons of criteria and alternatives. The fundamental data of this research results will support R&D planning phase for policy-makers and the production of well focused R&D outcomes.

Structural health monitoring of high-speed railway tracks using diffuse ultrasonic wave-based condition contrast: theory and validation

  • Wang, Kai;Cao, Wuxiong;Su, Zhongqing;Wang, Pengxiang;Zhang, Xiongjie;Chen, Lijun;Guan, Ruiqi;Lu, Ye
    • Smart Structures and Systems
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    • 제26권2호
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    • pp.227-239
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    • 2020
  • Despite proven effectiveness and accuracy in laboratories, the existing damage assessment based on guided ultrasonic waves (GUWs) or acoustic emission (AE) confronts challenges when extended to real-world structural health monitoring (SHM) for railway tracks. Central to the concerns are the extremely complex signal appearance due to highly dispersive and multimodal wave features, restriction on transducer installations, and severe contaminations of ambient noise. It remains a critical yet unsolved problem along with recent attempts to implement SHM in bourgeoning high-speed railway (HSR). By leveraging authors' continued endeavours, an SHM framework, based on actively generated diffuse ultrasonic waves (DUWs) and a benchmark-free condition contrast algorithm, has been developed and deployed via an all-in-one SHM system. Miniaturized lead zirconate titanate (PZT) wafers are utilized to generate and acquire DUWs in long-range railway tracks. Fatigue cracks in the tracks show unique contact behaviours under different conditions of external loads and further disturb DUW propagation. By contrast DUW propagation traits, fatigue cracks in railway tracks can be characterised quantitatively and the holistic health status of the tracks can be evaluated in a real-time manner. Compared with GUW- or AE-based methods, the DUW-driven inspection philosophy exhibits immunity to ambient noise and measurement uncertainty, less dependence on baseline signals, use of significantly reduced number of transducers, and high robustness in atrocious engineering conditions. Conformance tests are performed on HSR tracks, in which the evolution of fatigue damage is monitored continuously and quantitatively, demonstrating effectiveness, adaptability, reliability and robustness of DUW-driven SHM towards HSR applications.