• Title/Summary/Keyword: Dentinogenic ghost cell tumor (DGCT)

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Dentinogenic Ghost Cell Tumor: A Case Report and Review of Literature (상아질성 유령세포종양: 증례보고와 문헌고찰)

  • Kim, Soung Min;Choi, So Young;Lee, Jae Il;Huh, Kyung Hoe;Myoung, Hoon;Lee, Jong Ho
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.35 no.1
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    • pp.66-71
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    • 2013
  • Dentinogenic ghost cell tumor (DGCT) is a rare epithelial odontogenic neoplasm, representing 1.9% to 2.1% of all odontogenic tumors. It is the neoplastic counterpart of the calcifying odontogenic cyst (COC), and characteristic islands of odontogenic epithelical cells contain numerous ghost cells and dysplastic dentin, and also have many common histological features with ameloblastoma. The 2005 World Health Organization (WHO) Classification of Odontogenic Tumours re-named this entity as calcifying cystic odontogenic tumor (CCOT) and defined the clinico-pathological features of the ghost cell odontogenic tumours, CCOT, DGCT and ghost cell odontogenic carcinoma (GCOC). We report a rare case of central DGCT in the posterior maxilla of a 31-year-old female with literature review, for the emphasis of Oral and Maxillofacial surgeon's role.

Ghost cell odontogenic carcinoma: A case report

  • Panprasit, Wariya;Lappanakokiat, Napas;Kunmongkolwut, Sumana;Phattarataratip, Ekarat;Rochchanavibhata, Sunisa;Sinpitaksakul, Phonkit;Cholitgul, Wichitsak
    • Imaging Science in Dentistry
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    • v.51 no.2
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    • pp.203-208
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    • 2021
  • Ghost cell odontogenic carcinoma (GCOC) is a rare malignant neoplasm characterized by the presence of ghost cells. It is considered to originate from either a calcifying odontogenic cyst(COC) or a dentinogenic ghost cell tumor(DGCT). Its clinical and radiographic characteristics are non-specific, including slow growth, locally aggressive behavior, and eventual metastasis. This case report describes a 43-year-old Thai man with plain radiographs and cone-beam computed tomographic images revealing a unilocular radiolucency with non-corticated borders surrounding an impacted left canine associated with radiopaque foci around the cusp tip. Based on the microscopic findings, the lesion was diagnosed as GCOC. Partial maxillectomy of the right maxilla was performed, and radiotherapy was administered. An obturator was made to support masticatory functions Three years later, the lesion showed complete bone remodeling and no signs of recurrence, and long-term follow-up was done regularly.