• Journal of the Korean Operations Research and Management Science Society
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• v.12 no.1
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• pp.1-9
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• 1987

This paper considers (S -1, S) inventory models which have wide applications in reparable spare parts inventory systems and multi-echelon systems. We assume a discrete compounds Poisson demand and order size dependent delivery times ; when the replenishment order size is n, we assume the delivery time distribution is arbitrary with finite mean $b_{n}$ . On the basis of the fact the outstanding orders follow a certain queueing process, we introduce the results of Fakinos (1982). We develop the efficient recursive formulae to find the optimal $S^{*}$ under several performance measures as a function of the decision variable S. The results of this paper can be applied to the multi-echelon systems such as MEETRIC.C.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.35 no.4
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• pp.171-178
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• 2012

A possible heuristic to solve metropolitan area vehicle routing problems with variable vehicle speeds is suggested in this research. Delivery hours are classified into 4 different time zones to make variable vehicle speeds no change within the same time zone to make TDVRP simple to solve. The suggested heuristic consists of 2 stages such as initial solution development step and initial solution improvement step. A computer program using C++ is constructed to evaluate the suggested heuristic. Randomly generated vehicle routing problems are used for the experiments. This heuristic could be helpful to logistics companies by increasing delivery efficiencies since the 4 zone classification is taken from the observed traffic information offered by a local government.

• Journal of the Korea Safety Management & Science
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• v.24 no.1
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• pp.1-9
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• 2022

The growth of the online market is accelerating due to the development of technology and the pandemic era. The delivery service through the courier must be used to deliver the ordered goods to the customer through the online market. With the growth of the online market, the logistics market for delivery is also growing. The traffic and environmental problems are emerging as social issues. Urban logistics technology using underground space based on the urban railway developed to improve logistics efficiency in a metropolitan area and a new alternative to environmental problems. This study proposed a plan to secure system safety through safety analysis based on operational concept definition and scenario analysis by applying model-based perspective analysis to the system under development.

• The Journal of Information Systems
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• v.20 no.3
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• pp.161-186
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• 2011

To date, SCM research has mainly focused on the effects of controlled variables on SCM success and emphasized adoption strategies and critical success factors. Consequently, the effects of more uncontrolled variables such as partnership between SCM partners have been largely ignored. The purpose of this study, therefore, is to examine the effects of both controlled variables and uncontrolled variables on SCM performance through affecting RTE characteristics. The six factors examined in this study include Quality of information, partnership quality, Forecasting, Agility, Visibility, and SCM performance. In this study, SCM Performance was divided into three categories: Quality Performance, Cost Performance, Delivery Performance. All factors were examined from the perspective of part suppliers. The results of this study can be summarized as follows. First, SCM information quality positively affected SCM partnership quality, Forecasting, Agility, Visibility. Second, SCM partnership quality positively affected Forecasting, Agility. But, SCM partnership quality showed no significant effect on Visibility. Third, Forecasting had a significant impact on SCM performance. According to the detailed result of measuring SCM performance with Quality Performance, Cost Performance, Delivery Performance, although Forecasting affects Cost Performance, Delivery Performance directly, it does not affect Quality Performance directly. Fourth, Agility also had a significant impact on SCM performance. According to the detailed result of measuring SCM performance, Agility has significant impact on Quality Performance, Cost Performance, Delivery Performance. Fifth, Visibility, as expected, had a significant impact on SCM performance. According to the detailed result of measuring SCM performance, Visibility has significant impact on Quality Performance, Cost Performance, Delivery Performance.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.14 no.6
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• pp.125-132
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• 2015

This paper presents an event data delivery scheme for wireless sensor networks that use a GTS-based channel allocation scheme. Many sensor nodes can share a GTS channel for sending their normal data to the sink node. When there is an event at a node, the node makes a temporal route to the sink node and the nodes of the route can use the GTS channel in a privileged access. This scheme controls the backoff number effectively so the data delivery priority is given to the nodes of that route. Simulation results show that the event data delivery of the proposed scheme outperforms at the end-to-end transfer delay and jitter characteristics. The proposed scheme can effectively gather the event data using the guaranteed GTS channel of the route in proposed scheme.

• Applied Chemistry for Engineering
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• v.34 no.2
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• pp.121-125
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• 2023

Casein is a milk protein and one of the most important nutrients in milk. The composition is over 80% in cow's milk and about 20~45% in human's milk. Casein is highly biocompatible and biodegradable, so it has been studied for various biomedical materials applications as well as drug delivery systems. It is widely known that casein can be prepared as nanoparticles in the presence of the Ca²⁺ metal ion. Because casein is amphiphilic, hydrophobic drugs could be loaded inside to form a protein-based drug delivery system. In this study, we studied the optimum conditions for casein nanoparticle formation using natural metal ions present in the body, such as calcium, magnesium, zinc, and iron. It was confirmed that nanoparticles have a uniform size of around 150 nm and negative zeta potential values. In addition, it was demonstrated that casein nanoparticles have a cell viability of more than 80% and efficient intracellular uptake properties using confocal microscopy. From the results, it was also shown that the casein nanoparticles prepared using various metal ions have the potential to be biocompatible drug delivery carriers.

• Journal of Pharmaceutical Investigation
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• v.34 no.5
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• pp.351-362
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• 2004

The basic concept underlying gene therapy is that human diseases may be treated by the transfer of genetics material into specific cells of a patient in order to correct or supplement defective genes responsible for disease development. There are several systems that can be used to transfer foreign genetic material into the human body. Both viral and non-viral vectors are developed and evaluated for delivering therapeutic genes. Viral vectors are biological systems derived from naturally evolved viruses capable of transferring their genetics materials into host cells. However, the limitations associated with viral vectors, in terms of their safety, particularly immunogenecity, and their limited capacity of transgenic materials, have encouraged researchers to increasingly focus on non-viral vectors as an alternative to viral vectors. Although non-viral vectors are less efficient than viral ones, they have the advantages of safety, simplicity of preparation and high gene encapsulation capability. This article reviews the most recent studies highlighting the advantages and the limitation of gene delivery systems focused on non-viral systems compared to viral systems.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.4
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• pp.899-904
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• 2008

This paper deals with the analytical approach for the reliability assessment in radially operated distribution systems. The approach can estimate the expected reliability performance of distribution systems by a direct assessment of the configuration of the systems using the reliability indexes such as NDP(Non-Delivery Power) and NDE(Non-Delivery Energy). The indexes can consider the number and configuration of the load. but can not consider the characteristics of the load which is the one of the most important factor in the investment cost for the distribution systems. Therefore, this paper presents the new indexes considering the expected interruption cost for the load section and shows the effectiveness by simulating at the model systems.

• International Journal of Highway Engineering
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• v.20 no.2
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• pp.45-55
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• 2018

PURPOSES : This study aims to survey and analyze the status of the design and completion documents output delivery system in public construction projects in order to assess the problems of the Ministry of Land, Infrastructure and Transport (MOLIT)'s electronic delivery system, with a focus on roads and rivers, and to offer improvement measures. METHODS : This study first surveys and analyzes laws and existing study trends with regard to the design and completion documents output delivery system in public construction projects. It further analyzes the status of the output delivery system in public construction projects, including roads, rivers, expressways, water resources, and railroads. In addition, a comparative analysis of the current electronic delivery system of MOLIT and Korea Expressway Corporation in the road field is conducted, and the problems and improvement measures for MOLIT's electronic output delivery system are presented. This study seeks to analyze problems and prepare improvement measures with regard to road and river public construction projects, as ordered by MOLIT's five regional offices. RESULTS : This study sought to prepare the electronic output delivery system with regard to public construction projects and present the analysis of its major problems and improvement measures in four categories: "the preparation of electronic design documents output delivery system improvement measures including inspection and delivery," "preparation of guidelines, systems, etc., concerning electronic design documents," "preparation of improvement measures for the construction project management system and electronic design document support tools", and "linking of MOLIT's electronic output delivery system with relevant agencies and the expansion thereof to local governments." CONCLUSIONS : This study analyzed the current status and problems of the MOLIT's electronic output delivery system in the field of road and river construction projects, and presented corresponding improvement measures. This study is expected to address the problems of the MOLIT's electronic output delivery system, and to provide the foundation for the preparation of an efficient electronic output delivery system for design and completion documents. In addition, this study is expected to boost the quality and utilization of the electronic design documents output, and to exchange, share, and link construction information among relevant agencies so as to prepare the foundation for sharing construction information.

• Journal of The Korea Institute of Healthcare Architecture
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• v.28 no.3
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• pp.47-54
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• 2022

Purpose: This study presents the analysis on space usage of delivery departments in regional public hospitals. The results intention is to achieve improvement of the delivery environment for the mothers and newborns regarding exposure prevention and efficient infection control. The purpose of this study is to provide fundamental data for architectural plans and guidelines for the delivery department. Method: The investigation and analysis were based on research papers, legal systems, public medical statistical data, and the architectural floor plan drawing. For research, 20 regional public hospitals with an operating delivery room were excluded. Regarding data accessibility, 15 regional public hospitals were selected. Results: To overcome the increased vulnerability of the delivery department, the research results of basic data is provided for the establishment to address urgent needs and rapid response. Thus, the research results are as follows: Firstly, the delivery department needs to respond promptly according to the type of patients. For example, in a case of emergency surgery, a connected circulation plan with the related departments is needed. Secondly, for the environment of the delivery area, alleviating anxiety is imperative for pregnant patients and guardians, labor, childbirth, and recovery. Therefore, these needs must be addressed for treatment space and circulation. Lastly, the delivery department is classified into three areas for analysis: access area, treatment area, and support area. In most of the delivery departments of the 15 selected hospitals, there is no space for the access and support area except for the labor and delivery rooms in the treatment area. For the access area, a waiting area, changing room for pregnant women and guardians, and a storage space for contaminated linens are required for infection prevention, safety, and efficiency. For the treatment area, childbirth processes and circulation should have space reserved for labor, delivery, recovery, examination, and treatment. In preparation for an emergency during childbirth, emergency response measures and supporting space needs to be established. For the support area, circulation and rooms are to be designed for medical staff support, activity space, storage and transportation of equipment, and urgent medical treatment. Implications: Along with the low fertility rate and the decrease of medical institutions that operate delivery departments, for the purpose of establishing a public medical service system and a healthy medical environment for mothers and newborns, the researched information demonstrates basic data on space plan of delivery departments in regional public hospitals.