• Journal of information and communication convergence engineering
• /
• v.8 no.6
• /
• pp.623-629
• /
• 2010

A geographical routing protocol is typically utilized for a route selection of VANET. Even if it is conceptually well adapted into VANET, message delivery tends to be unreliable with frequent network partitions, which mainly come from the inherent characteristics such as high mobility and irregular traffic density. In this paper, we deal with a method to enable reliable message delivery with reflecting the traffic density on routing decision. By concatenating the message delivery cost of each of inbetween junction section, $1^{st}$ and $2^{nd}$ shortest paths are initially determined. When it is not possible to deliver the message on a junction on the 1st path, we utilize two novel ideas, that is, letting the message stay on the junction to find out a new relay node, and putting a replicated copy to reach via a detour path. By using the NS-2 network simulator, our method has been examined in terms of message delivery rate and delay. It shows that our method is much efficient than the other method in the low density environment, while it brings similar results in the high density environment.

• Design & Manufacturing
• /
• v.14 no.3
• /
• pp.57-62
• /
• 2020

In the drug delivery system industry, the technology with even split injection becomes important for maximizing efficiency and minimizing the side effects. In conventional drug delivery system, infection can occur due to pain and splashing. Also, various applications are impossible due to disposable use, and it is the reason to avoid to use this system because of the complexity of the driving method. Therefore, in this study, a painless drug delivery device is developed for non-pain with electrical insulation breakdown method. Finite elements analysis was used to evaluate the ejection characteristics of drugs according to the shape of the micro ejection nozzle. The effect of the number of holes in the micro nozzle, the length of the nozzle and the inner shape of the nozzle on the drug discharge characteristics were analyzed.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
• /
• 1997.10a
• /
• pp.225-231
• /
• 1997

This paper reports on the theoretical study of the delivery pressure ripples of a positive displacement vane pump which is widely used for automobile power steering. Pressure ripples occur due to the flow tipples which induced cam ring profiles and reverse flow from the delivery ports. In this paper, the mathematical model for analyzing the pressure ripples has been presented, and set of the differential equationshave been solved using the Runge-Kutta method. As the results of analysis, instant ideal flow ripples, internal pressure, delivery pressure ripples, and delivery flow ripples have been presented. Internal pressure was related to delivery pressure variations, and amplitude of pressure tipples was increased with rotational speed and delivery pressure.

• Journal of Pharmaceutical Investigation
• /
• v.16 no.3
• /
• pp.89-100
• /
• 1986

Although insulin has been available for the treatment of diabetes mellitus for more than half a centry, the deficiency of conventional insulin therapy for diabetic patients have, to this date, not been satisfactorily overcome by any method. The development of potential delivery systems for insulin is highly important to prevent excessive fluctuation of plasma glucose levels, which results in long term complications in the diabetic. There are three major approaches toward development of glucose responding insulin delivery systems: A bioengineering approach is to devise mechanical components capable of releasing insulin in amounts appropriate to varying blood-glucose requirements. A biological approach relies upon cultured, living pancreatic beta cells encapsulated to constitute an insulin delivery unit. A biochemical approach is to synthesize a stable and biologically active glycosylated insulin that is complementary to the binding sites of lectin. This paper will cover several specific areas, including pancreatic transplantation(total or isolated islet cells), artificial pancreases(bioengineering or biological approach), controlled delivery system, glucose sensitive membrane systems, and a self-regulating insulin delivery system.

• Journal of Institute of Convergence Technology
• /
• v.1 no.1
• /
• pp.48-51
• /
• 2011

Transdermal drug delivery device is a method of drug delivery through the skin. Skin has a very large area, so it is attractive route to drug delivery. When drug delivery through the skin, microneedle has a advantage that painless, constant drug deliver and penetration efficient; nevertheless the cost is expensive because fabrication process need a particular equipment and not suitable in mass production. This study shows microneedle fabrication process using convergence of general MEMS process and dicing process that can make 3-D sharp microneedle tip and this fabrication process suitable for mass production.

• Journal of Biomedical Engineering Research
• /
• v.43 no.2
• /
• pp.94-101
• /
• 2022

Recent advancement of micro/nano technology enables the development of diverse micro/nano particle-based delivery systems. Due to the multi-functionality and engineerability, particle-based delivery system are expected to be a promising method for delivery to the target cell. Since the particle-based delivery system should be delivered to the various kinds of target cell, including the cardiovascular system, cancer cell etc., it is frequently decorated with multiple kinds of targeting molecule(s) to induce specific interaction to the target cell. The surface decorated molecules interact with the cell surface expressed molecule(s) to specifically form a firm adhesion. Thus, in this study, the probability of adhesion is estimated to predict the possibility to form a firm adhesion for the multi-ligand decorated particle-based delivery system.

• International Journal of Advanced Culture Technology
• /
• v.11 no.2
• /
• pp.284-290
• /
• 2023

This study was a phenomenological study to examine the meaning and structure of the difficulty of delivery. Participants in this study conducted deep interviews with seven female 20 to 24. The interview data was conducted through the process of analysis and interpretation using the Giorgi method. As a result of study, 12 themes were derived and 4 categories. As a result of the analysis, young women's thoughts on observing delivery consisted of 'fear', 'powerlessness', 'disgust', and 'inevitable fate'. Based on the above meaning, the structure of young women's thoughts on delivery was found to be a point of view that it is regrettable that delivery compensates for all difficulties and pain with the joy of birth. Accordingly, it is proposed to develop and apply a program that can actually alleviate the anxiety, fear, and physical discomfort experienced by women in childbearing age through childbirth.

• Biotechnology and Bioprocess Engineering:BBE
• /
• v.6 no.4
• /
• pp.212-230
• /
• 2001

Recent advances in recombinant DNA technology have resulted in development of many new protein drugs. Due to the unique properties of protein druges, they have to be delivered by parenteral injection Although delivery of protein drugs by other routes, such as pulmonary and nasal routes, has shown some promises, to date most protein drugs are administered by par-enteral routs. For long-term delivery of protein drugs by parenteral administration, they have been formulated into biodegradable microspheres. A number of microencapsulation methods have been developed, and the currently used microencapsulation methods are reviewed here, The microen-capsulation methods have been divided based on the method used. They are: solvent evapora-tion/extraction; phase separation (coacervation);spray drying; ionotropic gelation/polyelectrolyte complexation; interfacial polyumerization and supercritical fluid precipitation. Each method is de-scribed fro its applications, advantages, and limitations.

• Proceedings of the IEEK Conference
• /
• 2002.07b
• /
• pp.830-833
• /
• 2002

To solve the internal security problem such as human error and bad faith, the automation of computer system management is significant. For this purpose, we focus attention in the automation of Mail Delivery Service. Today, requirement for reliable mail delivery system becomes larger and larger. However, existing systems are too strict about their configuration. Hence, we propose the method based on Reinforcement Learning (RL) to achieve proper MX record ordering. A measure on validity of the design of system, such as network topology number of servers and so on, is also obtained as side benefit. In order to verify the usability of the presented method, we did on a small model of mail delivery system. As a result, we show that RL is available for determination of the proper MX record ordering. Additionally, we suggest that it is also available for comparing validity of setting of MTA and the network design.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2002.10a
• /
• pp.101-104
• /
• 2002

Leading companies have embraced the new economy with new and innovative BTO models. Instead of conventional company-oriented manufacturing scheduling, customer-oriented scheduling method attracts more and more attention. To evaluate the delivery of customer order in advance, the real production capacity as well as procurement lead time should be taken into account. This paper describes a quasi-real-time order delivery estimation system using TOC(Theory of Constraints) based scheduling method.