• 제목/요약/키워드: Degradation evaluation

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Nondestructive Evaluation for Degraded 2.25Cr-1Mo Steel though Surface SH-wave (표면SH파를 이용한 2.25Cr-1Mo강의 열화.손상 평가)

  • Kim, Hyun-Mook;Park, Ik-Keun;Park, Un-Su;Ahn, Hyung-Keun;Kim, Chung-Soek
    • Proceedings of the KSME Conference
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    • 2000.11a
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    • pp.280-285
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    • 2000
  • It is very important to evaluate the surface or subsurface microstructure because of their influences on mechanical properties of materials. Surface SH-wave which is horizontally polarized shear wave traveling along near surface and subsurface layer is an attractive technique for material evaluation. The destructive method is widely used for the estimation of material degradation but it has a great difficulty in preparing specimens from in-service industrial facilities. In this study, nondestructive evaluation for degraded structural materials used at high temperature though surface SH-wave method is discussed. 2.25Cr-1Mo steel specimens which were prepared by the isothermal aging heat treatment at $650^{\circ}$ were evaluated though ultrasonic nondestructive evaluation techniques investigating the change of sound velocity, attenuation coefficient and amplitude spectra. In addition, it has verified experimentally the frequency-dependence of attenuation coefficient though wavelet analysis method.

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20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades

  • Zhu, Sirui;Liu, Xiaoli;Xue, Mei;Li, Yu;Cai, Danhong;Wang, Shijun;Zhang, Liang
    • Journal of Ginseng Research
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    • v.45 no.2
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    • pp.295-304
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    • 2021
  • Background: Acute promyelocytic leukemia (APL) is a hematopoietic malignancy driven by promyelocytic leukemia-retinoic acid receptor A (PML-RARA) fusion gene. The therapeutic drugs currently used to treat APL have adverse effects. 20(S)-ginsenoside Rh2 (GRh2) is an anticancer medicine with high effectiveness and low toxicity. However, the underlying anticancer mechanisms of GRh2-induced PML-RARA degradation and apoptosis in human APL cell line (NB4 cells) remain unclear. Methods: Apoptosis-related indicators and PML-RARA expression were determined to investigate the effect of GRh2 on NB4 cells. Z-VAD-FMK, LY294002, and C 87, as inhibitors of caspase, and the phosphatidylinositol 3-kinase (PI3K) and tumor necrosis factor-α (TNF-α) pathways were used to clarify the relationship between GRh2-induced apoptosis and PML-RARA degradation. Results: GRh2 dose- and time-dependently decreased NB4 cell viability. GRh2-induced apoptosis, cell cycle arrest, and caspase3, caspase8, and caspase9 activation in NB4 cells after a 12-hour treatment. GRh2-induced apoptosis in NB4 cells was accompanied by massive production of reactive oxygen species, mitochondrial damage and upregulated Bax/Bcl-2 expression. GRh2 also induced PML/PML-RARA degradation, PML nuclear bodies formation, and activation of the downstream p53 pathway in NB4 cells. Z-VAD-FMK inhibited caspase activation and significantly reversed GRh2-induced apoptosis and PML-RARA degradation. GRh2 also upregulated TNF-α expression and inhibited Akt phosphorylation. LY294002, an inhibitor of the PI3K pathway, enhanced the antitumor effects of GRh2, and C 87, an inhibitor of the TNF-α pathway, reversed NB4 cell viability, and GRh2-mediated apoptosis in a caspase-8-dependent manner. Conclusion: GRh2 induced caspase-dependent PML-RARA degradation and apoptosis in NB4 cells via the Akt/Bax/caspase9 and TNF-α/caspase8 pathways.

Evaluation of Natural Attenuation of Petroleum Hydrocarbons in a Shallow Sand Aquifer: a Modeling Study (자연저감 모델링 연구)

  • 이진용;이명재;이강근;이민효;윤정기
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2001.04a
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    • pp.128-131
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    • 2001
  • We evaluated natural attenuation of petroleum hydrocarbons in a shallow aquifer using a modeling study. The studied shallow aquifer was severely contaminated with petroleum hydrocarbons, especially toluene, ethylbenzene and xylenes (i.e, TEX). The exact spill history was not known. Therefor we used a contaminant level in May 1999 (the first sampling date of our integrated study) as an initial contaminant concentration. we calibrated required transport parameters using the contamination levels obtained from groundwater analyses in September of 1999. For fate and transport of the petroleum contaminants, five case 2 with sorption and degradation. case 3 with sorption and degradation (half decay constant compared with case 2), case 4 with degradation but no sorption, and case 5 with sorption but no degradation. For sorption and degradation, a linear sorption isotherm and first order irreversible decay was assumed, respectively and no additional contamination source to groundwater is also assumed.

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Analysis on Iris Image Degradation Factors (홍채 인식 성능에 영향을 미치는 화질 저하 요인 분석)

  • Yoon, So-Weon;Kim, Jai-Hie
    • Proceedings of the IEEK Conference
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    • 2008.06a
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    • pp.863-864
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    • 2008
  • To predict the iris matching performance and guarantee its reliability, image quality measure prior to matching is desired. An analysis on iris image degradation factors which deteriorate matching performance is a basic step for iris image quality measure. We considered five degradation factors-white-out, black-out, noise, blur, and occlusion by specular reflection-which happen generally during the iris image acquisition process. Experimental results show that noise and white-out degraded the EER most significantly, while others on EER were either insignificant or degradation images resulted in even better performance in some cases of blur. This means that degradation factors that affect the performance can be different from those based on human perception or image degradation evaluation.

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An Evaluation of Aging Degradation Damage for Cr-Mo-V Steel by Electrochemical Potentiokinetic Reactivation Test (재활성화 분극시험에 의한 Cr-Mo-V강의 시효열화 손상 평가)

  • Kwon, Il-Hyun;Na, Sung-Hun;Song, Gee-Wook;Yu, Hyo-Sun
    • Proceedings of the KSME Conference
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    • 2000.04a
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    • pp.49-54
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    • 2000
  • Cr-Mo-V steel is widely used as a material for the turbine structural component in fossil power plants. It is well known that this material shows the various material degradation phenomenons such as temper embrittlement, carbide coarsening. and softening etc. or ins to the severe operation conditions as high temperature and high pressure. These deteriorative factors cause tile change of mechanical properties as reduction of fracture toughness. Therefor it is necessary to evaluate tile extent of degradation damage for Cr-Mo-V steel in life assessment of turbine structural components. In this paper. the electrochemical potentiokinetic reactivation(EPR) test in $50wt%-Ca(NO_3)_2$ solution is performed to develop the newly technique for degradation damage evaluation of Cr-Mo-V steel. The results obtained from the EPR test are compared with those in small punch(SP) tests recommended by semi-nondestructive testing method using miniaturized specimen. The evaluation parameters used in EPR test are tile reactivation current density$(I_R)$ and charge$(Q_{RC})$ reactivation rate$(I_R/I_{Crit},\;Q_R/Q_{Crit})$. The results suggest that $I_R/I_{Crit}$ in these parameters shows a good correlation with SP test results.

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Lifetime Assessment for Oil-Paper Insulation using Thermal and Electrical Multiple Degradation

  • Kim, Jeongtae;Kim, Woobin;Park, Hung-Sok;Kang, Ji-Won
    • Journal of Electrical Engineering and Technology
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    • v.12 no.2
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    • pp.840-845
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    • 2017
  • In this paper, in order to investigate the lifetime of oil-paper insulation, specimens were artificially aged with thermal and electrical multiple stresses. Accelerated ageing factors and equivalent operating years for each aging temperatures were derived from results of tensile strengths for the aged paper specimens. Also, the evaluation for the multi-stress aged specimens were carried out through the measurement of impulse breakdown voltage at high temperature of $85^{\circ}C$. The lifetimes of the oil-paper insulations were calculated with the value of 66.7 for 1.0 mm thickness specimens and 69.7 for 1.25 mm thickness specimens throughout the analysis of impulse BD voltages using equivalent operating years, which means that dielectric strengths would not be severely decreased until the mechanical lifetime limit. Therefore, for the lifetime evaluation of the oil-paper insulation, thermal aging would be considered as a dominant factor whereas electrical degradation would be less effective.

Lifetime-Temperature Rise Model for the Evaluation of Degradation in Electric Connections/Contacts (전기적 접속/접촉부 열화 평가를 위한 수명 온도상승 모델)

  • Kim, Jeong-Tae;Kim, Nam-Jun
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.51 no.2
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    • pp.55-61
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    • 2002
  • In this paper, 'lifetime-temperature rise model' based on the 'lifetime-resistance model' is theoretically Proposed, in order to find out the evaluation method of degradation and the residual lifetime by use of infrared image camera for electric connections/contacts. Two assumptions have been builded up for the 'lifetime-temperature rise model': one is associated with the linear relationship between the temperature ism ΔK and contact resistance, and the other the functional relationship between the temperature of electric connections/contacts and the operating time presenting in the 'lifetime-resistance model'. To prove the proposed model, experiments have been performed for various electric connections/contacts. From the experimental results, measured values were quite similar to the calculated values, which proved the above-mentioned two assumptions. Therefore, by use of 'lifetime-temperature rise model', it is possible to estimate the trend of degradation and the residual lifetime for electric connections/contacts through the temperature measurements .

A Study on Irreversible Degradation through OCV Reduction and Recovery Behavior in the Electrochemical Degradation Process of PEMFC Polymer Membrane (PEMFC 고분자 막의 전기화학적 열화과정에서 OCV 감소 및 회복 거동을 통한 비가역적 열화 연구)

  • Yoo, Donggeun;Park, Kwon-Pil
    • Korean Chemical Engineering Research
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    • v.60 no.2
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    • pp.217-222
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    • 2022
  • It is very important to analyze the OCV change behavior during the open circuit potential holding (OCV holding) process, which accelerates the evaluation of the electrochemical durability of the PEMFC membrane. In this study, an empirical formula using the experimental data of three MEAs with different durability was created and compared. The durability evaluation time of the reinforced membrane MEA without radical scavenger inside the membrane was 383 h, and the durability evaluation time of the reinforced membrane MEA with radical scavenger inside the membrane was 1,000 and 1,650 h, respectively. The degradation of the membrane was divided into the reversible degradation that can be recovered by activation and the irreversible degradation that is not recovered. The irreversible degradation of the membrane was indicated by an increase in hydrogen permeability, and the change in hydrogen permeability was similar to the irreversible degradation constant c of all three MEAs. The initiation of irreversible deterioration without recovery is indicated by an increase in hydrogen permeability, and the OCV is not recovered due to an increase in hydrogen permeability, so the slope of the OCV recovery line (ORL) decreases, which can be confirmed by an increase in the constant c value of the empirical formula.

Development of a Numerical Model for Evaluation of Long-Term Mechanical Degradation of Shotcrete Lining in Tunnels (터널 숏크리트 라이닝의 장기 내구성 저하 평가를 위한 수치모델의 개발)

  • Shin Hyu-Soung;Lim Jong-Jin;Kim Dong-Gyu;Lee Gyu-Phil;Bae Gyu-Jin
    • 한국터널공학회:학술대회논문집
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    • 2005.04a
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    • pp.251-258
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    • 2005
  • In this study, a new concept for simulating a long-term mechanical degradation mechanism of shotcrete in tunnels has been proposed. In fact, it is known that the degradation takes place mainly by internal cracks and reduced stiffness, which results mainly from volume expansion of shotcrete and corrosion of cement materials, respectively. This degradation mechanism of shotcrete in tunnels appears similar to those of the most kinds of chemical reactions in tunnels. Therefore, the mechanical degradation induced by a kinds of chemical reaction was generalized and mathematically formulated in the framework of thermodynamics. The numerical model was implemented to a 3D finite element code, which can be used to simulate behaviour of shotcrete structures undergoing external forces as well as chemical degradation in time. A number of illustrative examples were given to show the feasibility of the model in tunnel designs with consideration of long-term degradation effect of shotcrete quantitatively for increase of long-term safety of tunnels.

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