• Journal of the Korean Chemical Society
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• v.45 no.3
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• pp.256-263
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• 2001

The STS contents, emphasized in the 6th curriculum, in the chemistry parts of general science textbooks were analyzed. The STS contents of textbooks showed average of 24.4%. The chapter in "modern science and technology" were included 45.5% in STS contents, 38.7% in "environment", 29.1% in energy, and 14.0% in "materials". When the STS contents were analyzed by STS topics of Piel, the results are as follows; 38.3% on environmental quality and utilization of natural source, 29.6% on effect of technological developments, 7.9% on energy, and 0.6% on human engineering. However, there were no topics on population, space research and national defense. When the STS contents were analyzed by student activities of SATIS, most of the activities were research and case study. There were few field activities of role play, problem solving and decision making, and research design.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.30 no.2
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• pp.119-125
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• 2017

Ablative material in a rocket nozzle is exposed to high temperature combustion gas, thus undergoes complicated thermal/chemical change in terms of chemical destruction of surface and thermal decomposition of inner material. Therefore, method for conjugate analysis of thermal response inside carbon/phenolic material including rocket nozzle flow, surface chemical reaction and thermal decomposition is developed in this research. CFD is used to simulate flow field inside nozzle and conduction in the ablative material. A change in material density and a heat absorption caused by the thermal decomposition is considered in solid energy equation. And algebraic equation under boundary layer assumption is used to deduce reaction rate on the surface and resulting destruction of the surface. In order to test the developed method, small rocket nozzle is solved numerically. Although the ablation of nozzle throat is deduced to be higher than the experiment, shape change and temperature distribution inside material is well predicted. Error in temperature with experimental results in rapid heating region is found to be within 100 K.

• Korean Security Journal
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• no.53
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• pp.283-303
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• 2017

This study which was started to identify the factors that change the security level of military organizations, analyzed the data collected from articles written by the active officers in the Defense Daily Journal hoping to improve the military security level by the qualitative research method called Grounded Theory, and establish causal relationship how organizational members respond to insider security threats. As a result of the analysis, the causal condition is 'the security threat of the insider', the contextual condition is 'the specificity of the military organization', the central phenomenon is 'the conflict of values as a soldier', the arbitrary condition is 'the security consciousness', Strategy is 'the responds to security threats', and the result was 'security level change'. The core categories can be presented as 'the degree of conflict of values on insider security threats' and two hypotheses have been derived. First, the members of the military organization strongly felt the conflict of values about security threat as the tendency to emphasize security was strong, and they helped to develop the security level of organization by responding strongly. Second, the stronger the tendency to focus on colleagues, respond weakly to security threats. And it undermines the security level of the organization. Finally, in order to improve the security level of the organization, it is necessary to establish a solid security consciousness and to make institutional development to support it.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.49 no.7
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• pp.39-47
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• 2012

The combination of the broadband property and the wide area coverage of satellite communications enables high speed transmission. Every user in the region under the satellite beam coverage can tranceiver and one can simultaneously communicate with multiple users. For these reasons, it is one of commendable telecommunication networks for information transfer. Since the satellite communications use open channels, it is likely to cause jamming with unwanted interference signals. In the thesis, APSK (Amplitude Phase Shift Keying) is employed, which is recommended for DVB-S2 due to high-speed transmission and excellent bandwidth efficiency. For obtaining reliable communication under the jamming environments, the communication satellite transponder rests on the polyphase filter bank structure, which enables switching among the subchannels and gain control on each subchannel, resulting in effectively eliminating jamming. Furthermore, the nulling scheme, one of the various anti-jamming approaches, is investigated, in which unwanted jamming signals are eliminated in the frequency domain after passing through the analysis part of the polyphase filter bank. The performance of the nulling scheme is evaluated for tone jamming and partial band jamming in terms of BER and EVM. The simulation results indicate that the nulling scheme improve the BER and EVM performance over the case without any anti-jamming approach.

• Korean Journal of Clinical Pharmacy
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• v.18 no.1
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• pp.38-44
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• 2008

Rebamipide, ($\pm$)-2-(4-chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl] propionic acid, is used for mucosal protection, healing of gastroduodenal ulcers, and treatment of gastritis. It works by enhancing mucosal defense, scavenging free radicals and temporarily activating genes encoding cyclooxygenase-2. The purpose of the present study was to evaluate the bioequivalence of two rebamipide tablets, $Mucosta^{(R)}$ (Korea Otsuca Pharmaceuticals Co., Ltd.) and Mustar (Korean Drug Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The release of rebamipide from the two rebamipide formulations in vitro was tested using KP VIII Apparatus II method with pH 6.8 dissolution medium. Twenty six healthy male subjects, $23.46{\pm}2.63$ years in age and $66.62{\pm}8.97\;kg$ in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After a single tablet containing 100 mg as rebamipide was orally administered, blood samples were taken at predetermined time intervals and the concentrations of rebamipide in serum were determined using HPLC with fluorescence detector. The dissolution profiles of two formulations were similar in the tested dissolution medium. The pharmacokinetic parameters such as $AUC_t$, $C_{max}$ and $T_{max}$ were calculated, and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, $Mucosta^{(R)}$ were -5.08, 3.52 and -9.71 % for $AUC_t$, $C_{max}$ and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g., log 0.84$\sim$log 1.07 and log 0.90$\sim$log 1.17 for $AUC_t$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Mustar tablet was bioequivalent to $Mucosta^{(R)}$ tablet.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.27 no.2
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• pp.198-207
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• 2016

Bistatric radar can perform detection and identification for stealth targets that are rarely detected by the conventional monostatic radar. However, high resolution range profile(HRRP) generated from the received signal in the bistatic radar cannot show exact range information of the target because the bistatic geometry lead to the distortions of the bistatic HRRP. In addition, electromagnetic scattering mechanisms of the target are varied depending on the bistatic geometry. Thus, efficient database construction is a crucial factor to achieve successful classification capability in bistatic target identification. In this paper, a database construction method based on realistic flight scenarios of a target, which provides a reliable identification performance for the monostatic radar, is applied to bistatic target identification. Then, the capability and efficiency of the method is analyzed. Simulation results show that reliable identification performance can be achieved using the database construction based on the flight scenarios when the target is a considerable distance away from the bistatic radar.

• International Journal of Oral Biology
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• v.36 no.3
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• pp.109-116
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• 2011

Periodontitis results from the activation of host immune and inflammatory defense responses to subgingival plaque bacteria, most of which are gram-negative rods with lipopoly-saccharides (LPSs) in their cell walls. LPSs have been known to induce proinflammatory responses and recently it was reported also that they induce the expression of microRNAs (miRNAs) in host cells. In our current study therefore, we aimed to examine and compare the miRNA expression patterns induced by the LPSs of major periodontopathogens in the human gingival epithelial cell line, Ca9-22. The cells were treated with 1 ${\mu}g$/ml of E. coli (Ec) LPS or 5 ${\mu}g$/ml of an LPS preparations from four periodontopathogens Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi), Aggregatibacter actinomycetemcomitans (Aa), and Fusobacterium nucleatum (Fn) for 24 h. After small RNA extraction from the treated cells, miRNA microarray analysis was carried out and characteristic expression profiles were observed. Fn LPS most actively induced miRNAs related to inflammation, followed by Aa LPS, Pi LPS, and Ec LPS. In contrast, Pg LPS only weakly activated miRNAs related to inflammation. Among the miRNAs induced by each LPS, miR-875-3p, miR-449b, and miR-520d-3p were found to be commonly up-regulated by all five LPS preparations, although at different levels. When we further compared the miRNA expression patterns induced by each LPS, Ec LPS and Pi LPS were the most similar although Fn LPS and Aa LPS also induced a similar miRNA expression pattern. In contrast, the miRNA profile induced by Pg LPS was quite distinctive compared with the other bacteria. In conclusion, miR-875-3p, miR-449b, and miR-520d-3p miRNAs are potential targets for the diagnosis and treatment of periodontal inflammation induced by subgingival plaque biofilms. Furthermore, the observations in our current study provide new insights into the inflammatory miRNA response to periodontitis.

• Convergence Security Journal
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• v.5 no.4
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• pp.41-48
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• 2005

Objective of this study is to design and implement security system based on intrusion tolerance technology for the improvement of dependability in defense system. In order to do so, I identify and extract core technologies through the research and analysis into characteristics, structures, main functions, and technologies of intrusion tolerance architecture. And I accomplish a design of security system through the redundant system based on these core technologies. To implement and verify intrusion tolerance system, I chose 'wargame system' as a subjected system, and accomplished 'Wargame Intrusion Tolerance System' and verified security required functions through a performance test. By applying showed security system into the development of application software based on intrusion tolerance, systematic and efficient system could be developed. Also applying 'WITDS' can solve the current security problems, and this will be basic model for design of security architecture in the federation system after.

• Journal of the Korea Society of Computer and Information
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• v.17 no.12
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• pp.61-69
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• 2012

This paper shows results of the precise time comparison technique based on GPS code transfer in order to determine the UTC(Universal Time Coordinated) and generate TAI(International Atomic Time). CGGTTS(CCTF Group on GNSS Time Transfer Standards) which is generated by GPS timing receivers is used as the international standard format. For geodetic receivers which provide RINEX formats as GPS time transfer results, ROB(Royal Observatory of Belgium) developed a conversion program, r2cggtts, and have distributed the program to timing laboratories participating in TAI link all over the world. Timing laboratories generate the time comparison results of GPS code transfer by the program and send them to BIPM(Bureau International des Poids et Mesures) periodically. In this paper, we introduce the delay features generated while GPS code is transferred and the calibration methods of them. Then, we introduce the tropospheric delay and analyze the results of Saastamoinen model and NATO(North Atlantic Treaty organization) model. Saastamoinen model is the representative tropospheric zenith path delay model and NATO model is applied to the legacy r2cggtts program.

• Fire Science and Engineering
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• v.34 no.3
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• pp.134-140
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• 2020

Nuclear power plants (NPPs) in Korea are required to be maintained using a defense in-depth approach to prevent leakage of radioactive substances outside the plant and allow safe shutdown in the event of a fire. Periodic testing must be conducted to ensure that the fire protection facilities perform as required by the laws for various nuclear reactor types. In June 2017, for the first time in Korea, a nuclear plant, Kori Unit 1, was permanently shut down. It was prepared for decommissioning in accordance with the fire protection regulations imposed by the regulatory body. However, a standard protocol is necessary for systematically establishing the fire protection program for decommissioning of NPPs in the future. Therefore, the nuclear legal systems of countries with many operating nuclear power plants, such as the United States, Japan, Canada, and various European countries, were reviewed and guidelines for establishing a fire protection program for decommissioning NPPs was suggested; the fire protection requirements stated by Reg Guide 1.191 (Decommissioning fire protection program for NPPs during decommissioning and permanent shutdown) were used as a model. Suggestions for establishing legal regulations to optimize fire protection programs and secure basic technology for decommissioning NPPs were also made.