• Title/Summary/Keyword: Defect ratio

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Loss of Aquaporin-3 in Placenta and Fetal Membranes Induces Growth Restriction in Mice

  • Seo, Min Joon;Lim, Ju Hyun;Kim, Dong-Hwan;Bae, Hae-Rahn
    • Development and Reproduction
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    • v.22 no.3
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    • pp.263-273
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    • 2018
  • Aquaporin (AQP) 3, a facilitated transporter of water and glycerol, expresses in placenta and fetal membranes, but the detailed localization and function of AQP3 in placenta remain unclear. To elucidate a role of AQP3 in placenta, we defined the expression and cellular localization of AQP3 in placenta and fetal membranes, and investigated the structural and functional differences between wild-type and AQP3 null mice. Gestational sacs were removed during mid-gestational period and amniotic fluid was aspirated for measurements of volume and composition. Fetuses with attached placenta and fetal membranes were weighed and processed for histological assessment. AQP3 strongly expressed in basolateral membrane of visceral yolk sac cells of fetal membrane, the syncytiotrophoblasts of the labyrinthine placenta and fetal nucleated red blood cell membrane. Mice lacking AQP3 did not exhibit a significant defect in differentiation of trophoblast stem cells and normal placentation. However, AQP3 null fetuses were smaller than their control litter mates in spite of a decrease in litter size. The total amniotic fluid volume per gestational sac was reduced, but the amniotic fluid-to-fetal weight ratio was increased in AQP3 null mice compared with wild-type mice. Glycerol, free fatty acid and triglyceride levels in amniotic fluid of AQP3 null mice were significantly reduced, whereas lactate level increased when compared to those of wild-type mice. These results suggest a role for AQP3 in supplying nutrients from yolk sac and maternal blood to developing fetus by facilitating transport of glycerol in addition to water, and its implication for the fetal growth in utero.

Research for improving quality of SI(System integration) development project (시스템 통합(SI) 구축 사업 품질 향상을 위한 연구)

  • Kim, Seok-Kwan;Ryu, Gab-Sang
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.11 no.3
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    • pp.215-220
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    • 2018
  • This paper limited the participation of large corporations in the mass information market by revising the Software Industry Promotion Act in order to increase business opportunity, equality of opportunity, and capacity building for small and medium sized IT companies. However, it is a fact that the medium and small SW companies have insufficient business capacity and expose various problems such as quality degradation of public information business, inadequate risk management, and deterioration of schedule management. In order to solve this problem, this paper derived the factors of quality deterioration in the system integration project and proposed to carry out the project by using some activities of VISUALIZATION, rigorous test management and Agile Methodology as a solution. Applying these measures to healthcare IT projects developed by midsize / small-sized IT companies has improved communications, improved quantitative progress management and improved project visibility. In addition, it contributed to minimizing defect resolution time, improving the requirement coverage ratio, and shortening unnecessary meeting time.

Portable Piezoelectric Film-based Glove Sensor System for Detecting Internal Defects of Watermelon (수박 내부결함판정을 위한 휴대형 압전형 장갑 센서시스템)

  • Choi, Dong-Soo;Lee, Young-Hee;Choi, Seung-Ryul;Kim, Hak-Jin;Park, Jong-Min;Kato, Koro
    • Journal of Biosystems Engineering
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    • v.33 no.1
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    • pp.30-37
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    • 2008
  • Dynamic excitation and response analysis is an acceptable method to determine some of physical properties of agricultural product for quality evaluation. There is a difference in the internal viscoelasticity between sound and defective fruits due to the difference of geometric structures, thereby showing different vibration characteristics. This study was carried out to develop a portable piezoelectric film-based glove sensor system that can separate internally damaged watermelons from sound ones using an acoustic impulse response technique. Two piezoelectric sensors based on polyvinylidene fluoride (PVDF) films to measure an impact force and vibration response were separately mounted on each glove. Various signal parameters including number of peaks, energy ratio, standard deviation of peak to peak distance, zero-crossing rate, and integral value of peaks were examined to develop a regression-estimated model. When using SMLR (Stepwise Multiple Linear Regression) analysis in SAS, three parameters, i.e., zeros value, number of peaks, and standard deviation of peaks were selected as usable factors with a coefficient of determination ($r^2$) of 0.92 and a standard error of calibration (SEC) of 0.15. In the validation tests using twenty watermelon samples (sound 9, defective 11), the developed model provided good capability showing a classification accuracy of 95%.

The Analysis of Main Factors Which Impact on Operation Rate and Power Production of Landfill Gas Power Plant (매립가스 발전시설의 가동률 및 발전량에 미치는 주요 영향요소 분석)

  • Chun, Seung-Kyu
    • Journal of Korean Society of Environmental Engineers
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    • v.38 no.3
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    • pp.128-134
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    • 2016
  • An analysis of the main factors and its degree of impact on power production is performed against the landfill gas power plant in S landfill site. The number of normal operation (50 MWh & 24 hr) days was 70.9% to the total number of operation days from 2007 to 2014, and the percentage of the actual power production was 79.3% of 3,428,400 MW which is the theoretical maximum estimation. The ratio of factors that accounted for the efficiency of power production are: 44.0% of repairing of the defect and regular servicing, 37.4% of cut-down operation due to hydrogen sulfide, and 18.6% of air pre-heater washing, respectively. Yet, considering that the cut-down operation due to hydrogen sulfide was carried out for only two years, the high concentration of hydrogen sulfide was the most influential factors on landfill gas power production. The long-term power production was analyzed as 35.9 MWh in 2018, and the constant drop is anticipated, resulting in 16.6 MWh by 2028, and under 8.4 MWh in 2038.

The Weldability of $6mm^t$ Primer-coated Steel for Shipbuilding Using $CO_2$ Laser (II) - Dynamic Behavior of Laser Welding Phenomenon and Composition of Porosity and Vaporized-particle - ($6mm^t$조선용 프라이머 코팅강판의 $CO_2$레이저 용접성 (II) - 레이저 용접현상의 동적거동과 기공 및 증발입자의 조성 -)

  • Kim, Jong-Do;Park, Hyun-Joon
    • Journal of Welding and Joining
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    • v.24 no.2
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    • pp.71-78
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    • 2006
  • It has been reported that good quality weld beads are not easily obtained during the $CO_2$ CW laser welding of primer coated plate. However, by introducing a small gap clearance in the lap position, the zinc vapor can escape through it and sound weld beads can be acquired. Therefore, this study examines for keyhole behavior by observing the laser-induced plasma and investigates the relation between keyhole behavior and formation of weld defect. Laser-induced plasma has accompanied with the vaporizing pressure of zinc ejecting from keyhole to surface of primer coated plate. This dynamic behavior of plasma was very unstable and this instability was closely related to the unstable motion of keyhole during laser welding. As a result of observing the composition of porosity, much of Zn element was found from inner surface of porosity. But Zn was not found from the dimple structure fractured at the weld metal. By analyzing of vaporizing element in laser welding, a component ratio of Zn was decreased by introducing a small gap clearance. Therefore we can prove that the major cause of porosity is the vaporization of primer in lap position. Mechanism of porosity-formation is that the primer vaporized from the lap position accelerates dynamic behavior of the key hole and the bubble separated from the key hole is trapped in the solidification boundary and romaines as porosity.

Characteristic of Soil and Cambial Electrical Resistance for Investigation on Defect Cause of Planting Tree in Apartment

  • Cho, Chi-Woung;Yoo, Sun-Ah;Kim, Jeong-Ho
    • Journal of Environmental Science International
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    • v.21 no.11
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    • pp.1307-1320
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    • 2012
  • The purpose of this paper is to provide information on planting construction for healthy plant growth. To achieve this purpose, this study analyzed the planting type, planting density, withering rate, soil characteristics, and cambium electrical resistance (CER) of withered trees in an apartment complex with a high withering rate. The major plant groups examined consisted of native broad-leaved tree species (39.3%), native narrow-leaved tree species (24.2%), and native broad-leaved - exotic narrow-leaved tree species (16.4%). The planting density of the green area, where trees were planted from 0.0 to 0.3 trees per unit area, was measured as 98.4%. Withered trees were found in 19 of the 20 planted species, and the withering rate was 41.8% (610 withered/1,461 planted). Withering rates for tree species were measured as follows: Sophora japonica and Salix babylonica (100.0%), Magmolia denudata (84.3%), Lindera obtusiloba (74.7%), cornus kousa (69.3%), acer triflorum (69.2%), diospyros kaki (66.7%), Prunus yedoensis (62.8%), Acer palmatum (52.6%), Prunus armeniaca (51.1%), Chaenomeles sinensis (43.7%), Ginkgo biloba (40.9%), Zelkova serrata (31.0%), Cornus officinalis (28.6%), Taxus cuspidata (25.6%), Pinus densiflora (21.4%), Pinus parviflora (15.2%), Pinus strobus (14.6%), and Abies holophylla (10.3%). Soil chemical analyses for 18 samples revealed that as the withering rate increased, the following occurred: (a) the ratio of silt and clay in soil increased; (b) the soil pH, organic matter rate, nitrogen, available phosphorus, and cation exchange capacity (CEC) in samples were graded as "inadequate," based on the plant grading evaluation; and (c) the NaCl and cation exchange capacity were evaluated as "somewhat satisfactory." The measurement of CER for withering rate shows electrical resistance for higher withering rate are higher, which could predict that a tree will not grow well.

Mode II Fracture Toughness of Hybrid FRCs

  • Abou El-Mal, H.S.S.;Sherbini, A.S.;Sallam, H.E.M.
    • International Journal of Concrete Structures and Materials
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    • v.9 no.4
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    • pp.475-486
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    • 2015
  • Mode II fracture toughness ($K_{IIc}$) of fiber reinforced concrete (FRC) has been widely investigated under various patterns of test specimen geometries. Most of these studies were focused on single type fiber reinforced concrete. There is a lack in such studies for hybrid fiber reinforced concrete. In the current study, an experimental investigation of evaluating mode II fracture toughness ($K_{IIc}$) of hybrid fiber embedded in high strength concrete matrix has been reported. Three different types of fibers; namely steel (S), glass (G), and polypropylene (PP) fibers were mixed together in four hybridization patterns (S/G), (S/PP), (G/PP), (S/G/PP) with constant cumulative volume fraction ($V_f$) of 1.5 %. The concrete matrix properties were kept the same for all hybrid FRC patterns. In an attempt to estimate a fairly accepted value of fracture toughness $K_{IIc}$, four testing geometries and loading types are employed in this investigation. Three different ratios of notch depth to specimen width (a/w) 0.3, 0.4, and 0.5 were implemented in this study. Mode II fracture toughness of concrete $K_{IIc}$ was found to decrease with the increment of a/w ratio for all concretes and test geometries. Mode II fracture toughness $K_{IIc}$ was sensitive to the hybridization patterns of fiber. The (S/PP) hybridization pattern showed higher values than all other patterns, while the (S/G/PP) showed insignificant enhancement on mode II fracture toughness ($K_{IIc}$). The four point shear test set up reflected the lowest values of mode II fracture toughness $K_{IIc}$ of concrete. The non damage defect concept proved that, double edge notch prism test setup is the most reliable test to measure pure mode II of concrete.

Distribution of Basal Cell Carcinoma and Squamous Cell Carcinoma by Facial Esthetic Unit

  • Choi, Jung Hun;Kim, Young Joon;Kim, Hoon;Nam, Sang Hyun;Choi, Young Woong
    • Archives of Plastic Surgery
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    • v.40 no.4
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    • pp.387-391
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    • 2013
  • Background The most common cutaneous malignant masses are basal cell carcinoma (BCC) and squamous cell carcinoma. The predominant site of a malignant mass is the face, which has many opportunities to be exposed to ultraviolet radiation. However the predilection sites of malignant masses have been equivocal due to the use of general regions, rather than anatomical landmarks, in surveys. A facial esthetic unit is an anatomical site classified as an area of similar facial contour characteristics that can be distinguished from other areas. The purpose of this study is to determine widely accepted anatomical landmarks using the esthetic unit. Methods We retrospectively analyzed 118 cases of malignant masses in our clinic from January 2005 to October 2012. We evaluated the patients' age, gender, and predilection site of the malignant mass by esthetic unit through pathology, medical records and patient photographs. We mapped the occurrence site of the malignant mass on schematic drawings of the esthetic units. Results Most of the malignant masses were BCC. The ratio of males to females was 1:1.41. The frequent predilection site of a malignant mass was on the nasal unit (33.1%), followed by the buccal unit (11.0%). Primary closure was the most common method of repairing a surgical defect (38.9%), followed by a local flap (35.5%). Conclusions This review described the relationship between clinical characteristics and esthetic units by proposing objective predilection sites for malignant masses, which can be used commonly as a framework in the study of malignant masses by unifying equivocal occurrence sites.

Multifactorial analysis of the surgical outcomes of giant congenital melanocytic nevi: Single versus serial tissue expansion

  • Kim, Min Ji;Lee, Dong Hwan;Park, Dong Ha
    • Archives of Plastic Surgery
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    • v.47 no.6
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    • pp.551-558
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    • 2020
  • Background Giant congenital melanocytic nevus (GCMN) is a rare disease, for which complete surgical resection is recommended. However, the size of the lesions presents problems for the management of the condition. The most popular approach is to use a tissue expander; however, single-stage expansion in reconstructive surgery for GCMN cannot always address the entire defect. Few reports have compared tissue expansion techniques. The present study compared single and serial expansion to analyze the risk factors for complications and the surgical outcomes of the two techniques. Methods We retrospectively reviewed the medical charts of patients who underwent tissue expander reconstruction between March 2011 and July 2019. Serial expansion was indicated in cases of anatomically obvious defects after the first expansion, limited skin expansion with two more expander insertions, or capsular contracture after removal of the first expander. Results Fifty-five patients (88 cases) were analyzed, of whom 31 underwent serial expansion. The number of expanders inserted was higher in the serial-expansion group (P<0.001). The back and lower extremities were the most common locations for single and serial expansion, respectively (P =0.043). Multivariate analysis showed that sex (odds ratio [OR], 0.257; P=0.015), expander size (OR, 1.016; P=0.015), and inflation volume (OR, 0.987; P=0.015) were risk factors for complications. Conclusions Serial expansion is a good option for GCMN management. We demonstrated that large-sized expanders and large inflation volumes can lead to complications, and therefore require risk-reducing strategies. Nonetheless, serial expansion with proper management is appropriate for certain patients and can provide aesthetically satisfactory outcomes.

Life Estimation of Organic Light Emission Diode by Accelerated Test (유기발광(有機發光) 다이오드의 가속(加速) 수명(壽命) 시험(試驗)에 관한 연구(硏究))

  • Choi, Young-Tei;Cho, Jai-Rip
    • Proceedings of the Korean Society for Quality Management Conference
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    • 2010.04a
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    • pp.262-268
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    • 2010
  • Organic light emitting diode is developed fast from 1963 after discovering electric light emitting phenomenon. First PMOLED(passive matrix OLED) product is manufactured and AMOLED(active matrix OLED) using TFT(thin film ransistor) is now in the center. PMOLED is mainly mounted at sub display. but AMOLED is mounted at main display. Also AMOLED expand the market to PMP(portable multimedia players), navigation and TV. Even thought OLED's market is opening to many applications, OLED is worried about lifetime until now. That's appeared in market in a very short time and is not known well about result of OLED's lifetime and reliability test. And there is no standard ssessment method and not enough study to standardization the method. A study's purpose is reduce the time for life test by accelerated current and it can do production possible design by accelerated life model in design phase. It's must be add to process variables and design variables(like ratio of light emitting, organic material structure, condition of aging, etc) to make the best use of supplied accelerated lifetime model in this paper. In terms of lifetime it needs each criterion of applications because of image sticking. In conclusion, it's possible to discover new defect because there is not much time to be opened in market and develop a method of manufacturing process & materials, so we need to study on the subject of this paper continuously.

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