• 약학회지
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• 제26권3호
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• pp.157-161
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• 1982

최근 천연물 의약품의 양약제제화와 더불어 그제제의 확인및 함량검토를 위한 공정법이 날로 그 필요성을 더해 가고 있다. 천연물 의약품은 일반 양약제제와는 달리 그 조성이 복잡하고 대부분은 그 성분조차 파악되고 있지 못한 실정이다. 더구나 일부 그 조성이 밝혀진 천연물조차 그 품종, 부위, 또는 산지등에 따라 조성이 매우 다양하므로 함량을 검토하는데는 많은 문제점을 안고 있다. 연자는 이러한 문제점을 개선하는 방법의 하나로 녹용제제를 대상으로 그 확인 및 함량 시험법을 연구하였다. 녹용은 아직까지 그 유효성분리 확실히 밝혀진 바가 없으므로 본 실험에서는 녹용중 amino acid의 pattern분석 및 glycine의 함량을 검토함으로써 확인 및 정량법을 연구하였다.

• 농업과학연구
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• 제34권1호
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• pp.37-46
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• 2007

본 연구는 사슴뿔이 발생되지 않는 암사슴의 전두골의 뿔 발생예정지역의 좌우 양측골막에 $CaCl_2$ 용액의 주사로 인위적인 뿔 발생유도에 의한 뿔 발생유도율 및 뿔 생산량을 조사하고, 암사슴의 뿔 발생유도가 번식에 미치는 영향을 구명하고자 엘크 암사슴 11두를 공시하여 얻어진 결과는 다음과 같다. 엘크 암사슴에 $CaCl_2$ 처리 농도에 따른 뿔 발생유도는 $CaCl_2$ 30 및 50 % 처리구가 15 % 처리구보다 뿔 발생유도율이 높았으며, 뿔의 생산량에 있어서는 $CaCl_2$ 30 % 처리구가 15 및 50 % 처리구보다 많은 사슴뿔의 생산량을 보였고, $CaCl_2$ 30 % 처리구내 투여량에 있어서는 1.5 ml 및 2.0 ml 투여가 다른 투여수준에 비하여 뿔의 길이와 생산량이 우수 하였다. 암사슴 뿔의 발생유도 후에도 분만율은 75 ~ 100 % 로 번식에는 전혀 영향을 미치지 않는 것으로 판단되었으며, 암사슴의 재생뿔 발생율은 총 11두중 5두가 발생하여 45.0 %로 불규칙한 발생율을 보였다. 이상의 결과에서 $CaCl_2$ 용액 처리에 의한 엘크 암사슴의 뿔 발생유도 및 뿔 생산량에 있어서는 $CaCl_2$ 용액의 농도는 30 %가 적절하고, 투여수준은 1.5 및 2.0 ml 주사시 뿔의 발생유도율 및 생산량을 증대시킬 수 있을 것으로 생각되며, 인위적인 암사슴 뿔의 유도시에도 번식에는 영향을 미치지 않는 것으로 조사되었다.

• 동의생리병리학회지
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• 제17권1호
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• pp.157-164
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• 2003

Cervi Parvum Cornu(CPC) is that the young horn of deer family and has been traditionally used as a medicine in Eastern. The purpose of present study was to investigate the effects of CPC on cell cycle progression and its molecular mechanism in human periodontal ligament cells (HPOLC). In cell proliferation assay, 1 ng/ml, 10 ng/ml, 100 ng/ml, 1 ㎍/ml and 10 ㎍/ml of CPC were used, all treatment groups increased the cell growth. Maximal cell proliferation was observed in cells exposed to 100 ng/ml of CPC at 4 day, and 10 ng/ml and 100 ng/ml of CPC at 6 days. S phase was increased and G1 phase was decreased in the group treated with 100 ng/ml of CPC in cell cycle analysis. The protein levels of cyclin D1 were not changed, but the levels of cyclin E, cdk 2, cdk 4 and cdk 6 were increased. The protein levels of p21, pRb were decreased as compared to that of control group, but the levels of p53 was not changed in the cells both treated with CPC Md untreated. These results suggested that CPC increases the cell proliferation and cell cycle progression in HPDLC, which is linked to an increased cellular levels of cyclin E, cdk 2, cdk 4 and cdk 6, and decreased the levels of p53, p21.

• 복식
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• 제63권3호
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• pp.1-16
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• 2013

Xiognu people were the first of the Central-Asian nomads to establish a nation in 209 B.C. They always moved around looking for places to breed their animals and fertile grounds, so they wore clothes made of fur and leather and covered their tents with felt from the livestock. This research studies on the literatures, costumes and the achievement of archaeological excavation. Furthermore, to investigate on costumes excavated of Xiongnu, we visited the Mongolian National Museum and the Hermitage Museum. A corn-hat made of felt, a felt hat with ear flaps and a golden crown with a bird on the top were unearthed from a tomb of Xiongnu in Inner mongolia. Women usually wore pigtails, and men wore pigtails or ponytails but they cut their hair short when holding a funeral. Many pigtails discovered in Noyon uul tombs can be considered as their funeral customs. The Xiongnu wore a round or v-neck caftan attached straight sleeves reaching knees in the left folded style, and because they always rode horses, having the length of the caftan not go past their buttocks would have made it more convenient for them. During the period of Western Han, Ho refered to Xiongnu and it became a common name for northern races. They used leather belts and an animal-designed buckle was found. Women commonly rouged their cheeks for a vivid and cute look, and many ornaments were excavated including bracelets, rings and decorations made of gold, silver, copper and jade, among which there were hair ornaments used to identify one's class. A horse pattern with wings and a horn of Golmod T20 was substitution for the Schythian use of deer. Patterns or shape of unearthed articles present in the Xiongnu culture in Noyon uul had a close relationship with Altaic, Greek and Persian cultures. The Xiongnu clothing was made of animals' skin and fur, woolen textiles and felt. It was folded to the left for upper garments, and the pants were adjusted using a belt and shoes were made of leather, which was very suitable for protection against the cold and horse riding. Mobility played a significant role in their clothing.

• 한국버섯학회지
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• 제14권1호
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• pp.1-5
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• 2016

이 연구는, 느타리버섯과 풀버섯만 재배하던 캄보디아에서 영지버섯, 목이버섯 그리고 표고버섯 등과 같은 여러 종류의 고온성 버섯들의 종균을 생산하고, 캄보디아에서 생산되는 경제적이고 효율적인 새로운 버섯배지를 찾기 위해 시도되었다. 종균 및 버섯재배 배지로, 여러 종류의 유기물찌꺼기, 곡물, 그리고 톱밥이 사용되었다. 고무나무 톱밥배지에서 자란 균사 (10.9 cm/15일)는 곡물배지에서 자란 균사 (11.2 cm/15일)에 비해 성장이 조금 느렸지만, 고무나무 톱밥은 낮은 가격 및 취급의 용이성이 있어, 비싼 곡물종균을 대치할 수 있는 매우 적절한 배지인 것으로 나타났다. 버섯생산을 위해서, 고무나무톱밥(60.8% BE), 사탕수수박(60% BE), 그리고 아카시아나무 톱밥 등에 미강과 탄산칼슘을 혼합하여 사용하였는데, 사탕수수박과 고무나무 톱밥은 매우 비슷한 높은 생물학적 효율(BE)을 보여주었고, 아카시아나무 톱밥은 비교적 낮은 22.4%의 생물학적 효율을 보여주었다. 따라서 낮은 가격에 구입할 수 있는 아카시아톱밥이 현재 사용되고 있는 높은 가격의 배지들과 혼합하여 사용된다면 매우 가능성이 높은 새로운 배지가 될 수 있을 것으로 보였다. 현재, 사용되고 있는 톱밥의 가격 (20 kg 고무나무톱밥=6500 Riel 혹은 1.6 USD)과 비교했을 때, 아카시아톱밥의 가격(20 kg=1000Riel 혹은 0.25USD)이 매우 낮아 버섯의 생산에 투자되는 비용을 크게 줄여 경제성을 높일 수 있을 것으로 사료된다.

• 혜화의학회지
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• 제9권1호
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• pp.513-545
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• 2000

I. Introduction Bi(痺) means blocking. It can reach at the joints or muscles or whole body and make pains. Numbness and movement disorders. BiJeung can be devided into SilBi and HeoBi. In SilBi there are PungHanSeupBi, YeolBi and WanBi. In HeoBi, there are GiHyeolHeoBi, EumHeoBi and YangHeoBi. The common principle for the treatment of BiJeung is devision of the chronic stage and the acute stage. In the acute stage, BiJeung is usually cured easily but in the chronic stage, it is difficult. In the terminal stage, BiJeung can reach at the internal organs. BiJeung is one kind of symptoms making muscles, bones and jonts feel pain, numbness or edema. For example it can be gout or SLE etc. Many famous doctors studied medical science by their fathers or teachers. So the history of medical science is long. So I studied ${\ll}Bijeungjujip{\gg}$. II. Final Decision 1. BanSuMun(斑秀文) thought that BiJeung can be cured by blocking of blood stream. So he insisted that the important thing to cure BiJeung is to improve the blood stream. He usually used DangGuiSaYeokTang(當歸四逆湯), DangGuiJakYakSanHapORyeongSan, DoHong-SaMulTang(桃紅四物湯), SaMyoSanHapHeuiDongTang and HwangGiGyeJiOMulTang. 2. JangGeonBu(張健夫) focused on soothing muscles and improving blood seam. So he used many herbs like WiRyeongSeon(威靈仙), GangHwal(羌活), DokHwal(獨活), WooSeul(牛膝), etc. Especially he pasted wastes of the boiled herbs. 3. OSeongNong(吳聖農) introduced four rules to treat arthritis. So he usually used SeoGak-SanGaGam(犀角散加減), BoYanHwanOTang(補陽還五湯), ODuTang(烏頭湯), HwangGiGyeJiOMulTang. 4. GongJiSin thought disk hernia as one kind of BiJeung. And he said that Pung can hurt upper limbs and Seup can hurt lower limbs. He used to use GyeJiJakYakJiMoTang(桂枝芍藥知母湯). 5. LoJiJeong(路志正) introduced four principles to treat BiJeung. He used BangPungTang(防風湯), DaeJinGuTang) for PungBi(風痺), OPaeTang(烏貝湯) for HanBi(寒痺), YukGunJaTang(六君子湯) for SeupBi(濕痺) and SaMyoTang(四妙湯), SeonBiTang(宣痺湯), BaekHoGaGyeTang(白虎加桂湯) for YeolBi(熱痺). 6. GangChunHwa(姜春華) discussed herbs. He said SaengJiHwang(生地黃) is effective for PungSeupBi and WiRyungSun(威靈仙) is effective for the joints pain. He usually used SipJeonDaeBoTang(十全大補湯), DangGuiDaeBoTang(當歸大補湯), YoukGunJaTang(六君子湯) and YukMiJiHwanTang(六味地黃湯). 7. DongGeonHwa(董建華) said that the most important thing to treat BiJeung is how to use herbs. He usually used CheonO(川烏), MaHwang(麻黃) for HanBi, SeoGak(犀角) for YeolBi, BiHae) or JamSa(蠶沙) for SeupBi, SukJiHwang(熟地黃) or Vertebrae of Pigs for improving the function of kidney and liver, deer horn or DuChung(杜沖) for improving strength of body and HwangGi(黃?) or OGaPi(五加皮) for improving the function of heart. 8. YiSuSan(李壽山) devided BiJeung into two types(PungHanSeupBi, PungYeolSeupBi). And he used GyeJiJakYakJiMoTang(桂枝芍藥知母湯) for the treatment of gout. And he liked to use HwanGiGyeJiOMulTangHapSinGiHwan 枝五物湯合腎氣丸) for the treat ment of WanBi(頑痺). 9. AnDukHyeong(顔德馨) made YongMaJeongTongDan(龍馬定痛丹)-(MaJeonJa(馬錢子) 30g, JiJaChung 3g, JiRyong(地龍) 3g, JeonGal(全蝎) 3g, JuSa(朱砂) 0.3g) 10. JangBaekYou(張伯臾) devided BiJeung into YeolBi and HanBi. And he focused on improving blood stream. 11. JinMuO(陳茂梧) introduced anti-wind and dampness prescription(HoJangGeun(虎杖根) 15g, CheonChoGeun 15g, SangGiSaeng(桑寄生) 15g, JamSa(蠶絲) 15g, JeMaJeonJa(制馬錢子) 3g). 12. YiChongBo(李總甫) explained basic prescriptions to treat BiJeung. He used SinJeongChuBiEum(新定推痺陰) for HaengBi(行痺), SinJeongHwaBiSan(新定化痺散) for TongBi(痛痺), SinJeongGaeBiTang(新定開痺湯) for ChakBi(着痺), SinJeongCheongBiEum(新定淸痺飮) for SeupYeolBi(濕熱痺), SinRyeokTang(腎瀝湯) for PoBi(胞痺), ORyeongSan for BuBi(腑痺), OBiTang(五痺湯) for JangBi(臟痺), SinChakTang(腎着湯) for SingChakByeong(腎着病). 13. HwangJeonGeuk(黃傳克) used SaMu1SaDeungHapJe(四物四藤合制) for the treatment of a acute arthritis, PalJinHpPalDeungTang(八珍合八藤湯) or BuGyeJiHwangTangHapTaDeungTang(附桂地黃湯合四藤湯) for the chronic stage and ByeolGapJeungAekTongRakEum(鱉甲增液通絡飮) for EumHeo(陰虛) 14. GaYeo(柯與參) used HwalRakJiTongTang(活絡止痛湯) for shoulder ache, SoJongJinTongHwalRakTank(消腫鎭痛活絡湯) for YeolBi(熱痺), LiGwanJeolTang(利關節湯) for ChakBi(着痺), SinBiTang(腎痺湯) for SinBi(腎痺) and SamGyoBoSinHwan(三膠補腎丸) for back ache. 15. JangGilJin(蔣길塵) liked to use hot-character herbs and insects. And he used SeoGeunLipAnTang(舒筋立安湯) as basic prescription. 16. RyuJangGeol(留章杰) used GuMiGangHwalTang(九味羌活湯) and BangPungTang(防風湯) at the acute stage, ODuTang(烏頭湯) or GyeJiJakYakJiMoTang(桂枝芍藥知母湯) for HanBi of internal organs, YangHwaHaeEungTang(陽和解凝湯) for HanBi, DokHwalGiSaengTang(獨活寄生湯), EuiYiInTang(薏苡仁湯) for SeupBi, YukGunJaTang(六君子湯) for GiHeoBi(氣虛痺) and SeongYouTang(聖兪湯) for HyeolHeoBi(血虛痺). 17. YangYuHak(楊有鶴) liked to use SoGyeongHwalHyelTang(疏經活血湯) and he would rather use DoIn(桃仁), HongHwa(紅花), DangGui(當歸), CheonGung(川芎) than insects. 18. SaHongDo(史鴻濤) made RyuPungSeupTang(類風濕湯)-((HwangGi 200g, JinGu 20g, BangGi(防己) 15g, HongHwa(紅花) 15g, DoIn(桃仁) 15g, CheongPungDeung(靑風藤) 20g, JiRyong(地龍) 15g, GyeJi(桂枝) 15g, WoSeul(牛膝) 15g, CheonSanGap(穿山甲) 15g, BaekJi(白芷) 15g, BaekSeonPi(白鮮皮) 15g, GamCho(甘草) 15g).