• Journal of Veterinary Science
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• 제21권4호
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• pp.65.1-65.13
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• 2020

Background: Aleutian mink disease virus (AMDV) causes major economic losses in fur-bearing animal production. The control of most AMDV outbreaks is complex due to the difficulties of establishing the source of infection based only on the available on-farm epidemiological data. In this sense, phylogenetic analysis of the strains present in a farm may help elucidate the origin of the infection and improve the control and biosecurity measures. Objectives: This study had the following aims: characterize the AMDV strains from most outbreaks produced at Spanish farms between 2012-2019 at the molecular level, and assess the utility of the combined use of molecular and epidemiological data to track the possible routes of infection. Methods: Thirty-seven strains from 17 farms were partially sequenced for the NS1 and VP2 genes and analyzed phylogenetically with other strains described worldwide. Results: Spanish AMDV strains are clustered in four major clades that generally show a good geographical correlation, confirming that most had been established in Spain a long time ago. The combined study of phylogenetic results and epidemiological information of each farm suggests that most of the AMDV outbreaks since 2012 had been produced by within-farm reservoirs, while a few of them may have been due to the introduction of the virus through international trade. Conclusions: The combination of phylogenetic inference, together with epidemiological data, helps assess the possible origin of AMDV infections in mink farms and improving the control and prevention of this disease.

• Parasites, Hosts and Diseases
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• 제48권1호
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• pp.43-48
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• 2010

Cryptosporidium and Giardia are 2 protozoan parasites responsible for waterborne diseases outbreaks worldwide. In order to assess the prevalence of these protozoans in drinking water samples in the northern part of Portugal and the risk of human infection, we have established a long term program aiming at pinpointing the sources of surface water, drinking water, and environmental contamination, working with the water-supply industry. Total 43 sources of drinking water samples were selected, and a total of 167 samples were analyzed using the Method 1623. Sensitivity assays regarding the genetic characterization by PCR and sequencing of the genes, 18S SSU rRNA, for Cryptosporidium spp. and $\beta$, -giardin for G. duodenalis were set in the laboratory. According to the defined criteria, molecular analysis was performed over 4 samples. Environmental stages of the protozoa were detected in 25.7% (43 out of 167) of the water samples, 8.4% (14 out of 167) with cysts of Giardia, 10.2% (17 out of 167) with oocysts of Cryptosporidium and 7.2% (12 out of 167) for both species. The mean concentrations were 0.1-12.7 oocysts of Cryptosporidium spp. per 10 L and 0.1-108.3 cysts of Giardia duodenalis per 10 L. Our results suggest that the efficiency in drinking water plants must be ameliorated in their efficiency in reducing the levels of contamination. We suggest the implementation of systematic monitoring programs for both protozoa. To authors' knowledge, this is the first report evaluating the concentration of environmental stages of Cryptosporidium and Giardia in drinking water samples in the northern part of Portugal.

• Asian-Australasian Journal of Animal Sciences
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• 제31권2호
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• pp.225-229
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• 2018

Objective: This experiment was designed to evaluate the effect of supplementation with soybean or canola oil on milk production and the composition of long chain fatty acids as well as weight changes in the goats and their kids. Methods: Thirty nine mulitparous crossed Alpine${\times}$Nubian goats (initial body weight [BW] $43.5{\pm}1.7kg$) from the day of parturition were assigned to the treatments: grazing control (n = 15); grazing plus 20 mL/goat/d of supplemental soybean oil (n = 12); and grazing plus 20 mL/goat/d of supplemental canola oil (n = 12) from November 26, 2014 to March 7, 2015. The planned contrasts were: CI (control vs supplemented with oils); CII (soybean vs canola oil) to compare the treatment effects. Results: The vegetable oil supplementation reduced weight losses in lactating goats (CI: -0.060 vs 0.090 kg/d; p = 0.03) but did not improve milk production or affect kids' growth. The content of C4, C6, C8, C10, C11, C14, and C18:1n9t in the milk was increased (p<0.05) with respect to control. However, C12, C14, C16, C18, C18:1n9c, C18:2n6c, and C18:3n3 were reduced (p<0.05) in supplemented goats. Conjugated linoleic acid (CLA) was increased (p<0.05) in goats supplemented with oils compared to the control group. Conclusion: Supplementation with 20 mL/d of soybean or canola oil did not affect milk production or kids' performance; however, it increased CLA concentration and reduced the reduced weight losses in lactating goats.

• 철학연구
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• 제125호
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• pp.7-30
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• 2019

본고는 『천 개의 고원』의 서문인 「리좀」을 바탕으로 하여, 리좀을 이해하기 위한 핵심개념 중의 하나인 '미리우(milieu)'를 '리좀적 중도'이자 일종의 '철학적 중도'로 규명하는 것을 목적으로 한다. 글의 구체적인 전개과정은 다음과 같다. 먼저, 텍스트에서 서양 전통 형이상학의 나무-뿌리 형태의 책에 대한 대안으로 제시되고 있는 리좀-수로 형태, '책-리좀'의 사유 체계를 검토한다. 다음으로, 리좀적 사유가 어떻게 '길'이 되고, 동양적 '도(Tao, 道)'와 만나 리좀적 중도가 되며 철학적 중도로 해석될 수 있는지를 밝힌다. 다른 한편으로, 본고는 리좀적 사유가 우리로 하여금 내재적 차이와 타자에 대한 이해를 보다 깊이 하도록 하며, 또한 공(空)한 다양체의 원리에 따른 실천적 삶의 수행을 돕는 방법으로서의 의의를 가짐을 조명한다. 이 연구는 동양의 중도의 사유를 현시대에 적합하게 풀어내어 철학적으로 실천하는 일에 기여할 수 있을 것으로 기대된다.

• 충청수학회지
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• 제26권4호
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• pp.749-756
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• 2013

In this paper, we consider a diffusive delayed predator-prey model with Beddington-DeAngelis type functional response under homogeneous Neumann boundary conditions, where the discrete time delay covers the period from the birth of immature preys to their maturity. We investigate the global existence of nonnegative solutions and the long-term behavior of the time-dependent solution of the model.

• Communications for Statistical Applications and Methods
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• 제13권3호
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• pp.587-605
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• 2006

Recent results in applied statistics have shown that the presence of periodicities in time series may influence the estimation and testing of the fractional differencing parameter. In this article, we provide further evidence on the issue by using several procedures of fractional integration. The results show that in the presence of periodicities, the order of integration can be erroneously detected. An empirical application in the context of seasonal data is also carried out at the end of the article.

• Journal of Plant Biology
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• 제28권4호
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• pp.305-315
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• 1985

Morphological variations within the species of Scenedesmus in Korea, S. armatus and 2 strains of S. quadricauda were investigated. Taxonomic characters such as length of long spine, ridge, unicell-colony transformation, and colony types were compared. The length of long spine was constant, whereas the distribution of the spine varied with the age of culture. Ridge and short spine in S. armatus occurred constantly, whereas those in S. quadricauda varied with the composition of the media and age of culture. Strains CY-1 and CY-2 showed 6 different colony types in the stationary culture, whereas S. armatus formed only two types, armatus and armatus-longus types. All strains showed unicell-colony transformation. The cell became minimum when the daughter cell was released, and reached maximum at division.

• 전자통신동향분석
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• 제38권3호
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• pp.38-46
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• 2023

The value of living a long and healthy life without suffering has increased owing to aging populations, transition to welfare societies, and global interest in health deriving from the novel coronavirus disease pandemic. New drug development has gained attention as both a tool to improve the quality of life and high-value market, with blockbuster drugs potentially generating over 10 billion dollars in annual revenue. However, for newly discovered substances to be used as drugs, various properties must be verified over a long period in a time-consuming and costly process. Recently, the development of artificial intelligence technologies, such as deep and reinforcement learning, has led to significant changes in drug development by enabling the effective identification of drug candidates that satisfy desired properties. We explore and discuss trends in artificial intelligence for de novo drug design.

• 서비스연구
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• 제12권3호
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• pp.144-157
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• 2022

본 연구는 어디서부터 어디까지 가짜뉴스(Fake News)로 볼 것인가에 대해 여전히 다른 기준과 관점을 가지고 접근하고 있는 상황에서 프랑스 '정보조작대처법(Les propositions de loi contre la manipulation de l' information)' 사례를 통해 수시로 등장하는 가짜뉴스 규제에 대한 국내언론 보도에 대한 문제점을 지적하는 것에서 시작했다. 소셜네트워크서비스(Social Network Service) 시대에 언론은 무엇이고, 뉴스는 무엇이며, 기자는 누구인가에 대한 답은 갈수록 어렵다. 이번 연구에서 살펴 본 가짜뉴스의 오랜 역사와 확산배경을 검토하면서 가짜뉴스에 대한 개념과 범위도 확실하지 않은 상황에서 단순히 하나의 잣대로 재단하거나 처벌하거나 규제하거나 통제하거나 판단할 수 없음을 확인했다. 법이 정하고 있는 '표현의 자유(Freedom of Expression)' 관점에서 우리는 누구나 자신의 의견을 자유롭게 드러낼 수 있는 권한을 갖고 있다. 또한 온라인(On-line) 공간은 가짜뉴스를 생성하고 확산하는 곳이기도 하지만 동시에 해독제로 작용할 여지가 충분하다. 결국 양질의 '진짜뉴스' 가 보다 많이 쏟아질 수 있도록 하는 미디어 환경을 조성하면서, 사상의 자유시장에서 다양한 뉴스 간에 균형 잡힌 경쟁을 통해, 우리 스스로가 신뢰성 있는 정보를 판단할 수 있는 능력을 기를 수 있도록 하는 장기적인 대응만이 인간의 역사와 함께 오래 지속되고 있는 가짜뉴스의 피해에 대한 대안일 것이다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2005년도 학술발표회(1)
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• pp.219-220
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• 2005