• 제목/요약/키워드: David

검색결과 1,565건 처리시간 0.022초

한국 동굴의 환경파괴

  • Kesner, David W.
    • 한국동굴학회:학술대회논문집
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    • 한국동굴학회 1998년도 제 10차 ASIA CAVING 대회 -발표요지문-
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    • pp.75.1-75
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    • 1998
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CANADIAN CAVES

  • Selvadurai, David D.N.
    • 한국동굴학회:학술대회논문집
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    • 한국동굴학회 1998년도 제 10차 ASIA CAVING 대회 -발표요지문-
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    • pp.87-88
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    • 1998
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Current Status of Immunotherapeutic Strategies for Central Nervous System Tumors

  • Yang, Meng-Yin;Khan-Farooqi, Haumith;Prins, Robert M.;Liau, Linda M.
    • Journal of Korean Neurosurgical Society
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    • 제40권4호
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    • pp.217-226
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    • 2006
  • Malignant gliomas are the most common type of primary brain tumor and are in great need of novel therapeutic approaches. Advances in treatment have been very modest, significant improvement in survival has been lacking for many decades, and prognosis remains dismal. Despite "gross total" surgical resections and currently available radio-chemotherapy, malignant gliomas inevitably recur due to reservoirs of notoriously invasive tumor cells that infiltrate adjacent and non-adjacent areas of normal brain parenchyma. In principle, the immune system is uniquely qualified to recognize and target these infiltrative pockets of tumors cells, which have generally eluded conventional treatment approaches, In the span of the last 10 years, our understanding of the cancer-immune system relationship has increased exponentially; and yet we are only beginning to tease apart the intricacies of the central nervous system and immune cell interactions. This article reviews the complex associations of the immune system with brain tumors. We provide an overview of currently available treatment options for malignant gliomas, existing gaps in our knowledge of brain tumor immunology, and strategies that might be exploited for improved design of "custom immunotherapeutics." We will also examine major new immunotherapy approaches that are being actively investigated to treat patients with malignant glioma, and identify some current and future research priorities in this area.

화가 Jacques-Louis David의 초상화에 묘사된 18세기말 남·여 복식의 변화와 사상적(思想的) 조류(潮流) (The Changes of 18th Century Costume Depicted in the Portraitures of Painter Jacques-Louis David in Light of the Ideological Transition)

  • 배수정
    • 복식
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    • 제63권2호
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    • pp.82-97
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    • 2013
  • The aim of this thesis is to investigate the change of men and women's costumes in late 18th century and early 19th century in view of its ideological streams by examining the portraits of the painter Jacques-Louis David. The method of investigation used was to select 29 pieces of portraits from 1766 to 1825, which showed the clear descriptions about the costumes and to analyze the costume's forms, ornaments and the headdress. The category was divided into 3 stages in terms of the changes in costume. The first stage, from 1766 until 1788, is the one of turnaround from the Rococo costume to the early neoclassical one. The typical Rococo costume was incrementally transformed into a simpler design without ornaments, and then natural silhouette in men and women's costumes started to appear from 1783 until 1788. This might be attributed to the neoclassical trend which was affected by the enlightenment ideology. The second stage, from 1788 until 1795, is the period of change from the costume of the early neoclassic style to the typical neoclassic style and also the time from the 1793 to 1795 was regarded as the peak of neoclassic style when the effect of enlightenment began to decrease while one of neoclassicism exerted its strong influence on the costume. The third stage, from 1795 until 1825, similar to the previous neoclassical style was also notable in its turning into producing the empire dress of Empire style. From 1820 on, it was a period that showed signs of influence from romanticism while the effect of neoclassicism started to become more diminished.