• Applied Biological Chemistry
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• 제21권1호
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• pp.51-57
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• 1978

3종(種)의 가지과(科) 식물중(植物中)의 sterol조성(組成)을 TLC, GLC 및 GLC-MS에 의(依)해서 분석(分析)하여 4-desmethylsterol fraction에서 7종(種), 4-monomethylsterol fraction에서 9종(種), 그리고 4.4-dimethylsterol fraction에서는 8종(種) 모두 24종(種) sterol을 동정(同定)하였고, 이들 sterol들이 식물체내(植物體內)에서 어떤 생합성경로(生合成經路)를 거치는가를 검토(檢討)하였다.

• 생약학회지
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• 제21권4호
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• pp.307-316
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• 1990

This study was undertaken to test the effects of Daturae Flos(DF) and Daturae Semen(DS) on the cellular and humoral immune responses, and the functions of the cells involved in immunoinflammation. Both extracts decreased the activity of superoxide dismutase, and the decrease was greater in the mouse group which was treated with DS. Both extracts decreased the phagocytic activity as measured by assessing the number of the latex particle within the phagocyte after incubation of peritoneal macrophages with fluorochrome-labelled latex particle and decreased natural killer cell activity as measured by enumerating the viable YAC-1 cells after treatment of target cells with splenic natural killer cells. Both extracts also decreased the cell-mediated immunity in vivo as assessed by measuring the ear thickness after sensitization and challenge with dinitrofluorobenzene, however, had no effects on the humoral immune responses as measured by checking hemolysin and hemagglutinin titers after immunization with sheep red blood cells(SRBC). Extracts of Semen caused decrease in the number of rosette forming cells between the splenic cells and SRBC. The results of this study suggested that both Daturae extracts could depress the immunoinflammation by affecting the various cell types involved in inflammation.