• Animal Bioscience
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• v.36 no.12
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• pp.1796-1805
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• 2023

Objective: This study aims to identify heat shock protein70-2 (HSP70-2) and protamine-1 (PRM1) mRNA and protein in Madura bull sperm and demonstrate their relation as bull fertility biomarkers. Methods: The Madura bull fertility rates were grouped based on the percentage of first service conception rate (%FSCR) as high fertility (HF) (79.04%; n = 4), and low fertility (LF) (65.84%; n = 4). mRNA of HSP70-2 and PRM1 with peptidylprolyl isomerase A (PPIA) as a housekeeping gene were determined by quantitative real-time polymerase chain reaction, while enzyme-linked immunoassay was used to measure protein abundance. In the post-thawed semen samples, sperm motility, viability, acrosome integrity, and sperm DNA fragmentation index were analyzed. Data analysis was performed on the measured parameters of semen quality, relative mRNA expression, and protein abundance of HSP70-2 and PRM1, among the bulls with various fertility levels (HF and LF) in a one-way analysis of variance analysis. The Pearson correlation was used to analyze the relationship between semen quality, mRNA, proteins, and fertility rate. Results: Relative mRNA expression and protein abundance of HSP70-2 and PRM1 were detected and were found to be highly expressed in bulls with HF (p<0.05) and were associated with several parameters of semen quality. Conclusion: HSP70-2 and PRM1 mRNA and protein molecules have great potential to serve as molecular markers for determining bull fertility.

• Journal of the Korea Institute of Building Construction
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• v.23 no.6
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• pp.773-784
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• 2023

Since 2007, the government has been actively working to enhance the quality of public buildings, as evidenced by initiatives like the "National Basic Architecture Plan" and, since 2014, the "Building Service Industry Promotion Act." Despite these efforts, educational facilities continue to experience more frequent defects compared to large-scale apartment constructions. This study aims to analyze the primary causes of crack formation in educational facilities, employing the 2×2 MATRIX and IPA techniques to develop efficient crack prediction models. The research includes a review of relevant literature and an analysis of data from the Office of Education spanning 2019 to 2021 to pinpoint significant defects. Subsequently, 15 factors related to crack defects were identified through surveys and expert consultations. The 2×2 Matrix analysis of these factors highlighted the challenges in work processes and the effectiveness of preventative measures for crack formation, focusing on key areas for improvement. The findings from this study are anticipated to significantly contribute to the prevention and management of structural cracks in educational facilities, ensuring their long-term integrity.

• Journal of the Korea Institute of Building Construction
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• v.23 no.6
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• pp.797-807
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• 2023

This research aims to investigate the alterations in typhoon patterns attributable to climate change and to quantitatively assess the risk of damage to residential structures. The increasing prevalence of climate anomalies and severe weather events, a consequence of global warming, is causing escalating damage globally. Notably, numerous countries are facing substantial devastation due to shifts in typhoon trajectories. Despite this, there exists a gap in empirical research quantifying the impact of these changes on building integrity and the associated risk alterations driven by climate change. In addressing this gap, our study analyzes the frequency and intensity of typhoons impacting Korea, examining the evolution of these meteorological phenomena. Furthermore, we employ the Korean Typhoon Vulnerability Function for residential facilities to quantify the altered risk posed by these changing patterns. The outcomes of this study provide the private sector with essential data to formulate diverse scenarios and business strategies in response to the escalating risks of typhoon-related damage. Additionally, it equips governmental bodies with the necessary insights to develop comprehensive risk management strategies to mitigate the effects of future typhoons.

• Journal of Industrial Convergence
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• v.22 no.4
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• pp.65-73
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• 2024

The purpose of this study was to identify the effect of job resources of hospital workers on presenteeism and to verify the mediating effect of job embeddedness based on this. Participants included 301 hospital workers form hospitals located in B city. Date was collected form July 10 to August 10, 2023. The collected data were analyzed by frequency analysis, descriptive statistics, Pearson's correlation coefficient, Baron and Kenny's three-step hierarchical regression and Sovel's test method using the SPSS 26.0 program. In this study, it was found that there was a correlation between job resources, job embeddedness and presenteeism of hospital workers, job resources and job embeddedness influenced negatively on presenteeism, and it was confirmed that job embeddedness partially mediated in the relationship between job resources and presenteeism. Based on this, in order to reduce presenteeism of hospital workers. it was suggested to improve job integrity by providing sufficient job resources institutionally an administratively and providing continuous educational opportunities.

• Transactions of the Korean hydrogen and new energy society
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• v.35 no.2
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• pp.195-204
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• 2024

The study involves a finite element analysis to evaluate the structural integrity of the neck mount block for a type 4 hydrogen storage vessel, with the aim of enhancing its strength and rigidity. The existing neck mount block consists of a fixed part and a sliding part, each comprising a body block for load support, a screw part for neck boss fixation, and bolts. To analyze the vulnerabilities of the neck mount block under bolt fastening and load conditions relative to vehicle travel directions, a structural analysis process was developed. Comparative analysis between the enhanced design and the existing model was performed, resulting in improved strength and rigidity. The objective is to provide guidance for the current product development and to offer fundamental data for the design and structural analysis of future development projects.

• Journal of the Korea Society of Computer and Information
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• v.29 no.1
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• pp.121-130
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• 2024

In this paper, we propose an installation approach for Naval Combat Management System(CMS) software that identifies potential data anomalies during installation. With the popularization of wireless communication methods, such as Low Earth Orbit(LEO) satellite communications, various utilization methods using wireless networks are being discussed in CMS. One of these methods includes the use of wireless network communications for installation, which is expected to enhance the real-time performance of the CMS. However, wireless networks are relatively more vulnerable to security threats compared to wired networks, necessitating additional security measures. This paper presents a method where files are transmitted to multiple nodes using encryption, and after the installation of the files, a validity check is performed to determine if there has been any tampering or alteration during transmission, ensuring proper installation. The feasibility of applying the proposed method to Naval Combat Systems is demonstrated by evaluating transmission performance, security, and stability, and based on these evaluations, results sufficient for application to CMS have been derived.

• Journal of Positioning, Navigation, and Timing
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• v.13 no.2
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• pp.189-197
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• 2024

Galileo is a European Global Navigation Satellite System (GNSS) that has offered the Galileo Open Service since 2016. Consequently, the standardization of GNSS augmentation systems, such as Satellite Based Augmentation System (SBAS), Ground Based Augmentation System (GBAS), and Aircraft Based Augmentation System (ABAS) for Galileo signals, is ongoing. In 2023, the European Union Space Programme Agency (EUSPA) released prior probabilities of a satellite fault and a constellation fault for Galileo, which are 3×10^-5 and 2×10^-4 per hour, respectively. In particular, the prior probability of a Galileo constellation fault is significantly higher than that for the GPS constellation fault, which is defined as 1×10^-8 per hour. This raised concerns about its potential impact on GBAS integrity monitoring. According to the Global Positioning System (GPS) Standard Positioning Service Performance Standard (SPS PS), a constellation fault is classified as a wide fault. A wide fault refers to a fault that affects more than two satellites due to a common cause. Such a fault can be caused by a failure in the Earth Orientation Parameter (EOP). The EOP is used when transforming the inertial axis, on which the orbit determination is based, to Earth Centered Earth Fixed (ECEF) axis, accounting for the irregularities in the rotation of the Earth. Therefore, a faulty EOP can introduce errors when computing a satellite position with respect to the ECEF axis. In GNSS, the ephemeris parameters are estimated based on the positions of satellites and are transmitted to navigation satellites. Subsequently, these ephemeris parameters are broadcasted via the navigation message to users. Therefore, a faulty EOP results in erroneous broadcast ephemeris data. In this paper, we assess the conventional ephemeris fault detection monitor currently employed in GBAS for wide faults, as current GBAS considers only single failure cases. In addition to the existing requirements defined in the standards on the Probability of Missed Detection (PMD), we derive a new PMD requirement tailored for a wide fault. The compliance of the current ephemeris monitor to the derived requirement is evaluated through a simulation. Our findings confirm that the conventional monitor meets the requirement even for wide fault scenarios.

• Journal of Pharmacopuncture
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• v.27 no.2
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• pp.131-141
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• 2024

Objectives: Polycystic ovary syndrome (PCOS) is one of the most common disorders and it shows up to 20% prevalence in reproductive-aged women populations, but no cures are available to date. We aimed to investigate the protective effects of Changbudodam-tang (CBD) on cell death signaling pathways, inflammation, and oxidative stress observed in Bone-Marrow derived human mesenchymal stem cell (BM-hMSC) by means of PCOS therapeutics in the future. Methods: BM-hMSCs were applied with cell deaths and injuries. Apoptosis and pyroptosis signals were quenched with their related signaling pathways using quantitative PCR, Western blot, and fluorescence image analysis. Results: Our data clearly displayed hydrogen peroxide- and nigericin-treated cell death signaling pathways via regulations of mitochondrial integrity and interleukin (IL)-1β at the cellular levels (p < 0.01 or 0.001). We further observed that pre-treatment with CBD showed protective effects against oxidative stress by enhancement of antioxidant components at the cellular level, with respect to both protein and mRNA expression levels (p < 0.05, 0.01 or 0.001). The mechanisms of CBD were examined by Western blot analysis, and it showed anti-cell death, anti-inflammatory, and antioxidant effects via normalizations of the Jun N-terminal kinase/mitogen-activated protein kinase kinase 7/c-Jun signaling pathways. Conclusion: This study confirmed the pharmacological properties of CBD by regulation of cellular oxidation and the inflammation-provoked cell death condition of BM-hMSCs, which is mediated by the MKK7/JNK/c-Jun signaling pathway.

• Journal of Advanced Navigation Technology
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• v.28 no.1
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• pp.1-14
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• 2024

Global navigation satellite system (GNSS) providing position, navigation and timing (PNT) services consist of satellite, ground, and user systems. Monitoring stations, a key element of the ground segment, play a crucial role in continuously collecting satellite navigation signals for service provision and fault detection. These stations detect anomalies such as threats to the signal-in-space (SIS) of satellites, receiver issues, and local threats. They deliver received data and detection results to the master station. This paper introduces the main monitoring algorithms and measurement pre-processing processes for quality assessment and fault detection of received satellite signals in current satellite navigation system monitoring stations. Furthermore, it proposes a strategy for the development of components, architecture, and algorithms for the new regional navigation satellite system (RNSS) monitoring stations.

• Clinical Nutrition Research
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• v.12 no.2
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• pp.116-125
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• 2023

The present study sought to examine the association between an infant's anthropometric outcomes with maternal Dietary Inflammatory Index (DII) and Alternate Healthy Eating Index for Pregnancy (AHEI-P) scores during the third trimester of pregnancy. This prospective cohort study was applying 130 pregnant women, at the pregnancy training center in west Tehran, Iran (November 2020 to July 2021). The maternal dietary intake, and body mass index (BMI), and social economic level were evaluated. The data about birth weight, birth height, head circumference, and, gestational age at birth were extracted from each child's health records. The ultimate sample included 122 (93.8%) pairs of women/newborn children. The participants, mean age was 28.13 ± 4.66 years with gestational age between 28 to 40 weeks and the mean of BMI was 24.62 ± 3.51. Our outcomes, after adjustment for confounding factors, suggested that those newborn infants in the highest quartile of maternal DII score had a significantly lower weight (p < 0.001) and height (p = 0.05), in comparison to those in the lowest quartile, but not head circumference (p = 0.18). Moreover, after adjustment for confounding factors, results suggested that those newborn infants in the First quartile of maternal AHEI-P score had a significantly lower weight (p = 0.018) and, in comparison to those in the higher quartile. It appears that newborn infants with lower maternal DII and higher AHEI-P scores may have a better anthropometric outcome. Further longitudinal and in-depth qualitative and quantitative studies, with a longer-term follow-up, is warranted to support the integrity of our outcomes.