• Archives of Pharmacal Research
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• v.29 no.6
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• pp.508-513
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• 2006

The effect of acteoside, a phenylpropanoid glycoside isolated from Clerodendron trichotomum Thunberg, on histamine and arachidonic acid release was investigated in RBL 2H3 cells. Histamine was dose-dependently released from RBL 2H3 cells by melittin, arachidonic acid and thapsigargin. In extracellular $Ca^{2+}-free$ solution, basal secretion of histamins increased by two fold. The response of histamine release to melittin and thapsigargin in $Ca^{2+}-free$ solution was significantly decreased, whereas the response to arachidonic acid was significantly increased as compared with those in normal solution. Acteoside inhibited histamine release induced by melittin, arachidonic acid and thapsigargin in a dose-dependent manner in the presence or absence of extracellular $Ca^{2+}$. However, the inhibitory activity of acteoside was more potent in normal solution than that in $Ca^{2+}-free$ solution. These data suggest that inhibitory mechanism of acteoside on histamine release may be related to extracellular $Ca^{2+}$. On the other hand, acteoside significantly inhibited arachidonic acid release and prostaglandin $E_2$ production Induced by $0.5\;{\mu}M$ melittin. It is possible that acteoside may be developed as an anti-inflammatory agent.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.8
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• pp.1903-1910
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• 2009

In this paper, we were researched decision problem called an optimal release policies after testing a software system in development phase and transferring it to the user. The applied model of release time exploited infinite failure non-homogeneous Poisson process This infinite failure non-homogeneous Poisson process is a model which reflects the possibility of introducing new faults when correcting or modifying the software. The failure life-cycle distribution used the Weibull distribution which has the efficient various property which has the place efficient quality. Thus, optimal software release policies which minimize a total average software cost of development and maintenance under the constraint of satisfying a software reliability requirement becomes an optimal release policies. In a numerical example, after trend test applied and estimated the parameters using maximum likelihood estimation of inter-failure time data, estimated software optimal release time.

• Asian Journal of Turfgrass Science
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• v.21 no.2
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• pp.177-182
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• 2007

When a football field is constructed using sand medium, the fertilizer management has to be adjusted because of the low nutrient holding capacity and higher leaching rate. The objective of this study was to test the effects of slow release fertilizers on Kentucky bluegrass (Poa pratensis L.) growth in simulated sport field rootzones with PVC pipe pots. Data of turfgrass color, uniformity, growth rate, biomass above ground, and the nitrate content in the leaching solution was collected at different growing stages and during four simulated rain fall periods. The result showed that the nutrient release rate of urea was the highest and that of controlled release nitrogen fertilizer was the lowest. Effects of the controlled release nitrogen fertilizer lasted 14 days more than other lawn fertilizers and 28 days longer than regular urea with acceptable quality levels of turf. The slow release fertilizer also restrained excessive growth of the grass, reduced the times of mowing. Slow release fertilizer used in this study reduced $NO_3$-N leaching by almost 50% at the beginning of turf establishment.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.26 no.2
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• pp.73-80
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• 2020

Background: This study examined the effects of myofascial release exercise using an inflatable compression therapy ball on spinal flexibility in adults to present basic data to improve spinal flexibility. Methods: The participants were assigned randomly to two groups: the myofascial release exercise group (MRE, n=60) and the stretching exercise group (SE, n=60). The MRE group performed myofascial release exercise for the erector spine muscles using an inflatable compression therapy ball. The SE group performed stretching exercises of the erector spine muscles. Each exercise was performed in 3 sets of 10 repetition daily for one week. Results: The within-group comparison revealed a statistically significant difference between the pre-intervention and post-intervention measurements in only MRE group (p<.05). On the other hand, the between-group comparison revealed the MRE group to show statistically significant improvement in spinal flexibility (p<.05). In effect size, the MRE group was -1.82 (95% CI= -2.24~-1.39), and the SE group was -.7 (95% CI= -1.15~-.41). Conclusion: Myofascial release exercise for the erector spine muscles using an inflatable compression therapy ball was more effective in improving spinal flexibility than stretching exercises for the erector spinae muscles. However, although myofascial release exercise using inflatable compression therapy ball is more effective than stretching exercise, it is insignificant, and research is also insignificant. It is believed that more diverse studies using props will be needed in the future.

• Korean Journal of Veterinary Research
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• v.38 no.4
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• pp.712-719
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• 1998

Thyroid function is mainly regulated through cAMP and phophatidylinositol, and it is well known that TSH-stimulated thyroxine ($T_4$) release is inhibited by catecholamine from mouse thyroids via the ${\alpha}_1$-adrenoceptor stimulation. Previous study has established that the inhibition of $T_4$ release by ${\alpha}_1$-adrenoceptor stimulation results in activated protein kinase C (PKC). The purpose of this study was to determine if ion transport systems are involved in the inhibition of $T_4$ release elicited by ${\alpha}_1$-adrenergic agonist in mouse thyroids. TSH-, IBMX- and cAMP analogue-stimulated $T_4$ release were significantly inhibited by methoxamine, R59022 (diacylglycerol kinase inhibitor), and MDL (adenylate cyclase inhibitor). TSH-stimulated $T_4$ release could be inhibited by Bay K 8644 and cyclopiazoic acid, but not by verapamil and tetrodotoxin. The addition of nifedipine ($Ca^{2+}$ channel blocker), tetrodotoxin and lidocaine ($Na^+$ channel blockers), but not amiloride (EIPA) and ryanodine, completely blocked the inhibitory effects of methoxamine on $T_4$ release. TSH-stimulated $T_4$ release was also inhibited by benzamil ($Na^+-Ca^{2+}$ exchange inhibitor). TSH-, IBMX- and cAMP-stimulated $T_4$ release were inhibited by methoxamine or R59022, these effects were reversed by nifedipine. but not by verapamil. Furthermore, nifedipine reversed the inhibitory effects of benzamil and R59022 on TSH-stimulated $T_4$ release. These data suggest that the observed ${\alpha}_1$-adrenoceptor-mediated inhibition of $T_4$ release in mouse thyroids is the result of an increase in intracellular $Na^+$ or $Ca^{2+}$ effected via activation of fast $Na^+$ or nifedipine-sensitive $Ca^{2+}$ channels, and that $Na^+-Ca^{2+}$ exchange may play an important role in reducing thyroid hormone by increasing intracellular $Ca^{2+}$.

• Clinics in Shoulder and Elbow
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• v.20 no.3
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• pp.117-125
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• 2017

Background: To compare the clinical outcomes of arthroscopic capsular release in patients with and without inferior capsular release for shoulder stiffness. Methods: Between January 2010 and December 2015, 39 patients who underwent arthroscopic capsular release for shoulder stiffness were enrolled and randomized into two groups. In group I, 19 patients underwent arthroscopic capsular release of the rotator interval and anterior capsule. In group II, 20 patients underwent arthroscopic capsular release of the anterior to inferior capsule, including the rotator interval. The American Shoulder and Elbow Surgeons score, Constant scoring system, Simple Shoulder Test, visual analogue scale for pain, and range of motion (ROM) were used for evaluation before surgery, at 3, 6, and 12 months after surgery and on the last follow-up. Results: Preoperative demographic data revealed no significant differences (p>0.05). The average follow-up was 16.07 months. Both groups showed significantly increased ROM at the last follow-up compared with preoperative (p<0.05). At the last follow-up, no statistical differences were found (p>0.05) between groups I and II in functional scores and ROM (forward flexion, p=0.91; side external rotation, p=0.17; abduction external rotation, p=0.72; internal rotation, p=0.61). But we found that group II gained more flexion compared to group I at 3 months and 6 months (p<0.05) after the surgery. Conclusions: Both techniques of capsular release are effective for stiffness shoulder. However, the extended inferior capsular release shows superiority in forward flexion over anterior capsular release alone during 6 months of follows-up (level of evidence: Level I, therapeutic randomized controlled trial).

• Proceedings of the IEEK Conference
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• 1998.10a
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• pp.221-224
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• 1998

Software release over the network is the most efficacious way of software update. Software release of electronic switching system, considering its environments, is the typical case that is in need of adopting the method. The media of transferring software and data of TDX-10A electronic switching system are magnetic tapes containing them, so the MT must be delivered between remotely placed office and package generation system. SMART-10A system provides the file tranfer on the data network between TDX-10A and the package generation system and ability of remote application of new software. This paper shows the implementation of file transfer between TDX-10A and computer system connected by data networks, status handling for duplicated system, and monitor process design with IPC on UNIX system.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.7 no.2
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• pp.16-22
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• 2008

This study was analyzed dynamically by finite element method about the results of experiments which materials were applied by dynamic load. And they were compared with each other as the simulation data applied onto dynamic impact velocities of 6.4, 16.7 and 18.47m/s. The crack energy release rate, von-Mises stress and the displacement according to the load applied by block were calculated numerically by computer. As the numerical simulation data of specimen analyzed in this study approached the experimental data, the inspection of this specimen model suggested in this paper could be reasonable for the numerical simulation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.8 no.3
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• pp.421-426
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• 2007

This study was analyzed dynamically by finite element method about the results of experiments which the double cantilever beam specimens with two kinds of materials were applied by impact load. And they were compared with each other as the simulation data applied onto impact velocities of 6.4 and 18.47 m/s. The crack energy release rate, force and displacement of block were calculated numerically by computer. As the numerical simulation data of specimen analyzed in this study approached the experimental data, the inspection of this specimen model suggested in this paper could be reasonable for the numerical simulation.

• Magazine of the Korean Society of Agricultural Engineers
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• v.30 no.1
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• pp.50-62
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• 1988

This study refers to the development of a hydrologic model simulating daily inflow and release rates for irrigation reservoirs. A daily - based model is needed for adequate operation of an irrigation reservoir sufficing the water demand for paddy fields which is closely related to meteorological conditions. Inflow rates to a reservoir need to be accurately described, which may be simulated using a hydrologic model from daily rainfall data. And the objective of this paper is to develop, test, and apply a hydrologic model for daily runoff simmulation. A well - known tank model was selected and modified to simulate daily inflow rates. The model parameters were calibrated using observed runoff data from twelve watersheds, Relationships between the parameters and the watershed characteristics were derived by a multiple regression analysis. The simulation results were in agreement with the data. The inflow model was found to simulate low flow conditions more accurately than high flow conditions, which may be adequate for water resources utilization.