• 제목/요약/키워드: Data Heterogeneity

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다낭성 난소 증후군의 침치료 연구에 관한 체계적 문헌고찰 (Recent Acupuncture Therapy for Polycystic Ovary Syndromes : Systematic Review)

  • 김세화;황덕상;이진무;이경섭;이창훈;장준복
    • 대한한방부인과학회지
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    • 제27권2호
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    • pp.71-82
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    • 2014
  • Objectives: The purpose of this systematic review was to overview and evaluate the efficacy of acupuncture treatment for women with polycystic ovary syndrome (PCOS). Methods: Relevant randomized controlled studies (RCTs) were identified by database searches in MEDLINE, EMBASE, and CENTRAL, up to Dec 2013, and by additional hand searches. Data were extracted regarding anovulation, hyperandrogenism, obesity indices. Meta-analyses were separatedly conducted for the symptoms of PCOS. The risk of bias was assessed. Results: Three studies which were included for analysis, but they showed severly heterogeneity therefore meta-analysis could not be performed. Outcomes for evaluating the efficacy of acupuncture treatment for PCOS were anovulation index (menstrual frequency), hyperandrogenism index (free testosterone) and obesity index (body-mass index). For menstrual frequency, acupuncture treatment consistently suggested an interventional benefit. Although other outcomes did not suggest any enough relevant evidence to interventional benefit for acupuncture treatment. Conclusions: Acupuncture treatment appeared to improve menstrual frequency in PCOS patients. Since a limited number of RCTs were available in the current literature and those studies were also clinically heterogeneous, further research is needed to gather evidence to support acupuncture therapy in PCOS.

Risk Factors of Breast Cancer in the Eastern Mediterranean Region: A Systematic Review and Meta-Analysis

  • Namiranian, Nasim;Moradi-Lakeh, Maziar;Razavi-Ratki, Seid Kazem;Doayie, Mahdyie;Nojomi, Marzieh
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권21호
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    • pp.9535-9541
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    • 2014
  • Background: Identifying risk factors of breast cancer is a key point for preventive strategies to reduce the incidence. The aim of current study was to determine most important risk factors for breast cancer in the Eastern Mediterranean Region (EMR) using a systematic review. Materials and Methods: PubMed, Scopus, Web of Science till August 24, 2012 and the reference lists of all included studies were searched. Analytic studies which had reported odds ratios (OR), relative risk (RR) or required data to calculate them were included. A total of 343 studies were critically appraised and finally 30 studies were meta-analyzed. Heterogeneity between the studies was assessed by $I^2$ and Cochran's Q. Egger's test was used to assess publication bias. Results: Twenty five casecontrol studies, one nested case-control and four cohort studies were included. The largest ORs were obtained for history of no live birth (2.25; 95%CI: 1.58-3.18), body mass index (BMI) more than 30 (2.21; 95%CI: 1.71-2.36), age at first pregnancy more than 30 years old (1.52; 95%CI: 1.30-1.77) and meat consumption more than three times per week (1.39; 95%CI: 1.03-1.87). The other important predictors were higher education and smoking as risk factors, physical activity and ovulatory stimulating medication as protective factors. Conclusions: The most important predictors of breast cancer in EMR were history of no live birth, BMI more than 30, age at first pregnancy more than 30 years old, physical inactivity and smoking. Almost all these risk factors are consistent with known risk factors for this cancer in other parts of the world.

Factors Affecting Scaling Experiences of Adolescent Children from Multicultural and Native Families

  • Ahn, Eunsuk;Yang, Jin-Young;Kim, Ki-Eun
    • 치위생과학회지
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    • 제20권2호
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    • pp.89-96
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    • 2020
  • Background: Multicultural families are constantly on the rise as marriage migrants and foreign workers increase. Multicultural families appear to record poor health levels compared to native families. As health is a social issue, children of surviving generations of multicultural families are also a growing interest. This study was conducted to confirm the effect of multicultural families and parents' educational level on the scaling experience of children. Methods: For this study, the 2016~2018 Korea Youth Risk Behavior Web-based Survey data were used. In order to make the two groups of adolescents belonging to multicultural and native families similar, a total of 5,362 people were included in the survey, consisting of 2,681 individuals each from multicultural and native families using the propensity score matching method. Logistic analysis was performed to identify factors influencing the scaling experience of adolescent children. Results: The results confirm that, even after controlling for factors such as parents' educational level, household income, and children's oral health behavior, parents' nationality appeared to have a statistically significant effect on their children's scaling experience. In addition, it was confirmed that the experience of oral health education had a significant effect. Conclusion: Cultural heterogeneity and the lack of adequate language ability of immigrants affects health behavior and medical accessibility. Therefore, children from multicultural families are more likely to be exposed to unhealthy environments compared to the children of native Korean families. Based on an understanding of the socioeconomic multicultural background of individuals, education and public policy should be prepared to improve the awareness for the need for preventive oral health and provide unhindered accessibility to dental services.

OECD 15개국 중고령 남성의 취업률 결정요인 (The Factors Determining on the Employment Rate of Men Aged 55~64 in 15 OECD Countries)

  • 지은정
    • 한국사회복지학
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    • 제63권2호
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    • pp.233-260
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    • 2011
  • 본 연구는 1980~2005년 OECD 15개국 중고령 남성의 취업률 추이 및 취업률 결정요인을 분석하여 중고령 남성의 노동시장참여를 지원할 수 있는 방안을 살펴보고자 한다. 자료는 OECD, ILO, LIS이다. 분석은 노동시장참여의 상태의존성과 패널개체의 이질성을 반영한 동적패널모형으로서, 도구변수를 사용한 Arellano and Bonds(1981)의 차분 GMM으로 하였다. 분석결과, 55~64세 남성의 취업률은 1990년대 중반까지 감소하였으나, 그 이후 증가하고 있다. 둘째, 1980~2005년 기간동안 중고령 남성의 취업률은 상태의존성이 강하게 작용하였고, 정적인 기간효과가 나타났다. 공적 연금의 유인효과는 크게 나타나지 않았고, 노동시장의 배출요인이 부적인 영향을 미쳤다. 셋째, 1996~2005년은 노동시장위험완화요인인 임시직 비율이 중고령 남성의 취업률에 기여하였고, 빈곤이 노동의 메커니즘으로 나타났다.

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Chondroid Syringoma on Face

  • Min, Kyung Hee;Byun, Jin Hwan;Lim, Jung Soo;Lee, Hye Kyung;Lee, Won Mi;Joo, Jong Eun
    • 대한두개안면성형외과학회지
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    • 제17권3호
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    • pp.173-175
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    • 2016
  • Chondroid syringoma is a rare mixed tumor of the skin which is composed of both mesenchymal and epithelial cells. Its incidence at less than 0.1% and is frequently located on the head and neck. Chondroid syringoma is easily confused with epidermal cysts. Since malignant forms of chondroid syringoma have been reported, accurate and timely diagnosis is important for proper management. We report clinical and histological features of chondroid syringoma in 5 patients treated at our institution. In most of the cases, chondroid syringoma presented as a round, firm, nodular or cystic lesion that had well marginated heterogeneity in sonography. Clinically, all of the lesions were removed by simple excision. Microscopically, all five tumors were well circumscribed and consisted of epithelial, myoepithelial, and stromal components. The epithelial component formed tubules lined by one or more rows of eosinophilic epithelial cells. The outer layer of tubules appeared to be flattened myoepithelial cells. The stroma is myxoid and contained spindle shaped myoepithelial cells. We expect that the clinical, sonographic, and histological data from our report may help clinicians who are confronted with various kinds of analogous facial lesions to decide the most proper management for their patients.

수입관세 인하가 기업 생산성에 미치는 효과 분석 (Tariff Reduction and Within-Plant Productivity: Micro-evidence from Korean Manufacturing)

  • 이시욱
    • KDI Journal of Economic Policy
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    • 제29권3호
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    • pp.75-109
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    • 2007
  • 본 연구는 1993~2003년 기간 중 통계청의 "광공업통계조사보고서"의 원자료에 포함되어 있는 개별 사업체 수준의 패널자료를 이용하여 수입관세의 변화가 우리나라 개별 사업체의 생산성에 미치는 영향을 실증분석하고 있다. 분석 결과에 따르면, 첫째 분석기간 중 우리나라 제조업 전반의 생산성 변화는 산업 내 혹은 산업간 자원이동에 기인했다기보다는 개별 사업체 내부의 생산성 변화에 의해 결정된 것으로 나타났다. 둘째, 수입관세장벽이 낮을수록 개별 사업체의 총요소생산성 증가율이 높은 것으로 나타났다. 이는 관세 장벽의 철폐를 통한 수입시장의 개방이 국내시장에서의 경쟁을 촉진함으로써 개별 기업으로 하여금 생산 경영의 비효율성을 줄이고 기업의 혁신역량을 배양하는 유인으로 작용한 데 기인하는 것으로 사료된다. 셋째, 연도별로는 관세율 인하 후 첫 번째 연도의 생산성 증가율이 가장 높은 것으로 나타나 사업체들이 비교적 짧은 기간 내에 관세 변화에 적응하는 것으로 나타났다. 반면, 고용의 경우에는 관세율 인하 후 차기연도 내에는 통계적으로 유의한 수준의 고용 변화가 감지되지 않지만, 이후 고용증대효과가 서서히 나타나는 것으로 분석되었다.

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골관절염 치료제 히알우론산 임상연구결과의 Systemic Review (Systemic Review of Hyaluronate for the Treatment of Osteoarthritis)

  • 방준석
    • 한국임상약학회지
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    • 제17권1호
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    • pp.38-45
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    • 2007
  • Background: The multitude of the therapeutic usefulness of intra-articular injection of hyaluronate on oateoarthritis of the knee is still in question. The objective of this systemic review was to elucidate both the therapeutic efficacy and the safety of intra-articular administration of hyaluronic acid for degenerative osteoarthritis of the knee joints. Methods: I searched MEDLINE and Korea Medical Database (KMbase) from January 1990 to April 2007 using a combination search terms for knee osteoarthritis and hyaluronic acid and a filter for randomized controlled trials. I extracted data on pain at rest, and during or just after movement, on joint function, and on adverse events. Results: Ten trials that reported usable quantitative information on any of the predefined end points were identified and included in the systemic review. Intra-articular injection of hyaluronic acid can decrease symptoms of osteoarthritis of the knee. The study revealed significant improvements in pain and functional outcomes with few adverse effects. However, there was significant between-study heterogeneity in the estimates of the efficacy of hyaluronic acid. Sub-group analysis showed that lower methodological quality such as a single-blind or single-center design resulted in higher estimates hyaluronic acid efficacy, and that patients older than sixty years of age and those with the most advanced radiographic stage of osteoarthritis were less likely to benefit from intra-articular injection of hyaluronic acid. Conclusion: According to the currently available evidence, intra-articular hyaluronic acid has been proven clinically effective for the patients bearing the knee osteoarthritis with NSAID-induced GI troubles or inapplicable to any surgery, and may be associated with lower risk of adverse events.

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웃음치료가 노인 우울에 미치는 효과에 관한 융합연구: 메타분석 (Convergence Study of Laughter Therapy's Effects on Depression among Older Adults in Korea: A Meta-Analysis)

  • 도은나;조선희;김선경
    • 한국융합학회논문지
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    • 제9권6호
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    • pp.347-355
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    • 2018
  • 본 연구는 우리나라 노인을 대상으로 시행된 웃음치료의 융합적 메타분석을 통해, 노인우울 감소 효과크기를 확인하고, 노인의 우울감소를 위한 웃음치료의 중재특성과 경향을 파악하기 위하여 실시된 융합적 연구이다. 10개의 데이터베이스 검색을 통해 확인한 486개 문헌 중 선정기준에 부합하는 20문헌을 최종 선정하였다. SIGN의 도구를 이용하여 문헌의 질평가를 시행하였으며 CMA 3.0을 활용하여 자료를 분석하였다. 노인우울에 대한 웃음치료의 전체효과크기는 중간크기로 나타났으며 (SMD=-0.57, 95% CI: -0.70~-0.44, p<.001), 작은 크기의 이질성을 보였다($I^2=18%$). 하위그룹 분석에서 재가노인, 통합군, 4-6주 중재군, 집단중재군의 효과가 더 컸다. 본 융합연구의 결과를 활용하여 효과적인 웃음치료 프로그램 구성을 도모할 수 있을 것이며, 추후 노인요양시설 노인을 대상으로 한 반복연구와 무작위배정 실험연구가 더 필요하다.

An Analysis on Landscape Structure and Biodiversity of the Bokha Stream as a Model to Restore the Degraded Urban Stream

  • Lee, Chang-Seok;Moon, Jeong-Suk;Woo, Hyo-Seop;Ahn, Hong-Gyu;Cho, Gang-Hyun;Bae, Yang-Seop;Byun, Hwa-Geun
    • Journal of Ecology and Environment
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    • 제29권2호
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    • pp.113-124
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    • 2006
  • Landscape structure, habitat types, vegetation structure and biodiversity in the Bokha stream chosen as a reference stream were investigated to get ecological information necessary for restoration of urban stream degraded by excessive artificial interference. Landscape structure showed a slight change between before and after flooding. Habitat types of nine sorts were identified based on ecological information obtained from field survey such as micro-topography, hydrological characteristics, disturbance regime, and so on. Each habitat holds specific organisms to each site. Consequently, the number of plant communities, and species of benthos and fish increased as the kinds of habitat type increase. Ordination of habitat types based on vegetation, benthos, and fish data reorganized them into three groups of pool types of two kinds depending on whether they are connected to the water course or not and riffle one. Vegetation showed different stratification and species composition depending on topographical position in relation to disturbance cycle. Based on the results from this study, relationship between environmental heterogeneity and biodiversity was discussed and a restoration plan was suggested in a viewpoint of vegetation.

양식업의 양식방법별 어종별 생산효율성 비교분석에 관한 연구 (The Study on the Comparative Analysis of the Aquaculture Production Efficiency Regarding Methods and Species)

  • 박철형
    • 수산경영론집
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    • 제43권2호
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    • pp.79-94
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    • 2012
  • The purpose of this study is to investigate the production efficiencies of the Korean aquaculture fishery with respect to species and methods using a Data Envelopment Analysis. The study extracted the 8 fishes in each of the sea cage culture, aquarium basin, and enclosed aquaculture for the analytical purposes. First, the study estimated the technical, pure technical, and scale efficiencies of the total of 24 aquaculture fishes based on the traditional DEA under the assumptions of both CRS and VRS. 2 fishes were identified as the efficient DMUs under the CCR-model, and 6 fishes under the BCC-model. Second, we tested to see if there was any difference in production efficiencies regarding those three different methods of aquaculture. we could not find any evidence of the differences in efficiency using a rank sum test based on the traditional DEA. However, we could do find that the pure technical efficiency in the sea cage culture was lower than others at 1% level of significance and the pure technical efficiency in enclosed aquaculture was also lower than others at 5% level of significance using Bilateral-DEA, which could explicitly consider the heterogeneity in the 3 production methods of aquaculture. Finally, the study obtained the 95% confidence intervals of the efficiency scores for the 24 fishes under our study using the smoothed bootstraping method in the process of the re-sampling in cooperation with both a kernel density estimation and a reflection method. At the same time, we could estimate the bias-corrected efficiency scores while the traditionally estimated efficiency scores suffered from the biases in the process of solving a linear programming with the deterministic nature of a production frontier. And hence, we could distinguish the differences in production efficiencies of the 8 fishes with respect to those 3 methods of aquaculture.