• Title/Summary/Keyword: Data Access Control

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Usability of DNA Sequence Data: from Taxonomy over Barcoding to Field Detection. A Case Study of Oomycete Pathogens

  • Choi, Young-Joon;Thines, Marco
    • 한국균학회소식:학술대회논문집
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    • 2015.11a
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    • pp.41-41
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    • 2015
  • Oomycetes belong to the kingdom Straminipila, a remarkably diverse group which includes brown algae and planktonic diatoms, although they have previously been classified under the kingdom Fungi. These organisms have evolved both saprophytic and pathogenic lifestyles, and more than 60% of the known species are pathogens on plants, the majority of which are classified into the order Peronosporales (includes downy mildews, Phytophthora, and Pythium). Recent phylogenetic investigations based on DNA sequences have revealed that the diversity of oomycetes has been largely underestimated. Although morphology is the most valuable criterion for their identification and diversity, morphological species identification is time-consuming and in some groups very difficult, especially for non-taxonomists. DNA barcoding is a fast and reliable tool for identification of species, enabling us to unravel the diversity and distribution of oomycetes. Accurate species determination of plant pathogens is a prerequisite for their control and quarantine, and further for assessing their potential threat to crops. The mitochondrial cox2 gene has been widely used for identification, taxonomy and phylogeny of various oomycete groups. However, recently the cox1 gene was proposed as a DNA barcode marker instead, together with ITS rDNA. To determine which out of cox1 or cox2 is best suited as universal oomycete barcode, we compared these two genes in terms of (1) PCR efficiency for 31 representative genera, as well as for historic herbarium specimens, and (2) in terms of sequence polymorphism, intra- and interspecific divergence. The primer sets for cox2 successfully amplified all oomycete genera tested, while cox1 failed to amplify three genera. In addition, cox2 exhibited higher PCR efficiency for historic herbarium specimens, providing easier access to barcoding type material. In addition, cox2 yielded higher species identification success, with higher interspecific and lower intraspecific divergences than cox1. Therefore, cox2 is suggested as a partner DNA barcode along with ITS rDNA instead of cox1. Including the two barcoding markers, ITS rDNA and cox2 mtDNA, the multi-locus phylogenetic analyses were performed to resolve two complex clades, Bremia lactucae (lettuce downy mildew) and Peronospora effuse (spinach downy mildew) at the species level and to infer evolutionary relationships within them. The approaches discriminated all currently accepted species and revealed several previously unrecognized lineages, which are specific to a host genus or species. The sequence polymorphisms were useful to develop a real-time quantitative PCR (qPCR) assay for detection of airborne inoculum of B. lactucae and P. effusa. Specificity tests revealed that the qPCR assay is specific for detection of each species. This assay is sensitive, enabling detection of very low levels of inoculum that may be present in the field. Early detection of the pathogen, coupled with knowledge of other factors that favor downy mildew outbreaks, may enable disease forecasting for judicious timing of fungicide applications.

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Effectiveness of Intervention for the Caregivers of Long-term Care Elderly (장기요양보호대상노인 가족부양자에 대한 개입의 효과성)

  • Kim, Soo-Young
    • Korean Journal of Social Welfare
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    • v.56 no.2
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    • pp.285-310
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    • 2004
  • The major purpose of this study is to examine effectiveness of an intervention program which aims at education/training caregivers of the dementia and/or stroke elderly. This program was conducted at group level. Participants of this program were the primary caregivers who have taken care of the elderly with dementia and/or stroke. To test the effectiveness of the caregiver education/training program, this study employed an quasi-experimental design: to compare pretest score with posttest ones for the same participants. Total forty two primary caregivers have completed the program. Seventeen caregivers were in experimental group, whereas twenty five ones belonged to control group. Our data suggest that, for the primary caregivers, subjective quality of life was more important than cargiving burden. Subjective quality of life among the caregivers significantly improved, after completing the program. This result suggests that a short-term intervention program at group level is not effective to reduce caregiving burden because an infra structure of community resources, to which the caregivers and their family access, did not remain at sufficient level. However, participants have showed improved mutual solidarity, and they have exposed to wider spectrum of a variety of information. As a result, they have perceived that the level of subjective quality of life has positively changed. Additional factors have influenced on determining the quality of life among the caregivers. The caregivers, whose demented elderly showed lower level of ADL and IADL, or who have experienced the short period of caregiving, were more likely to belong to higher level of quality of life. The quality of life among the caregivers were even more improved in the following group: being young, and highly educated, man. One of the contributions from this study is that we have found caregiver's characteristics, which need an intervention most. In addition, our study implies that specific contents of the caregivers' education/training program should be conducted based on each family's unique characteristics.

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A Study on Interconnectioned LAN of Token Ring Network (토큰링 네트워크가 상호 연결된 근거리 통신망에 관한 연구)

  • 이상훈;김경식;강준길
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.17 no.11
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    • pp.1206-1218
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    • 1992
  • Token ring systems which control to switch the data stream of networks by passing the token have been widely used to medium access controls in many ring or bus topology LANs. The system could be modeled for analysis as single-server-multi-queue system of the cyclic service method. These concepts could be expanded to multi-token ring systems interconnected with single ring consisting of bridges implemented simply to be stored and transmitted. In the proposal for the performance analysis of the interconnected token ring system, in has been assumed M/G/1 queueing model that frame arrivals are the Poisson process at each station queue and frame sizes are independently and identically distributed. And the average time delays were analyzed mathematically for arbitrary frame transferred from source station to destination area. The time delay of the frame transmission could be explained as the sum of the average time which the token passed from arbitrary position to source station, such as the waiting time in the source station transferring the previous arrival frames, and the propagation time from source station to interdestinated point. These delays were given as the sum of the duration from inner and outer bridge queues, the time delays from inner and outer bridge queues, and the time from outer bridge queue to destination station. These results were investigated by varing parameters effected to total time delays. In the results, those factors to be effected to dominant the total time delays were increased were in the cases of the high arrival rates and the high ration of destination of the other outerring. The system were shown the time delays increased exponentially in spite of the priority service policy. In order to decreasing the number of outerrings and increasing the number of nodes in backbone relatively, so the systems could be decreased the total delay in the interconnected token ring system.

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TradeB: A Blockchain-based Property Trade Service Using Trusted Brokers (TradeB: 신뢰성있는 중개인을 통한 블록체인 기반 재화 계약 서비스)

  • Yoon, Yeo-Guk;Eom, Hyun-Min;Lee, Myung-Joon
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.9 no.9
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    • pp.819-831
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    • 2019
  • The types of properties traded in modern times are rapidly increasing due to changes in consumption patterns. However, as the type of properties traded increases, estimation about the value of properties may become inaccurate. There is a problem that it is difficult for consumers to estimate the right value and the variety of trading forms makes it difficult to guarantee the reliability of value estimation As access to a variety of properties has expanded, these shortcomings are considered to be a factor that hinders the stability of the shared economic market. In this paper, to resolve this issue, we present a blockchain-based property contract service through a trusted broker. The developed service registers trusted brokers into smart contracts on the Ethereum blockchain and use them for the evaluation and contract process of properties. In addition, registered contents, proposals and contracts of properties are stored in the blockchain to ensure the reliability of the contract process. Every step of the contract process is stored in the smart contract, recorded in the transaction history of the blockchain, ensuring the reliability of the stored data. In addition, the entire process of registration, proposal, and contract is driven by smart contracts designed by state machine technology, enabling users to more securely control the contract process.

Interregional Variant Factor Analysis of Hypertension Treatment Rate in COVID-19 (코로나19에서 고혈압 치료율의 지역 간 변이요인 분석)

  • Park, Jong-Ho;Kim, Ji-Hye
    • Journal of Digital Convergence
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    • v.20 no.4
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    • pp.469-482
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    • 2022
  • The purpose of this study is to analyze regional variation factors of hypertension treatment rate in COVID-19 based on the analysis results based on ecological methodology. To this end, data suitable for ecological analysis were collected from the Korea Centers for Disease Control and Prevention's regional health statistics, local government COVID-19 confirmed cases, National Health Insurance Corporation, Health Insurance Review and Assessment Service's welfare statistics, and Korea Transport Institute's traffic access index. Descriptive statistics and correlation analysis were conducted using SPSS Statistics 23 for regional variation and related factors in hypertension treatment rate, and geographical weighted regression analysis was conducted using Arc GIS for regional variation factors. As a result of the study, the overall explanatory power of the calculated geo-weighted regression model was 27.6%, distributed from 23.1% to 33.4% by region. As factors affecting the treatment rate of hypertension, the higher the rate of basic living security medical benefits, diabetes treatment rate, and health institutions per 100,000 population, the higher the rate of hypertension treatment, the lower the number of COVID-19 confirmed patients, the lower the rate of physical activity, and the alcohol consumption. Percentage of alcohol consumption decreased due to COVID-19 pandemic. It was analyzed that the lower the ratio, the higher the treatment rate for hypertension. Based on these results, the analysis of regional variables in the treatment rate of hypertension in COVID-19 can be expected to be effective in managing the treatment rate of hypertension, and furthermore, it is expected to be used to establish community-centered health promotion policies.

A Study on Measurements of Autoignition and Activation Energy of Superabsorbent Polymers (고흡수성 중합체의 자연발화와 활성화에너지 측정에 관한 연구)

  • Jong-Man Heo;Jae-Wook Choi
    • Journal of the Society of Disaster Information
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    • v.19 no.2
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    • pp.292-304
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    • 2023
  • Purpose: This study was conducted to obtain experimental data for the establishment of preventive measures against fire, as large and small fire accidents occur at production and storage sites of superabsorbent polymers developed for the convenience of daily life. Method: The sample container was fixed at 0.2m in both length and width, and was shaped into a rectangular cuboid with heights of 3cm, 5cm, 7cm, and 14cm to access an infinite flat plane. The sample container was fixed in the center of a thermostatic bath that was heated to a predetermined temperature according to a preset temperature control program. If the central temperature of the sample rose more than 20℃ above the set temperature, it was determined to have 'ignited', and if it remained similar to the set temperature, it was determined to have 'unignited'. Result: The critical autoignition temperature was calculated to be 212.5℃ for a sample container with a height of 3cm, 202.5℃ for 5cm, 192.5℃ for 7cm, and 177.5℃ for 14cm. The ignition induction time to reach the highest temperature was approximately 42hours for 3cm, 91hours for 5cm, 151hours for 7cm, and 300hours for 14cm. Conclusion:① As the size of the sample container increased, the autoignition temperature decreased and the ignition induction time to reach the highest temperature increased. ② The apparent activation energy was calculated to be 39.30kcal/mol, with a correlation of 99.5%.

Technology Licensing Agreements from an Organizational Learning Perspective

  • Lee, JongKuk;Song, Sangyoung
    • Asia Marketing Journal
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    • v.15 no.3
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    • pp.79-95
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    • 2013
  • New product innovation is a process of embodying new knowledge in a product and technology licensing is getting popular as a means to innovations and introduction of new product to the market in today's competitive global market environment. Incumbents often rely on technology licensing to access new product opportunities created by other firms. Prior research has examined various aspects of technology licensing agreements such as specific contract terms of licensing agreements, e.g., distribution of control rights, exclusivity of licensing agreements, cross-licensing, and the scope of licensing agreements. This study aims to provide answers to an important, but under-researched question: why do some incumbents initiate more licensing agreement for exploratory learning while others do it for exploitative learning along the innovation process? We attempt to extend our knowledge of licensing agreements from an organizational learning perspective. Technology licensing as a specific form of interfirm linkages can be initiated with different learning objectives along the process of new product innovation. The exploratory stages of the innovation process such as discovery or research stages involve extensive searches to create new knowledge or capabilities, whereas the exploitative stages of the innovation process such as application or test stages near the commercialization are more focused on developing specific applications or improving their efficiency or reliability. Thus, different stages of the innovation process generate different types of learning and the resulting technological resources. We examine when incumbents as licensees initiate more licensing agreements for exploratory learning objectives and when more for exploitative learning objectives, focusing on two factors that may influence a firm's formation of exploratory and exploitative licensing agreements: 1) its past radical and incremental innovation experience and 2) its internal investments in R&D and marketing. We develop and test our hypotheses regarding the relationship between a firm's radical and incremental new product experience, R&D investment intensity and marketing investment intensity, and the likelihood of engaging in exploratory and exploitive licensing agreements. Using data collected from various secondary sources (Recap database, Compustat database, and FDA website), we analyzed technology licensing agreements initiated in the biotechnology and pharmaceutical industries from 1988 to 2011. The results of this study show that incumbents initiate exploratory rather than exploitative licensing agreements when they have more radical innovation experience and when they invest in R&D activities more intensively; in contrast, they initiate exploitative rather than exploratory licensing agreements when they have more incremental innovation experience and when they invest in marketing activities more intensively. The findings of this study contribute to the licensing and interfirm cooperation studies. First, this study lays a foundation to understand the organizational learning aspect of technology licensing agreements. Second, this study sheds lights on how a firm's internal investments in R&D and marketing are linked to its tendency to initiate licensing agreements along the innovation process. Finally, the findings of this study provide important insight to managers regarding which technologies to gain via licensing agreements. This study suggests that firms need to consider their internal investments in R&D and marketing as well as their past innovation experiences when they initiate licensing agreements along the process of new product innovation.

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Utilization of Drone LiDAR for Field Investigation of Facility Collapse Accident (붕괴사고 현장조사를 위한 드론 LiDAR 활용)

  • Yonghan Jung ;Eontaek Lim ;Jaewook Suk;Seul Koo;Seongsam Kim
    • Korean Journal of Remote Sensing
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    • v.39 no.5_2
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    • pp.849-858
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    • 2023
  • Investigating disaster sites such as earthquakes and landslides involves significant risks due to potential secondary disasters like facility collapse. In situations where direct access is challenging, there is a need to develop methods for safely acquiring high-precision 3D disaster information using light detection and ranging (LiDAR) equipped drone survey systems. In this study, the feasibility of using drone LiDAR in disaster scenarios was examined, focusing on the collapse accident at Jeongja Bridge in Bundang-gu, Seongnam City, in April 2023. High-density point clouds for the accident bridge were collected, and the bridge's 3D terrain information was reconstructed and compared to the measurement performance of 10 ground control points. The results showed horizontal and vertical root mean square error values of 0.032 m and 0.055 m, respectively. Additionally, when compared to a point cloud generated using ground LiDAR for the same target area, a vertical difference of approximately 0.08 m was observed, but overall shapes showed minimal discrepancies. Moreover, in terms of overall data acquisition and processing time, drone LiDAR was found to be more efficient than ground LiDAR. Therefore, the use of drone LiDAR in disaster sites with significant risks allows for safe and rapid onsite investigations.

Obstetric Complications by the Accessibility to Local Obstetric Service (지역별 분만서비스 접근도에 따른 산과적 합병증 비교)

  • Choi, Young Hyun;Na, Baeg Ju;Lee, Jin Yong;Hwang, Ji Hye;Lim, Nam Gu;Lee, Seong Ki
    • Journal of agricultural medicine and community health
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    • v.38 no.1
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    • pp.14-24
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    • 2013
  • Objectives: Pregnant women in rural areas do not have access to sufficient obstetric services in their own communities due to the shortage of obstetricians. Therefore, most of these women must seek obstetrician outside of their communities. The purpose of this study was to investigate the relationship between obstetric complications and accessibility to local obstetric care in Korea. Methods: This study was an ecological study in which the unit of analysis was an administrative district. Using Korea National Health Insurance Corporation data, the total number of deliveries and the delivery proportion within and outside of the community from 2001 to 2008 were calculated for 232 administrative districts nationwide. Three outflow levels were categorized based on each district's out-of-community delivery proportion: high outflow (upper one third), moderate outflow (middle one third), and low outflow (lower one third). In addition, three obstetric complication rates (the rate of complications following abortion, ectopic and molar pregnancy, the abortion rate, and the eclampsia rate) were calculated for the 232 districts. One-way ANOVA and multivariate linear regression were used to evaluate obstetric complications among the three outflow levels. Results: The high outflow districts had higher rates of eclampsia and complications following abortion, ectopic, and molar pregnancy compared to the other districts (ANOVA, p<0.05). However, there was no significant difference in the abortion rate among the three groups. Multiple linear regression analysis showed that high outflow districts were statistically significant in the rate of complications following abortion, ectopic and molar pregnancy and eclampsia rate after adjusting for local tax per capita (p<0.01). Conclusion: These results indicate that poor access to local obstetric care correlate with poor obstetric outcomes (delayed or excessive bleeding, embolism, genital tract or pelvic infection, shock or other complications following abortion and ectopic or molar pregnancy, or eclampsia).

Variation Analysis of Distance and Exposure Dose in Radiation Control Area and Monitoring Area according to the Thickness of Radiation Protection Tool Using the Calculation Model: Non-Destructive Test Field (계산 모델을 활용한 방사선방어용 도구 두께에 따른 방사선관리구역 및 감시구역의 거리 및 피폭선량 변화 분석 : 방사선투과검사 분야 중심으로)

  • Gwon, Da Yeong;Park, Chan-hee;Kim, Hye Jin;Kim, Yongmin
    • Journal of the Korean Society of Radiology
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    • v.14 no.3
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    • pp.279-287
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    • 2020
  • Recently, interest in radiation protection is increasing because of the occurrence of accidents related to exposure dose. So, the nuclear safety act provides to install the shields to avoid exceeding the dose limit. In particular, when the worker conducts the non-destructive testing (NDT) without the fixed shielding structure, we should monitor the access to the workplace based on a constant dose rate. However, when we apply for permits for NDT work in these work environments, the consideration factors to the estimation of the distance and exposure dose are not legally specified. Therefore, we developed the excel model that automatically calculates the distance, exposure dose, and cost if we input the factors. We applied the assumption data to this model. As a result of the application, the distance change rate was low when the thickness of the lead blanket and collimator is above 25 mm, 21.5 mm, respectively. However, we didn't consider the scattering and build-up factor. And, we assumed the shape of the lead blanket and collimator. Therefore, if we make up for these limitations and use the actual data, we expect that we can build a database on the distance and exposure dose.