• Clinical and Experimental Pediatrics
• /
• v.56 no.12
• /
• pp.540-544
• /
• 2013

Down syndrome, the most common chromosomal abnormality, may be associated with various neurologic complications such as moyamoya syndrome, cervical spinal cord compression due to atlantoaxial subluxation, and basal ganglia damage, as well as epileptic seizures and stroke. Many cases of Down syndrome accompanied by isolated neurologic manifestations have been reported in children; however, Down syndrome with multiple neurologic conditions is rare. Here, we have reported a case of Down syndrome in a 10-year-old girl who presented with asymptomatic moyamoya syndrome, atlantoaxial subluxation with spinal cord compression, and basal ganglia calcification. To the best of our knowledge, this is the first report of Down syndrome, in a child, which was accompanied by these 3 neurologic complications simultaneously. As seen in this case, patients with Down syndrome may have neurologic conditions without any obvious neurologic symptoms; hence, patients with Down syndrome should be carefully examined for the presence of neurologic conditions.

• Journal of Preventive Medicine and Public Health
• /
• v.15 no.1
• /
• pp.205-211
• /
• 1982

This survey was conducted to find out demage done to the farmers by Agrochemicals in a rural area of Korea from January to October, 1980. Choon Sung Gun, Kang Won Province was the survey area and the 412 males were surveyed among all those that have sprayed agrochemicals during 10 Months in 1980. Obtained results and findings from this survey are summarized as follows; 1. The total spray days of 413 males were 3,114 days and avarage spray days per person were 7.54 days. Also avarage spray hours per person were 4.7 hours. 2. The incidence rate per 100 persons of self-recognized skin manifestation was 12.6 persons and incidence rate per spray day was 2.7 percent. The incidence rate per 100 persons of self-recognized intoxication was 23.0 persons and incidence rate per spray day was 3.6 percent. 3. In cases where mask was not used, when it was syrayed in hot weather, when stronger solution was used, the results were higher percentage in self-recognized intoxication (P<0.01). 4. The symptoms of self-recognized intoxication were headache (55.8%), dizziness (46.9%), nausea (17.7%), fatigue (17.0%), and vomiting (17.0%), 5. Number of intoxication per 100 used standardized unit by agrochemicals was parathion (93.8 spells), sumithion (91.8 spells) and folithion (66.7 spells). 6. Treatment was done by health facility utilization (27 cases), visits to drug store (13 cases) and visits to health center (7 cases).

• The Korean Journal of Food And Nutrition
• /
• v.23 no.4
• /
• pp.435-439
• /
• 2010

The aim of this study was to evaluate the anti-inlfammatory effects of Glycyrrhiza glabra Linne extract on ulcerative colitis induced by 3% dextran sulfate sodium in mice. The experimental animals were divided into six groups: control(normal), DSS-induced colitis(control), 1 mg/kg, 10 mg/kg, and 100 mg/kg of Glycyrrhiza glabra Linne extract, and 150 mg/kg 5-aminosalicylic acid(5-ASA)(positive control). We evaluated the pathological disease activity index(DAI), change in weight, colon mucosa damage and myeloperoxidase(MPO) in colon mucosa. Treatment with 10 mg/kg and 100 mg/kg of Glycyrrhiza glabra Linne extract led to significant loss of body weight, the decrease of MPO activity and clinical symptoms such as DAI and histological change. In particular, 100 mg/kg Glycyrrhiza glabra Linne extract led to markedly greater improvement than 150 mg/kg 5-ASA treatment. These results suggest that Glycyrrhiza glabra mediated anti-inflammatory action on colorectal sites may be a useful therapeutic approach to ulcerative colitis.

• Journal of fish pathology
• /
• v.6 no.2
• /
• pp.197-204
• /
• 1993

Flounder culture has been developed mainly in the western parts of japan, and, to date, following six bacterial diseases have been reported. Bacterial white enteritis occurs in 16 to 30-day-old flounder larvae and often causes mass mortality in seed production. Bacterium named Vibrio sp. INFL invades and multiplies in the mucosae of posterier part of intestine, and causes desquamative enteritis. Gliding bacterial disease occurs mostly in juvenile stage and in spring to summer. Diseased signs are partial discoloration and erosion of skin and fins. Histologically, epidermis are removed, and the causative bacterium, Flexibacter maritimus, multiplies on the surface of demis and invades into the muscular tissue. Vibriosis caused by Vibrio anguillarum and related organisum is one of the well-known diseases among marine fish. Outbreaks of the disease in flounder culture are relatively few, but mass mortalities in fingerlings due to the disease were reported. An outbreak of nocardiosis in the autumn of 1984 has been reported, but since then the disease scarcely occurred. The disease is characterized by formation of abscesses under the skin and white nodes in the gill, heart, spleen and kidney. Streptococcicosis occurs frequently in recent years. Beta-hemolytic streptococcus is the causative bacterium, which possesses the same biochemical and serological characteristics as $\beta$-streptococci isolated from some marine and freshwater fish, and is seemed to related to Streptococcus iniae. Edwardsiellosis is the disease that causes most damage in flounder culture in Japan. Characteristic symptoms are swelling of abdomen and intestinal protrusion from the anus due to accumulation of ascites. Edwardsiella tarda, a well-known pathogen of freshwater fish, is the causative bacterium of the disease.

• Journal of Korean Foot and Ankle Society
• /
• v.24 no.2
• /
• pp.98-101
• /
• 2020

We report on the case of a patient with chronic instability of the ball-and-socket ankle joint. The patient, a 21-year-old male, was diagnosed 10 years previously with chronic instability of the ball-and-socket ankle joint. He underwent Broström procedure and augmentation using a periosteal turn down from the fibula for this chronic instability despite having received conservative treatment since the diagnosis. After the procedure, the clinical symptoms of ankle instability were improved and the patient is being periodically followed-up. We report on this case of using a Broström procedure as a treatment option for patients with instability of the ball-and-socket ankle joint with normal range of foot and normal ankle joint alignment without damage in the joint and cartilage.

• The Journal of Internal Korean Medicine
• /
• v.26 no.2
• /
• pp.498-505
• /
• 2005

Renal failure means irreversible damage and depression of renal function, represented by glomerular filtration rate(GFR). A renal failure patient with uremia and anemia is presented. Anemia, in this patient, appeared before uremia did. A 55 year-old male patient was treated for renal failure with Weilingtang. Improvement was observed in, not only GFR, blood urea nitrogen(BUN), and creatinine, but also in such symptoms as difficulty in urine excretion, dyspepsia and abdominal swelling. But anemia appeared during treatment, so a mixture of Dangguibuxuetang(當歸補血湯) and Xiongguitang(芎歸湯) was prescribed. After this treatment, improvement in hemoglobin, and hematocrit was observed.

• Journal of Korean Medical classics
• /
• v.24 no.1
• /
• pp.85-93
• /
• 2011

Wasting-thirst(消渴) occurs due mainly to dryness-heat(燥熱) which by depleting 'Fluid and Humor'(津液) make symptoms of thirst(口渴) swift digestion with rapid hungering(消穀善饑) frequent urination(小便頻數) according to "Internal Classic"(內經). However, the doctors of those days had a tendency to manage wasting-thirst with herbal drugs of dryness-heat or with drugs that tonifies the kidney. Liu Wansu(劉完素) thought that those kinds of drugs intensify gatro-intestinal dryness-heat and consequently could not be suitable for the patients with wasting-thirst. He said that they had mistaken about the relation between five viscera(五臟) and six climate condition(六氣) and that they did not know thoroughly on the theory of branch and root(標本). For preventing the disease of wasting-thirst, Liu Wansu(劉完素) recommended avoiding gatro-intestinal drying caused by the intake of dryness-heat diet, and warned not to deplete 'Fluid and Humor' due to stress-induced fire(火), not to damage yin qi(陰氣) through severe diseases.

• The Journal of Pediatrics of Korean Medicine
• /
• v.15 no.2
• /
• pp.101-109
• /
• 2001

A clinical observation by the tongue change as a diagnostic method was made on 36 week children visited to Dongeui Oriental Medical Hospital from August. 2001 to December 2001 and the observed results were summarized as follows. 1. Their symptoms have been observed with sequences of Resparatory diseases, Digestive, Neuromotor, Psycho-neurological, Urogenital diseases 2. Distribution of sex : male 22 cases, female 14 cases 3. Distribution of age : 0-6 years 24 cases, 7-18 years 12 cases 4. The texture of tongue was resulted in tongue color in pink-28 cases, red-8 case, and shape in thin-18 cases, swelling-6 cases, a fissured patten-5 cases, a prickly patten-4 cases, and a map patten-3 cases, and fur of the tongue in thin-26 cases, moisten-8 cases, deep-2 cases, and coating color of the tongue in thin and whitish-15 cases, thin and yellowish-9 cases, lack-8 cases, deep and whitish-4 cases. 5. The texture of tongue in connection with weak children was come out mostly normal state and the rest red color, a fissured patten, a prickly patten, deep coating, thin and yellowish etc appeared to cause of slight damage due to exogenous pathogenic fators and due to internal injury.

• Journal of Korean Neurosurgical Society
• /
• v.40 no.2
• /
• pp.117-121
• /
• 2006

The surgical removal of solid deep-seated hemangioblastomas remains challenging, because treatment of these lesions is often complicated by severe bleeding associated with the rich vascularity of this tumor, and by severe neural tissue injury associated with the difficulty of en bloc resection, especially when the tumor is located at the cervicomedullary junction. Therefore, preoperative embolization of deep-seated solid hemangioblastomas may play an important role in successful surgical removal by reducing major bleeding and neural tissue damage. A 24-year-old woman, 28-weeks pregnant, was admitted to our hospital for the evaluation of quadriparesis, and brain magnetic resonance imaging[MRI] revealed intra-axial mass lesion in the cervicomedullary junction. After delivery, her neurologic symptoms became aggravated, and we decided to operate. Preoperative angiography revealed a hypervascular tumor in the posterior fossa, and embolization of the main feeding artery using gelfoam and microcoil, resulted in marked reduction of tumor vascularity. She underwent a midline suboccipital craniotomy involving the removal of the arch of C-1. The tumor was totally removed through a midline myelotomy, and at her 6-month follow-up she walked independently. We report on the combined use of the preoperative embolization of feeding vessels and subsequent operative resection in a patient with a solid hemangioblastoma at the cervicomedullary junction immediately after delivery.

• Journal of the Korean Institute of Oriental Medical Informatics
• /
• v.17 no.1
• /
• pp.257-293
• /
• 2011

"Byun Jeung Rok(辨證錄)" written by Jinsatak(陳士鐸) is composed of 14 volumes. In relation to the contents, it is organized into 126 gates(門) and 770 remaining syndromes(餘證) where internal medicine, external medicine, pediatrics, gynecology(內科 外科 小兒 婦人), etc. are divided into sub-sections of cold damage, cold stroke, wind stroke(傷寒 中寒 中風), etc. He explained the symptom, cause of disease, method of treatment, prescription, construction of prescription, instruction of medicine and prognosis(症狀 病因 治法 處方 處方構成 服用法 預後) thoroughly. This study, as an inquiry of the sec 14 volume pediatrics(小兒), deals with febrile fit cacotrophy vomiting diarrhea(驚疳吐瀉), coprozoic parasite(便蟲), smallpox(痘瘡), eruption(疹症), eating mud(喫泥), fetal toxin(胎毒). It was written very logically so it is easy to understand. The analysis of the symptoms are brief and appropriate. Therefore, it is considered to have significant clinical value for future generations and is applied by them. Finally, this topic was studied in hopes of helping later pediatrics clinical treatment.