• Journal of Acupuncture Research
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• v.34 no.4
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• pp.172-179
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• 2017

Background: This study was designed to evaluate the clinical effectiveness of traditional Korean medicine treatment for lumbar spinal stenosis as assessed by radiological criteria. Methods: This was an observational study of 122 patients who were diagnosed with lumbar spinal stenosis and admitted to Jaseng Hospital between January 2016 and June 2017. They were analyzed according to sex, age, cause of disease, disease stage, length of admission, type of stenosis, morphological grade, and dural sac cross-sectional area. All patients were treated with traditional Korean medicine. Patients were assessed with the Numeric Rating Scale (NRS), Oswestry Disability Index (ODI) and EQ-5D before and after treatment. Results: Regarding the distribution of the factors analyzed, these were of note: more females than males (1:3.52); and highest proportions were age more than 70 years (37.70%), cause of lumbar spinal stenosis unknown (67.21%), and subacute stage (42.62%). Comparing before and after treatment, the NRS score for low back and pelvic pain decreased from $6.14{\pm}1.71$ to $4.28{\pm}1.91$ (p < 0.001), and the NRS score for radiating pain and numbness decreased from $6.27{\pm}1.61$ to $2.02{\pm}1.54$ (p < 0.001). ODI decreased from $46.86{\pm}19.40$ to $33.63{\pm}18.66$ (p < 0.001), and gait-related ODI decreased from $3.34{\pm}1.23$ to $2.80{\pm}1.11$ (p < 0.001). There were no statistically significant differences in improvement of the NRS, ODI, gait-related ODI, and EQ-5D for morphological grade and dural sac cross-sectional area. Conclusion: Traditional Korean medicine is effective treatment for patients with lumbar spinal stenosis. Even in patients with severe radiological findings, it is possible to reduce pain and improve quality of life.

• Journal of the Korean association of regional geographers
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• v.15 no.1
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• pp.115-137
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• 2009

Recently, industrial locations have faced changing trends under the influence of emerging industries as well as advanced new technologies. So the purpose of this study is to analyze the spatial distribution and locational factors of biotechnology industry formed around the Seoul Metropolitan area and Daejeon city, both of which are centers of Korean biotechnology industry, and is also to identifytheir locational characteristics. Major results of this study can be outlined as follows: First, from the mid 1990' s to 2000, Korean biotechnology industry has rapidly developed owing to central and local governmental support policies and systems as well as changes in domestic economic environment due to Korean financial crisis. Secondly, it was found that spatial distribution of Korean biotechnology industry converged on the Seoul Metropolitan area till 1990, but shifted from there to Daejeon and Chungcheong area from 1990 to 2000. Particularly after 2000, positive local governmental efforts to attract biotechnology players have driven the spatial distribution of biotechnology industry to shift from Seoul Metropolitan area and Daejeon or adjacent area gradually to other profitable locations. In terms of locational factors, it was found that the locations of Korean biotechnology industry converged primarily on university or college campus and biotechnology venture center, particularly on locations adjacent to superhighway or expressway. Locational factors varied depending on region, industrial type and business growth phase. Therefore, it is advisable that our central and local government should make and implement practical and useful policies in favor of biotechnology business depending on region, industrial type, business growth phase, rather than depending on uniform locational policies.

• Journal of Haehwa Medicine
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• v.22 no.1
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• pp.129-143
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• 2013

This study was conducted to investigate the residue amount of pesticide on the 41 medicinal herbs in Daejeon area. This study was carried out to monitor the current status of pesticide residues in commercial medicinal herbs for sale of food use in 2012. It was performed using GC/ECD, GC/NPD, HPLC to analyze pesticides residues. Residues of 283 pesticides were analyzed by a simultaneous multiresidue method in 41 medicinal herbs being on sale in Daejeon. The medicinal herbs detected pesticides in 10 of 41 cases, showed a detection rate of 24.39%. The medicinal herbs which exceed the maximum residue limit were five cases as Cnidii Rhizoma, Osterici Radix, Artemisiae Capillaris Herba, Zizyphi Fructus and Alismatis Rhizoma. And pesticide residue of Cnidii Rhizoma and Alismatis Rhizoma exceeds the limit standard presented in only medicine use of KFDA. The residual pesticides which had the high detection rate were Chlopyrifos, Tebuconazole and Endosulfan in the detection of medicinal herbs. For further research, standards of Pesticide Residues in medicinal herbs should be added and more research of pesticide residues in medicinal herbs required. And standards of pesticide residues in medicinal herbs should be applied equally as medicines and food.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.14 no.4
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• pp.322-326
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• 1992

Epiphora is overflow of tears due to obstruction of lacrimal duct. Dacryocystorhinostomy is the most common procedure to eliminate the epiphora secondary to complete or partial obstruction of the nasolacrimal duct. The procedure is to artificially create passage between lacrimal sac and nasal cavity. Especially, epiphora would be accompany often by nasolacrimal duct obstruction when trauma of oromaxillofacial area lead to nasal fracture, medial wall fracture of orbit. Therefore in this case there are many case to perform dacryocystorhinostomy because probing and tubing is difficult to resolve the epiphora. We performed 4 cases of dacryocystorhinostomy for adult nasolacrimal duct obstruction from May 1991 to October 1991. The results were very satisfactory in all the case. Epipora disappeared in all case.

• Journal of Chest Surgery
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• v.42 no.6
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• pp.800-802
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• 2009

A 43-year-old male patient visited our hospital because of intermittent chest pain and exertional dyspnea. This patient was diagnosed as suffering with pulmonary stenosis that was caused by muscle hypertrophy of the subpulmonic area, and the diagnosis was made by performing echocardiography and cardiac catheterization. A sternal foramen of the chest wall was found on the operation field. We report here on this case and we also review the relevant literature.

• The Journal of Korean Medicine
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• v.31 no.3
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• pp.1-7
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• 2010

Objectives: To introduce to TKM scientific dose conversion methods of human to animal or animal to human for new drug investigations. Methods: We searched guidelines of the FDA and KFDA, and compared them with references for drug-dose conversion from various databases such as PubMed and Google. Then, we analyzed the potential issues and problems related to dose conversion in safety documentation of new herbal drugs based on our experiences during Investigational New Drug (IND) applications of TKM. Results: Dose conversion from human to animal or animal to human must be appropriately translated during new drug development. From time to time, investigators have some difficulty in determining the appropriate dose, because of misunderstandings of dose conversion, especially when they estimate starting dose in clinical or animal studies to investigate efficacy, toxicology and mechanisms. Therefore, education of appropriate dose calculation is crucial for investigators. The animal dose should not be extrapolated to humans by a simple conversion method based only on body weight, because many studies suggest the normalization method is based mainly on body surface area (BSA). In general, the body surface area seems to have good correlation among species with several parameters including oxygen utilization, caloric expenditure, basal metabolism, blood volume and circulating plasma protein. Likewise, a safety factor should be taken into consideration when deciding high dose in animal toxicology study. Conclusion: Herein, we explain the significance of dose conversion based on body surface area and starting dose estimation for clinical trials with safety factor.

• Economic and Environmental Geology
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• v.33 no.2
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• pp.101-109
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• 2000

The gravity measurement has been carried out to study the deep geologic structure at 331 gravity stations with an interval of 1∼1.5 km along the national road which crosses the southern part of the Korean peninsula from Pohang to Manripo. The Bouguer gravity anomalies were obtained from the observed gravity values, and interpreted by means of upward continuation using FFT (Fast Fourier Transform), Fourier-series method and nonlinear 2-D inversion method to determine the depths of Conrad and Moho discontinuities. The linear regression relations between elevations and gravity anomalies were also obtained to test isostasy in the study area. The depth of Conrad discontinuty is 13km between Pohang and Daegu, 16.5 km between Kimchon and Okchon, 9.7 km between Okchon and Daejeon, and 16.3 km near Manripo. The depth of Moho discontinuty is 32km between Pohang and Daegu, 35 km between Kimchon and Okchon, 28.7 km between Okchon and Daejeon, 40.5 km between Daejeon and Kongju, and 34.5 km between Kongju and Manripo. The result of testing isotasy indicates that the crust of this area seems to be not in perfect isostatic equilibrium but in a little undercompensated sate.

• KCID journal
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• v.18 no.2
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• pp.3-14
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• 2011

Increased impervious surfaces alter stream hydrology resulting in lower flows during droughts and higher peak flows during floods. Not only urban area but also rural area has been expanded impervious surfaces because of increasing of greenhouses. The main objective of this study was to evaluate the performance of the AnnAGNPS (Annualized Non-Point Source Pollution Model) on the surface runoff characteristics of the Daejeon-Stream watershed, and to predict the hydrological effects due to increasing of impervious surfaces. The model parameters were obtained from the geographical information system (GIS) databases, and additional parameters calibrated with the observed data. The model was calibrated by using 2004 of the runoff data and validated by using 2002 data obtained from WAMIS (Water Management Information System) to compare the simulated results for the study watershed. R2 values and efficiency index (EI) between observed and simulated runoff were 0.78 and 0.80, respectively at the calibration period. In this study, expanding of impervious surfaces such as greenhouses caused increasing of surface runoff, but caused decreasing of total nitrogen and total phosphorus loads.

• Journal of Haehwa Medicine
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• v.10 no.1
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• pp.247-258
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• 2001

The following results were obtained. 1. The Urticaria is similar to the korean medical name of yeun-jin, yum-leu, pung-jin-geu(風疹槐), Pung-sa, Pung-so-yeunjin. 2. The most part of the causes that induce Urticaria are like that, the sup-yeul(濕熱) that caused by the sa-gi(邪氣)'s invasion, food and behavior's fault, is gathering in the gastrointestinal tract. 3. The symptomes are like that, the severe pruritic blisters are spread on the whole body, and the color of the blisters is red or white, and nausea, vomitting, abdominal pain, chest discomfort are induced with the Urticaria. 4. The Su-Chok yangmyong Kyong(手 足陽明經), Chok taeum Kyong(足太陰經) and Chok taeyang Kyong(足太陽經) are used for the acupuncture therapy of Urticaria. 5. The acupuncture points of the Kokchi(曲池), Hyolhae(血海), Chok-Samni(足三里), Samumgyo(三陰交), Hapkok(合谷) are used for the acupuncture therapy of Urticaria. 6. the Pye-area(肺區), Shinmun(神門), dammajin-area(蕁麻疹區), Shinsangsun(腎上腺), Chimbu(枕部) are used for the acupuncture therapy of Urticaria in the ear-acupuncture therapy of Urticaria.

• Journal of the Korean Society for Railway
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• v.16 no.3
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• pp.226-232
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• 2013

Recently, CO2 reduction policies are being promoted as parts of ESSD(Environmentally Sound and Sustainable Development), and many local governments are interested in monorails as a new means of transport. Here we report on a feasibility study for introducing a monorail system by considering the travel demands in the Mt. Bomun area in Daejeon, based on the area's population. The feasibility of a monorail system on Mt.Bomun varies with respect to the demographic scale, mode shares, and operational distances. The strategies introduced here will help identify any tourist spots where local governments are trying to introduce monorail systems as a new system of transit.