• Journal of the Korea Institute of Military Science and Technology
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• v.7 no.3 s.18
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• pp.122-128
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• 2004

Internal blast performance test on developed explosives was carried out. Internal blast means a blast wave in closed chambers like tunnels, bunkers, operation center and chamber of ships. We used Anpa tunnel for our test facility. We performed two series of tests to measure internal blast of developed explosives. Three different kinds of cast PBXs, DXD-09, DXD-10, DXD-18, and conventional explosive, Tritonal, were used in our test. The explosives were cast as a charge of 108mm diameter in a plastic tube of a 3mm thickness. The length of charges 4ere adjusted as a weight 3kg. A melt-cast explosive, tritonal, was used as a reference. Pentolite booster was used. The cylindrical boosters have a 95mm diameter and 47.5mm height. The results showed that there may be some differences between the performances in the air blast tests and those in the internal blast tests. The results showed that DXD-10, the best performance in air blast tests, showed the poorest performance in internal blast among the explosives tested. On the other hand, DXD-18 showed exactly the opposite trend. This is probably due to the highest contents of aluminum and inert binder in DXD-18. DXD-18 has $38\;wt\;\%$ of aluminum and $17\;wt\;\%$ of inert binders.

• Journal of the Korea Institute of Military Science and Technology
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• v.7 no.3 s.18
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• pp.129-139
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• 2004

DXD-19 is a flexible sheet explosive, which is a new polymer-bonded explosives(PBX's). DXD-19 is relatively insensitive and can be extruded into various configurations to be applied to munitions. A typical application includes multi-point initiation for the warhead, cutting/severance devices and transfer lines. The DXD-19 composition employs a binder system derived from the thermoplastic elastomer(HyTemp 4454) containing $5\%$ OH terminated with isocyanate curable for increasing mechanical properties. The use of an elastomer CAB increases its mechanical properties and the use of an energetic plasticizer BDNPF/BDNPA(F/A) improves the process ability as well as energy contents. The composition of the extruded DXD-19 formulation is formed $\%$ weight of $PETN/HyTemp/ATEC/(F/A)/CAB=72\~73/12\~13/6\~7/6\~7/1\~2$. Our safety tests of DXD-19 shows Insensitivity to an impact test and friction test, good thermal stability and excellent mechanical properties.

• Journal of Gastric Cancer
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• v.23 no.4
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• pp.609-621
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• 2023

Purpose: Determination of optimal treatment strategies for HER2-positive advanced gastric cancer (AGC) in randomized trials is necessary despite difficulties in direct comparison between trastuzumab deruxtecan (T-DXd) and nivolumab as third or later-line treatments. Materials and Methods: This single-institution, retrospective study aimed to describe the real-world efficacy and safety of T-DXd and nivolumab as ≥ third line treatments for HER2-positive AGC between March 2016 and May 2022. Overall, 58 patients (median age, 64 years; 69% male) were eligible for the study (T-DXd group, n=20; nivolumab group, n=38). Results: Most patients exhibited a HER2 3+ status (72%) and presented metastatic disease at diagnosis (66%). The response rates of 41 patients with measurable lesions in the T-DXd and nivolumab groups were 50% and 15%, respectively. The T-DXd and nivolumab groups had a median progression-free survival of 4.8 months (95% confidence interval [CI], 3.3, 7.0) and 2.3 months (95% CI, 1.5, 3.5), median overall survival (OS) of 10.8 months (95% CI, 6.9, 23.8) and 11.7 months (95% CI, 7.6, 17.1), and grade 3 or greater adverse event rates of 50% and 2%, respectively. Overall, 64% patients received subsequent treatment. Among 23 patients who received both regimens, the T-DXd-nivolumab and nivolumab-T-DXd groups had a median OS of 14.0 months (95% CI, 5.0, not reached) and 19.3 months (95% CI, 9.5, 25.1), respectively. Conclusions: T-DXd and nivolumab showed distinct efficacy and toxicity profiles as ≥ third line treatments for HER2-positive AGC. Considering the distinct features of each regimen, they may help clinicians personalize optimal treatment approaches for these patients.

• Journal of the Korea Institute of Military Science and Technology
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• v.4 no.1
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• pp.20-29
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• 2001

We recently developed a friability test procedure, which will be used as one of substance tests for Extremely Insensitive Detonating Substances(EIDSs) in Test Series 7 of the United Nations. This test was intended to assess the susceptibility of insensitive explosives to the break-up as high strain rate and subsequent ignition characteristics of the deformed material. We designed an air gun system using the hydro code simulation. The projectile velocities of the gun were in good agreement with those predicted by the hydro code with an inert material. Three different types of explosives, melt castable Comp B, castable plastic bonded explosives(PBXs), and pressable PBXs were tested during the development of the test procedure. Two tastable PBXs, i.e. DXD-09 and DXD-10, which are currently under development as candidate formulations of EIDS were classified as EIDS, since test results with these formulations were far better than the criterion of the UN Test Series 7.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.4C
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• pp.389-395
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• 2007

The Film X-ray and the CCD method of current medical image system have the disadvantages such as required large place and diagnosis time. In this paper, we implement an effective medical image system using TXT-DXD method's digital X-ray detector(DR1000C). The implemented medical image system has advantages of placing efficiency and short diagnosis time. In order to make the image out of the system more effective, we develop an LCD(Liquid Crystal Display) control driver, having the resolution of 1900*1200. And we propose an enhancement unsharp masking method to update image enhancement of DR1000C medical image system, and compare it with the current methods.

• 한국전산유체공학회:학술대회논문집
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• 1998.05a
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• pp.1-14
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• 1998

Underwater explosion properties for TNT, an ideal explosive, and DXD-04, a nonideal explosive, were numerically modeled with a one-dimensional Lagrangian hydrodynamic code. The equation of state parameters for detonation products for TNT and DXD-04 were obtained from the BKW code, assuming complete reaction. Burn of TNT was modeled by using the Chapman-Jouguet(CJ) volume burn technique, a programmed-burn technique, assuming instantaneous detonation reaction. Burn of DXD-04 was modeled by using the same technique and by using the reaction rate calibrated from two-dimensional steady-state detonation experiments. The calculations for TNT reproduced the experimental peak pressure of the shock wave propagating through water with an error of $3.0\%$ and the experimental oscillation period of the bubble formed of detonation products with an error of $2.3\%$. For DXD-04, the CJ volume burn technique could not reproduce the experimental observations. When the reaction rate calibrated from two-dimensional steady-state detonation experimental data, the calculated peak pressure was slightly higher by $7.3\%$ than the experimental data, but the calculated shock profile was in good agreement. The bubble period was reproduced with an error of $1.8\%$. These results demonstrated that underwater explosion properties for an ideal explosive can be predicted by using a programmed burn technique, and that, however, those for a nonideal explosive can be predicted only when a well-calibrated reaction rate is used.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.07b
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• pp.853-856
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• 2002

Present. direct method x-ray conversion detector is studied by abroad medical instrument and country with amorphous Selenium. And we search the method for large area x-ray detector. Amorphous-Selenium based photoreceptor is widely used on the X-ray conversion materials. But amorphous-selenium based x-ray conversion detector is broken by high voltage and leakage defect point. In this paper, We investigated top-electrode distance rate to improve defect point and high voltage broken. The result to appoint to made large area x-ray conversion detector with base data.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2010.06a
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• pp.373-373
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• 2010

본 논문에서는 Display용 PDP(Plasma Display panel)를 디지털 X-ray Detector로 적용하기 위해 Panel 내 Xe gas와 Ne gas의 비율을 달리하며 X-ray에 대한 기본적인 전기적 반응 특성을 연구하였다. 연구에 사용된 panel 은 상용화된 Display용 PDP를 5inch의 크기로 소형화한 sample을 제작하여 사용하였다. 제작된 sample panel의 구조는 기본적으로 Display용 PDP의 구조와 일치한다. 제작된 Sample panel의 X-선 검출기로서의 전기적 특성을 조사하기 위해 기본적인 전기특성인 Dark current, X-ray sensitivity, 그리고 Linearity를 측정하였다. 측정 결과, 진단 범위에서 충분한 전기적 Sensitivity 보이며, 선형적 특성 또한 우수한 결과를 보이는 등 안정된 전기적 동작특성을 보였다. 이러한 결과로부터 기존에 사용되어오던 Display용 PDP에 새로운 X선 변환층을 추가하고, 효율을 더욱 높일 수 있는 구조 변경을 통하여 상용화된 PDP를 디지털 X-선 검출기로서의 적용 가능성을 확인할 수 있었다.

• Journal of the Korea Institute of Military Science and Technology
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• v.8 no.4 s.23
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• pp.120-129
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• 2005

To analyze a blast effect of developed explosives, three different kinds of aluminized tastable explosives and melted cast explosive TNT were used. Conventional explosive TNT was used as a reference. Each tested explosive charge of 340mm diameter spherical type was initiated at the charge center with DXD-65(${\sim}750g$) booster and RP-87 EBW detonator. Thirteen piezo type pressure sensors were located at a range from 4 to 50m away from the charge. From the blast wave profiles, we calculated a peak blast pressure and impulse of the explosion. The calculated pressures and in pulses were converted to TNT Equivalent Weight(TEW) factor by the scaling ]aw method. The average TEW factors based on the blast pressure of TX-01, TX-02, TX-03, TX-04 were 1.298, 1.05, 1.266, 1.274 and the average TEW factors based on impulse were 1.504, 1.686, 1.640, 1.679. From the results, we concluded that TEW factors based on blast pressure and based on impulse of aluminized explosives were superior to TNT. This results are owing to the high contents of aluminum in formulations.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.531-531
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• 2007

현재 널리 사용되고 있는 X선 영상 검출기의 문제점을 해결하기 위해 새로운 연구가 활발히 진행되고 있다. 본 논문에서는 새로운 X선 검출기로써의 가능성 제시를 위해 Display용 PDP(Plasma Display panel)를 디지털 X-ray Detector로 적용하기 위한 기본적인 X-ray에 대한 반응성을 검증하였다. PDP의 X-ray Detector로의 사용 가능성을 보기 위하여, 실험에 사용된 panel은 상용화된(commercial) Display용 PDP의 기본적인 구조와 똑같은 구조의 sample을 제작하여 사용하였다. 제작된 panel은 상판에 Substrate glass와 유전체층, 투명전극을 형성하고, 버스 전극층과 MgO층을 형성하였다. 하판에는 격벽을 제작하고 형광체(R.G.B)층을 형성하고, 어드레스 전극을 형성하여 기존의 Display용 PDP와 똑같은 구조를 지니게 하였다. 이렇게 제작된 panel의 X-선 검출기로서의 전기적 특성물 조사하기 위해 누설전류(Dark current), X선 민감도(X-ray sensitivity), 그리고 선형특성(Linearity)을 측정하였다. 측정 결과, 누설전류가 낮고 X-선 검출기로서의 가능성이 충분한 민감도를 보이며, 선형적 특성 또한 우수한 결과를 보이는 등 안정된 전기적 동작특성을 보였다. 이러한 결과로부터 기존에 사용되어오던 디스플레이용 PDP의 구조적 변경을 통하여 상용화된 PDP룰 디지털 X-선 검출기로서의 적용 가능성을 확인할 수 있었다.