• Title/Summary/Keyword: DT&E

Search Result 142, Processing Time 0.023 seconds

Prophylactic Effects of Bifidobacterium longum HY8001 against Escherichia coli O157:H7 and Salmonella typhimurium DT104 Enteric Infection and Evaluation of Vero Cytotxin Neutralizing Effects (Bifidobacterium longum HY8001 균주의 Escherichia coli O157:H7과 Salmonella typhimurium DT104 장곤 내 감염 예방효과 및 Vero cytotoxin 중화효과)

  • 양수진;윤장원;서근석;구혜정;김소현;배형석;백영진;박용호
    • Microbiology and Biotechnology Letters
    • /
    • v.27 no.5
    • /
    • pp.419-425
    • /
    • 1999
  • Prophylactic effects of Bifidobacterium longum HY8001, Korean isolate, against Escherichia coli O157:H7 and Salmonella typhimurium DT104 enteric infection were examined at four groups of specific pathogen free(SPF)-ICR mouse for each pathogen. B. longum HY8001+B. typhimurium DT104+B. longum HY8001(BL+ST+BL) group and B. longum HY8001+E. coli O157:H7+B. longum HY8001(BL+E+BL) group were fed with B. longum HY8001 before and after E. coli O157:H7 or s. typhimurium DT104 challenge, while B. longum HY8001+S. typhimurium DT104(BL+ST) and B. longum HY8001+e. coli O157:H7(BL+E) groups were fed with B. longum HY8001 only before E. coli O157:H7 or S. typhimurium DT104 challenge. E. coli O157:H7(E) and S. typhimurium DT104(ST) groups were challenged with each pathogen without B. longum HY8001 administration and control groups were administered with phosphate buffered solution(PBS). After the oral administration with B. longum HY8001(109cfu), th emice were challenged with E. coli O157:H7(2$\times$1010cfu) or S. typhimurium DT104(108cfu) and the mortality rate and the fecal shedding of challenged pathogen were also examined define the reactivity of the B. longum HY8001. Production of toxin neutralizing substance(s) of B. longum HY8001 was determined by cell cytotoxicity assay using Vero cells. Fecal shedding of th eS. typhimurium DT104 was significantly decreased in BL+ST+BL group fed with B. longum HY8--1 before and after challenge(p<0.05), while the fecal shedding s of S. typhimurium DT104 in BL+ST and St groups remained more than 106cfu. the protective effect of the B. longum HY8001 against E. coli O157:H7 was significantly high only in BL+E+BL group fed with b. longum Hy8001 before and after E. coli O157:H7 challenge from the result of fecal E. coli O157:H7 isolation rate, mortality rate, and intestinal contents culture to detect E. coli O157:H7. the mortality rate of the BL+e and E groups. The cytopathic effect (CPE) of the Vero cytotoxin (Shiga like toxin I & II) in Vero cell was neutralized in B. longum HY8001 culture supernatant added wells which indicate the presence of soluble Vero cytotxin neutralizing substance(s) in B. longum HY8001 culture suprnatant.

  • PDF

How Does Digital Transformation Improve the Quality of Life? Evidence from Korean Older Adults

  • Moon-Yong Kim
    • International journal of advanced smart convergence
    • /
    • v.13 no.3
    • /
    • pp.205-213
    • /
    • 2024
  • Digital transformation (DT) has gained global attention in various service industries, due to the pervasive nature and proliferation of recent digital technologies. Given that we live in an age of DT, the current research examines the factors influencing the older adults' quality of life due to DT. Specifically, we examine whether the older adults' digital skills (i.e., ability to use applications and self-efficacy in using digital devices) and motivational factors regarding DT (i.e., involvement in DT and need for cognition regarding DT) predict their quality of life due to DT. To answer the research question, we conducted a hierarchical multiple regression analysis using the elderly Korean adults aged 65 or older. The results indicate that the older adults' ability to use applications, self-efficacy in using digital devices, involvement in DT, and need for cognition regarding DT are positively associated with quality of life due to DT. The findings provide important implications to improve the elderly's quality of life due to DT.

A Study on the Improvement Method of DT&E for Company Organized Weapon Systems Research and Development (무기체계 업체주관 연구개발 사업의 개발시험평가 개선방안 고찰)

  • Kim, Sungkyung;Kim, Chandong;HUR, Jangwook
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.18 no.6
    • /
    • pp.721-727
    • /
    • 2015
  • The improvement of the reliability of weapon systems and the reduction of the total life-cycle cost based on the improving of the DT&E system for Company Organized weapon systems research and development are urgently required. The major advanced countries operate test and evaluation centers for military (U.S.), manage a large scale organization of IPT personnel (England) or conduct management of DT&E through a third party organization (France). Based on a survey of experts, an improvement of the DT&E policy in terms of reliability and objectiveness is needed, and management through a third party national defense agency and civilian agency such as the Surion development case is required. In addition, although it appears that efficiency improves when management of DT&E is performed by national defence agencies rather than civilian agencies, it is necessary to proceed by selecting a civilian agency based on competition in the case that it is difficult to select a national defence agency.

Data Technology: New Interdisciplinary Science & Technology (데이터 기술: 지식창조를 위한 새로운 융합과학기술)

  • Park, Sung-Hyun
    • Journal of Korean Society for Quality Management
    • /
    • v.38 no.3
    • /
    • pp.294-312
    • /
    • 2010
  • Data Technology (DT) is a new technology which deals with data collection, data analysis, information generation from data, knowledge generation from modelling and future prediction. DT is a newly emerged interdisciplinary science & technology in this 21st century knowledge society. Even though the main body of DT is applied statistics, it also contains management information system (MIS), quality management, process system analysis and so on. Therefore, it is an interdisciplinary science and technology of statistics, management science, industrial engineering, computer science and social science. In this paper, first of all, the definition of DT is given, and then the effects and the basic properties of DT, the differences between IT and DT, the 6 step process for DT application, and a DT example are provided. Finally, the relationship among DT, e-Statistics and Data Mining is explained, and the direction of DT development is proposed.

Optimization of Ramen Flour Formulation by Mixture Experimental Design (혼합물실험설계법에 의한 라면 밀가루 혼합비의 최적화)

  • Park, Hye Ryong;Lee, Seung Ju
    • Food Engineering Progress
    • /
    • v.15 no.4
    • /
    • pp.297-304
    • /
    • 2011
  • Ramen flour formulation was optimized by applying a mixture experimental design. In the optimization, the overall palatability (OP) of cooked ramen and the rheological properties of selected dough were maximized or minimized. Blended ratios of the ingredients such as Dark Northern Spring (DNS), Hard Red Winter (HRW), and Soft White (SW) were designed on a simplex-lattice. Dough rheological properties were measured by Rapid Visco Analyser (RVA), Farinograph, and Extensograph, and the overall palatability by sensory evaluation. Several principal dough rheological properties such as RVA peak viscosity (PV), Farinograph development time (DT), and Extensograph resistance/extensibility after 45 min (R/E 45 min) were selected to influence the overall palatability by canonical correlation analysis (CCA). Goals of the optimization were given as OP maximized, PV maximized, DT minimized, and R/E at 45 min maximized. The optimization results were found to be DNS 33.3%, HRW 33.3%, and SW 33.3% with OP, 5.825; PV, 587.9 cP; DT, 3.1 min; R/E at 45 min, 2.339 BU/mm.

A Study on Efficient Test & Evaluation Methods in Naval Ship Acquisitions (함정사업 시험평가의 효율적 수행방안에 관한 연구)

  • Kim, Jaeyong;Choi, Woensug;Hong, Sukyoon;Chung, Hyungyun;Song, Jeehun;Im, Wooseok;Kwon, Hyunwung
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.19 no.6
    • /
    • pp.703-711
    • /
    • 2016
  • The purposes of this study is to identify the problems arising from current Test & Evaluation process of the naval ship acquisition program and to suggest methods to increase the acquisition efficiency. Considering that the present rule of developmental test &evaluation(DT&E) and operational test & evaluation(OT&E) has caused an inefficiency effect on the acquisition procedures due to the limited practices on it, the DT&E and OT&E procedures through test & evaluation master plan(TEMP) is proposed based on the selective practices of the defense instruction articles. Also, considering characteristics of naval ship acquisitions, efficient procedure systems are derived through case analysis results by comparing each performances of the system. The suggested methods are able to meet the requirements of the changed acquisition environments and also increase efficiency of acquisition systems by adoption of DT&E and OT&E combined test scheme.

Tele-Manipulation of ROBHAZ-DT2 for Hazard Environment Applications

  • Ryu, Dong-Seok;Lee, Jong-Wha;Yoon, Seong-Sik;Kang, Sung-Chul;Song, Jae-Bok;Kim, Mun-Sang
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 2003.10a
    • /
    • pp.2051-2056
    • /
    • 2003
  • In this paper, a tele-manipulation in explosive ordnance disposal(EOD) applications is discussed. The ROBHAZ-DT2 is developed as a teleoperated mobile manipulator for EOD. In general, it has been thought that the robot must have appropriate functions and accuracy enough to handle the complicated and dangerous mission. However, the research on the ROBHAZ-DT2 revealed that the teleoperation causes more restrictions and difficulties in EOD mission. Thus to solve the problem, a novel user interface for the ROBHAZ-DT2 is developed, in which the operator can interact with various human senses (i.e. visual, auditory and haptic sense). It enables an operator to control the ROBHAZ-DT2 simply and intuitively. A tele-manipulation control scheme for the ROBHAZ-DT2 is also proposed including compliance control via force feedback. It makes the robot adapt itself to circumstances, while the robot faithfully follows a command of the operator. This paper deals with a detailed description on the user interface and the tele-manipulation control for the ROBHAZ-DT2. An EOD demonstration is conducted to verify the validity of the proposed interface and the control scheme.

  • PDF

ON THE CAUCHY PROBLEM FOR SOME ABSTRACT NONLINEAR DIFFERENTIAL EQUATIONS

  • Hamza A.S. Abujabal;Mahmoud M. El-Boral
    • Journal of applied mathematics & informatics
    • /
    • v.3 no.2
    • /
    • pp.279-290
    • /
    • 1996
  • In the present paper we study the Cauchy problem in a Banach space E for an abstract nonlinear differential equation of form $$\frac{d^2u}{dt^2}=-A{\frac{du}{dt}}+B(t)u+f(t, W)$$ where W=($A_1$(t)u, A_2(t)u)..., A_{\nu}(t)u), A_{i}(t),\;i=1,2,...{\nu}$,(B(t), t{\in}I$=[0, b]) are families of closed operators defined on dense sets in E into E, f is a given abstract nonlinear function on $I{\times}E^{\nu}$ into E and -A is a closed linar operator defined on dense set in e into E which generates a semi-group. Further the existence and uniqueness of the solution of the considered Cauchy problem is studied for a wide class of the families ($A_{i}$(t), i =1.2...${\nu}$), (B(t), $t{\in}I$) An application and some properties are also given for the theory of partial diferential equations.

Implementation of Electrochemical Methods for Metrology and Analysis of Nano Electronic Structures of Deep Trench DRAM

  • Zeru, Tadios Tesfu;Schroth, Stephan;Kuecher, Peter
    • JSTS:Journal of Semiconductor Technology and Science
    • /
    • v.12 no.2
    • /
    • pp.219-229
    • /
    • 2012
  • In the course of feasibility study the necessity of implementing electrochemical methods as an inline metrology technique to characterize semiconductor nano structures for a Deep Trench Dynamic Random Access Memory (DT-DRAM) (e.g. ultra shallow junctions USJ) was discussed. Hereby, the state of the art semiconductor technology on the advantages and disadvantages of the most recently used analytical techniques for characterization of nano electronic devices are mentioned. Various electrochemical methods, their measure relationship and correlations to physical quantities are explained. The most important issue of this paper is to prove the novel usefulness of the electrochemical micro cell in the semiconductor industry.

Effective Test & Evaluation Method of Weapon Systems in the Change of Acquisition Environment (획득환경변화(獲得環境變化)에 따른 효율적(效率的)인 무기체계(武器體系) 시험평가(試驗評價) 방법(方案))

  • Yang, Byeong-Hee;Kim, Heung-Bin
    • Journal of the military operations research society of Korea
    • /
    • v.31 no.1
    • /
    • pp.93-106
    • /
    • 2005
  • The complexity of modern weapon systems using the IT(intelligence technology) demands that rapid and effective transition from force requirements to deployment and fielding. Thus this paper deals with the DT&E(developmental test & evaluation), OT&E(operational test & evaluation) and SBT(simulation based test) procedure using the case study in the test & evaluation of weapon systems. This study is aimed to produce the effective test & evaluation method of weapon systems in the change of acquisition environment.